메뉴 건너뛰기




Volumn 32, Issue 42, 2012, Pages 14489-14510

Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; CALCIUM ION; CD40 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; ENDOTHELIN A RECEPTOR; ENDOTOXIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 30; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y6 RECEPTOR; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84867586343     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1256-12.2012     Document Type: Article
Times cited : (168)

References (71)
  • 2
    • 0030905019 scopus 로고    scopus 로고
    • Expression of various TGF-beta isoforms and type I receptor in necrotizing human brain lesions
    • Ata AK, Funa K, Olsson Y (1997) Expression of various TGF-beta isoforms and type I receptor in necrotizing human brain lesions. Acta Neuropathol 93:326-333.
    • (1997) Acta Neuropathol , vol.93 , pp. 326-333
    • Ata, A.K.1    Funa, K.2    Olsson, Y.3
  • 4
    • 55049084760 scopus 로고    scopus 로고
    • The mystery and magic of glia: A perspective on their roles in health and disease
    • Barres BA (2008) The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 60:430-440.
    • (2008) Neuron , vol.60 , pp. 430-440
    • Barres, B.A.1
  • 5
    • 22344431751 scopus 로고    scopus 로고
    • Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    • Brambilla R, Bracchi-Ricard V, Hu WH, Frydel B, Bramwell A, Karmally S, Green EJ, Bethea JR (2005) Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J Exp Med 202:145-156.
    • (2005) J Exp Med , vol.202 , pp. 145-156
    • Brambilla, R.1    Bracchi-Ricard, V.2    Hu, W.H.3    Frydel, B.4    Bramwell, A.5    Karmally, S.6    Green, E.J.7    Bethea, J.R.8
  • 6
  • 8
    • 77955089959 scopus 로고    scopus 로고
    • CXCR4-mediated glutamate exocytosis from astrocytes
    • Calì C, Bezzi P (2010) CXCR4-mediated glutamate exocytosis from astrocytes. J Neuroimmunol 224:13-21.
    • (2010) J Neuroimmunol , vol.224 , pp. 13-21
    • Calì, C.1    Bezzi, P.2
  • 10
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham DE (2007) Calcium signaling. Cell 131:1047-1058.
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 11
    • 80054739524 scopus 로고    scopus 로고
    • Designing, performing, and interpreting a microarraybased gene expression study
    • Coppola G (2011) Designing, performing, and interpreting a microarraybased gene expression study. Methods Mol Biol 793:417-439.
    • (2011) Methods Mol Biol , vol.793 , pp. 417-439
    • Coppola, G.1
  • 12
    • 67249133451 scopus 로고    scopus 로고
    • Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia
    • Coppola G, Marmolino D, Lu D, Wang Q, Cnop M, Rai M, Acquaviva F, Cocozza S, Pandolfo M, Geschwind DH (2009) Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia. Hum Mol Genet 18:2452-2461.
    • (2009) Hum Mol Genet , vol.18 , pp. 2452-2461
    • Coppola, G.1    Marmolino, D.2    Lu, D.3    Wang, Q.4    Cnop, M.5    Rai, M.6    Acquaviva, F.7    Cocozza, S.8    Pandolfo, M.9    Geschwind, D.H.10
  • 14
    • 60849089605 scopus 로고    scopus 로고
    • In inflammatory reactive astrocytes co-cultured with brain endothelial cells nicotineevoked Ca(2+) transients are attenuated due to interleukin-1beta release and rearrangement of actin filaments
    • Delbro D, Westerlund A, Björklund U, Hansson E (2009) In inflammatory reactive astrocytes co-cultured with brain endothelial cells nicotineevoked Ca(2+) transients are attenuated due to interleukin-1beta release and rearrangement of actin filaments. Neuroscience 159:770-779.
