메뉴 건너뛰기




Volumn 27, Issue 2, 2014, Pages 117-128

B-cell regulation and its application to transplantation

Author keywords

alloantibody; antibody mediated rejection; B cells; BAFF; regulatory B cells; rituximab

Indexed keywords

B CELL ACTIVATING FACTOR; CD22 ANTIGEN; CD40 LIGAND; FC RECEPTOR IIB; INTERLEUKIN 10;

EID: 84892364758     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12160     Document Type: Review
Times cited : (33)

References (133)
  • 1
    • 0023143381 scopus 로고
    • The B cell is the initiating antigen-presenting cell in peripheral lymph nodes
    • Janeway CA Jr, Ron J, Katz ME,. The B cell is the initiating antigen-presenting cell in peripheral lymph nodes. J Immunol 1987; 138: 1051.
    • (1987) J Immunol , vol.138 , pp. 1051
    • Janeway, Jr.C.A.1    Ron, J.2    Katz, M.E.3
  • 2
    • 0023223175 scopus 로고
    • T cell priming in vivo: A major role for B cells in presenting antigen to T cells in lymph nodes
    • Ron Y, Sprent J,. T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol 1987; 138: 2848.
    • (1987) J Immunol , vol.138 , pp. 2848
    • Ron, Y.1    Sprent, J.2
  • 3
    • 0032489912 scopus 로고    scopus 로고
    • The sequential role of lymphotoxin and B cells in the development of splenic follicles
    • Gonzalez M, Mackay F, Browning JL, Kosco-Vilbois MH, Noelle RJ,. The sequential role of lymphotoxin and B cells in the development of splenic follicles. J Exp Med 1998; 187: 997.
    • (1998) J Exp Med , vol.187 , pp. 997
    • Gonzalez, M.1    Mackay, F.2    Browning, J.L.3    Kosco-Vilbois, M.H.4    Noelle, R.J.5
  • 5
    • 0035803465 scopus 로고    scopus 로고
    • Splenic T zone development is B cell dependent
    • Ngo VN, Cornall RJ, Cyster JG,. Splenic T zone development is B cell dependent. J Exp Med 2001; 194: 1649.
    • (2001) J Exp Med , vol.194 , pp. 1649
    • Ngo, V.N.1    Cornall, R.J.2    Cyster, J.G.3
  • 6
    • 84856655455 scopus 로고    scopus 로고
    • Innate response activator B cells protect against microbial sepsis
    • Rauch PJ, Chudnovskiy A, Robbins CS, et al,. Innate response activator B cells protect against microbial sepsis. Science 2012; 335: 597.
    • (2012) Science , vol.335 , pp. 597
    • Rauch, P.J.1    Chudnovskiy, A.2    Robbins, C.S.3
  • 7
    • 79959823291 scopus 로고    scopus 로고
    • Targeting B cells and antibody in transplantation
    • Clatworthy MR,. Targeting B cells and antibody in transplantation. Am J Transplant 2011; 11: 1359.
    • (2011) Am J Transplant , vol.11 , pp. 1359
    • Clatworthy, M.R.1
  • 8
    • 84871722009 scopus 로고    scopus 로고
    • Five-year outcomes in living donor kidney transplants with a positive crossmatch
    • Bentall A, Cornell LD, Gloor JM, et al,. Five-year outcomes in living donor kidney transplants with a positive crossmatch. Am J Transplant 2013; 13: 76.
    • (2013) Am J Transplant , vol.13 , pp. 76
    • Bentall, A.1    Cornell, L.D.2    Gloor, J.M.3
  • 10
    • 84861751725 scopus 로고    scopus 로고
    • The impact of donor-specific anti-HLA antibodies on late kidney allograft failure
    • Loupy A, Hill GS, Jordan SC,. The impact of donor-specific anti-HLA antibodies on late kidney allograft failure. Nat Rev Nephrol 2012; 8: 348.
    • (2012) Nat Rev Nephrol , vol.8 , pp. 348
    • Loupy, A.1    Hill, G.S.2    Jordan, S.C.3
  • 11
    • 80053307061 scopus 로고    scopus 로고
    • Revisiting traditional risk factors for rejection and graft loss after kidney transplantation
    • Dunn TB, Noreen H, Gillingham K, et al,. Revisiting traditional risk factors for rejection and graft loss after kidney transplantation. Am J Transplant 2011; 11: 2132.
    • (2011) Am J Transplant , vol.11 , pp. 2132
    • Dunn, T.B.1    Noreen, H.2    Gillingham, K.3
  • 12
    • 0038679758 scopus 로고    scopus 로고
    • Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling
    • Sarwal M, Chua MS, Kambham N, et al,. Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl J Med 2003; 349: 125.
    • (2003) N Engl J Med , vol.349 , pp. 125
    • Sarwal, M.1    Chua, M.S.2    Kambham, N.3
  • 13
    • 27844510762 scopus 로고    scopus 로고
    • Association of CD20 + infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts
    • Hippen BE, DeMattos A, Cook WJ, Kew CE 2nd, Gaston RS,. Association of CD20 + infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts. Am J Transplant 2005; 5: 2248.
    • (2005) Am J Transplant , vol.5 , pp. 2248
    • Hippen, B.E.1    Demattos, A.2    Cook, W.J.3    Kew II, C.E.4    Gaston, R.S.5
  • 15
    • 75749087574 scopus 로고    scopus 로고
    • B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer
    • DiLillo DJ, Matsushita T, Tedder TF,. B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer. Ann N Y Acad Sci 2010; 1183: 38.
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 38
    • Dilillo, D.J.1    Matsushita, T.2    Tedder, T.F.3
  • 16
    • 84859385739 scopus 로고    scopus 로고
    • Immune regulatory function of B cells
    • Mauri C, Bosma A,. Immune regulatory function of B cells. Annu Rev Immunol 2012; 30: 221.
    • (2012) Annu Rev Immunol , vol.30 , pp. 221
    • Mauri, C.1    Bosma, A.2
  • 17
    • 77955665719 scopus 로고    scopus 로고
    • Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype
    • Pallier A, Hillion S, Danger R, et al,. Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype. Kidney Int 2010; 78: 503.
