Astrocytic therapies for neuronal repair in stroke

Neuroscience Letters

Volumn 565, Issue , 2014, Pages 47-52

  Gleichman, Amy J ^a   Carmichael, S Thomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocytes; Neural repair; Stroke

Indexed keywords

ANGIOGENESIS; ASTROCYTE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; CELL REGENERATION; CELL TRANSPLANTATION; CEREBROVASCULAR ACCIDENT; EXCITOTOXICITY; HUMAN; NERVE CELL; NERVE SPROUTING; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYNAPTOGENESIS;

ASTROCYTES; NEURAL REPAIR; STROKE;

ANIMALS; ASTROCYTES; AXONS; BLOOD-BRAIN BARRIER; CELL PROLIFERATION; HUMANS; INFLAMMATION; NEOVASCULARIZATION, PHYSIOLOGIC; NEURONS; STROKE; SYNAPSES;

EID: 84897102991     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.10.055     Document Type: Review

References (52)

1. Abulrob A., Brunette E., Slinn J., Baumann E., Stanimirovic D. Dynamic analysis of the blood-brain barrier disruption in experimental stroke using time domain in vivo fluorescence imaging. Mol. Imaging 2008, 7:248-262.
2. Acler M., Manganotti P. Role, indications and controversies of levodopa administration in chronic stroke patients. Eur. J. Phys. Rehabil. Med. 2013, 49:243-249.
3. Adelson J.D., Barreto G.E., Xu L., Kim T., Brott B.K., Ouyang Y.B., Naserke T., Djurisic M., Xiong X., Shatz C.J., Giffard R.G. Neuroprotection from stroke in the absence of MHCI or PirB. Neuron 2012, 73:1100-1107.
4. Al-Ahmad A.J., Lee B., Saini M., Bix G.J. Perlecan domain V modulates astrogliosis in vitro and after focal cerebral ischemia through multiple receptors and increased nerve growth factor release. Glia 2011, 59:1822-1840.
5. Alvarez J.I., Dodelet-Devillers A., Kebir H., Ifergan I., Fabre P.J., Terouz S., Sabbagh M., Wosik K., Bourbonniere L., Bernard M., van Horssen J., de Vries H.E., Charron F., Prat A. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science 2011, 334:1727-1731.
6. Barreto G.E., White R.E., Ouyang Y., Xu L., Giffard R.G. Astrocytes: targets for neuroprotection in stroke. Cent. Nerv. Syst. Agents Med. Chem. 2011, 11:164-173.
7. Barreto G.E., White R.E., Xu L., Palm C.J., Giffard R.G. Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse. Exp. Neurol. 2012, 238:284-296.
8. Bejot Y., Prigent-Tessier A., Cachia C., Giroud M., Mossiat C., Bertrand N., Garnier P., Marie C. Time-dependent contribution of non neuronal cells to BDNF production after ischemic stroke in rats. Neurochem. Int. 2011, 58:102-111.
9. Benner E.J., Luciano D., Jo R., Abdi K., Paez-Gonzalez P., Sheng H., Warner D.S., Liu C., Eroglu C., Kuo C.T. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature 2013, 497:369-373.
10. Carbone M., Duty S., Rattray M. Riluzole elevates GLT-1 activity and levels in striatal astrocytes. Neurochem. Int. 2012, 60:31-38.
11. Carmichael S.T. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2005, 2:396-409.
12. Christopherson K.S., Ullian E.M., Stokes C.C., Mullowney C.E., Hell J.W., Agah A., Lawler J., Mosher D.F., Bornstein P., Barres B.A. Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell 2005, 120:421-433.
13. Cui X., Chopp M., Zacharek A., Cui Y., Roberts C., Chen J. The neurorestorative benefit of GW3965 treatment of stroke in mice. Stroke 2013, 44:153-161.
14. Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., Borden W.B., Bravata D.M., Dai S., Ford E.S., Fox C.S., Franco S., Fullerton H.J., Gillespie C., Hailpern S.M., Heit J.A., Howard V.J., Huffman M.D., Kissela B.M., Kittner S.J., Lackland D.T., Lichtman J.H., Lisabeth L.D., Magid D., Marcus G.M., Marelli A., Matchar D.B., McGuire D.K., Mohler E.R., Moy C.S., Mussolino M.E., Nichol G., Paynter N.P., Schreiner P.J., Sorlie P.D., Stein J., Turan T.N., Virani S.S., Wong N.D., Woo D., Turner M.B. Heart disease and stroke statistics - 2013 update: a report from the American Heart Association. Circulation 2013, 127:e6-e245.
15. Guirland C., Zheng J.Q. Membrane lipid rafts and their role in axon guidance. Adv. Exp. Med. Biol. 2007, 621:144-155.
16. Harvey B.K., Airavaara M., Hinzman J., Wires E.M., Chiocco M.J., Howard D.B., Shen H., Gerhardt G., Hoffer B.J., Wang Y. Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke. PLoS ONE 2011, 6:e22135.
17. Hayakawa K., Pham L.D., Katusic Z.S., Arai K., Lo E.H. Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:7505-7510.
18. Hayakawa K., Qiu J., Lo E.H. Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann. N. Y. Acad. Sci. 2010, 1207:50-57.
19. He Q.W., Xia Y.P., Chen S.C., Wang Y., Huang M., Huang Y., Li J.Y., Li Y.N., Gao Y., Mao L., Mei Y.W., Hu B. Astrocyte-derived sonic hedgehog contributes to angiogenesis in brain microvascular endothelial cells via RhoA/ROCK pathway after oxygen-glucose deprivation. Mol. Neurobiol. 2013, 47:976-987.
20. Jiang P., Chen C., Wang R., Chechneva O.V., Chung S.H., Rao M.S., Pleasure D.E., Liu Y., Zhang Q., Deng W. hESC-derived Olig2(+) progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nat. Commun. 2013, 4:2196.
21. Kang S.S., Keasey M.P., Arnold S.A., Reid R., Geralds J., Hagg T. Endogenous CNTF mediates stroke-induced adult CNS neurogenesis in mice. Neurobiol. Dis. 2012, 49C:68-78.
22. Kang S.S., Keasey M.P., Cai J., Hagg T. Loss of neuron-astroglial interaction rapidly induces protective CNTF expression after stroke in mice. J. Neurosci. 2012, 32:9277-9287.
23. Keene S.D., Greco T.M., Parastatidis I., Lee S.H., Hughes E.G., Balice-Gordon R.J., Speicher D.W., Ischiropoulos H. Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome. Proteomics 2009, 9:768-782.
24. Kostandy B.B. The role of glutamate in neuronal ischemic injury: the role of spark in fire. Neurol. Sci. 2012, 33:223-237.
25. Kumpers P., Gueler F., David S., Slyke P.V., Dumont D.J., Park J.K., Bockmeyer C.L., Parikh S.M., Pavenstadt H., Haller H., Shushakova N. The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis. Crit. Care 2011, 15:R261.
26. Kuric E., Wieloch T., Ruscher K. Dopamine receptor activation increases glial cell line-derived neurotrophic factor in experimental stroke. Exp. Neurol. 2013, 247:202-208.
27. Lee B., Clarke D., Al Ahmad A., Kahle M., Parham C., Auckland L., Shaw C., Fidanboylu M., Orr A.W., Ogunshola O., Fertala A., Thomas S.A., Bix G.J. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents. J. Clin. Invest. 2011, 121:3005-3023.
28. Liauw J., Hoang S., Choi M., Eroglu C., Choi M., Sun G.H., Percy M., Wildman-Tobriner B., Bliss T., Guzman R.G., Barres B.A., Steinberg G.K. Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke. J. Cereb. Blood Flow Metab. 2008, 28:1722-1732.
29. Munakata M., Shirakawa H., Nagayasu K., Miyanohara J., Miyake T., Nakagawa T., Katsuki H., Kaneko S. Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice. Stroke 2013, 44:1981-1987.
30. Newman G.C., Bang H., Hussain S.I., Toole J.F. Association of diabetes, homocysteine, and HDL with cognition and disability after stroke. Neurology 2007, 69:2054-2062.
31. Noberini R., Lamberto I., Pasquale E.B. Targeting Eph receptors with peptides and small molecules: progress and challenges. Semin. Cell Dev. Biol. 2012, 23:51-57.
