메뉴 건너뛰기




Volumn , Issue FEB, 2012, Pages

Functional studies of microRNAs in neural stem cells: Problems and perspectives

Author keywords

Let 7; MicroRNA; miR 124; miR 9; Neural stem cells; Neurogenesis

Indexed keywords

LET 7; MICRORNA; MICRORNA 124; MICRORNA 7; MICRORNA 9; UNCLASSIFIED DRUG;

EID: 84862157083     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2012.00014     Document Type: Review
Times cited : (26)

References (99)
  • 1
    • 0036096542 scopus 로고    scopus 로고
    • Identification of neural stem cells in the adult vertebrate brain
    • Bull
    • Alvarez-Buylla, A., Seri, B., and Doetsch, F. (2002). Identification of neural stem cells in the adult vertebrate brain. Brain Res. Bull. 57, 751-758.
    • (2002) Brain Res , vol.57 , pp. 751-758
    • Alvarez-Buylla, A.1    Seri, B.2    Doetsch, F.3
  • 2
    • 67349250445 scopus 로고    scopus 로고
    • Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform
    • Amendola, M., Passerini, L., Pucci, F., Gentner, B., Bacchetta, R., and Nal-dini, L. (2009). Regulated and multiple miRNA and siRNA delivery into primary cells by a lentiviral platform. Mol. Ther. 17, 1039-1052.
    • (2009) Mol. Ther. , vol.17 , pp. 1039-1052
    • Amendola, M.1    Passerini, L.2    Pucci, F.3    Gentner, B.4    Bacchetta, R.5    Nal-dini, L.6
  • 3
    • 78149459254 scopus 로고    scopus 로고
    • Reversible block of mouse neural stem cell differentiation in the absence of Dicer and microRNAs
    • doi:10.1371/journal.pone. 0013453
    • Andersson, T., Rahman, S., Sansom, S. N., Alsio, J. M., Kaneda, M., Smith, J., O'carroll, D., Tarakhovsky, A., and Livesey, F. J. (2010). Reversible block of mouse neural stem cell differentiation in the absence of Dicer and microRNAs. PLoS ONE 5, e13453. doi:10.1371/journal.pone. 0013453
    • (2010) PLoS ONE , vol.5
    • Andersson, T.1    Rahman, S.2    Sansom, S.N.3    Alsio, J.M.4    Kaneda, M.5    Smith, J.6    O'carroll, D.7    Tarakhovsky, A.8    Livesey, F.J.9
  • 4
    • 77950357078 scopus 로고    scopus 로고
    • LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogen-esis in vitro
    • Balzer, E., Heine, C., Jiang, Q., Lee, V. M., and Moss, E. G. (2010). LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogen-esis in vitro. Development 137, 891-900.
    • (2010) Development , vol.137 , pp. 891-900
    • Balzer, E.1    Heine, C.2    Jiang, Q.3    Lee, V.M.4    Moss, E.G.5
  • 5
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel, D. P. (2009). MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 6
    • 78651425546 scopus 로고    scopus 로고
    • MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis
    • Bonev, B., Pisco, A., and Papalop-ulu, N. (2011). MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis. Dev. Cell 20, 19-32
    • (2011) Dev. Cell , vol.20 , pp. 19-32
    • Bonev, B.1    Pisco, A.2    Papalop-ulu, N.3
  • 7
    • 0345064195 scopus 로고    scopus 로고
    • Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes
    • Boutla, A., Delidakis, C., and Tabler, M. (2003). Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res. 31, 4973-4980.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4973-4980
    • Boutla, A.1    Delidakis, C.2    Tabler, M.3
  • 9
    • 33947180884 scopus 로고    scopus 로고
    • A functional study of miR-124 in the developing neural tube
    • Cao, X., Pfaff, S. L., and Gage, F. H. (2007). A functional study of miR-124 in the developing neural tube. Genes Dev. 21, 531-536.
    • (2007) Genes Dev , vol.21 , pp. 531-536
    • Cao, X.1    Pfaff, S.L.2    Gage, F.H.3
  • 10
    • 34548668636 scopus 로고    scopus 로고
    • miChip: a microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes
    • Castoldi, M., Benes, V., Hentze, M. W., and Muckenthaler, M. U. (2007). miChip: a microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes. Methods 43, 146-152.
    • (2007) Methods , vol.43 , pp. 146-152
    • Castoldi, M.1    Benes, V.2    Hentze, M.W.3    Muckenthaler, M.U.4
  • 13
    • 63649138643 scopus 로고    scopus 로고
    • miR-124 regulates adult neurogenesis in the sub-ventricular zone stem cell niche
    • Cheng, L. C., Pastrana, E., Tavazoie, M., and Doetsch, F. (2009). miR-124 regulates adult neurogenesis in the sub-ventricular zone stem cell niche. Nat. Neurosci. 12, 399-408.