    • (2010) Kidney Int , vol.78 , pp. 503
    • Pallier, A.1    Hillion, S.2    Danger, R.3
  • 18
    • 77953178765 scopus 로고    scopus 로고
    • Identification of a B cell signature associated with renal transplant tolerance in humans
    • Newell KA, Asare A, Kirk AD, et al,. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 2010; 120: 1836.
    • (2010) J Clin Invest , vol.120 , pp. 1836
    • Newell, K.A.1    Asare, A.2    Kirk, A.D.3
  • 19
    • 84872078503 scopus 로고    scopus 로고
    • B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients
    • Viklicky O, Krystufkova E, Brabcova I, et al,. B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients. Transplantation 2013; 95: 148.
    • (2013) Transplantation , vol.95 , pp. 148
    • Viklicky, O.1    Krystufkova, E.2    Brabcova, I.3
  • 20
    • 78651509914 scopus 로고    scopus 로고
    • Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20 + CD27 + CD43 + CD70
    • Griffin DO, Holodick NE, Rothstein TL,. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20 + CD27 + CD43 + CD70. J Exp Med 2011; 208: 67.
    • (2011) J Exp Med , vol.208 , pp. 67
    • Griffin, D.O.1    Holodick, N.E.2    Rothstein, T.L.3
  • 21
    • 0035314006 scopus 로고    scopus 로고
    • B1 cells: Similarities and differences with other B cell subsets
    • Martin F, Kearney JF,. B1 cells: similarities and differences with other B cell subsets. Curr Opin Immunol 2001; 13: 195.
    • (2001) Curr Opin Immunol , vol.13 , pp. 195
    • Martin, F.1    Kearney, J.F.2
  • 22
    • 84860879274 scopus 로고    scopus 로고
    • Pivotal advance: Peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4 + T cells
    • Parra D, Rieger AM, Li J, et al,. Pivotal advance: peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4 + T cells. J Leukoc Biol 2012; 91: 525.
    • (2012) J Leukoc Biol , vol.91 , pp. 525
    • Parra, D.1    Rieger, A.M.2    Li, J.3
  • 23
    • 80053574700 scopus 로고    scopus 로고
    • B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions
    • Kyaw T, Tay C, Krishnamurthi S, et al,. B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions. Circ Res 2011; 109: 830.
    • (2011) Circ Res , vol.109 , pp. 830
    • Kyaw, T.1    Tay, C.2    Krishnamurthi, S.3
  • 24
    • 0029127069 scopus 로고
    • Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells
    • Dunn-Walters DK, Isaacson PG, Spencer J,. Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J Exp Med 1995; 182: 559.
    • (1995) J Exp Med , vol.182 , pp. 559
    • Dunn-Walters, D.K.1    Isaacson, P.G.2    Spencer, J.3
  • 25
    • 74649083783 scopus 로고    scopus 로고
    • CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients
    • Blair PA, Norena LY, Flores-Borja F, et al,. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. Immunity 2010; 32: 129.
    • (2010) Immunity , vol.32 , pp. 129
    • Blair, P.A.1    Norena, L.Y.2    Flores-Borja, F.3
  • 26
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
    • Iwata Y, Matsushita T, Horikawa M, et al,. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood 2011; 117: 530.
    • (2011) Blood , vol.117 , pp. 530
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3
  • 27
    • 80052382391 scopus 로고    scopus 로고
    • Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
    • Ding Q, Yeung M, Camirand G, et al,. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest 2011; 121: 3645.
    • (2011) J Clin Invest , vol.121 , pp. 3645
    • Ding, Q.1    Yeung, M.2    Camirand, G.3
  • 28
    • 84892365352 scopus 로고    scopus 로고
    • Human regulatory B cells (BRegs) are Characterised by both IL-10 and TNF-α expression and are reduced in numbers with altered function in renal transplant recipients with immunological graft injury
    • Cherukuri A, Salama A, Carter C, Clark B, Rothstein D, Baker R., Human regulatory B cells (BRegs) are Characterised by both IL-10 and TNF-α expression and are reduced in numbers with altered function in renal transplant recipients with immunological graft injury. Am J Transplant 2013; 13: 229.
    • (2013) Am J Transplant , vol.13 , pp. 229
    • Cherukuri, A.1    Salama, A.2    Carter, C.3    Clark, B.4    Rothstein, D.5    Baker, R.6
  • 29
    • 0026688237 scopus 로고
    • The B cell antigen receptor complex: Association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors
    • Clark MR, Campbell KS, Kazlauskas A, et al,. The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors. Science 1992; 258: 123.
    • (1992) Science , vol.258 , pp. 123
    • Clark, M.R.1    Campbell, K.S.2    Kazlauskas, A.3
  • 30
    • 0027290883 scopus 로고
    • Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta
    • Sanchez M, Misulovin Z, Burkhardt AL, et al,. Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta. J Exp Med 1993; 178: 1049.
    • (1993) J Exp Med , vol.178 , pp. 1049
    • Sanchez, M.1    Misulovin, Z.2    Burkhardt, A.L.3
  • 31
    • 0025323932 scopus 로고
    • Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor
    • Gold MR, Law DA, DeFranco AL,. Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor. Nature 1990; 345: 810.
    • (1990) Nature , vol.345 , pp. 810
    • Gold, M.R.1    Law, D.A.2    Defranco, A.L.3
  • 32
    • 0026587743 scopus 로고
    • CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
    • Carter RH, Fearon DT,. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 1992; 256: 105.
    • (1992) Science , vol.256 , pp. 105
    • Carter, R.H.1    Fearon, D.T.2
  • 33
    • 34548599933 scopus 로고    scopus 로고
    • Complement receptors CD21 and CD35 in humoral immunity
    • Roozendaal R, Carroll MC,. Complement receptors CD21 and CD35 in humoral immunity. Immunol Rev 2007; 219: 157.
    • (2007) Immunol Rev , vol.219 , pp. 157
    • Roozendaal, R.1    Carroll, M.C.2
  • 34
    • 77954684486 scopus 로고    scopus 로고
    • Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones
    • Isnardi I, Ng YS, Menard L, et al,. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood 2010; 115: 5026.
    • (2010) Blood , vol.115 , pp. 5026
    • Isnardi, I.1    Ng, Y.S.2    Menard, L.3
  • 35
    • 34247622766 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity in B-cell activation and antibody responses
    • Lanzavecchia A, Sallusto F,. Toll-like receptors and innate immunity in B-cell activation and antibody responses. Curr Opin Immunol 2007; 19: 268.