    • (2009) Neuroscience , vol.159 , pp. 770-779
    • Delbro, D.1    Westerlund, A.2    Björklund, U.3    Hansson, E.4
  • 15
    • 0029117646 scopus 로고
    • Adrenergic calcium signaling in astrocyte networks within the hippocampal slice
    • Duffy S, MacVicar BA (1995) Adrenergic calcium signaling in astrocyte networks within the hippocampal slice. J Neurosci 15:5535-5550.
    • (1995) J Neurosci , vol.15 , pp. 5535-5550
    • Duffy, S.1    Macvicar, B.A.2
  • 16
    • 0030044514 scopus 로고    scopus 로고
    • In vitro ischemia promotes calcium influx and intracellular calcium release in hippocampal astrocytes
    • Duffy S, MacVicar BA (1996) In vitro ischemia promotes calcium influx and intracellular calcium release in hippocampal astrocytes. J Neurosci 16:71-81.
    • (1996) J Neurosci , vol.16 , pp. 71-81
    • Duffy, S.1    Macvicar, B.A.2
  • 17
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes-implications for their role in neurological disease
    • Eddleston M, Mucke L (1993) Molecular profile of reactive astrocytes-implications for their role in neurological disease. Neuroscience 54:15-36.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 18
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30:207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 21
    • 79955681508 scopus 로고    scopus 로고
    • Molecular cascades that mediate the influence of inflammation on epilepsy
    • Friedman A, Dingledine R (2011) Molecular cascades that mediate the influence of inflammation on epilepsy. Epilepsia 52 [Suppl 3]:33-39.
    • (2011) Epilepsia , vol.52 , Issue.SUPPL. 3 , pp. 33-39
    • Friedman, A.1    Dingledine, R.2
  • 22
  • 24
    • 77951929051 scopus 로고    scopus 로고
    • Integrated brain circuits: Astrocytic networks modulate neuronal activity and behavior
    • Halassa MM, Haydon PG (2010) Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol 72: 335-355.
    • (2010) Annu Rev Physiol , vol.72 , pp. 335-355
    • Halassa, M.M.1    Haydon, P.G.2
  • 25
    • 77957090798 scopus 로고    scopus 로고
    • Reactive astrocytes as therapeutic targets for CNS disorders
    • Hamby ME, Sofroniew MV (2010) Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics 7:494-506.
    • (2010) Neurotherapeutics , vol.7 , pp. 494-506
    • Hamby, M.E.1    Sofroniew, M.V.2
  • 26
    • 33749018555 scopus 로고    scopus 로고
    • TGF-beta1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS-2
    • Hamby ME, Hewett JA, Hewett SJ (2006a) TGF-beta1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS-2. Glia 54:566-577.
    • (2006) Glia , vol.54 , pp. 566-577
    • Hamby, M.E.1    Hewett, J.A.2    Hewett, S.J.3
  • 27
    • 28844446890 scopus 로고    scopus 로고
    • Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes
    • Hamby ME, Uliasz TF, Hewett SJ, Hewett JA (2006b) Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes. J Neurosci Methods 150:128-137.
    • (2006) J Neurosci Methods , vol.150 , pp. 128-137
    • Hamby, M.E.1    Uliasz, T.F.2    Hewett, S.J.3    Hewett, J.A.4
  • 28
    • 39649090959 scopus 로고    scopus 로고
    • TGF-beta1 reduces the heterogeneity of astrocytic cyclooxygenase-2 and nitric oxide synthase-2 gene expression in a stimulus-independent manner
    • Hamby ME, Hewett JA, Hewett SJ (2008) TGF-beta1 reduces the heterogeneity of astrocytic cyclooxygenase-2 and nitric oxide synthase-2 gene expression in a stimulus-independent manner. Prostaglandins Other Lipid Mediat 85:115-124.