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, F.4
  • 15
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco, C., Otto, S., Han, J. J., and Man-del, G. (2006). Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U.S.A. 103, 2422-2427.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Man-del, G.4
  • 16
  • 18
    • 33646715590 scopus 로고    scopus 로고
    • Improved targeting of miRNA with antisense oligonu-cleotides
    • Davis, S., Lollo, B., Freier, S., and Esau, C. (2006). Improved targeting of miRNA with antisense oligonu-cleotides. Nucleic Acids Res. 34, 2294-2304.
    • (2006) Nucleic Acids Res , vol.34 , pp. 2294-2304
    • Davis, S.1    Lollo, B.2    Freier, S.3    Esau, C.4
  • 20
    • 43749120042 scopus 로고    scopus 로고
    • Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    • Davis, T. H., Cuellar, T. L., Koch, S. M., Barker, A. J., Harfe, B. D., McManus, M. T., and Ullian, E. M. (2008). Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J. Neurosci. 28, 4322-4330.
    • (2008) J. Neurosci. , vol.28 , pp. 4322-4330
    • Davis, T.H.1    Cuellar, T.L.2    Koch, S.M.3    Barker, A.J.4    Harfe, B.D.5    McManus, M.T.6    Ullian, E.M.7
  • 21
    • 59749089928 scopus 로고    scopus 로고
    • miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogene-sis in the mouse embryonic neocor-tex
    • De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Han-non, G. J., and Huttner, W. B. (2008). miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogene-sis in the mouse embryonic neocor-tex. Development 135, 3911-3921.
    • (2008) Development , vol.135 , pp. 3911-3921
    • De Pietri Tonelli, D.1    Pulvers, J.N.2    Haffner, C.3    Murchison, E.P.4    Han-non, G.J.5    Huttner, W.B.6
  • 22
    • 77949903674 scopus 로고    scopus 로고
    • MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors
    • Delaloy, C., Liu, L., Lee, J. A., Su, H., Shen, F., Yang, G. Y., Young, W. L., Ivey, K. N., and Gao, F. B. (2010). MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell 6, 323-335.
    • (2010) Cell Stem Cell , vol.6 , pp. 323-335
    • Delaloy, C.1    Liu, L.2    Lee, J.A.3    Su, H.4    Shen, F.5    Yang, G.Y.6    Young, W.L.7    Ivey, K.N.8    Gao, F.B.9
  • 23
    • 80054880093 scopus 로고    scopus 로고
    • A miRNA-based system for selecting and maintaining the pluripotent state in human induced pluripotent stem cells
    • Di Stefano, B., Maffioletti, S. M., Gen-tner, B., Ungaro, F., Schira, G., Nal-dini, L., and Broccoli, V. (2011). A miRNA-based system for selecting and maintaining the pluripotent state in human induced pluripotent stem cells. Stem Cells 29, 1684-1695.
    • (2011) Stem Cells , vol.29 , pp. 1684-1695
    • Di Stefano, B.1    Maffioletti, S.M.2    Gen-tner, B.3    Ungaro, F.4    Schira, G.5    Nal-dini, L.6    Broccoli, V.7
  • 24
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch, F., Caille, I., Lim, D. A., Garcia-Verdugo, J. M., and Alvarez-Buylla, A. (1999). Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97, 703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 25
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
    • Ebert, M. S., Neilson, J. R., and Sharp, P. A. (2007). MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 4, 721-726.
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 29
    • 38649105459 scopus 로고    scopus 로고
    • miR-122 targeting with LNA/27-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates
    • Fabani, M. M., and Gait, M. J. (2008). miR-122 targeting with LNA/27-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates. RNA 14, 336-346.
    • (2008) RNA , vol.14 , pp. 336-346
    • Fabani, M.M.1    Gait, M.J.2
  • 30
    • 78650172834 scopus 로고    scopus 로고
    • Developmentally regulated expression of Sox9 and microRNAs 124, 128 and 23 in neuroepithelial stem cells in the developing spinal cord
    • Farrell, B. C., Power, E. M., and Mc Der-mott, K. W. (2011). Developmentally regulated expression of Sox9 and microRNAs 124, 128 and 23 in neuroepithelial stem cells in the developing spinal cord. Int. J. Dev. Neurosci 29, 31-36.
