The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation

Free Radical Biology and Medicine

Volumn 68, Issue , 2014, Pages 268-277

  Frijhoff, Jeroen ^a   Dagnell, Markus ^a   Augsten, Martin ^a   Beltrami, Elena ^b   Giorgio, Marco ^b   Östman, Arne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Cysteine oxidation; Free radicals; Mitochondria; PDGF; Protein tyrosine phosphatase

Indexed keywords

P66SHC PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; ENZYME METABOLISM; INTRACELLULAR SIGNALING; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION;

CYSTEINE OXIDATION; FREE RADICALS; MITOCHONDRIA; PDGF; PROTEIN TYROSINE PHOSPHATASE;

ANIMALS; CELL MOVEMENT; FIBROBLASTS; FREE RADICALS; HYDROGEN PEROXIDE; MICE; MITOCHONDRIA; NIH 3T3 CELLS; OXIDATION-REDUCTION; PROTEIN TYROSINE PHOSPHATASES; REACTIVE OXYGEN SPECIES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SHC SIGNALING ADAPTOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 84892388139     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.12.022     Document Type: Article

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