MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: Results of a network bioinformatics approach

Circulation

Volumn 125, Issue 12, 2012, Pages 1520-1532

  Parikh, Victoria N ^a   Jin, Richard C ^a   Rabello, Sabrina ^b,e   Gulbahce, Natali ^b,e,f   White, Kevin ^a   Hale, Andrew ^a   Cottrill, Katherine A ^a   Shaik, Rahamthulla S ^a   Waxman, Aaron B ^a,b,e   Zhang, Ying Yi ^a   Maron, Bradley A ^a   Hartner, Jochen C ^c   Fujiwara, Yuko ^d   Orkin, Stuart H ^d   Haley, Kathleen J ^a   Barabási, Albert László ^g   Loscalzo, Joseph ^a   Chan, Stephen Y ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c TaconicArtemis GmbH   (Germany)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g NONE

Author keywords

microRNA; molecular biology; network biology; pulmonary heart disease; vasculature

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; MICRORNA 21; RHO FACTOR; RHO KINASE; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATION; LUNG PARENCHYMA; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; UPREGULATION; VASODILATATION;

ANIMALS; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; GENE REGULATORY NETWORKS; HUMANS; HYPERTENSION, PULMONARY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84862777565     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.060269     Document Type: Article

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