    • (2007) Curr Opin Immunol , vol.19 , pp. 268
    • Lanzavecchia, A.1    Sallusto, F.2
  • 36
    • 27844541797 scopus 로고    scopus 로고
    • Control of B-cell responses by Toll-like receptors
    • Pasare C, Medzhitov R,. Control of B-cell responses by Toll-like receptors. Nature 2005; 438: 364.
    • (2005) Nature , vol.438 , pp. 364
    • Pasare, C.1    Medzhitov, R.2
  • 37
    • 55749115444 scopus 로고    scopus 로고
    • BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact
    • Scholz JL, Crowley JE, Tomayko MM, et al,. BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc Natl Acad Sci USA 2008; 105: 15517.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15517
    • Scholz, J.L.1    Crowley, J.E.2    Tomayko, M.M.3
  • 38
    • 77956989585 scopus 로고    scopus 로고
    • B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation
    • Parsons RF, Vivek K, Redfield RR 3rd, et al,. B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation. Transplant Rev (Orlando) 2010; 24: 207.
    • (2010) Transplant Rev (Orlando) , vol.24 , pp. 207
    • Parsons, R.F.1    Vivek, K.2    Redfield III, R.R.3
  • 39
    • 34547772125 scopus 로고    scopus 로고
    • BAFF and MyD88 signals promote a lupuslike disease independent of T cells
    • Groom JR, Fletcher CA, Walters SN, et al,. BAFF and MyD88 signals promote a lupuslike disease independent of T cells. J Exp Med 2007; 204: 1959.
    • (2007) J Exp Med , vol.204 , pp. 1959
    • Groom, J.R.1    Fletcher, C.A.2    Walters, S.N.3
  • 40
    • 0025951891 scopus 로고
    • Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
    • Liu YJ, Zhang J, Lane PJ, Chan EY, MacLennan IC,. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur J Immunol 1991; 21: 2951.
    • (1991) Eur J Immunol , vol.21 , pp. 2951
    • Liu, Y.J.1    Zhang, J.2    Lane, P.J.3    Chan, E.Y.4    Maclennan, I.C.5
  • 41
    • 0035942781 scopus 로고    scopus 로고
    • B cells acquire antigen from target cells after synapse formation
    • Batista FD, Iber D, Neuberger MS,. B cells acquire antigen from target cells after synapse formation. Nature 2001; 411: 489.
    • (2001) Nature , vol.411 , pp. 489
    • Batista, F.D.1    Iber, D.2    Neuberger, M.S.3
  • 42
    • 77950070632 scopus 로고    scopus 로고
    • Effector and regulatory B cells: Modulators of CD4(+) T cell immunity
    • Lund FE, Randall TD,. Effector and regulatory B cells: modulators of CD4(+) T cell immunity. Nat Rev Immunol 2010; 10: 236.
    • (2010) Nat Rev Immunol , vol.10 , pp. 236
    • Lund, F.E.1    Randall, T.D.2
  • 43
    • 33751556349 scopus 로고    scopus 로고
    • B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection
    • Noorchashm H, Reed AJ, Rostami SY, et al,. B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection. J Immunol 2006; 177: 7715.
    • (2006) J Immunol , vol.177 , pp. 7715
    • Noorchashm, H.1    Reed, A.J.2    Rostami, S.Y.3
  • 45
    • 0026670190 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
    • Jacob J, Kelsoe G,. In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. J Exp Med 1992; 176: 679.
    • (1992) J Exp Med , vol.176 , pp. 679
    • Jacob, J.1    Kelsoe, G.2
  • 46
    • 79960342424 scopus 로고    scopus 로고
    • B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
    • Lee SK, Rigby RJ, Zotos D, et al,. B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. J Exp Med 2011; 208: 1377.
    • (2011) J Exp Med , vol.208 , pp. 1377
    • Lee, S.K.1    Rigby, R.J.2    Zotos, D.3
  • 47
    • 18944406639 scopus 로고    scopus 로고
    • Visualizing the onset and evolution of an autoantibody response in systemic autoimmunity
    • William J, Euler C, Leadbetter E, Marshak-Rothstein A, Shlomchik MJ,. Visualizing the onset and evolution of an autoantibody response in systemic autoimmunity. J Immunol 2005; 174: 6872.
    • (2005) J Immunol , vol.174 , pp. 6872
    • William, J.1    Euler, C.2    Leadbetter, E.3    Marshak-Rothstein, A.4    Shlomchik, M.J.5
  • 49
    • 77955898582 scopus 로고    scopus 로고
    • T cells and follicular dendritic cells in germinal center B-cell formation and selection
    • Vinuesa CG, Linterman MA, Goodnow CC, Randall KL,. T cells and follicular dendritic cells in germinal center B-cell formation and selection. Immunol Rev 2010; 237: 72.
    • (2010) Immunol Rev , vol.237 , pp. 72
    • Vinuesa, C.G.1    Linterman, M.A.2    Goodnow, C.C.3    Randall, K.L.4
  • 50
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S,. Follicular helper CD4 T cells (TFH). Annu Rev Immunol 2011; 29: 621.
    • (2011) Annu Rev Immunol , vol.29 , pp. 621
    • Crotty, S.1
  • 51
    • 26844581521 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic rejection: Evidence for a local humoral alloimmune response
    • Thaunat O, Field AC, Dai J, et al,. Lymphoid neogenesis in chronic rejection: evidence for a local humoral alloimmune response. Proc Natl Acad Sci USA 2005; 102: 14723.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14723
    • Thaunat, O.1    Field, A.C.2    Dai, J.3
  • 52
    • 10744229023 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates
    • Kerjaschki D, Regele HM, Moosberger I, et al,. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J Am Soc Nephrol 2004; 15: 603.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 603
    • Kerjaschki, D.1    Regele, H.M.2    Moosberger, I.3
  • 55
    • 0037342154 scopus 로고    scopus 로고
    • B cell inhibitory receptors and autoimmunity
    • Pritchard NR, Smith KG,. B cell inhibitory receptors and autoimmunity. Immunology 2003; 108: 263.