    • (2011) J. Dev. Neurosci , vol.29 , pp. 31-36
    • Farrell, B.C.1    Power, E.M.2    Mc Der-mott, K.W.3
  • 32
    • 77957194193 scopus 로고    scopus 로고
    • Context-dependent functions of specific microRNAs in neuronal development
    • Gao, F. B. (2010). Context-dependent functions of specific microRNAs in neuronal development. Neural Dev. 5, 25.
    • (2010) Neural Dev , vol.5 , pp. 25
    • Gao, F.B.1
  • 37
    • 33749059160 scopus 로고    scopus 로고
    • miRBase: the microRNA sequence database
    • Griffiths-Jones, S. (2006). miRBase: the microRNA sequence database. Methods Mol Biol. 342,129-138.
    • (2006) Methods Mol Biol , vol.342 , pp. 129-138
    • Griffiths-Jones, S.1
  • 38
    • 84860358888 scopus 로고    scopus 로고
    • Studying microRNAs in the brain: technical lessons learned from the first ten years
    • doi: 10.1016/j.expneurol.2011.12.004. [Epub ahead of print]
    • Hebert, S. S., and Nelson, P. T. (2011). Studying microRNAs in the brain: technical lessons learned from the first ten years. Exp. Neurol. doi: 10.1016/j.expneurol.2011.12.004. [Epub ahead of print].
    • (2011) Exp. Neurol.
    • Hebert, S.S.1    Nelson, P.T.2
  • 40
    • 70350708160 scopus 로고    scopus 로고
    • Different timings of Dicer deletion affect neurogenesis and gli-ogenesis in the developing mouse central nervous system
    • Kawase-Koga, Y., Otaegi, G., and Sun, T. (2009). Different timings of Dicer deletion affect neurogenesis and gli-ogenesis in the developing mouse central nervous system. Dev. Dyn. 238, 2800-2812.
    • (2009) Dev. Dyn. , vol.238 , pp. 2800-2812
    • Kawase-Koga, Y.1    Otaegi, G.2    Sun, T.3
  • 44
    • 33745480963 scopus 로고    scopus 로고
    • Specific microRNAs modulate embryonic stem cell-derived neurogenesis
    • Krichevsky, A. M., Sonntag, K. C., Isac-son, O., and Kosik, K. S. (2006). Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864.
    • (2006) Stem Cells , vol.24 , pp. 857-864
    • Krichevsky, A.M.1    Sonntag, K.C.2    Isac-son, O.3    Kosik, K.S.4
  • 45
    • 84984765629 scopus 로고    scopus 로고
    • Strategies to determine the biological function of microRNAs
    • Krutzfeldt, J., Poy, M. N., and Stoffel, M. (2006). Strategies to determine the biological function of microRNAs. Nat. Genet. 38(Suppl.), S14-S19.
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL.
    • Krutzfeldt, J.1    Poy, M.N.2    Stoffel, M.3
  • 48
    • 78649832226 scopus 로고    scopus 로고
    • A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation
    • Laneve, P., Gioia, U., Andriotto, A., Moretti, F., Bozzoni, I., and Caf-farelli, E. (2010). A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation. Nucleic Acids Res. 38, 6895-6905.
    • (2010) Nucleic Acids Res , vol.38 , pp. 6895-6905
    • Laneve, P.1    Gioia, U.2    Andriotto, A.3    Moretti, F.4    Bozzoni, I.5    Caf-farelli, E.6
  • 52
    • 77956099873 scopus 로고    scopus 로고
    • Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
    • Liu, C., Teng, Z. Q., Santistevan, N. J., Szulwach, K. E., Guo, W., Jin, P., and Zhao, X. (2010). Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 6, 433-444.
    • (2010) Cell Stem Cell , vol.6 , pp. 433-444
    • Liu, C.1    Teng, Z.Q.2    Santistevan, N.J.3    Szulwach, K.E.4    Guo, W.5    Jin, P.6    Zhao, X.7
  • 53
    • 79954587098 scopus 로고    scopus 로고
    • MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1
    • Liu, K., Liu, Y., Mo, W., Qiu, R., Wang, X., Wu, J. Y., and He, R. (2011a). MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1. Nucleic Acids Res. 39, 2869-2879.
    • (2011) Nucleic Acids Res , vol.39 , pp. 2869-2879
    • Liu, K.1    Liu, Y.2    Mo, W.3    Qiu, R.4    Wang, X.5    Wu, J.Y.6    He, R.7
  • 56
    • 19344372003 scopus 로고    scopus 로고
    • No rest for REST: REST/NRSF regulation of neuroge-nesis
    • Lunyak, V. V., and Rosenfeld, M. G. (2005). No rest for REST: REST/NRSF regulation of neuroge-nesis. Cell 121, 499-501.
