메뉴 건너뛰기




Volumn 4, Issue DEC, 2013, Pages

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes

Author keywords

Dendritic cell; Inflammation; Lymphatic vessel; Migration; T cell

Indexed keywords


EID: 84892165135     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00433     Document Type: Review
Times cited : (31)

References (161)
  • 1
    • 0242330142 scopus 로고    scopus 로고
    • Lymphatic endothelium: morphological, molecular and functional properties
    • doi:10.1083/jcb.200308082
    • Pepper MS, Skobe M. Lymphatic endothelium: morphological, molecular and functional properties. J Cell Biol (2003) 163:209-13. doi:10.1083/jcb.200308082.
    • (2003) J Cell Biol , vol.163 , pp. 209-213
    • Pepper, M.S.1    Skobe, M.2
  • 2
    • 84861698980 scopus 로고    scopus 로고
    • Lymph node homing of T cells and dendritic cells via afferent lymphatics
    • doi:10.1016/j.it.2012.02.007
    • Forster R, Braun A, Worbs T. Lymph node homing of T cells and dendritic cells via afferent lymphatics. Trends Immunol (2012) 33:271-80. doi:10.1016/j.it.2012.02.007.
    • (2012) Trends Immunol , vol.33 , pp. 271-280
    • Forster, R.1    Braun, A.2    Worbs, T.3
  • 3
    • 0025343120 scopus 로고
    • Naive and memory T cells show distinct pathways of lymphocyte recirculation
    • doi:10.1084/jem.171.3.801
    • Mackay CR, Marston WL, Dudler L. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J Exp Med (1990) 171:801-17. doi:10.1084/jem.171.3.801.
    • (1990) J Exp Med , vol.171 , pp. 801-817
    • Mackay, C.R.1    Marston, W.L.2    Dudler, L.3
  • 4
    • 0032904276 scopus 로고    scopus 로고
    • The physiology of lymphocyte migration through the single lymph node in vivo
    • doi:10.1006/smim.1999.0163
    • Young AJ. The physiology of lymphocyte migration through the single lymph node in vivo. Semin Immunol (1999) 11:73-83. doi:10.1006/smim.1999.0163.
    • (1999) Semin Immunol , vol.11 , pp. 73-83
    • Young, A.J.1
  • 5
    • 77949747054 scopus 로고    scopus 로고
    • Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice
    • doi:10.1172/JCI40926
    • Tomura M, Honda T, Tanizaki H, Otsuka A, Egawa G, Tokura Y, et al. Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest (2010) 120:883-93. doi:10.1172/JCI40926.
    • (2010) J Clin Invest , vol.120 , pp. 883-893
    • Tomura, M.1    Honda, T.2    Tanizaki, H.3    Otsuka, A.4    Egawa, G.5    Tokura, Y.6
  • 6
    • 0018608567 scopus 로고
    • A study of cells present in peripheral lymph of pigs with special reference to a type of cell resembling the Langerhans cell
    • doi:10.1007/BF00220434
    • Drexhage HA, Mullink H, De Groot J, Clarke J, Balfour BM. A study of cells present in peripheral lymph of pigs with special reference to a type of cell resembling the Langerhans cell. Cell Tissue Res (1979) 202:407-30. doi:10.1007/BF00220434.
    • (1979) Cell Tissue Res , vol.202 , pp. 407-430
    • Drexhage, H.A.1    Mullink, H.2    De Groot, J.3    Clarke, J.4    Balfour, B.M.5
  • 7
    • 0018898249 scopus 로고
    • Large mononuclear (veiled) cells like 'Ia-like' membrane antigens in human afferent lympn
    • Spry CJ, Pflug AJ, Janossy G, Humphrey JH. Large mononuclear (veiled) cells like 'Ia-like' membrane antigens in human afferent lympn. Clin Exp Immunol (1980) 39:750-5.
    • (1980) Clin Exp Immunol , vol.39 , pp. 750-755
    • Spry, C.J.1    Pflug, A.J.2    Janossy, G.3    Humphrey, J.H.4
  • 8
    • 0020510488 scopus 로고
    • Characterization of nonlymphoid cells derived from rat peripheral lymph
    • doi:10.1084/jem.157.6.1758
    • Pugh CW, Macpherson GG, Steer HW. Characterization of nonlymphoid cells derived from rat peripheral lymph. J Exp Med (1983) 157:1758-79. doi:10.1084/jem.157.6.1758.
    • (1983) J Exp Med , vol.157 , pp. 1758-1779
    • Pugh, C.W.1    Macpherson, G.G.2    Steer, H.W.3
  • 9
    • 0022652789 scopus 로고
    • Functional characteristics of the veiled cells in afferent lymph from the rat intestine
    • Mayrhofer G, Holt PG, Papadimitriou JM. Functional characteristics of the veiled cells in afferent lymph from the rat intestine. Immunology (1986) 58:379-87.
    • (1986) Immunology , vol.58 , pp. 379-387
    • Mayrhofer, G.1    Holt, P.G.2    Papadimitriou, J.M.3
  • 10
    • 70449732252 scopus 로고    scopus 로고
    • Dendritic cell subsets in primary and secondary T cell responses at body surfaces
    • doi:10.1038/ni.1822
    • Heath WR, Carbone FR. Dendritic cell subsets in primary and secondary T cell responses at body surfaces. Nat Immunol (2009) 10:1237-44. doi:10.1038/ni.1822.
    • (2009) Nat Immunol , vol.10 , pp. 1237-1244
    • Heath, W.R.1    Carbone, F.R.2
  • 11
    • 4143096772 scopus 로고    scopus 로고
    • CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
    • doi:10.1016/j.immuni.2004.06.014
    • Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, Zwirner J, et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity (2004) 21:279-88. doi:10.1016/j.immuni.2004.06.014.
    • (2004) Immunity , vol.21 , pp. 279-288
    • Ohl, L.1    Mohaupt, M.2    Czeloth, N.3    Hintzen, G.4    Kiafard, Z.5    Zwirner, J.6
  • 12
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • doi:10.1084/jem.20020991
    • Scheinecker C, Mchugh R, Shevach EM, Germain RN. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med (2002) 196:1079-90. doi:10.1084/jem.20020991.
    • (2002) J Exp Med , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    Mchugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 13
    • 4444383117 scopus 로고    scopus 로고
    • Langerhans cells activate naive self-antigen-specific CD8 T cells in the steady state
    • doi:10.1016/j.immuni.2004.07.019
    • Mayerova D, Parke EA, Bursch LS, Odumade OA, Hogquist KA. Langerhans cells activate naive self-antigen-specific CD8 T cells in the steady state. Immunity (2004) 21:391-400. doi:10.1016/j.immuni.2004.07.019.
    • (2004) Immunity , vol.21 , pp. 391-400
    • Mayerova, D.1    Parke, E.A.2    Bursch, L.S.3    Odumade, O.A.4    Hogquist, K.A.5
  • 14
    • 37549030450 scopus 로고    scopus 로고
    • Blood-derived dermal Langerin+ dendritic cells survey the skin in the steady state
    • doi:10.1084/jem.20071733
    • Ginhoux F, Collin MP, Bogunovic M, Abel M, Leboeuf M, Helft J, et al. Blood-derived dermal Langerin+ dendritic cells survey the skin in the steady state. J Exp Med (2007) 204:3133-46. doi:10.1084/jem.20071733.
    • (2007) J Exp Med , vol.204 , pp. 3133-3146
    • Ginhoux, F.1    Collin, M.P.2    Bogunovic, M.3    Abel, M.4    Leboeuf, M.5    Helft, J.6
  • 15
    • 84255177550 scopus 로고    scopus 로고
    • Lymph node T cell homeostasis relies on steady state homing of dendritic cells
    • doi:10.1016/j.immuni.2011.10.017
    • Wendland M, Willenzon S, Kocks J, Davalos-Misslitz AC, Hammerschmidt SI, Schumann K, et al. Lymph node T cell homeostasis relies on steady state homing of dendritic cells. Immunity (2011) 35:945-57. doi:10.1016/j.immuni.2011.10.017.
    • (2011) Immunity , vol.35 , pp. 945-957
    • Wendland, M.1    Willenzon, S.2    Kocks, J.3    Davalos-Misslitz, A.C.4    Hammerschmidt, S.I.5    Schumann, K.6
  • 16
    • 0025147473 scopus 로고
    • Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization
    • Kripke ML, Munn CG, Jeevan A, Tang JM, Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J Immunol (1990) 145:2833-8.
    • (1990) J Immunol , vol.145 , pp. 2833-2838
    • Kripke, M.L.1    Munn, C.G.2    Jeevan, A.3    Tang, J.M.4    Bucana, C.5
  • 17
    • 34948814992 scopus 로고    scopus 로고
    • Functionally specialized junctions between endothelial cells of lymphatic vessels
    • doi:10.1084/jem.20062596
    • Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med (2007) 204:2349-62. doi:10.1084/jem.20062596.