    • (2003) Immunology , vol.108 , pp. 263
    • Pritchard, N.R.1    Smith, K.G.2
  • 56
    • 77951610700 scopus 로고    scopus 로고
    • FcgammaRIIB in autoimmunity and infection: Evolutionary and therapeutic implications
    • Smith KGC, Clatworthy MR,. FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications. Nat Rev Immunol 2010; 10: 328.
    • (2010) Nat Rev Immunol , vol.10 , pp. 328
    • Smith, K.G.C.1    Clatworthy, M.R.2
  • 57
    • 33947575824 scopus 로고    scopus 로고
    • FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis
    • Xiang Z, Cutler AJ, Brownlie RJ, et al,. FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis. Nat Immunol 2007; 8: 419.
    • (2007) Nat Immunol , vol.8 , pp. 419
    • Xiang, Z.1    Cutler, A.J.2    Brownlie, R.J.3
  • 58
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    • Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV,. Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 1996; 379: 346.
    • (1996) Nature , vol.379 , pp. 346
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 59
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
    • Bolland S, Ravetch JV,. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity 2000; 13: 277.
    • (2000) Immunity , vol.13 , pp. 277
    • Bolland, S.1    Ravetch, J.V.2
  • 60
    • 1542313883 scopus 로고    scopus 로고
    • FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis
    • Clatworthy MR, Smith KG,. FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis. J Exp Med 2004; 199: 717.
    • (2004) J Exp Med , vol.199 , pp. 717
    • Clatworthy, M.R.1    Smith, K.G.2
  • 61
    • 34249736602 scopus 로고    scopus 로고
    • Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria
    • Clatworthy MR, Willcocks L, Urban B, et al,. Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria. Proc Natl Acad Sci USA 2007; 104: 7169.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7169
    • Clatworthy, M.R.1    Willcocks, L.2    Urban, B.3
  • 62
    • 42249096407 scopus 로고    scopus 로고
    • Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb
    • Brownlie RJ, Lawlor KE, Niederer HA, et al,. Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb J Exp Med 2008; 205: 883.
    • (2008) J Exp Med , vol.205 , pp. 883
    • Brownlie, R.J.1    Lawlor, K.E.2    Niederer, H.A.3
  • 63
    • 27144549658 scopus 로고    scopus 로고
    • Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts
    • Floto RA, Clatworthy MR, Heilbronn KR, et al,. Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat Med 2005; 11: 1056.
    • (2005) Nat Med , vol.11 , pp. 1056
    • Floto, R.A.1    Clatworthy, M.R.2    Heilbronn, K.R.3
  • 64
    • 26444593959 scopus 로고    scopus 로고
    • FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling
    • Kono H, Kyogoku C, Suzuki T, et al,. FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum Mol Genet 2005; 14: 2881.
    • (2005) Hum Mol Genet , vol.14 , pp. 2881
    • Kono, H.1    Kyogoku, C.2    Suzuki, T.3
  • 65
    • 77951572775 scopus 로고    scopus 로고
    • A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
    • Willcocks LC, Carr EJ, Niederer HA, et al,. A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus. Proc Natl Acad Sci USA 2010; 107: 7881.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7881
    • Willcocks, L.C.1    Carr, E.J.2    Niederer, H.A.3
  • 66
    • 67649792047 scopus 로고    scopus 로고
    • CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions
    • Nitschke L,. CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions. Immunol Rev 2009; 230: 128.
    • (2009) Immunol Rev , vol.230 , pp. 128
    • Nitschke, L.1
  • 67
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe TL, Williams GT, Batista FD, Neuberger MS,. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 1999; 189: 1307.
    • (1999) J Exp Med , vol.189 , pp. 1307
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4
  • 69
    • 84859266862 scopus 로고    scopus 로고
    • The state of therapy for removal of alloantibody producing plasma cells in transplantation
    • Everly MJ, Terasaki PI,. The state of therapy for removal of alloantibody producing plasma cells in transplantation. Semin Immunol 2012; 24: 143.
    • (2012) Semin Immunol , vol.24 , pp. 143
    • Everly, M.J.1    Terasaki, P.I.2
  • 70
    • 58049206825 scopus 로고    scopus 로고
    • The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection
    • Locke JE, Magro CM, Singer AL, et al,. The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection. Am J Transplant 2009; 9: 231.
    • (2009) Am J Transplant , vol.9 , pp. 231
    • Locke, J.E.1    Magro, C.M.2    Singer, A.L.3
  • 71
    • 77956133521 scopus 로고    scopus 로고
    • Eculizumab, bortezomib and kidney paired donation facilitate transplantation of a highly sensitized patient without vascular access
    • Lonze BE, Dagher NN, Simpkins CE, et al,. Eculizumab, bortezomib and kidney paired donation facilitate transplantation of a highly sensitized patient without vascular access. Am J Transplant 2010; 10: 2154.
    • (2010) Am J Transplant , vol.10 , pp. 2154
    • Lonze, B.E.1    Dagher, N.N.2    Simpkins, C.E.3
  • 72
    • 70349349365 scopus 로고    scopus 로고
    • Prevention of acute humoral rejection with C5 inhibition
    • [2009 ATC abstract 178].
    • Stegall MD, Diwan TS, Burns JM,. Prevention of acute humoral rejection with C5 inhibition [2009 ATC abstract 178]. Am J Transplant 2009; 9: 241.
    • (2009) Am J Transplant , vol.9 , pp. 241
    • Stegall, M.D.1    Diwan, T.S.2    Burns, J.M.3
  • 73
    • 79960046406 scopus 로고    scopus 로고
    • Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway
    • Anthony RM, Kobayashi T, Wermeling F, Ravetch JV,. Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. Nature 2011; 475: 110.
    • (2011) Nature , vol.475 , pp. 110
    • Anthony, R.M.1    Kobayashi, T.2    Wermeling, F.3    Ravetch, J.V.4
  • 74
    • 84875410765 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy: How does IgG modulate the immune system?
    • Schwab I, Nimmerjahn F,. Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat Rev Immunol 2013; 13: 176.
    • (2013) Nat Rev Immunol , vol.13 , pp. 176
    • Schwab, I.1    Nimmerjahn, F.2
  • 76
    • 84878519724 scopus 로고    scopus 로고
    • A single dose of rituximab does not deplete B cells in secondary lymphoid organs but alters phenotype and function
    • Kamburova EG, Koenen HJ, Borgman KJ, Ten Berge IJ, Joosten I, Hilbrands LB,. A single dose of rituximab does not deplete B cells in secondary lymphoid organs but alters phenotype and function. Am J Transplant 2013; 13: 1503.