    • (2005) Cell , vol.121 , pp. 499-501
    • Lunyak, V.V.1    Rosenfeld, M.G.2
  • 58
    • 73249124152 scopus 로고    scopus 로고
    • Promotion of embryonic cortico-cerebral neuronogenesis by miR-124
    • Maiorano, N. A., and Mallamaci, A. (2009). Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 4, 40.
    • (2009) Neural Dev , vol.4 , pp. 40
    • Maiorano, N.A.1    Mallamaci, A.2
  • 59
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neu-ronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev, E. V., Zhang, J., Carrasco, M. A., and Maniatis, T. (2007). The MicroRNA miR-124 promotes neu-ronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27, 435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 62
    • 33745623128 scopus 로고    scopus 로고
    • Post-transcriptional regulation of microRNA expression. RNA
    • Obernosterer, G., Leuschner, P. J., Ale-nius, M., and Martinez, J. (2006). Post-transcriptional regulation of microRNA expression. RNA 12, 1161-1167.
    • (2006) , vol.12 , pp. 1161-1167
    • Obernosterer, G.1    Leuschner, P.J.2    Ale-nius, M.3    Martinez, J.4
  • 63
    • 34250777057 scopus 로고    scopus 로고
    • Locked nucleic acid-based in situ detection of microR-NAs in mouse tissue sections
    • Obernosterer, G., Martinez, J., and Ale-nius, M. (2007). Locked nucleic acid-based in situ detection of microR-NAs in mouse tissue sections. Nat. Protoc. 2, 1508-1514.
    • (2007) Nat. Protoc. , vol.2 , pp. 1508-1514
    • Obernosterer, G.1    Martinez, J.2    Ale-nius, M.3
  • 65
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU
    • Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A.M.,and Weiner, H. L. (2010). MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat. Med. 17, 64-70.
    • (2010) 1 pathway. Nat. Med , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    and Weiner, H.L.5
  • 67
    • 27144543663 scopus 로고    scopus 로고
    • Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs
    • Raymond, C. K., Roberts, B. S., Garrett-Engele, P., Lim, L. P., and Johnson, J. M. (2005). Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs. RNA 11, 1737-1744.
    • (2005) RNA , vol.11 , pp. 1737-1744
    • Raymond, C.K.1    Roberts, B.S.2    Garrett-Engele, P.3    Lim, L.P.4    Johnson, J.M.5
  • 68
    • 33750733621 scopus 로고    scopus 로고
    • A PCR-based method for detection and quantification of small RNAs
    • Ro, S., Park, C., Jin, J., Sanders, K. M., and Yan, W. (2006). A PCR-based method for detection and quantification of small RNAs. Biochem. Bio-phys. Res. Commun. 351, 756-763.
    • (2006) Biochem. Bio-phys. Res. Commun , vol.351 , pp. 756-763
    • Ro, S.1    Park, C.2    Jin, J.3    Sanders, K.M.4    Yan, W.5
  • 70
    • 38149071979 scopus 로고    scopus 로고
    • Evolution, biogene sis, expression, and target predic tions of a substantially expanded set of Drosophila microRNAs
    • Ruby, J. G., Stark, A., Johnston, W. K., Kellis, M., Bartel, D. P., and Lai, E C. (2007). Evolution, biogene sis, expression, and target predic tions of a substantially expanded set of Drosophila microRNAs. Genome Res. 17, 1850-1864.
    • (2007) Genome Res , vol.17 , pp. 1850-1864
    • Ruby, J.G.1    Stark, A.2    Johnston, W.K.3    Kellis, M.4    Bartel, D.P.5    Lai, E.C.6
  • 71
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak, A., Fuchs, H., Smirnova, L., Brandt, C., Pohl, E. E., Nitsch, R., and Wulczyn, F. G. (2008). A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat. Cell Biol. 10, 987-993.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 76
    • 55249102500 scopus 로고    scopus 로고
    • MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium
    • Shibata, M., Kurokawa, D., Nakao, H., Ohmura, T., and Aizawa, 5 (2008). MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J. Neurosci. 28, 10415-10421.
    • (2008) J. Neurosci. , vol.28 , pp. 10415-10421
    • Shibata, M.1    Kurokawa, D.2    Nakao, H.3    Ohmura, T.4    Aizawa S5
  • 77
    • 79952267171 scopus 로고    scopus 로고
    • MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors
    • Shibata, M., Nakao, H., Kiyonari, H., Abe, T., and Aizawa, S. (2011). MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J. Neurosci. 31, 3407-3422.