    • (2007) J Exp Med , vol.204 , pp. 2349-2362
    • Baluk, P.1    Fuxe, J.2    Hashizume, H.3    Romano, T.4    Lashnits, E.5    Butz, S.6
  • 19
    • 0031783179 scopus 로고    scopus 로고
    • Functional microanatomy of initial lymphatics with special consideration of the extracellular matrix
    • Castenholz A. Functional microanatomy of initial lymphatics with special consideration of the extracellular matrix. Lymphology (1998) 31:101-18.
    • (1998) Lymphology , vol.31 , pp. 101-118
    • Castenholz, A.1
  • 20
    • 73949156419 scopus 로고    scopus 로고
    • Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
    • doi:10.1084/jem.20091739
    • Pflicke H, Sixt M. Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels. J Exp Med (2009) 206:2925-35. doi:10.1084/jem.20091739.
    • (2009) J Exp Med , vol.206 , pp. 2925-2935
    • Pflicke, H.1    Sixt, M.2
  • 21
    • 84861645540 scopus 로고    scopus 로고
    • Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation
    • doi:10.1016/j.ajpath.2012.02.019
    • Yao LC, Baluk P, Srinivasan RS, Oliver G, Mcdonald DM. Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol (2012) 180:2561-75. doi:10.1016/j.ajpath.2012.02.019.
    • (2012) Am J Pathol , vol.180 , pp. 2561-2575
    • Yao, L.C.1    Baluk, P.2    Srinivasan, R.S.3    Oliver, G.4    Mcdonald, D.M.5
  • 22
    • 2642641324 scopus 로고    scopus 로고
    • Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C
    • doi:10.1074/jbc.273.14.8413
    • Ristimaki A, Narko K, Enholm B, Joukov V, Alitalo K. Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J Biol Chem (1998) 273:8413-8. doi:10.1074/jbc.273.14.8413.
    • (1998) J Biol Chem , vol.273 , pp. 8413-8418
    • Ristimaki, A.1    Narko, K.2    Enholm, B.3    Joukov, V.4    Alitalo, K.5
  • 23
    • 63849230366 scopus 로고    scopus 로고
    • Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages
    • doi:10.1182/blood-2008-07-166934
    • Kang S, Lee SP, Kim KE, Kim HZ, Memet S, Koh GY. Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages. Blood (2009) 113:2605-13. doi:10.1182/blood-2008-07-166934.
    • (2009) Blood , vol.113 , pp. 2605-2613
    • Kang, S.1    Lee, S.P.2    Kim, K.E.3    Kim, H.Z.4    Memet, S.5    Koh, G.Y.6
  • 24
    • 0035122695 scopus 로고    scopus 로고
    • Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
    • doi:10.1038/84651
    • Makinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, et al. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med (2001) 7:199-205. doi:10.1038/84651.
    • (2001) Nat Med , vol.7 , pp. 199-205
    • Makinen, T.1    Jussila, L.2    Veikkola, T.3    Karpanen, T.4    Kettunen, M.I.5    Pulkkanen, K.J.6
  • 25
    • 65049085803 scopus 로고    scopus 로고
    • Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis
    • doi:10.1038/jid.2008.351
    • Kajiya K, Sawane M, Huggenberger R, Detmar M. Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis. J Invest Dermatol (2009) 129:1292-8. doi:10.1038/jid.2008.351.
    • (2009) J Invest Dermatol , vol.129 , pp. 1292-1298
    • Kajiya, K.1    Sawane, M.2    Huggenberger, R.3    Detmar, M.4
  • 26
    • 75649083174 scopus 로고    scopus 로고
    • Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1
    • doi:10.1182/blood-2008-12-196840
    • Flister MJ, Wilber A, Hall KL, Iwata C, Miyazono K, Nisato RE, et al. Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1. Blood (2010) 115:418-29. doi:10.1182/blood-2008-12-196840.
    • (2010) Blood , vol.115 , pp. 418-429
    • Flister, M.J.1    Wilber, A.2    Hall, K.L.3    Iwata, C.4    Miyazono, K.5    Nisato, R.E.6
  • 27
    • 77957742772 scopus 로고    scopus 로고
    • Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation
    • doi:10.1084/jem.20100559
    • Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M. Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation. J Exp Med (2010) 207:2255-69. doi:10.1084/jem.20100559.
    • (2010) J Exp Med , vol.207 , pp. 2255-2269
    • Huggenberger, R.1    Ullmann, S.2    Proulx, S.T.3    Pytowski, B.4    Alitalo, K.5    Detmar, M.6
  • 28
    • 33947632923 scopus 로고    scopus 로고
    • Inflammation, lymphatic function, and dendritic cell migration
    • doi:10.1089/lrb.2006.4406
    • Angeli V, Randolph GJ. Inflammation, lymphatic function, and dendritic cell migration. Lymphat Res Biol (2006) 4:217-28. doi:10.1089/lrb.2006.4406.
    • (2006) Lymphat Res Biol , vol.4 , pp. 217-228
    • Angeli, V.1    Randolph, G.J.2
  • 29
    • 33751528001 scopus 로고    scopus 로고
    • An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium
    • doi:10.1084/jem.20051759
    • Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J Exp Med (2006) 203:2763-77. doi:10.1084/jem.20051759.
    • (2006) J Exp Med , vol.203 , pp. 2763-2777
    • Johnson, L.A.1    Clasper, S.2    Holt, A.P.3    Lalor, P.F.4    Baban, D.5    Jackson, D.G.6
  • 30
    • 79960127293 scopus 로고    scopus 로고
    • Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner
    • doi:10.1182/blood-2010-12-326447
    • Vigl B, Aebischer D, Nitschke M, Iolyeva M, Rothlin T, Antsiferova O, et al. Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. Blood (2011) 118:205-15. doi:10.1182/blood-2010-12-326447.
    • (2011) Blood , vol.118 , pp. 205-215
    • Vigl, B.1    Aebischer, D.2    Nitschke, M.3    Iolyeva, M.4    Rothlin, T.5    Antsiferova, O.6
  • 31
    • 77957365260 scopus 로고    scopus 로고
    • Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration
    • doi:10.1093/intimm/dxq435
    • Johnson LA, Jackson DG. Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration. Int Immunol (2010) 22:839-49. doi:10.1093/intimm/dxq435.
    • (2010) Int Immunol , vol.22 , pp. 839-849
    • Johnson, L.A.1    Jackson, D.G.2
  • 32
    • 84855316492 scopus 로고    scopus 로고
    • Lymphatic function is regulated by a coordinated expression of lymphangiogenic and anti-lymphangiogenic cytokines
    • doi:10.1152/ajpcell.00306.2011
    • Zampell JC, Avraham T, Yoder N, Fort N, Yan A, Weitman ES, et al. Lymphatic function is regulated by a coordinated expression of lymphangiogenic and anti-lymphangiogenic cytokines. Am J Physiol Cell Physiol (2012) 302:C392-404. doi:10.1152/ajpcell.00306.2011.
    • (2012) Am J Physiol Cell Physiol , vol.302
    • Zampell, J.C.1    Avraham, T.2    Yoder, N.3    Fort, N.4    Yan, A.5    Weitman, E.S.6
  • 33
    • 77950899035 scopus 로고    scopus 로고
    • Transmural flow modulates cell and fluid transport functions of lymphatic endothelium
    • doi:10.1161/CIRCRESAHA.109.207274
    • Miteva DO, Rutkowski JM, Dixon JB, Kilarski W, Shields JD, Swartz MA. Transmural flow modulates cell and fluid transport functions of lymphatic endothelium. Circ Res (2010) 106:920-31. doi:10.1161/CIRCRESAHA.109.207274.
    • (2010) Circ Res , vol.106 , pp. 920-931
    • Miteva, D.O.1    Rutkowski, J.M.2    Dixon, J.B.3    Kilarski, W.4    Shields, J.D.5    Swartz, M.A.6
  • 34
    • 80555153996 scopus 로고    scopus 로고
    • DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling
    • doi:10.1084/jem.20102392
    • Tal O, Lim HY, Gurevich I, Milo I, Shipony Z, Ng LG, et al. DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling. J Exp Med (2011) 208:2141-53. doi:10.1084/jem.20102392.
    • (2011) J Exp Med , vol.208 , pp. 2141-2153
    • Tal, O.1    Lim, H.Y.2    Gurevich, I.3    Milo, I.4    Shipony, Z.5    Ng, L.G.6
  • 35
    • 33846246384 scopus 로고    scopus 로고
    • Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells
    • doi:10.1016/j.immuni.2007.01.002
    • Alon R, Dustin ML. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity (2007) 26:17-27. doi:10.1016/j.immuni.2007.01.002.