    • (2013) Am J Transplant , vol.13 , pp. 1503
    • Kamburova, E.G.1    Koenen, H.J.2    Borgman, K.J.3    Ten Berge, I.J.4    Joosten, I.5    Hilbrands, L.B.6
  • 77
    • 67649592390 scopus 로고    scopus 로고
    • Rituximab and intravenous immunoglobulin treatment of chronic antibody-mediated kidney allograft rejection
    • Fehr T, Rusi B, Fischer A, Hopfer H, Wuthrich RP, Gaspert A,. Rituximab and intravenous immunoglobulin treatment of chronic antibody-mediated kidney allograft rejection. Transplantation 2009; 87: 1837.
    • (2009) Transplantation , vol.87 , pp. 1837
    • Fehr, T.1    Rusi, B.2    Fischer, A.3    Hopfer, H.4    Wuthrich, R.P.5    Gaspert, A.6
  • 78
    • 77951823581 scopus 로고    scopus 로고
    • Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation
    • Vo AA, Peng A, Toyoda M, et al,. Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation. Transplantation 2010; 89: 1095.
    • (2010) Transplantation , vol.89 , pp. 1095
    • Vo, A.A.1    Peng, A.2    Toyoda, M.3
  • 79
    • 33645279816 scopus 로고    scopus 로고
    • ABO-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab: A single center experience
    • Donauer J, Wilpert J, Geyer M, et al,. ABO-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab: a single center experience. Xenotransplantation 2006; 13: 108.
    • (2006) Xenotransplantation , vol.13 , pp. 108
    • Donauer, J.1    Wilpert, J.2    Geyer, M.3
  • 80
    • 34248396788 scopus 로고    scopus 로고
    • Implementation of a Protocol for ABO-incompatible kidney transplantation-a three-center experience with 60 consecutive transplantations
    • Tyden G, Donauer J, Wadstrom J, et al,. Implementation of a Protocol for ABO-incompatible kidney transplantation-a three-center experience with 60 consecutive transplantations. Transplantation 2007; 83: 1153.
    • (2007) Transplantation , vol.83 , pp. 1153
    • Tyden, G.1    Donauer, J.2    Wadstrom, J.3
  • 81
    • 56749133302 scopus 로고    scopus 로고
    • Japan's experience with living-donor kidney transplantation across ABO barriers
    • Ichimaru N, Takahara S,. Japan's experience with living-donor kidney transplantation across ABO barriers. Nature Clinical Practice Nephrology 2008; 4: 682.
    • (2008) Nature Clinical Practice Nephrology , vol.4 , pp. 682
    • Ichimaru, N.1    Takahara, S.2
  • 82
    • 83155192617 scopus 로고    scopus 로고
    • Infectious complications in kidney-transplant recipients desensitized with rituximab and intravenous immunoglobulin
    • Kahwaji J, Sinha A, Toyoda M, et al,. Infectious complications in kidney-transplant recipients desensitized with rituximab and intravenous immunoglobulin. Clinical Journal of the American Society of Nephrology: CJASN 2011; 6: 2894.
    • (2011) Clinical Journal of the American Society of Nephrology: CJASN , vol.6 , pp. 2894
    • Kahwaji, J.1    Sinha, A.2    Toyoda, M.3
  • 83
    • 84892366012 scopus 로고    scopus 로고
    • One year results of the effects of Rituximab on acute humoral rejection in renal transplantation: RITUX ERAH, a multicentre randomized placebo controlled trial
    • Sautenet B, Blancho G, Buchler M, et al,. One year results of the effects of Rituximab on acute humoral rejection in renal transplantation: RITUX ERAH, a multicentre randomized placebo controlled trial. Am J Transplant 2013; 13: 112.
    • (2013) Am J Transplant , vol.13 , pp. 112
    • Sautenet, B.1    Blancho, G.2    Buchler, M.3
  • 84
    • 77953360290 scopus 로고    scopus 로고
    • Combined posttransplant prophylactic IVIg/anti-CD 20/plasmapheresis in kidney recipients with preformed donor-specific antibodies: A pilot study
    • Loupy A, Suberbielle-Boissel C, Zuber J, et al,. Combined posttransplant prophylactic IVIg/anti-CD 20/plasmapheresis in kidney recipients with preformed donor-specific antibodies: a pilot study. Transplantation 2010; 89: 1403.
    • (2010) Transplantation , vol.89 , pp. 1403
    • Loupy, A.1    Suberbielle-Boissel, C.2    Zuber, J.3
  • 85
    • 84856436154 scopus 로고    scopus 로고
    • Chronic antibody-mediated rejection is reduced by targeting B-cell immunity during an introductory period
    • Kohei N, Hirai T, Omoto K, Ishida H, Tanabe K,. Chronic antibody-mediated rejection is reduced by targeting B-cell immunity during an introductory period. Am J Transplant 2012; 12: 469.
    • (2012) Am J Transplant , vol.12 , pp. 469
    • Kohei, N.1    Hirai, T.2    Omoto, K.3    Ishida, H.4    Tanabe, K.5
  • 86
    • 67649607453 scopus 로고    scopus 로고
    • A randomized, doubleblind, placebo-controlled, study of single-dose rituximab as induction in renal transplantation
    • Tyden G, Genberg H, Tollemar J, et al,. A randomized, doubleblind, placebo-controlled, study of single-dose rituximab as induction in renal transplantation. Transplantation 2009; 87: 1325.
    • (2009) Transplantation , vol.87 , pp. 1325
    • Tyden, G.1    Genberg, H.2    Tollemar, J.3
  • 87
    • 67449146920 scopus 로고    scopus 로고
    • B-cell-depleting induction therapy and acute cellular rejection
    • Clatworthy MR, Watson CJ, Plotnek G, et al,. B-cell-depleting induction therapy and acute cellular rejection. N Engl J Med 2009; 360: 2683.