    • (2008) Prostaglandins Other Lipid Mediat , vol.85 , pp. 115-124
    • Hamby, M.E.1    Hewett, J.A.2    Hewett, S.J.3
  • 29
    • 77956530090 scopus 로고    scopus 로고
    • Smad3-dependent signaling underlies the TGF-beta1-mediated enhancement in astrocytic iNOS expression
    • Hamby ME, Hewett JA, Hewett SJ (2010) Smad3-dependent signaling underlies the TGF-beta1-mediated enhancement in astrocytic iNOS expression. Glia 58:1282-1891.
    • (2010) Glia , vol.58 , pp. 1282-1891
    • Hamby, M.E.1    Hewett, J.A.2    Hewett, S.J.3
  • 31
    • 84856739147 scopus 로고    scopus 로고
    • Microglia are required for astroglial toll-like receptor 4 response and for optimal TLR2 and TLR3 response
    • Holm TH, Draeby D, Owens T (2012) Microglia are required for astroglial toll-like receptor 4 response and for optimal TLR2 and TLR3 response. Glia 60:630-638.
    • (2012) Glia , vol.60 , pp. 630-638
    • Holm, T.H.1    Draeby, D.2    Owens, T.3
  • 32
    • 35548969443 scopus 로고    scopus 로고
    • Glial regulation of the cerebral microvasculature
    • Iadecola C, Nedergaard M (2007) Glial regulation of the cerebral microvasculature. Nat Neurosci 10:1369-1376.
    • (2007) Nat Neurosci , vol.10 , pp. 1369-1376
    • Iadecola, C.1    Nedergaard, M.2
  • 34
    • 0037309385 scopus 로고    scopus 로고
    • Cytokines: Powerful regulators of glial cell activation
    • John GR, Lee SC, Brosnan CF (2003) Cytokines: Powerful regulators of glial cell activation. Neuroscientist 9:10-22.
    • (2003) Neuroscientist , vol.9 , pp. 10-22
    • John, G.R.1    Lee, S.C.2    Brosnan, C.F.3
  • 35
    • 13244269848 scopus 로고    scopus 로고
    • IL-1-regulated responses in astrocytes: Relevance to injury and recovery
    • John GR, Lee SC, Song X, Rivieccio M, Brosnan CF (2005) IL-1-regulated responses in astrocytes: relevance to injury and recovery. Glia 49:161-176.
    • (2005) Glia , vol.49 , pp. 161-176
    • John, G.R.1    Lee, S.C.2    Song, X.3    Rivieccio, M.4    Brosnan, C.F.5
  • 37
    • 0029879741 scopus 로고    scopus 로고
    • Increased expression of TGF-beta 1 in brain tissue after ischemic stroke in humans
    • Krupinski J, Kumar P, Kumar S, Kaluza J (1996) Increased expression of TGF-beta 1 in brain tissue after ischemic stroke in humans. Stroke 27: 852-857.
    • (1996) Stroke , vol.27 , pp. 852-857
    • Krupinski, J.1    Kumar, P.2    Kumar, S.3    Kaluza, J.4
  • 39
    • 79955651800 scopus 로고    scopus 로고
    • Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation
    • Li L, Zhang H, Varrin-Doyer M, Zamvil SS, Verkman AS (2011) Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation. FASEB J 25:1556-1566.
    • (2011) FASEB J , vol.25 , pp. 1556-1566
    • Li, L.1    Zhang, H.2    Varrin-Doyer, M.3    Zamvil, S.S.4    Verkman, A.S.5
  • 40
    • 38949087309 scopus 로고    scopus 로고
    • Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo
    • Lichter-Konecki U, Mangin JM, Gordish-Dressman H, Hoffman EP, Gallo V (2008) Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo. Glia 56:365-377.
    • (2008) Glia , vol.56 , pp. 365-377
    • Lichter-Konecki, U.1    Mangin, J.M.2    Gordish-Dressman, H.3    Hoffman, E.P.4    Gallo, V.5
  • 41
    • 0026510668 scopus 로고
    • Transforming growth factor-beta 1 in the rat brain: Increase after injury and inhibition of astrocyte proliferation
    • Lindholm D, Castrén E, Kiefer R, Zafra F, Thoenen H (1992) Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol 117:395-400.