    • (2007) Immunity , vol.26 , pp. 17-27
    • Alon, R.1    Dustin, M.L.2
  • 36
    • 70449713764 scopus 로고    scopus 로고
    • Mast cell-derived particles deliver peripheral signals to remote lymph nodes
    • doi:10.1084/jem.20090805
    • Kunder CA, St John AL, Li G, Leong KW, Berwin B, Staats HF, et al. Mast cell-derived particles deliver peripheral signals to remote lymph nodes. J Exp Med (2009) 206:2455-67. doi:10.1084/jem.20090805.
    • (2009) J Exp Med , vol.206 , pp. 2455-2467
    • Kunder, C.A.1    St John, A.L.2    Li, G.3    Leong, K.W.4    Berwin, B.5    Staats, H.F.6
  • 37
    • 81555208985 scopus 로고    scopus 로고
    • Mast cell modulation of the vascular and lymphatic endothelium
    • doi:10.1182/blood-2011-07-358432
    • Kunder CA, St John AL, Abraham SN. Mast cell modulation of the vascular and lymphatic endothelium. Blood (2011) 118:5383-93. doi:10.1182/blood-2011-07-358432.
    • (2011) Blood , vol.118 , pp. 5383-5393
    • Kunder, C.A.1    St John, A.L.2    Abraham, S.N.3
  • 38
    • 32244443955 scopus 로고    scopus 로고
    • B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization
    • doi:10.1016/j.immuni.2006.01.003
    • Angeli V, Ginhoux F, Llodra J, Quemeneur L, Frenette PS, Skobe M, et al. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 24:203-15. doi:10.1016/j.immuni.2006.01.003.
    • (2006) Immunity , vol.24 , pp. 203-215
    • Angeli, V.1    Ginhoux, F.2    Llodra, J.3    Quemeneur, L.4    Frenette, P.S.5    Skobe, M.6
  • 39
    • 32244437696 scopus 로고    scopus 로고
    • An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration
    • doi:10.1016/j.immuni.2006.01.011
    • Halin C, Detmar M. An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration. Immunity (2006) 24:129-31. doi:10.1016/j.immuni.2006.01.011.
    • (2006) Immunity , vol.24 , pp. 129-131
    • Halin, C.1    Detmar, M.2
  • 40
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics
    • doi:10.1038/ni1240
    • Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol (2005) 6:895-901. doi:10.1038/ni1240.
    • (2005) Nat Immunol , vol.6 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 41
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • doi:10.1038/ni1238
    • Debes GF, Arnold CN, Young AJ, Krautwald S, Lipp M, Hay JB, et al. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat Immunol (2005) 6:889-94. doi:10.1038/ni1238.
    • (2005) Nat Immunol , vol.6 , pp. 889-894
    • Debes, G.F.1    Arnold, C.N.2    Young, A.J.3    Krautwald, S.4    Lipp, M.5    Hay, J.B.6
  • 42
    • 78049518356 scopus 로고    scopus 로고
    • Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation
    • doi:10.4049/jimmunol.1000676
    • Brown MN, Fintushel SR, Lee MH, Jennrich S, Geherin SA, Hay JB, et al. Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation. J Immunol (2010) 185:4873-82. doi:10.4049/jimmunol.1000676.
    • (2010) J Immunol , vol.185 , pp. 4873-4882
    • Brown, M.N.1    Fintushel, S.R.2    Lee, M.H.3    Jennrich, S.4    Geherin, S.A.5    Hay, J.B.6
  • 43
    • 78049413094 scopus 로고    scopus 로고
    • Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants
    • doi:10.4049/jimmunol.1001289
    • Yang CW, Strong BS, Miller MJ, Unanue ER. Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants. J Immunol (2010) 185:2927-34. doi:10.4049/jimmunol.1001289.
    • (2010) J Immunol , vol.185 , pp. 2927-2934
    • Yang, C.W.1    Strong, B.S.2    Miller, M.J.3    Unanue, E.R.4
  • 44
    • 79251559088 scopus 로고    scopus 로고
    • CCR7 is involved in the migration of neutrophils to lymph nodes
    • doi:10.1182/blood-2009-11-254490
    • Beauvillain C, Cunin P, Doni A, Scotet M, Jaillon S, Loiry ML, et al. CCR7 is involved in the migration of neutrophils to lymph nodes. Blood (2011) 117:1196-204. doi:10.1182/blood-2009-11-254490.
    • (2011) Blood , vol.117 , pp. 1196-1204
    • Beauvillain, C.1    Cunin, P.2    Doni, A.3    Scotet, M.4    Jaillon, S.5    Loiry, M.L.6
  • 45
    • 83755194821 scopus 로고    scopus 로고
    • Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
    • doi:10.1371/journal.pone.0029300
    • Alfaro C, Suarez N, Onate C, Perez-Gracia JL, Martinez-Forero I, Hervas-Stubbs S, et al. Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes. PLoS One (2011) 6:e29300. doi:10.1371/journal.pone.0029300.
    • (2011) PLoS One , vol.6
    • Alfaro, C.1    Suarez, N.2    Onate, C.3    Perez-Gracia, J.L.4    Martinez-Forero, I.5    Hervas-Stubbs, S.6
  • 47
    • 77953264387 scopus 로고    scopus 로고
    • Heterogeneity and plasticity of lymphatic endothelial cells
    • doi:10.1055/s-0030-1253457
    • Lee S, Choi I, Hong YK. Heterogeneity and plasticity of lymphatic endothelial cells. Semin Thromb Hemost (2010) 36:352-61. doi:10.1055/s-0030-1253457.
    • (2010) Semin Thromb Hemost , vol.36 , pp. 352-361
    • Lee, S.1    Choi, I.2    Hong, Y.K.3
  • 48
    • 27744558608 scopus 로고    scopus 로고
    • Isolation and characterization of a novel mouse lymphatic endothelial cell line: SV-LEC
    • doi:10.1089/lrb.2005.3.105
    • Ando T, Jordan P, Joh T, Wang Y, Jennings MH, Houghton J, et al. Isolation and characterization of a novel mouse lymphatic endothelial cell line: SV-LEC. Lymphat Res Biol (2005) 3:105-15. doi:10.1089/lrb.2005.3.105.
    • (2005) Lymphat Res Biol , vol.3 , pp. 105-115
    • Ando, T.1    Jordan, P.2    Joh, T.3    Wang, Y.4    Jennings, M.H.5    Houghton, J.6
  • 49
    • 33746401490 scopus 로고    scopus 로고
    • Generation and characterization of a mouse lymphatic endothelial cell line
    • doi:10.1007/s00441-006-0171-y
    • Sironi M, Conti A, Bernasconi S, Fra AM, Pasqualini F, Nebuloni M, et al. Generation and characterization of a mouse lymphatic endothelial cell line. Cell Tissue Res (2006) 325:91-100. doi:10.1007/s00441-006-0171-y.
    • (2006) Cell Tissue Res , vol.325 , pp. 91-100
    • Sironi, M.1    Conti, A.2    Bernasconi, S.3    Fra, A.M.4    Pasqualini, F.5    Nebuloni, M.6
  • 50
    • 59749099189 scopus 로고    scopus 로고
    • Phosphate-buffered saline-based nucleofection of primary endothelial cells
    • doi:10.1016/j.ab.2008.12.021
    • Kang J, Ramu S, Lee S, Aguilar B, Ganesan SK, Yoo J, et al. Phosphate-buffered saline-based nucleofection of primary endothelial cells. Anal Biochem (2009) 386:251-5. doi:10.1016/j.ab.2008.12.021.
    • (2009) Anal Biochem , vol.386 , pp. 251-255
    • Kang, J.1    Ramu, S.2    Lee, S.3    Aguilar, B.4    Ganesan, S.K.5    Yoo, J.6
  • 51
    • 79960988887 scopus 로고    scopus 로고
    • Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor
    • doi:10.1182/blood-2010-11-317800
    • Zheng W, Tammela T, Yamamoto M, Anisimov A, Holopainen T, Kaijalainen S, et al. Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor. Blood (2011) 118:1154-62. doi:10.1182/blood-2010-11-317800.
    • (2011) Blood , vol.118 , pp. 1154-1162
    • Zheng, W.1    Tammela, T.2    Yamamoto, M.3    Anisimov, A.4    Holopainen, T.5    Kaijalainen, S.6
  • 52
    • 63449142453 scopus 로고    scopus 로고
    • The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells
    • doi:10.1084/jem.20081211
    • Maddaluno L, Verbrugge SE, Martinoli C, Matteoli G, Chiavelli A, Zeng Y, et al. The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells. J Exp Med (2009) 206:623-35. doi:10.1084/jem.20081211.
    • (2009) J Exp Med , vol.206 , pp. 623-635
    • Maddaluno, L.1    Verbrugge, S.E.2    Martinoli, C.3    Matteoli, G.4    Chiavelli, A.5    Zeng, Y.6
  • 53
    • 79952109911 scopus 로고    scopus 로고
    • Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-alpha
    • doi:10.1002/eji.201040523
    • Rouzaut A, Garasa S, Teijeira A, Gonzalez I, Martinez-Forero I, Suarez N, et al. Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-alpha. Eur J Immunol (2010) 40:3054-63. doi:10.1002/eji.201040523.