    • (2009) N Engl J Med , vol.360 , pp. 2683
    • Clatworthy, M.R.1    Watson, C.J.2    Plotnek, G.3
  • 89
    • 84864655397 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of single dose rituximab as induction in renal transplantation: A 3-year follow-up
    • Tyden G, Ekberg H, Tufveson G, Mjornstedt L,. A randomized, double-blind, placebo-controlled study of single dose rituximab as induction in renal transplantation: a 3-year follow-up. Transplantation 2012; 94: e21.
    • (2012) Transplantation , vol.94
    • Tyden, G.1    Ekberg, H.2    Tufveson, G.3    Mjornstedt, L.4
  • 90
    • 79951838633 scopus 로고    scopus 로고
    • B lymphocytes differentially influence acute and chronic allograft rejection in mice
    • Dilillo DJ, Griffiths R, Seshan SV, et al,. B lymphocytes differentially influence acute and chronic allograft rejection in mice. J Immunol 2011; 186: 2643.
    • (2011) J Immunol , vol.186 , pp. 2643
    • Dilillo, D.J.1    Griffiths, R.2    Seshan, S.V.3
  • 91
    • 65249176956 scopus 로고    scopus 로고
    • Rituximab-induced vasculitis: A case report and review of the medical published work
    • Kim MJ, Kim HO, Kim HY, Park YM,. Rituximab-induced vasculitis: a case report and review of the medical published work. J Dermatol 2009; 36: 284.
    • (2009) J Dermatol , vol.36 , pp. 284
    • Kim, M.J.1    Kim, H.O.2    Kim, H.Y.3    Park, Y.M.4
  • 92
    • 77955386129 scopus 로고    scopus 로고
    • Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study
    • Ostergaard M, Baslund B, Rigby W, et al,. Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: results of a randomized, double-blind, placebo-controlled, phase I/II study. Arthritis Rheum 2010; 62: 2227.
    • (2010) Arthritis Rheum , vol.62 , pp. 2227
    • Ostergaard, M.1    Baslund, B.2    Rigby, W.3
  • 93
    • 70349973753 scopus 로고    scopus 로고
    • CD19: A promising B cell target for rheumatoid arthritis
    • Tedder TF,. CD19: a promising B cell target for rheumatoid arthritis. Nat Rev Rheumatol 2009; 5: 572.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 572
    • Tedder, T.F.1
  • 94
    • 78049395507 scopus 로고    scopus 로고
    • Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 humanized antibodies correlate with enhanced toxicity to B-cell lymphomas and leukemias
    • Gupta P, Goldenberg DM, Rossi EA, Chang CH,. Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 humanized antibodies correlate with enhanced toxicity to B-cell lymphomas and leukemias. Blood 2010; 116: 3258.
    • (2010) Blood , vol.116 , pp. 3258
    • Gupta, P.1    Goldenberg, D.M.2    Rossi, E.A.3    Chang, C.H.4
  • 95
    • 77953435950 scopus 로고    scopus 로고
    • Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases
    • Vallera DA, Oh S, Chen H, Shu Y, Frankel AE,. Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases. Mol Cancer Ther 2010; 9: 1872.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1872
    • Vallera, D.A.1    Oh, S.2    Chen, H.3    Shu, Y.4    Frankel, A.E.5
  • 96
    • 7244223338 scopus 로고    scopus 로고
    • BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses
    • Ye Q, Wang L, Wells AD, et al,. BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol 2004; 34: 2750.
    • (2004) Eur J Immunol , vol.34 , pp. 2750
    • Ye, Q.1    Wang, L.2    Wells, A.D.3
  • 97
    • 84859270711 scopus 로고    scopus 로고
    • Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator BLyS/BAFF
    • Parsons RF, Yu M, Vivek K, et al,. Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator BLyS/BAFF. Transplantation 2012; 93: 676.
    • (2012) Transplantation , vol.93 , pp. 676
    • Parsons, R.F.1    Yu, M.2    Vivek, K.3
  • 98
    • 60649087371 scopus 로고    scopus 로고
    • The expression of B-cell activating factor belonging to tumor necrosis factor superfamily (BAFF) significantly correlated with C4D in kidney allograft rejection
    • Xu H, He X, Sun J, Shi D, Zhu Y, Zhang X,. The expression of B-cell activating factor belonging to tumor necrosis factor superfamily (BAFF) significantly correlated with C4D in kidney allograft rejection. Transplant Proc 2009; 41: 112.
    • (2009) Transplant Proc , vol.41 , pp. 112
    • Xu, H.1    He, X.2    Sun, J.3    Shi, D.4    Zhu, Y.5    Zhang, X.6
  • 99
    • 67249161386 scopus 로고    scopus 로고
    • Abnormal high expression of B-cell activating factor belonging to the TNF superfamily (BAFF) associated with long-term outcome in kidney transplant recipients
    • Xu H, He X, Liu Q, et al,. Abnormal high expression of B-cell activating factor belonging to the TNF superfamily (BAFF) associated with long-term outcome in kidney transplant recipients. Transplant Proc 2009; 41: 1552.
    • (2009) Transplant Proc , vol.41 , pp. 1552
    • Xu, H.1    He, X.2    Liu, Q.3
  • 100
    • 47049126989 scopus 로고    scopus 로고
    • B cell survival in intragraft tertiary lymphoid organs after rituximab therapy
    • Thaunat O, Patey N, Gautreau C, et al,. B cell survival in intragraft tertiary lymphoid organs after rituximab therapy. Transplantation 2008; 85: 1648.
    • (2008) Transplantation , vol.85 , pp. 1648
    • Thaunat, O.1    Patey, N.2    Gautreau, C.3
  • 101
    • 84867097567 scopus 로고    scopus 로고
    • BAFF and BAFF-R levels are associated with risk of long-term kidney graft dysfunction and development of donor-specific antibodies
    • Thibault-Espitia A, Foucher Y, Danger R, et al,. BAFF and BAFF-R levels are associated with risk of long-term kidney graft dysfunction and development of donor-specific antibodies. Am J Transplant 2012; 12: 2754.
    • (2012) Am J Transplant , vol.12 , pp. 2754
    • Thibault-Espitia, A.1    Foucher, Y.2    Danger, R.3
  • 102
    • 84883449664 scopus 로고    scopus 로고
    • Elevated pre-transplant soluble BAFF is associated with an increased risk of acute antibody-mediated rejection
    • [Epub ahead of print].
    • Banham G, Prezzi D, Harford S, et al,. Elevated pre-transplant soluble BAFF is associated with an increased risk of acute antibody-mediated rejection. Transplantation 2013. [Epub ahead of print].