    • (2011) J. Neurosci. , vol.31 , pp. 3407-3422
    • Shibata, M.1    Nakao, H.2    Kiyonari, H.3    Abe, T.4    Aizawa, S.5
  • 82
    • 39149098467 scopus 로고    scopus 로고
    • Profiling of microRNA expression by mRAP
    • Takada, S., and Mano, H. (2007). Profiling of microRNA expression by mRAP. Nat. Protoc. 2, 3136-3145.
    • (2007) Nat. Protoc. , vol.2 , pp. 3136-3145
    • Takada, S.1    Mano, H.2
  • 84
    • 16544365954 scopus 로고    scopus 로고
    • Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
    • Valoczi, A., Hornyik, C., Varga, N., Burgyan, J., Kauppinen, S., and Havelda, Z. (2004). Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. Nucleic Acids Res. 32, e175.
    • (2004) Nucleic Acids Res , vol.32
    • Valoczi, A.1    Hornyik, C.2    Varga, N.3    Burgyan, J.4    Kauppinen, S.5    Havelda, Z.6
  • 85
    • 34247589595 scopus 로고    scopus 로고
    • Control of stress-dependent cardiac growth and gene expression by a microRNA
    • van Rooij, E., Sutherland, L. B., Qi, X., Richardson, J. A., Hill, J., and Olson, E. N. (2007). Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316, 575-579.
    • (2007) Science , vol.316 , pp. 575-579
    • van Rooij, E.1    Sutherland, L.B.2    Qi, X.3    Richardson, J.A.4    Hill, J.5    Olson, E.N.6
  • 86
    • 6344277190 scopus 로고    scopus 로고
    • LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA
    • Vester, B., and Wengel, J. (2004). LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA. Biochemistry 43, 13233-13241.
    • (2004) Biochemistry , vol.43 , pp. 13233-13241
    • Vester, B.1    Wengel, J.2
  • 87
    • 34147157651 scopus 로고    scopus 로고
    • ThemicroRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
    • Visvanathan, J., Lee, S., Lee, B., Lee, J. W., andLee, S. K.(2007).ThemicroRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749.
    • (2007) Genes Dev , vol.21 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.K.5
  • 89
    • 34248650941 scopus 로고    scopus 로고
    • In situ detection of animal and plant microRNAs
    • Wheeler, G., Valoczi, A., Havelda, Z., and Dalmay, T. (2007). In situ detection of animal and plant microRNAs. DNA Cell Biol. 26, 251-255.
    • (2007) DNA Cell Biol , vol.26 , pp. 251-255
    • Wheeler, G.1    Valoczi, A.2    Havelda, Z.3    Dalmay, T.4
  • 93
    • 0035257203 scopus 로고    scopus 로고
    • Neural plate patterning: upstream and downstream of the isthmic organizer
    • Wurst, W., and Bally-Cuif, L. (2001). Neural plate patterning: upstream and downstream of the isthmic organizer. Nat. Rev. Neurosci. 2, 99-108.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 99-108
    • Wurst, W.1    Bally-Cuif, L.2
  • 95
    • 48849103603 scopus 로고    scopus 로고
    • MicroRNA miR-124 regulates neurite outgrowth during neu-ronal differentiation
    • Yu, J. Y., Chung, K. H., Deo, M., Thompson, R. C., and Turner, D. L. (2008). MicroRNA miR-124 regulates neurite outgrowth during neu-ronal differentiation. Exp. Cell Res. 314, 2618-2633.
    • (2008) Exp. Cell Res. , vol.314 , pp. 2618-2633
    • Yu, J.Y.1    Chung, K.H.2    Deo, M.3    Thompson, R.C.4    Turner, D.L.5
  • 96
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao, C., Deng, W., and Gage, F. H. (2008). Mechanisms and functional implications of adult neurogenesis. Cell 132, 645-660.
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3
  • 97
    • 76649088031 scopus 로고    scopus 로고
    • MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
    • Zhao, C., Sun, G., Li, S., Lang, M. F., Yang, S., Li, W., and Shi, Y. (2010). MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl. Acad. Sci. U.S.A. 107, 1876-1881.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 1876-1881
    • Zhao, C.1    Sun, G.2    Li, S.3    Lang, M.F.4    Yang, S.5    Li, W.6    Shi, Y.7
  • 98
    • 64049095014 scopus 로고    scopus 로고
    • A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
    • Zhao, C., Sun, G., Li, S., and Shi, Y. (2009). A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat. Struct. Mol. Biol. 16, 365-371.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 365-371
    • Zhao, C.1    Sun, G.2    Li, S.3    Shi, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.