    • (2010) Eur J Immunol , vol.40 , pp. 3054-3063
    • Rouzaut, A.1    Garasa, S.2    Teijeira, A.3    Gonzalez, I.4    Martinez-Forero, I.5    Suarez, N.6
  • 54
    • 37349069359 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
    • doi:10.1038/ni1534
    • Ledgerwood LG, Lal G, Zhang N, Garin A, Esses SJ, Ginhoux F, et al. The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol (2008) 9:42-53. doi:10.1038/ni1534.
    • (2008) Nat Immunol , vol.9 , pp. 42-53
    • Ledgerwood, L.G.1    Lal, G.2    Zhang, N.3    Garin, A.4    Esses, S.J.5    Ginhoux, F.6
  • 55
    • 84866421152 scopus 로고    scopus 로고
    • Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation
    • doi:10.1182/blood-2012-03-417923
    • Nitschke M, Aebischer D, Abadier M, Haener S, Lucic M, Vigl B, et al. Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation. Blood (2012) 120:2249-58. doi:10.1182/blood-2012-03-417923.
    • (2012) Blood , vol.120 , pp. 2249-2258
    • Nitschke, M.1    Aebischer, D.2    Abadier, M.3    Haener, S.4    Lucic, M.5    Vigl, B.6
  • 56
    • 84884415845 scopus 로고    scopus 로고
    • Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels
    • doi:10.1038/jid.2013.152
    • Teijeira A, Garasa S, Pelaez R, Azpilikueta A, Ochoa C, Marre D, et al. Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels. J Invest Dermatol (2013) 133:2276-85. doi:10.1038/jid.2013.152.
    • (2013) J Invest Dermatol , vol.133 , pp. 2276-2285
    • Teijeira, A.1    Garasa, S.2    Pelaez, R.3    Azpilikueta, A.4    Ochoa, C.5    Marre, D.6
  • 57
    • 76649119448 scopus 로고    scopus 로고
    • Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study
    • doi:10.1242/jcs.053793
    • Khuon S, Liang L, Dettman RW, Sporn PH, Wysolmerski RB, Chew TL. Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study. J Cell Sci (2010) 123:431-40. doi:10.1242/jcs.053793.
    • (2010) J Cell Sci , vol.123 , pp. 431-440
    • Khuon, S.1    Liang, L.2    Dettman, R.W.3    Sporn, P.H.4    Wysolmerski, R.B.5    Chew, T.L.6
  • 58
    • 84862157431 scopus 로고    scopus 로고
    • Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
    • doi:10.1038/nprot.2012.051
    • Shin Y, Han S, Jeon JS, Yamamoto K, Zervantonakis IK, Sudo R, et al. Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels. Nat Protoc (2012) 7:1247-59. doi:10.1038/nprot.2012.051.
    • (2012) Nat Protoc , vol.7 , pp. 1247-1259
    • Shin, Y.1    Han, S.2    Jeon, J.S.3    Yamamoto, K.4    Zervantonakis, I.K.5    Sudo, R.6
  • 60
    • 0025130986 scopus 로고
    • Migration and maturation of Langerhans cells in skin transplants and explants
    • doi:10.1084/jem.172.5.1483
    • Larsen CP, Steinman RM, Witmer-Pack M, Hankins DF, Morris PJ, Austyn JM. Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med (1990) 172:1483-93. doi:10.1084/jem.172.5.1483.
    • (1990) J Exp Med , vol.172 , pp. 1483-1493
    • Larsen, C.P.1    Steinman, R.M.2    Witmer-Pack, M.3    Hankins, D.F.4    Morris, P.J.5    Austyn, J.M.6
  • 61
    • 43049085527 scopus 로고    scopus 로고
    • Rapid leukocyte migration by integrin-independent flowing and squeezing
    • doi:10.1038/nature06887
    • Lammermann T, Bader BL, Monkley SJ, Worbs T, Wedlich-Soldner R, Hirsch K, et al. Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature (2008) 453:51-5. doi:10.1038/nature06887.
    • (2008) Nature , vol.453 , pp. 51-55
    • Lammermann, T.1    Bader, B.L.2    Monkley, S.J.3    Worbs, T.4    Wedlich-Soldner, R.5    Hirsch, K.6
  • 62
    • 84858209637 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) and CD99 are critical in lymphatic transmigration of human dendritic cells
    • doi:10.1038/jid.2011.420
    • Torzicky M, Viznerova P, Richter S, Strobl H, Scheinecker C, Foedinger D, et al. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) and CD99 are critical in lymphatic transmigration of human dendritic cells. J Invest Dermatol (2012) 132:1149-57. doi:10.1038/jid.2011.420.
    • (2012) J Invest Dermatol , vol.132 , pp. 1149-1157
    • Torzicky, M.1    Viznerova, P.2    Richter, S.3    Strobl, H.4    Scheinecker, C.5    Foedinger, D.6
  • 63
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • doi:10.1038/nri1670
    • Randolph GJ, Angeli V, Swartz MA. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat Rev Immunol (2005) 5:617-28. doi:10.1038/nri1670.
    • (2005) Nat Rev Immunol , vol.5 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 64
    • 0018854287 scopus 로고
    • Distribution of immunogenic cells after painting with the contact sensitizers fluorescein isothiocyanate and oxazolone. Different sensitizers form immunogenic complexes with different cell populations
    • Thomas WR, Edwards AJ, Watkins MC, Asherson GL. Distribution of immunogenic cells after painting with the contact sensitizers fluorescein isothiocyanate and oxazolone. Different sensitizers form immunogenic complexes with different cell populations. Immunology (1980) 39:21-7.
    • (1980) Immunology , vol.39 , pp. 21-27
    • Thomas, W.R.1    Edwards, A.J.2    Watkins, M.C.3    Asherson, G.L.4
  • 65
    • 0033403066 scopus 로고    scopus 로고
    • Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    • doi:10.1016/S1074-7613(00)80149-1
    • Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity (1999) 11:753-61. doi:10.1016/S1074-7613(00)80149-1.
    • (1999) Immunity , vol.11 , pp. 753-761
    • Randolph, G.J.1    Inaba, K.2    Robbiani, D.F.3    Steinman, R.M.4    Muller, W.A.5
  • 66
    • 0026443631 scopus 로고
    • Stimulation of Langerhans cell migration by tumor necrosis factor alpha (TNF-alpha)
    • doi:10.1111/1523-1747.ep12668986
    • Kimber I, Cumberbatch M. Stimulation of Langerhans cell migration by tumor necrosis factor alpha (TNF-alpha). J Invest Dermatol (1992) 99:48S-50S. doi:10.1111/1523-1747.ep12668986.
    • (1992) J Invest Dermatol , vol.99
    • Kimber, I.1    Cumberbatch, M.2
  • 67
    • 0042922810 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
    • doi:10.1084/jem.20030448
    • Martin-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, Lanzavecchia A, et al. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med (2003) 198:615-21. doi:10.1084/jem.20030448.
    • (2003) J Exp Med , vol.198 , pp. 615-621
    • Martin-Fontecha, A.1    Sebastiani, S.2    Hopken, U.E.3    Uguccioni, M.4    Lipp, M.5    Lanzavecchia, A.6
  • 68
    • 78650983951 scopus 로고    scopus 로고
    • Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse
    • doi:10.1182/blood-2010-07-298562
    • Choi I, Chung HK, Ramu S, Lee HN, Kim KE, Lee S, et al. Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse. Blood (2011) 117:362-5. doi:10.1182/blood-2010-07-298562.
    • (2011) Blood , vol.117 , pp. 362-365
    • Choi, I.1    Chung, H.K.2    Ramu, S.3    Lee, H.N.4    Kim, K.E.5    Lee, S.6
  • 69
    • 81855212493 scopus 로고    scopus 로고
    • Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse
    • doi:10.1042/BST20110722
    • Hagerling R, Pollmann C, Kremer L, Andresen V, Kiefer F. Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse. Biochem Soc Trans (2011) 39:1674-81. doi:10.1042/BST20110722.
    • (2011) Biochem Soc Trans , vol.39 , pp. 1674-1681
    • Hagerling, R.1    Pollmann, C.2    Kremer, L.3    Andresen, V.4    Kiefer, F.5
  • 70
    • 84860008988 scopus 로고    scopus 로고
    • In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis
    • doi:10.1073/pnas.1115542109
    • Martinez-Corral I, Olmeda D, Dieguez-Hurtado R, Tammela T, Alitalo K, Ortega S. In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis. Proc Natl Acad Sci U S A (2012) 109:6223-8. doi:10.1073/pnas.1115542109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 6223-6228
    • Martinez-Corral, I.1    Olmeda, D.2    Dieguez-Hurtado, R.3    Tammela, T.4    Alitalo, K.5    Ortega, S.6
  • 71
    • 84871460369 scopus 로고    scopus 로고
    • Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary
    • doi:10.1371/journal.pone.0052620
    • Svingen T, Francois M, Wilhelm D, Koopman P. Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary. PLoS One (2012) 7:e52620. doi:10.1371/journal.pone.0052620.
