Mitochondrial localization and the persistent migration of epithelial cancer cells

Biophysical Journal

Volumn 104, Issue 9, 2013, Pages 2077-2088

  Desai, Salil P ^a,b   Bhatia, Sangeeta N ^a,c   Toner, Mehmet ^a,b   Irimia, Daniel ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNM1L PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN; OPA1 PROTEIN, HUMAN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOT1 PROTEIN, HUMAN;

ARTICLE; CELL MOTION; GENETICS; HUMAN; METABOLISM; MICROTUBULE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MUTATION; NEOPLASM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; ULTRASTRUCTURE;

CELL LINE, TUMOR; CELL MOVEMENT; GTP PHOSPHOHYDROLASES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; MUTATION; NEOPLASMS, GLANDULAR AND EPITHELIAL; RHO GTP-BINDING PROTEINS;

EID: 84877290780     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2013.03.025     Document Type: Article

References (36)

1. A.J. Ridley, and M.A. Schwartz A.R. Horwitz Cell migration: integrating signals from front to back Science 302 2003 1704 1709
2. A.M. Yvon, and J.W. Walker P. Wadsworth Centrosome reorientation in wound-edge cells is cell type specific Mol. Biol. Cell 13 2002 1871 1880
3. P.M. Miller, and A.W. Folkmann I. Kaverina Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells Nat. Cell Biol. 11 2009 1069 1080
4. F. Pouthas, and P. Girard E.G. Reynaud In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum J. Cell Sci. 121 2008 2406 2414
5. A.C. Uetrecht, and J.E. Bear Golgi polarity does not correlate with speed or persistence of freely migrating fibroblasts Eur. J. Cell Biol. 88 2009 711 717
6. S. Campello, and R.A. Lacalle A. Viola Orchestration of lymphocyte chemotaxis by mitochondrial dynamics J. Exp. Med. 203 2006 2879 2886
7. M.R. Lewis, and W.H. Lewis Mitochondria in tissue culture Science 39 1914 330 333
8. P.J. Hollenbeck, and W.M. Saxton The axonal transport of mitochondria J. Cell Sci. 118 2005 5411 5419
9. R.L. Morris, and P.J. Hollenbeck Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons J. Cell Biol. 131 1995 1315 1326
10. R.L. Frederick, and J.M. Shaw Moving mitochondria: establishing distribution of an essential organelle Traffic 8 2007 1668 1675
11. E.B. Brown, and R.B. Campbell R.K. Jain In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy Nat. Med. 7 2001 864 868
12. J. Condeelis, and J.E. Segall Intravital imaging of cell movement in tumours Nat. Rev. Cancer 3 2003 921 930
13. K.L. Farina, and J.B. Wyckoff J.G. Jones Cell motility of tumor cells visualized in living intact primary tumors using green fluorescent protein Cancer Res. 58 1998 2528 2532
14. R.B. Hazan, and G.R. Phillips S.A. Aaronson Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis J. Cell Biol. 148 2000 779 790
15. L. Ma, J. Teruya-Feldstein, and R.A. Weinberg Tumour invasion and metastasis initiated by microRNA-10b in breast cancer Nature 449 2007 682 688
16. Q. Zeng, and J.M. Dong W. Hong PRL-3 and PRL-1 promote cell migration, invasion, and metastasis Cancer Res. 63 2003 2716 2722
17. D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
18. J. Calbo, and E. van Montfort A. Berns A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer Cancer Cell 19 2011 244 256
19. G.H. Heppner Tumor heterogeneity Cancer Res. 44 1984 2259 2265
20. D. Irimia, and M. Toner Spontaneous migration of cancer cells under conditions of mechanical confinement Integr. Biol. (Camb) 1 2009 506 512
21. C. Scherber, and A.J. Aranyosi D. Irimia Epithelial cell guidance by self-generated EGF gradients Integr. Biol. (Camb) 4 2012 259 269
22. R. Pankov, and Y. Endo K.M. Yamada A Rac switch regulates random versus directionally persistent cell migration J. Cell Biol. 170 2005 793 802
23. D. Irimia, and G. Charras M. Toner Polar stimulation and constrained cell migration in microfluidic channels Lab Chip 7 2007 1783 1790
24. V. Ambravaneswaran, and I.Y. Wong D. Irimia Directional decisions during neutrophil chemotaxis inside bifurcating channels Integr. Biol. (Camb) 2 2010 639 647
25. C.N. Jones, and J. Dalli D. Irimia Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions Proc. Natl. Acad. Sci. USA 109 2012 20560 20565
26. A.F. MacAskill, and J.T. Kittler Control of mitochondrial transport and localization in neurons Trends Cell Biol. 20 2010 102 112
27. A. Fransson, A. Ruusala, and P. Aspenström Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis J. Biol. Chem. 278 2003 6495 6502
28. S. Fransson, A. Ruusala, and P. Aspenström The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking Biochem. Biophys. Res. Commun. 344 2006 500 510
29. A.F. Macaskill, and J.E. Rinholm J.T. Kittler Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses Neuron 61 2009 541 555
30. M.A. del Pozo, and M. Nieto F. Sánchez-Madrid The two poles of the lymphocyte: specialized cell compartments for migration and recruitment Cell Adhes. Commun. 6 1998 125 133
31. G.W. Luxton, and G.G. Gundersen Orientation and function of the nuclear-centrosomal axis during cell migration Curr. Opin. Cell Biol. 23 2011 579 588
32. I. Nemere, A. Kupfer, and S.J. Singer Reorientation of the Golgi apparatus and the microtubule-organizing center inside macrophages subjected to a chemotactic gradient Cell Motil. 5 1985 17 29
33. J.H. Evans, and J.J. Falke Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages Proc. Natl. Acad. Sci. USA 104 2007 16176 16181
34. M. Yi, D. Weaver, and G. Hajnóczky Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit J. Cell Biol. 167 2004 661 672
35. A.G. Bick, S.E. Calvo, and V.K. Mootha Evolutionary diversity of the mitochondrial calcium uniporter Science 336 2012 886
36. A. Wolfer, and B.S. Wittner S. Ramaswamy MYC regulation of a "poor-prognosis" metastatic cancer cell state Proc. Natl. Acad. Sci. USA 107 2010 3698 3703