    • (1992) J Cell Biol , vol.117 , pp. 395-400
    • Lindholm, D.1    Castrén, E.2    Kiefer, R.3    Zafra, F.4    Thoenen, H.5
  • 43
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ, Gibson RM (2006) The role of inflammation in CNS injury and disease. Br J Pharmacol 147 [Suppl 1]:S232-S240.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 44
    • 0037300319 scopus 로고    scopus 로고
    • The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)
    • Mahad DJ, Ransohoff RM (2003) The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol 15:23-32.
    • (2003) Semin Immunol , vol.15 , pp. 23-32
    • Mahad, D.J.1    Ransohoff, R.M.2
  • 45
    • 49649103837 scopus 로고    scopus 로고
    • CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis
    • McCandless EE, Zhang B, Diamond MS, Klein RS (2008) CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci U S A 105:11270-11275.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11270-11275
    • McCandless, E.E.1    Zhang, B.2    Diamond, M.S.3    Klein, R.S.4
  • 47
    • 33749508895 scopus 로고    scopus 로고
    • Essential protective roles of reactive astrocytes in traumatic brain injury
    • Myer DJ, Gurkoff GG, Lee SM, Hovda DA, Sofroniew MV (2006) Essential protective roles of reactive astrocytes in traumatic brain injury. Brain 129:2761-2772.
    • (2006) Brain , vol.129 , pp. 2761-2772
    • Myer, D.J.1    Gurkoff, G.G.2    Lee, S.M.3    Hovda, D.A.4    Sofroniew, M.V.5
  • 48
    • 0037444676 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors
    • Neary JT, Kang Y, Willoughby KA, Ellis EF (2003) Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors. J Neurosci 23: 2348-2356.
    • (2003) J Neurosci , vol.23 , pp. 2348-2356
    • Neary, J.T.1    Kang, Y.2    Willoughby, K.A.3    Ellis, E.F.4
  • 52
    • 0035964833 scopus 로고    scopus 로고
    • Analysis of genes differentially expressed in astrocytes stimulated with lipopolysaccharide using cDNA arrays
    • Pang Y, Cai Z, Rhodes PG (2001) Analysis of genes differentially expressed in astrocytes stimulated with lipopolysaccharide using cDNA arrays. Brain Res 914:15-22.
    • (2001) Brain Res , vol.914 , pp. 15-22
    • Pang, Y.1    Cai, Z.2    Rhodes, P.G.3
  • 53
    • 77954653333 scopus 로고    scopus 로고
    • CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
    • Patel JR, McCandless EE, Dorsey D, Klein RS (2010) CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc Natl Acad Sci U S A 107:11062-11067.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11062-11067
    • Patel, J.R.1    McCandless, E.E.2    Dorsey, D.3    Klein, R.S.4
  • 54
    • 20344398223 scopus 로고    scopus 로고
    • Astrocyte activation and reactive gliosis
    • Pekny M, Nilsson M (2005) Astrocyte activation and reactive gliosis. Glia 50:427-434.
    • (2005) Glia , vol.50 , pp. 427-434
    • Pekny, M.1    Nilsson, M.2
  • 55
  • 56
    • 77949727731 scopus 로고    scopus 로고
    • Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro
    • Sarafian TA, Montes C, Imura T, Qi J, Coppola G, Geschwind DH, Sofroniew MV (2010) Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. PLoS One 5:e9532.
    • (2010) PLoS One , vol.5
    • Sarafian, T.A.1    Montes, C.2    Imura, T.3    Qi, J.4    Coppola, G.5    Geschwind, D.H.6    Sofroniew, M.V.7
  • 57
    • 0033638008 scopus 로고    scopus 로고
    • Signaling mechanisms of altered cellular responses in trauma, burn, and sepsis: Role of Ca2+
    • Sayeed MM (2000) Signaling mechanisms of altered cellular responses in trauma, burn, and sepsis: role of Ca2+. Arch Surg 135:1432-1442.