    • (2012) PLoS One , vol.7
    • Svingen, T.1    Francois, M.2    Wilhelm, D.3    Koopman, P.4
  • 72
    • 84859012418 scopus 로고    scopus 로고
    • ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets
    • doi:10.1016/j.ajpath.2011.12.026
    • Truman LA, Bentley KL, Smith EC, Massaro SA, Gonzalez DG, Haberman AM, et al. ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets. Am J Pathol (2012) 180:1715-25. doi:10.1016/j.ajpath.2011.12.026.
    • (2012) Am J Pathol , vol.180 , pp. 1715-1725
    • Truman, L.A.1    Bentley, K.L.2    Smith, E.C.3    Massaro, S.A.4    Gonzalez, D.G.5    Haberman, A.M.6
  • 73
    • 84874545041 scopus 로고    scopus 로고
    • Intravital immunofluorescence for visualizing the microcirculatory and immune microenvironments in the mouse ear dermis
    • doi:10.1371/journal.pone.0057135
    • Kilarski WW, Guc E, Teo JC, Oliver SR, Lund AW, Swartz MA. Intravital immunofluorescence for visualizing the microcirculatory and immune microenvironments in the mouse ear dermis. PLoS One (2013) 8:e57135. doi:10.1371/journal.pone.0057135.
    • (2013) PLoS One , vol.8
    • Kilarski, W.W.1    Guc, E.2    Teo, J.C.3    Oliver, S.R.4    Lund, A.W.5    Swartz, M.A.6
  • 74
    • 0031712324 scopus 로고    scopus 로고
    • Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
    • doi:10.1002/(SICI)1521-4141(199809)28:09<2760::AID-IMMU2760>3.0.CO;2-N
    • Sallusto F, Schaerli P, Loetscher P, Schaniel C, Lenig D, Mackay CR, et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol (1998) 28:2760-9. doi:10.1002/(SICI)1521-4141(199809)28:09<2760::AID-IMMU2760>3.0.CO;2-N.
    • (1998) Eur J Immunol , vol.28 , pp. 2760-2769
    • Sallusto, F.1    Schaerli, P.2    Loetscher, P.3    Schaniel, C.4    Lenig, D.5    Mackay, C.R.6
  • 75
    • 0035903330 scopus 로고    scopus 로고
    • Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages
    • doi:10.1084/jem.194.6.797
    • Kriehuber E, Breiteneder-Geleff S, Groeger M, Soleiman A, Schoppmann SF, Stingl G, et al. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med (2001) 194:797-808. doi:10.1084/jem.194.6.797.
    • (2001) J Exp Med , vol.194 , pp. 797-808
    • Kriehuber, E.1    Breiteneder-Geleff, S.2    Groeger, M.3    Soleiman, A.4    Schoppmann, S.F.5    Stingl, G.6
  • 76
    • 78649364068 scopus 로고    scopus 로고
    • Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes
    • doi:10.1016/j.immuni.2010.10.018
    • Bao X, Moseman EA, Saito H, Petryniak B, Thiriot A, Hatakeyama S, et al. Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes. Immunity (2010) 33:817-29. doi:10.1016/j.immuni.2010.10.018.
    • (2010) Immunity , vol.33 , pp. 817-829
    • Bao, X.1    Moseman, E.A.2    Saito, H.3    Petryniak, B.4    Thiriot, A.5    Hatakeyama, S.6
  • 77
    • 77953268755 scopus 로고    scopus 로고
    • Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells
    • doi:10.1016/j.immuni.2010.04.017
    • Schumann K, Lammermann T, Bruckner M, Legler DF, Polleux J, Spatz JP, et al. Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells. Immunity (2010) 32:703-13. doi:10.1016/j.immuni.2010.04.017.
    • (2010) Immunity , vol.32 , pp. 703-713
    • Schumann, K.1    Lammermann, T.2    Bruckner, M.3    Legler, D.F.4    Polleux, J.5    Spatz, J.P.6
  • 78
    • 84872435502 scopus 로고    scopus 로고
    • Interstitial dendritic cell guidance by haptotactic chemokine gradients
    • doi:10.1126/science.1228456
    • Weber M, Hauschild R, Schwarz J, Moussion C, De Vries I, Legler DF, et al. Interstitial dendritic cell guidance by haptotactic chemokine gradients. Science (2013) 339:328-32. doi:10.1126/science.1228456.
    • (2013) Science , vol.339 , pp. 328-332
    • Weber, M.1    Hauschild, R.2    Schwarz, J.3    Moussion, C.4    De Vries, I.5    Legler, D.F.6
  • 79
    • 60549110303 scopus 로고    scopus 로고
    • Dendritic cell migration to peripheral lymph nodes
    • doi:10.1007/978-3-540-71029-5_2
    • Martin-Fontecha A, Lanzavecchia A, Sallusto F. Dendritic cell migration to peripheral lymph nodes. Handb Exp Pharmacol (2009) 188:31-49. doi:10.1007/978-3-540-71029-5_2.
    • (2009) Handb Exp Pharmacol , vol.188 , pp. 31-49
    • Martin-Fontecha, A.1    Lanzavecchia, A.2    Sallusto, F.3
  • 80
    • 79952816209 scopus 로고    scopus 로고
    • The lymphoid chemokine CCL21 triggers LFA-1 adhesive properties on human dendritic cells
    • doi:10.1038/icb.2010.103
    • Eich C, De Vries IJ, Linssen PC, De Boer A, Boezeman JB, Figdor CG, et al. The lymphoid chemokine CCL21 triggers LFA-1 adhesive properties on human dendritic cells. Immunol Cell Biol (2011) 89:458-65. doi:10.1038/icb.2010.103.
    • (2011) Immunol Cell Biol , vol.89 , pp. 458-465
    • Eich, C.1    De Vries, I.J.2    Linssen, P.C.3    De Boer, A.4    Boezeman, J.B.5    Figdor, C.G.6
  • 81
    • 84864772197 scopus 로고    scopus 로고
    • CD137 on inflamed lymphatic endothelial cells enhances CCL21-guided migration of dendritic cells
    • doi:10.1096/fj.11-201061
    • Teijeira A, Palazon A, Garasa S, Marre D, Auba C, Rogel A, et al. CD137 on inflamed lymphatic endothelial cells enhances CCL21-guided migration of dendritic cells. FASEB J (2012) 26:3380-92. doi:10.1096/fj.11-201061.
    • (2012) FASEB J , vol.26 , pp. 3380-3392
    • Teijeira, A.1    Palazon, A.2    Garasa, S.3    Marre, D.4    Auba, C.5    Rogel, A.6
  • 82
    • 34249774277 scopus 로고    scopus 로고
    • Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling
    • doi:10.1016/j.ccr.2007.04.020
    • Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell (2007) 11:526-38. doi:10.1016/j.ccr.2007.04.020.
    • (2007) Cancer Cell , vol.11 , pp. 526-538
    • Shields, J.D.1    Fleury, M.E.2    Yong, C.3    Tomei, A.A.4    Randolph, G.J.5    Swartz, M.A.6
  • 83
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • doi:10.1038/44385
    • Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature (1999) 401:708-12. doi:10.1038/44385.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 84
    • 84876910443 scopus 로고    scopus 로고
    • The integration of T cell migration, differentiation and function
    • doi:10.1038/nri3442
    • Masopust D, Schenkel JM. The integration of T cell migration, differentiation and function. Nat Rev Immunol (2013) 13:309-20. doi:10.1038/nri3442.
    • (2013) Nat Rev Immunol , vol.13 , pp. 309-320
    • Masopust, D.1    Schenkel, J.M.2
  • 85
    • 35348901875 scopus 로고    scopus 로고
    • CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells
    • doi:10.2353/ajpath.2007.070225
    • Kabashima K, Shiraishi N, Sugita K, Mori T, Onoue A, Kobayashi M, et al. CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells. Am J Pathol (2007) 171:1249-57. doi:10.2353/ajpath.2007.070225.
    • (2007) Am J Pathol , vol.171 , pp. 1249-1257
    • Kabashima, K.1    Shiraishi, N.2    Sugita, K.3    Mori, T.4    Onoue, A.5    Kobayashi, M.6
  • 87
    • 79957610938 scopus 로고    scopus 로고
    • The outs and the ins of sphingosine-1-phosphate in immunity
    • doi:10.1038/nri2974
    • Spiegel S, Milstien S. The outs and the ins of sphingosine-1-phosphate in immunity. Nat Rev Immunol (2011) 11:403-15. doi:10.1038/nri2974.
