Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension

Journal of the American Heart Association

Volumn 2, Issue 3, 2013, Pages

  Horita, Henrick ^a   Furgeson, Seth B ^a   Ostriker, Allison ^a   Olszewski, Kyle A ^a   Sullivan, Timothy ^b   Villegas, Leah R ^b   Levine, Michelle ^a   Parr, Jane E ^a   Cool, Carlyne D ^a   Nemenoff, Raphael A ^a,b   Weiser Evans, Mary C M ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Hypoxia; Inflammation; Pulmonary hypertension; Remodeling; Smooth muscle

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; HEART RIGHT VENTRICLE HYPERTROPHY; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPOXIA; IMMUNOBLOTTING; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE; WILD TYPE; ANIMAL; ANOXIA; COMPLICATION; HYPERTENSION, PULMONARY; MOUSE; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX; INFLAMMATION; REMODELING; SMOOTH MUSCLE;

ANIMALS; ANOXIA; DISEASE PROGRESSION; HYPERTENSION, PULMONARY; MALE; MICE; MYOCYTES, SMOOTH MUSCLE; PTEN PHOSPHOHYDROLASE; RATS; SEVERITY OF ILLNESS INDEX;

HYPOXIA; INFLAMMATION; PULMONARY HYPERTENSION; REMODELING; SMOOTH MUSCLE;

EID: 84891437723     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000188     Document Type: Article

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