    • (2000) Arch Surg , vol.135 , pp. 1432-1442
    • Sayeed, M.M.1
  • 58
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: An overview of signals, mechanisms and functions
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA (2004) Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75:163-189.
    • (2004) J Leukoc Biol , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 60
    • 80055114266 scopus 로고    scopus 로고
    • Measuring near plasma membrane and global intracellular calcium dynamics in astrocytes
    • Shigetomi E, Khakh BS (2009) Measuring near plasma membrane and global intracellular calcium dynamics in astrocytes. J Vis Exp 26:pii:1142.
    • (2009) J Vis Exp 26:Pii , pp. 1142
    • Shigetomi, E.1    Khakh, B.S.2
  • 61
    • 84555172978 scopus 로고    scopus 로고
    • TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3
    • Shigetomi E, Tong X, Kwan KY, Corey DP, Khakh BS (2012) TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat Neurosci 15:70-80.
    • (2012) Nat Neurosci , vol.15 , pp. 70-80
    • Shigetomi, E.1    Tong, X.2    Kwan, K.Y.3    Corey, D.P.4    Khakh, B.S.5
  • 62
    • 35348876080 scopus 로고    scopus 로고
    • CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis
    • Sitati E, McCandless EE, Klein RS, Diamond MS (2007) CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis. J Virol 81:9801-9811.
    • (2007) J Virol , vol.81 , pp. 9801-9811
    • Sitati, E.1    McCandless, E.E.2    Klein, R.S.3    Diamond, M.S.4
  • 63
    • 4544341015 scopus 로고    scopus 로고
    • Linear Models and Empirical Bayes Methods For Assessing Differential Expression In Microarray Experiments
    • Berkeley, CA: Berkeley Electronic Press. E-book
    • Smyth GK (2004) Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. In: Statistical applications in genetics and molecular biology. Berkeley, CA: Berkeley Electronic Press. E-book available at http://www.bepress.com/sagmb/vol3/iss1/art3.
    • (2004) Statistical Applications In Genetics and Molecular Biology
    • Smyth, G.K.1
  • 64
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • Sofroniew MV (2009) Molecular dissection of reactive astrogliosis and glial scar formation. Trends Neurosci 32:638-647.
    • (2009) Trends Neurosci , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 66
    • 84855804372 scopus 로고    scopus 로고
    • Interleukin-15 biology and its therapeutic implications in cancer
    • Steel JC, Waldmann TA, Morris JC (2012) Interleukin-15 biology and its therapeutic implications in cancer. Trends Pharmacol Sci 33:35-41.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 35-41
    • Steel, J.C.1    Waldmann, T.A.2    Morris, J.C.3
  • 69
    • 0031893563 scopus 로고    scopus 로고
    • Glial calcium: Homeostasis and signaling function
    • Verkhratsky A, Orkand RK, Kettenmann H (1998) Glial calcium: homeostasis and signaling function. Physiol Rev 78:99-141.
    • (1998) Physiol Rev , vol.78 , pp. 99-141
    • Verkhratsky, A.1    Orkand, R.K.2    Kettenmann, H.3
  • 70
    • 70349103383 scopus 로고    scopus 로고
    • Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS
    • Voskuhl RR, Peterson RS, Song B, Ao Y, Morales LB, Tiwari-Woodruff S, Sofroniew MV (2009) Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. J Neurosci 29:11511-11522.
    • (2009) J Neurosci , vol.29 , pp. 11511-11522
    • Voskuhl, R.R.1    Peterson, R.S.2    Song, B.3    Ao, Y.4    Morales, L.B.5    Tiwari-Woodruff, S.6    Sofroniew, M.V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.