    • (2011) Nat Rev Immunol , vol.11 , pp. 403-415
    • Spiegel, S.1    Milstien, S.2
  • 88
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • doi:10.1038/nature02284
    • Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature (2004) 427:355-60. doi:10.1038/nature02284.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1    Lo, C.G.2    Cinamon, G.3    Lesneski, M.J.4    Xu, Y.5    Brinkmann, V.6
  • 89
    • 34247379074 scopus 로고    scopus 로고
    • Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
    • doi:10.1126/science.1139221
    • Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, Xu Y, et al. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science (2007) 316:295-8. doi:10.1126/science.1139221.
    • (2007) Science , vol.316 , pp. 295-298
    • Pappu, R.1    Schwab, S.R.2    Cornelissen, I.3    Pereira, J.P.4    Regard, J.B.5    Xu, Y.6
  • 90
    • 76149126108 scopus 로고    scopus 로고
    • Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
    • doi:10.1084/jem.20091619
    • Pham TH, Baluk P, Xu Y, Grigorova I, Bankovich AJ, Pappu R, et al. Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. J Exp Med (2010) 207:17-27. doi:10.1084/jem.20091619.
    • (2010) J Exp Med , vol.207 , pp. 17-27
    • Pham, T.H.1    Baluk, P.2    Xu, Y.3    Grigorova, I.4    Bankovich, A.J.5    Pappu, R.6
  • 91
    • 23844552403 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate mediates migration of mature dendritic cells
    • Czeloth N, Bernhardt G, Hofmann F, Genth H, Forster R. Sphingosine-1-phosphate mediates migration of mature dendritic cells. J Immunol (2005) 175:2960-7.
    • (2005) J Immunol , vol.175 , pp. 2960-2967
    • Czeloth, N.1    Bernhardt, G.2    Hofmann, F.3    Genth, H.4    Forster, R.5
  • 92
    • 45749113764 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor type-1 agonism impairs blood dendritic cell chemotaxis and skin dendritic cell migration to lymph nodes under inflammatory conditions
    • doi:10.1093/intimm/dxn050
    • Gollmann G, Neuwirt H, Tripp CH, Mueller H, Konwalinka G, Heufler C, et al. Sphingosine-1-phosphate receptor type-1 agonism impairs blood dendritic cell chemotaxis and skin dendritic cell migration to lymph nodes under inflammatory conditions. Int Immunol (2008) 20:911-23. doi:10.1093/intimm/dxn050.
    • (2008) Int Immunol , vol.20 , pp. 911-923
    • Gollmann, G.1    Neuwirt, H.2    Tripp, C.H.3    Mueller, H.4    Konwalinka, G.5    Heufler, C.6
  • 93
    • 77958137496 scopus 로고    scopus 로고
    • The origin and maturity of dendritic cells determine the pattern of sphingosine 1-phosphate receptors expressed and required for efficient migration
    • doi:10.4049/jimmunol.1000568
    • Rathinasamy A, Czeloth N, Pabst O, Forster R, Bernhardt G. The origin and maturity of dendritic cells determine the pattern of sphingosine 1-phosphate receptors expressed and required for efficient migration. J Immunol (2010) 185:4072-81. doi:10.4049/jimmunol.1000568.
    • (2010) J Immunol , vol.185 , pp. 4072-4081
    • Rathinasamy, A.1    Czeloth, N.2    Pabst, O.3    Forster, R.4    Bernhardt, G.5
  • 94
    • 2442679391 scopus 로고    scopus 로고
    • The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors
    • doi:10.1096/fj.03-0910fje
    • Graler MH, Goetzl EJ. The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. FASEB J (2004) 18:551-3. doi:10.1096/fj.03-0910fje.
    • (2004) FASEB J , vol.18 , pp. 551-553
    • Graler, M.H.1    Goetzl, E.J.2
  • 95
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • doi:10.1038/nature04606
    • Shiow LR, Rosen DB, Brdickova N, Xu Y, An J, Lanier LL, et al. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature (2006) 440:540-4. doi:10.1038/nature04606.
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1    Rosen, D.B.2    Brdickova, N.3    Xu, Y.4    An, J.5    Lanier, L.L.6
  • 96
    • 77954591796 scopus 로고    scopus 로고
    • CD69 suppresses sphingosine 1-phosphate receptor-1 (S1P1) function through interaction with membrane helix 4
    • doi:10.1074/jbc.M110.123299
    • Bankovich AJ, Shiow LR, Cyster JG. CD69 suppresses sphingosine 1-phosphate receptor-1 (S1P1) function through interaction with membrane helix 4. J Biol Chem (2010) 285:22328-37. doi:10.1074/jbc.M110.123299.
    • (2010) J Biol Chem , vol.285 , pp. 22328-22337
    • Bankovich, A.J.1    Shiow, L.R.2    Cyster, J.G.3
  • 98
    • 80051603081 scopus 로고    scopus 로고
    • Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium
    • doi:10.4049/jimmunol.1100299
    • Ahmed SR, Mcgettrick HM, Yates CM, Buckley CD, Ratcliffe MJ, Nash GB, et al. Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium. J Immunol (2011) 187:1432-9. doi:10.4049/jimmunol.1100299.
    • (2011) J Immunol , vol.187 , pp. 1432-1439
    • Ahmed, S.R.1    Mcgettrick, H.M.2    Yates, C.M.3    Buckley, C.D.4    Ratcliffe, M.J.5    Nash, G.B.6
  • 99
    • 84888104893 scopus 로고    scopus 로고
    • The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics
    • doi:10.1242/jcs.135343
    • Johnson LA, Jackson DG. The chemokine CX3CL1 promotes trafficking of dendritic cells through inflamed lymphatics. J Cell Sci (2013) 126:5259-70. doi:10.1242/jcs.135343.
    • (2013) J Cell Sci , vol.126 , pp. 5259-5270
    • Johnson, L.A.1    Jackson, D.G.2
  • 100
    • 0345505649 scopus 로고    scopus 로고
    • Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6
    • Fra AM, Locati M, Otero K, Sironi M, Signorelli P, Massardi ML, et al. Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6. J Immunol (2003) 170:2279-82.
    • (2003) J Immunol , vol.170 , pp. 2279-2282
    • Fra, A.M.1    Locati, M.2    Otero, K.3    Sironi, M.4    Signorelli, P.5    Massardi, M.L.6
  • 101
    • 2342637779 scopus 로고    scopus 로고
    • The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines
    • doi:10.1091/mbc.E03-09-0634
    • Weber M, Blair E, Simpson CV, O'Hara M, Blackburn PE, Rot A, et al. The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Mol Biol Cell (2004) 15:2492-508. doi:10.1091/mbc.E03-09-0634.
    • (2004) Mol Biol Cell , vol.15 , pp. 2492-2508
    • Weber, M.1    Blair, E.2    Simpson, C.V.3    O'Hara, M.4    Blackburn, P.E.5    Rot, A.6
  • 102
    • 11144354216 scopus 로고    scopus 로고
    • Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor
    • Bonecchi R, Locati M, Galliera E, Vulcano M, Sironi M, Fra AM, et al. Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor. J Immunol (2004) 172:4972-6.
    • (2004) J Immunol , vol.172 , pp. 4972-4976
    • Bonecchi, R.1    Locati, M.2    Galliera, E.3    Vulcano, M.4    Sironi, M.5    Fra, A.M.6
  • 103
    • 70350015333 scopus 로고    scopus 로고
    • Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence
    • doi:10.1074/jbc.M109.029249
    • Savino B, Borroni EM, Torres NM, Proost P, Struyf S, Mortier A, et al. Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence. J Biol Chem (2009) 284:26207-15. doi:10.1074/jbc.M109.029249.
    • (2009) J Biol Chem , vol.284 , pp. 26207-26215
    • Savino, B.1    Borroni, E.M.2    Torres, N.M.3    Proost, P.4    Struyf, S.5    Mortier, A.6
  • 104
    • 84879709783 scopus 로고    scopus 로고
    • An analysis of the function and expression of D6 on lymphatic endothelial cells
    • doi:10.1182/blood-2012-04-425314
    • McKimmie CS, Singh MD, Hewit K, Lopez-Franco O, Le Brocq M, Rose-John S, et al. An analysis of the function and expression of D6 on lymphatic endothelial cells. Blood (2013) 121:3768-77. doi:10.1182/blood-2012-04-425314.
    • (2013) Blood , vol.121 , pp. 3768-3777
    • McKimmie, C.S.1    Singh, M.D.2    Hewit, K.3    Lopez-Franco, O.4    Le Brocq, M.5    Rose-John, S.6
  • 105
    • 83055179249 scopus 로고    scopus 로고
    • D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion
    • doi:10.1182/blood-2011-03-344044
    • Lee KM, Mckimmie CS, Gilchrist DS, Pallas KJ, Nibbs RJ, Garside P, et al. D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood (2011) 118:6220-9. doi:10.1182/blood-2011-03-344044.