32. Novotny N.M., Lahm T., Markel T.A., Crisostomo P.R., Wang M., Wang Y., Tan J., Meldrum D.R. Angiopoietin-1 in the treatment of ischemia and sepsis. Shock 2009, 31:335-341.
33. Overman J.J., Clarkson A.N., Wanner I.B., Overman W.T., Eckstein I., Maguire J.L., Dinov I.D., Toga A.W., Carmichael S.T. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:E2230-E2239.
34. Pulsinelli W.A., Brierley J.B. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 1979, 10:267-272.
35. Rao V.L., Bowen K.K., Dempsey R.J. Transient focal cerebral ischemia down-regulates glutamate transporters GLT-1 and EAAC1 expression in rat brain. Neurochem. Res. 2001, 26:497-502.
36. Rao V.L., Dogan A., Todd K.G., Bowen K.K., Kim B.T., Rothstein J.D., Dempsey R.J. Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain. J. Neurosci. 2001, 21:1876-1883.
37. Ruscher K., Shamloo M., Rickhag M., Ladunga I., Soriano L., Gisselsson L., Toresson H., Ruslim-Litrus L., Oksenberg D., Urfer R., Johansson B.B., Nikolich K., Wieloch T. The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Brain 2011, 134:732-746.
38. Sahota P., Savitz S.I. Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics 2011, 8:434-451.
39. Scheidtmann K., Fries W., Muller F., Koenig E. Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: a prospective, randomised, double-blind study. Lancet 2001, 358:787-790.
40. Shao W., Zhang S.Z., Tang M., Zhang X.H., Zhou Z., Yin Y.Q., Zhou Q.B., Huang Y.Y., Liu Y.J., Wawrousek E., Chen T., Li S.B., Xu M., Zhou J.N., Hu G., Zhou J.W. Suppression of neuroinflammation by astrocytic dopamine D2 receptors via alphaB-crystallin. Nature 2013, 494:90-94.
41. Sofroniew M.V. Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci. 2009, 32:638-647.
42. Sofroniew M.V., Vinters H.V. Astrocytes: biology and pathology. Acta Neuropathol. 2010, 119:7-35.
43. Sukumari-Ramesh S., Alleyne C.H., Dhandapani K.M. Astrocyte-specific expression of survivin after intracerebral hemorrhage in mice: a possible role in reactive gliosis?. J. Neurotrauma 2012, 29:2798-2804.
44. Weng Y.C., Kriz J. Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia. Exp. Neurol. 2007, 204:433-442.
45. Wilson J.R., Fehlings M.G. Riluzole for acute traumatic spinal cord injury: a promising neuroprotective treatment strategy. World Neurosurg. 2013.
46. Xia Y.P., He Q.W., Li Y.N., Chen S.C., Huang M., Wang Y., Gao Y., Huang Y., Wang M.D., Mao L., Hu B. Recombinant human sonic hedgehog protein regulates the expression of ZO-1 and occludin by activating angiopoietin-1 in stroke damage. PLoS ONE 2013, 8:e68891.
47. Yan M., Dai H., Ding T., Dai A., Zhang F., Yu L., Chen G., Chen Z. Effects of dexmedetomidine on the release of glial cell line-derived neurotrophic factor from rat astrocyte cells. Neurochem. Int. 2011, 58:549-557.
48. Yu S.W., Friedman B., Cheng Q., Lyden P.D. Stroke-evoked angiogenesis results in a transient population of microvessels. J. Cereb. Blood Flow Metab. 2007, 27:755-763.
49. Zamanian J.L., Xu L., Foo L.C., Nouri N., Zhou L., Giffard R.G., Barres B.A. Genomic analysis of reactive astrogliosis. J. Neurosci. 2012, 32:6391-6410.
50. Zhang X., Lawler J. Thrombospondin-based antiangiogenic therapy. Microvasc. Res. 2007, 74:90-99.
51. Zhang Y., Jin Y., Behr M.J., Feustel P.J., Morrison J.P., Kimelberg H.K. Behavioral and histological neuroprotection by tamoxifen after reversible focal cerebral ischemia. Exp. Neurol. 2005, 196:41-46.
52. Zhao Y., Rempe D.A. Targeting astrocytes for stroke therapy. Neurotherapeutics 2010, 7:439-451.