    • (2013) Transplantation
    • Banham, G.1    Prezzi, D.2    Harford, S.3
  • 103
    • 77955173179 scopus 로고    scopus 로고
    • Biologics in the treatment of systemic lupus erythematosus
    • Lateef A, Petri M,. Biologics in the treatment of systemic lupus erythematosus. Curr Opin Rheumatol 2010; 22: 504.
    • (2010) Curr Opin Rheumatol , vol.22 , pp. 504
    • Lateef, A.1    Petri, M.2
  • 104
    • 84856795563 scopus 로고    scopus 로고
    • Atacicept in combination with MMF and corticosteroids in lupus nephritis: Results of a prematurely terminated trial
    • Ginzler EM, Wax S, Rajeswaran A, et al,. Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial. Arthritis Res Ther 2012; 14: R33.
    • (2012) Arthritis Res Ther , vol.14
    • Ginzler, E.M.1    Wax, S.2    Rajeswaran, A.3
  • 105
    • 59749099913 scopus 로고    scopus 로고
    • B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta
    • Henley T, Kovesdi D, Turner M,. B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta. Eur J Immunol 2008; 38: 3543.
    • (2008) Eur J Immunol , vol.38 , pp. 3543
    • Henley, T.1    Kovesdi, D.2    Turner, M.3
  • 106
    • 0037047590 scopus 로고    scopus 로고
    • Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice
    • Okkenhaug K, Bilancio A, Farjot G, et al,. Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Science 2002; 297: 1031.
    • (2002) Science , vol.297 , pp. 1031
    • Okkenhaug, K.1    Bilancio, A.2    Farjot, G.3
  • 107
    • 30444439101 scopus 로고    scopus 로고
    • Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: Comparative analysis of genetic and pharmacologic interference with p110delta function in B cells
    • Bilancio A, Okkenhaug K, Camps M, et al,. Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells. Blood 2006; 107: 642.
    • (2006) Blood , vol.107 , pp. 642
    • Bilancio, A.1    Okkenhaug, K.2    Camps, M.3
  • 108
    • 67349280350 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation
    • Dil N, Marshall AJ,. Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation. Mol Immunol 2009; 46: 1970.
    • (2009) Mol Immunol , vol.46 , pp. 1970
    • Dil, N.1    Marshall, A.J.2
  • 109
    • 78751553221 scopus 로고    scopus 로고
    • CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
    • Lannutti BJ, Meadows SA, Herman SE, et al,. CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood 2011; 117: 591.
    • (2011) Blood , vol.117 , pp. 591
    • Lannutti, B.J.1    Meadows, S.A.2    Herman, S.E.3
  • 110
    • 84870984149 scopus 로고    scopus 로고
    • The therapeutic potential for PI3K inhibitors in autoimmune rheumatic diseases
    • Banham-Hall E, Clatworthy MR, Okkenhaug K,. The therapeutic potential for PI3K inhibitors in autoimmune rheumatic diseases. Open Rheumatol J 2012; 6: 245.
    • (2012) Open Rheumatol J , vol.6 , pp. 245
    • Banham-Hall, E.1    Clatworthy, M.R.2    Okkenhaug, K.3
  • 111
    • 84873536866 scopus 로고    scopus 로고
    • IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells
    • Ding BB, Bi E, Chen H, Yu JJ, Ye BH,. IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells. J Immunol 2013; 190: 1827.
    • (2013) J Immunol , vol.190 , pp. 1827
    • Ding, B.B.1    Bi, E.2    Chen, H.3    Yu, J.J.4    Ye, B.H.5
  • 112
    • 38449094444 scopus 로고    scopus 로고
    • IL-6 contributes to the expression of RAGs in human mature B cells
    • Hillion S, Dueymes M, Youinou P, Jamin C,. IL-6 contributes to the expression of RAGs in human mature B cells. J Immunol 2007; 179: 6790.
    • (2007) J Immunol , vol.179 , pp. 6790
    • Hillion, S.1    Dueymes, M.2    Youinou, P.3    Jamin, C.4
  • 113
    • 84855981278 scopus 로고    scopus 로고
    • Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates
    • Badell IR, Thompson PW, Turner AP, et al,. Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates. Am J Transplant 2012; 12: 126.
    • (2012) Am J Transplant , vol.12 , pp. 126
    • Badell, I.R.1    Thompson, P.W.2    Turner, A.P.3
  • 114
    • 84864478677 scopus 로고    scopus 로고
    • A novel monoclonal antibody to CD40 prolongs islet allograft survival
    • Lowe M, Badell IR, Thompson P, et al,. A novel monoclonal antibody to CD40 prolongs islet allograft survival. Am J Transplant 2012; 12: 2079.
    • (2012) Am J Transplant , vol.12 , pp. 2079
    • Lowe, M.1    Badell, I.R.2    Thompson, P.3
  • 115
    • 77149122105 scopus 로고    scopus 로고
    • IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
    • Linterman MA, Beaton L, Yu D, et al,. IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J Exp Med 2010; 207: 353.
    • (2010) J Exp Med , vol.207 , pp. 353
    • Linterman, M.A.1    Beaton, L.2    Yu, D.3
  • 116
    • 77149142640 scopus 로고    scopus 로고
    • IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
    • Zotos D, Coquet JM, Zhang Y, et al,. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med 2010; 207: 365.
    • (2010) J Exp Med , vol.207 , pp. 365
    • Zotos, D.1    Coquet, J.M.2    Zhang, Y.3
  • 117
    • 77954500603 scopus 로고    scopus 로고
    • Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner
    • Bessa J, Kopf M, Bachmann MF,. Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner. J Immunol 2010; 184: 4615.
    • (2010) J Immunol , vol.184 , pp. 4615
    • Bessa, J.1    Kopf, M.2    Bachmann, M.F.3
  • 118
    • 84856911519 scopus 로고    scopus 로고
    • Cutting edge: IL-21 derived from human follicular helper T cells acts as a survival factor for secondary lymphoid organ, but not for bone marrow, plasma cells
    • Rodriguez-Bayona B, Ramos-Amaya A, Bernal J, Campos-Caro A, Brieva JA,. Cutting edge: IL-21 derived from human follicular helper T cells acts as a survival factor for secondary lymphoid organ, but not for bone marrow, plasma cells. J Immunol 2012; 188: 1578.