    • (2011) Blood , vol.118 , pp. 6220-6229
    • Lee, K.M.1    Mckimmie, C.S.2    Gilchrist, D.S.3    Pallas, K.J.4    Nibbs, R.J.5    Garside, P.6
  • 106
    • 70350454867 scopus 로고    scopus 로고
    • Non-muscle myosin II takes centre stage in cell adhesion and migration
    • doi:10.1038/nrm2786
    • Vicente-Manzanares M, Ma X, Adelstein RS, Horwitz AR. Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 10:778-90. doi:10.1038/nrm2786.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 778-790
    • Vicente-Manzanares, M.1    Ma, X.2    Adelstein, R.S.3    Horwitz, A.R.4
  • 107
    • 0027984587 scopus 로고
    • In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes
    • doi:10.1006/cimm.1994.1285
    • Ma J, Wang JH, Guo YJ, Sy MS, Bigby M. In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes. Cell Immunol (1994) 158:389-99. doi:10.1006/cimm.1994.1285.
    • (1994) Cell Immunol , vol.158 , pp. 389-399
    • Ma, J.1    Wang, J.H.2    Guo, Y.J.3    Sy, M.S.4    Bigby, M.5
  • 108
    • 0034776392 scopus 로고    scopus 로고
    • The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node
    • doi:10.1002/1521-4141(2001010)31:10<3085::AID-IMMU3085>3.0.CO;2-B
    • Xu H, Guan H, Zu G, Bullard D, Hanson J, Slater M, et al. The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol (2001) 31:3085-93. doi:10.1002/1521-4141(2001010)31:10<3085::AID-IMMU3085>3.0.CO;2-B.
    • (2001) Eur J Immunol , vol.31 , pp. 3085-3093
    • Xu, H.1    Guan, H.2    Zu, G.3    Bullard, D.4    Hanson, J.5    Slater, M.6
  • 110
    • 0037166942 scopus 로고    scopus 로고
    • Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes
    • doi:10.1083/jcb.200112126
    • Barreiro O, Yanez-Mo M, Serrador JM, Montoya MC, Vicente-Manzanares M, Tejedor R, et al. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol (2002) 157:1233-45. doi:10.1083/jcb.200112126.
    • (2002) J Cell Biol , vol.157 , pp. 1233-1245
    • Barreiro, O.1    Yanez-Mo, M.2    Serrador, J.M.3    Montoya, M.C.4    Vicente-Manzanares, M.5    Tejedor, R.6
  • 111
    • 0344585404 scopus 로고    scopus 로고
    • Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1
    • Carman CV, Jun CD, Salas A, Springer TA. Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. J Immunol (2003) 171:6135-44.
    • (2003) J Immunol , vol.171 , pp. 6135-6144
    • Carman, C.V.1    Jun, C.D.2    Salas, A.3    Springer, T.A.4
  • 112
    • 77951597881 scopus 로고    scopus 로고
    • Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
    • doi:10.1038/nrm2889
    • Nourshargh S, Hordijk PL, Sixt M. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol (2010) 11:366-78. doi:10.1038/nrm2889.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 366-378
    • Nourshargh, S.1    Hordijk, P.L.2    Sixt, M.3
  • 113
    • 0037331713 scopus 로고    scopus 로고
    • Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
    • doi:10.1016/S0002-9440(10)63851-5
    • Hirakawa S, Hong YK, Harvey N, Schacht V, Matsuda K, Libermann T, et al. Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol (2003) 162:575-86. doi:10.1016/S0002-9440(10)63851-5.
    • (2003) Am J Pathol , vol.162 , pp. 575-586
    • Hirakawa, S.1    Hong, Y.K.2    Harvey, N.3    Schacht, V.4    Matsuda, K.5    Libermann, T.6
  • 114
    • 33845882730 scopus 로고    scopus 로고
    • Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration
    • doi:10.1038/nn0207-263b
    • Maness PF, Schachner M. Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration. Nat Neurosci (2007) 10:19-26. doi:10.1038/nn0207-263b.
    • (2007) Nat Neurosci , vol.10 , pp. 19-26
    • Maness, P.F.1    Schachner, M.2
  • 115
    • 0031131885 scopus 로고    scopus 로고
    • Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin
    • Pancook JD, Reisfeld RA, Varki N, Vitiello A, Fox RI, Montgomery AM. Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin. J Immunol (1997) 158:4413-21.
    • (1997) J Immunol , vol.158 , pp. 4413-4421
    • Pancook, J.D.1    Reisfeld, R.A.2    Varki, N.3    Vitiello, A.4    Fox, R.I.5    Montgomery, A.M.6
  • 116
    • 84864079969 scopus 로고    scopus 로고
    • Homophilic interaction of the L1 family of cell adhesion molecules
    • doi:10.3858/emm.2012.44.7.050
    • Wei CH, Ryu SE. Homophilic interaction of the L1 family of cell adhesion molecules. Exp Mol Med (2012) 44:413-23. doi:10.3858/emm.2012.44.7.050.
    • (2012) Exp Mol Med , vol.44 , pp. 413-423
    • Wei, C.H.1    Ryu, S.E.2
  • 117
    • 15644366702 scopus 로고    scopus 로고
    • A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins
    • doi:10.1083/jcb.139.6.1567
    • Felding-Habermann B, Silletti S, Mei F, Siu CH, Yip PM, Brooks PC, et al. A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins. J Cell Biol (1997) 139:1567-81. doi:10.1083/jcb.139.6.1567.
    • (1997) J Cell Biol , vol.139 , pp. 1567-1581
    • Felding-Habermann, B.1    Silletti, S.2    Mei, F.3    Siu, C.H.4    Yip, P.M.5    Brooks, P.C.6
  • 119
    • 84874611164 scopus 로고    scopus 로고
    • Novel role for ALCAM in lymphatic network formation and function
    • doi:10.1096/fj.12-217844
    • Iolyeva M, Karaman S, Willrodt AH, Weingartner S, Vigl B, Halin C. Novel role for ALCAM in lymphatic network formation and function. FASEB J (2013) 27:978-90. doi:10.1096/fj.12-217844.
    • (2013) FASEB J , vol.27 , pp. 978-990
    • Iolyeva, M.1    Karaman, S.2    Willrodt, A.H.3    Weingartner, S.4    Vigl, B.5    Halin, C.6
  • 120
    • 10744229023 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates
    • doi:10.1097/01.ASN.0000113316.52371.2E
    • Kerjaschki D, Regele HM, Moosberger I, Nagy-Bojarski K, Watschinger B, Soleiman A, et al. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J Am Soc Nephrol (2004) 15:603-12. doi:10.1097/01.ASN.0000113316.52371.2E.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 603-612
    • Kerjaschki, D.1    Regele, H.M.2    Moosberger, I.3    Nagy-Bojarski, K.4    Watschinger, B.5    Soleiman, A.6
  • 121
    • 0033748035 scopus 로고    scopus 로고
    • Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse
    • doi:10.1073/pnas.97.23.12694
    • Luther SA, Tang HL, Hyman PL, Farr AG, Cyster JG. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc Natl Acad Sci U S A (2000) 97:12694-9. doi:10.1073/pnas.97.23.12694.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12694-12699
    • Luther, S.A.1    Tang, H.L.2    Hyman, P.L.3    Farr, A.G.4    Cyster, J.G.5
  • 122
    • 33845455093 scopus 로고    scopus 로고
    • Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
    • doi:10.1016/j.immuni.2006.10.011
    • Bajenoff M, Egen JG, Koo LY, Laugier JP, Brau F, Glaichenhaus N, et al. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity (2006) 25:989-1001. doi:10.1016/j.immuni.2006.10.011.
    • (2006) Immunity , vol.25 , pp. 989-1001
    • Bajenoff, M.1    Egen, J.G.2    Koo, L.Y.3    Laugier, J.P.4    Brau, F.5    Glaichenhaus, N.6
  • 123
    • 84865401654 scopus 로고    scopus 로고
    • Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2
    • doi:10.1016/j.immuni.2012.05.022
    • Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, et al. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity (2012) 37:276-89. doi:10.1016/j.immuni.2012.05.022.
    • (2012) Immunity , vol.37 , pp. 276-289
    • Acton, S.E.1    Astarita, J.L.2    Malhotra, D.3    Lukacs-Kornek, V.4    Franz, B.5    Hess, P.R.6
  • 124
    • 84855486320 scopus 로고    scopus 로고
    • Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer
    • doi:10.1038/cr.2011.198
    • Sakurai A, Doci CL, Gutkind JS. Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer. Cell Res (2012) 22:23-32. doi:10.1038/cr.2011.198.
    • (2012) Cell Res , vol.22 , pp. 23-32
    • Sakurai, A.1    Doci, C.L.2    Gutkind, J.S.3
  • 125
    • 77953808714 scopus 로고    scopus 로고
    • Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II
    • doi:10.1038/ni.1885
    • Takamatsu H, Takegahara N, Nakagawa Y, Tomura M, Taniguchi M, Friedel RH, et al. Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol (2010) 11:594-600. doi:10.1038/ni.1885.