    • (2012) J Immunol , vol.188 , pp. 1578
    • Rodriguez-Bayona, B.1    Ramos-Amaya, A.2    Bernal, J.3    Campos-Caro, A.4    Brieva, J.A.5
  • 119
    • 33947215987 scopus 로고    scopus 로고
    • IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression
    • Herber D, Brown TP, Liang S, Young DA, Collins M, Dunussi-Joannopoulos K,. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J Immunol 2007; 178: 3822.
    • (2007) J Immunol , vol.178 , pp. 3822
    • Herber, D.1    Brown, T.P.2    Liang, S.3    Young, D.A.4    Collins, M.5    Dunussi-Joannopoulos, K.6
  • 120
    • 84862909139 scopus 로고    scopus 로고
    • Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes
    • Hippen KL, Bucher C, Schirm DK, et al,. Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes. Blood 2012; 119: 619.
    • (2012) Blood , vol.119 , pp. 619
    • Hippen, K.L.1    Bucher, C.2    Schirm, D.K.3
  • 121
    • 61449162967 scopus 로고    scopus 로고
    • Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature
    • Mohr E, Serre K, Manz RA, et al,. Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature. J Immunol 2009; 182: 2113.
    • (2009) J Immunol , vol.182 , pp. 2113
    • Mohr, E.1    Serre, K.2    Manz, R.A.3
  • 123
    • 84871158451 scopus 로고    scopus 로고
    • Regulation of Allograft Survival by Inhibitory FcgammaRIIb Signaling
    • Callaghan CJ, Win TS, Motallebzadeh R, et al,. Regulation of Allograft Survival by Inhibitory FcgammaRIIb Signaling. J Immunol 2012; 189: 5694.
    • (2012) J Immunol , vol.189 , pp. 5694
    • Callaghan, C.J.1    Win, T.S.2    Motallebzadeh, R.3
  • 124
    • 33749368008 scopus 로고    scopus 로고
    • CD32B, the human inhibitory Fc-gamma receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma
    • Rankin CT, Veri MC, Gorlatov S, et al,. CD32B, the human inhibitory Fc-gamma receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma. Blood 2006; 108: 2384.
    • (2006) Blood , vol.108 , pp. 2384
    • Rankin, C.T.1    Veri, M.C.2    Gorlatov, S.3
  • 125
    • 43549111441 scopus 로고    scopus 로고
    • CD32B is highly expressed on clonal plasma cells from patients with systemic light-chain amyloidosis and provides a target for monoclonal antibody-based therapy
    • Zhou P, Comenzo RL, Olshen AB, et al,. CD32B is highly expressed on clonal plasma cells from patients with systemic light-chain amyloidosis and provides a target for monoclonal antibody-based therapy. Blood 2008; 111: 3403.
    • (2008) Blood , vol.111 , pp. 3403
    • Zhou, P.1    Comenzo, R.L.2    Olshen, A.B.3
  • 126
    • 53749095799 scopus 로고    scopus 로고
    • Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
    • Dorner T, Kaufmann J, Wegener WA, Teoh N, Goldenberg DM, Burmester GR,. Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus. Arthritis Res Ther 2006; 8: R74.
    • (2006) Arthritis Res Ther , vol.8
    • Dorner, T.1    Kaufmann, J.2    Wegener, W.A.3    Teoh, N.4    Goldenberg, D.M.5    Burmester, G.R.6
  • 127
    • 41849121941 scopus 로고    scopus 로고
    • Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls
    • Jacobi AM, Goldenberg DM, Hiepe F, Radbruch A, Burmester GR, Dorner T,. Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls. Ann Rheum Dis 2008; 67: 450.
    • (2008) Ann Rheum Dis , vol.67 , pp. 450
    • Jacobi, A.M.1    Goldenberg, D.M.2    Hiepe, F.3    Radbruch, A.4    Burmester, G.R.5    Dorner, T.6
  • 128
    • 77956566546 scopus 로고    scopus 로고
    • IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes
    • Seite JF, Cornec D, Renaudineau Y, Youinou P, Mageed RA, Hillion S,. IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes. Blood 2010; 116: 1698.
    • (2010) Blood , vol.116 , pp. 1698
    • Seite, J.F.1    Cornec, D.2    Renaudineau, Y.3    Youinou, P.4    Mageed, R.A.5    Hillion, S.6
  • 129
    • 84871276532 scopus 로고    scopus 로고
    • B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo
    • Schwab I, Seeling M, Biburger M, Aschermann S, Nitschke L, Nimmerjahn F,. B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo. Eur J Immunol 2012; 42: 3302.
    • (2012) Eur J Immunol , vol.42 , pp. 3302
    • Schwab, I.1    Seeling, M.2    Biburger, M.3    Aschermann, S.4    Nitschke, L.5    Nimmerjahn, F.6
  • 130
    • 77949798304 scopus 로고    scopus 로고
    • An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance
    • Zhao G, Moore DJ, Lee KM, et al,. An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance. Am J Transplant 2010; 10: 796.
    • (2010) Am J Transplant , vol.10 , pp. 796
    • Zhao, G.1    Moore, D.J.2    Lee, K.M.3
  • 131
    • 77951640991 scopus 로고    scopus 로고
    • Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells
    • Yang M, Sun L, Wang S, et al,. Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells. J Immunol 2010; 184: 3321.
    • (2010) J Immunol , vol.184 , pp. 3321
    • Yang, M.1    Sun, L.2    Wang, S.3
  • 132
    • 84868619716 scopus 로고    scopus 로고
    • Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
    • Yoshizaki A, Miyagaki T, DiLillo DJ, et al,. Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature 2012; 491: 264.
    • (2012) Nature , vol.491 , pp. 264
    • Yoshizaki, A.1    Miyagaki, T.2    Dilillo, D.J.3
  • 133
    • 77954950402 scopus 로고    scopus 로고
    • Atacicept: Targeting B cells in multiple sclerosis
    • Hartung HP, Kieseier BC,. Atacicept: targeting B cells in multiple sclerosis. Ther Adv Neurol Disord 2010; 3: 205.
    • (2010) Ther Adv Neurol Disord , vol.3 , pp. 205
    • Hartung, H.P.1    Kieseier, B.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.