    • (2010) Nat Immunol , vol.11 , pp. 594-600
    • Takamatsu, H.1    Takegahara, N.2    Nakagawa, Y.3    Tomura, M.4    Taniguchi, M.5    Friedel, R.H.6
  • 126
    • 10244253876 scopus 로고    scopus 로고
    • CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium
    • doi:10.1182/blood-2004-01-0222
    • Salmi M, Koskinen K, Henttinen T, Elima K, Jalkanen S. CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. Blood (2004) 104:3849-57. doi:10.1182/blood-2004-01-0222.
    • (2004) Blood , vol.104 , pp. 3849-3857
    • Salmi, M.1    Koskinen, K.2    Henttinen, T.3    Elima, K.4    Jalkanen, S.5
  • 127
    • 73249139059 scopus 로고    scopus 로고
    • Clever-1/stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation
    • doi:10.1002/eji.200939896
    • Karikoski M, Irjala H, Maksimow M, Miiluniemi M, Granfors K, Hernesniemi S, et al. Clever-1/stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation. Eur J Immunol (2009) 39:3477-87. doi:10.1002/eji.200939896.
    • (2009) Eur J Immunol , vol.39 , pp. 3477-3487
    • Karikoski, M.1    Irjala, H.2    Maksimow, M.3    Miiluniemi, M.4    Granfors, K.5    Hernesniemi, S.6
  • 128
    • 67649786938 scopus 로고    scopus 로고
    • Influence of the mannose receptor in host immune responses
    • doi:10.1016/j.imbio.2008.11.004
    • Gazi U, Martinez-Pomares L. Influence of the mannose receptor in host immune responses. Immunobiology (2009) 214:554-61. doi:10.1016/j.imbio.2008.11.004.
    • (2009) Immunobiology , vol.214 , pp. 554-561
    • Gazi, U.1    Martinez-Pomares, L.2
  • 129
    • 0035886820 scopus 로고    scopus 로고
    • Mannose receptor is a novel ligand for L-selectin and mediates lymphocyte binding to lymphatic endothelium
    • doi:10.1084/jem.194.8.1033
    • Irjala H, Johansson EL, Grenman R, Alanen K, Salmi M, Jalkanen S. Mannose receptor is a novel ligand for L-selectin and mediates lymphocyte binding to lymphatic endothelium. J Exp Med (2001) 194:1033-42. doi:10.1084/jem.194.8.1033.
    • (2001) J Exp Med , vol.194 , pp. 1033-1042
    • Irjala, H.1    Johansson, E.L.2    Grenman, R.3    Alanen, K.4    Salmi, M.5    Jalkanen, S.6
  • 130
    • 47249109453 scopus 로고    scopus 로고
    • Macrophage mannose receptor on lymphatics controls cell trafficking
    • doi:10.1182/blood-2007-10-118984
    • Marttila-Ichihara F, Turja R, Miiluniemi M, Karikoski M, Maksimow M, Niemela J, et al. Macrophage mannose receptor on lymphatics controls cell trafficking. Blood (2008) 112:64-72. doi:10.1182/blood-2007-10-118984.
    • (2008) Blood , vol.112 , pp. 64-72
    • Marttila-Ichihara, F.1    Turja, R.2    Miiluniemi, M.3    Karikoski, M.4    Maksimow, M.5    Niemela, J.6
  • 131
    • 34249689634 scopus 로고    scopus 로고
    • Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment
    • doi:10.1182/blood-2006-10-053280
    • Amatschek S, Kriehuber E, Bauer W, Reininger B, Meraner P, Wolpl A, et al. Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment. Blood (2007) 109:4777-85. doi:10.1182/blood-2006-10-053280.
    • (2007) Blood , vol.109 , pp. 4777-4785
    • Amatschek, S.1    Kriehuber, E.2    Bauer, W.3    Reininger, B.4    Meraner, P.5    Wolpl, A.6
  • 132
    • 84863206217 scopus 로고    scopus 로고
    • Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation
    • doi:10.1096/fj.12-205278
    • Norder M, Gutierrez MG, Zicari S, Cervi E, Caruso A, Guzman CA. Lymph node-derived lymphatic endothelial cells express functional costimulatory molecules and impair dendritic cell-induced allogenic T-cell proliferation. FASEB J (2012) 26:2835-46. doi:10.1096/fj.12-205278.
    • (2012) FASEB J , vol.26 , pp. 2835-2846
    • Norder, M.1    Gutierrez, M.G.2    Zicari, S.3    Cervi, E.4    Caruso, A.5    Guzman, C.A.6
  • 133
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • doi:10.1084/jem.20092465
    • Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med (2010) 207:681-8. doi:10.1084/jem.20092465.
    • (2010) J Exp Med , vol.207 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3    Qiao, H.4    Rouhani, S.J.5    Ruddell, A.6
  • 134
    • 84870729573 scopus 로고    scopus 로고
    • Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells
    • doi:10.1182/blood-2012-04-427013
    • Tewalt EF, Cohen JN, Rouhani SJ, Guidi CJ, Qiao H, Fahl SP, et al. Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood (2012) 120:4772-82. doi:10.1182/blood-2012-04-427013.
    • (2012) Blood , vol.120 , pp. 4772-4782
    • Tewalt, E.F.1    Cohen, J.N.2    Rouhani, S.J.3    Guidi, C.J.4    Qiao, H.5    Fahl, S.P.6
  • 135
    • 0030990065 scopus 로고    scopus 로고
    • Costimulation, tolerance and ignorance of cytolytic T lymphocytes in immune responses to tumor antigens
    • doi:10.1016/S0024-3205(96)00686-8
    • Melero I, Bach N, Chen L. Costimulation, tolerance and ignorance of cytolytic T lymphocytes in immune responses to tumor antigens. Life Sci (1997) 60:2035-41. doi:10.1016/S0024-3205(96)00686-8.
    • (1997) Life Sci , vol.60 , pp. 2035-2041
    • Melero, I.1    Bach, N.2    Chen, L.3
  • 136
    • 84861116064 scopus 로고    scopus 로고
    • VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics
    • doi:10.1016/j.celrep.2012.01.005
    • Lund AW, Duraes FV, Hirosue S, Raghavan VR, Nembrini C, Thomas SN, et al. VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics. Cell Rep (2012) 1:191-9. doi:10.1016/j.celrep.2012.01.005.
    • (2012) Cell Rep , vol.1 , pp. 191-199
    • Lund, A.W.1    Duraes, F.V.2    Hirosue, S.3    Raghavan, V.R.4    Nembrini, C.5    Thomas, S.N.6
  • 137
    • 84874273601 scopus 로고    scopus 로고
    • Lymphatic endothelial cells-key players in regulation of tolerance and immunity
    • doi:10.3389/fimmu.2012.00305
    • Tewalt EF, Cohen JN, Rouhani SJ, Engelhard VH. Lymphatic endothelial cells-key players in regulation of tolerance and immunity. Front Immunol (2012) 3:305. doi:10.3389/fimmu.2012.00305.
    • (2012) Front Immunol , vol.3 , pp. 305
    • Tewalt, E.F.1    Cohen, J.N.2    Rouhani, S.J.3    Engelhard, V.H.4
  • 138
    • 0036696174 scopus 로고    scopus 로고
    • The immunological synapse: integrins take the stage
    • doi:10.1034/j.1600-065X.2002.18610.x
    • Sims TN, Dustin ML. The immunological synapse: integrins take the stage. Immunol Rev (2002) 186:100-17. doi:10.1034/j.1600-065X.2002.18610.x.
    • (2002) Immunol Rev , vol.186 , pp. 100-117
    • Sims, T.N.1    Dustin, M.L.2
  • 139
    • 68149124237 scopus 로고    scopus 로고
    • Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism
    • doi:10.4049/jimmunol.0802167
    • Podgrabinska S, Kamalu O, Mayer L, Shimaoka M, Snoeck H, Randolph GJ, et al. Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol (2009) 183:1767-79. doi:10.4049/jimmunol.0802167.
    • (2009) J Immunol , vol.183 , pp. 1767-1779
    • Podgrabinska, S.1    Kamalu, O.2    Mayer, L.3    Shimaoka, M.4    Snoeck, H.5    Randolph, G.J.6
  • 140
    • 44849090095 scopus 로고    scopus 로고
    • CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response
    • doi:10.1002/eji.200737800
    • Lippert U, Zachmann K, Ferrari DM, Schwarz H, Brunner E, Mahbub-Ul Latif AH, et al. CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response. Eur J Immunol (2008) 38:1024-32. doi:10.1002/eji.200737800.
    • (2008) Eur J Immunol , vol.38 , pp. 1024-1032
    • Lippert, U.1    Zachmann, K.2    Ferrari, D.M.3    Schwarz, H.4    Brunner, E.5    Mahbub-Ul Latif, A.H.6
  • 141
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • doi:10.1038/nrc3258
    • Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer (2012) 12:265-77. doi:10.1038/nrc3258.
    • (2012) Nat Rev Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 142
    • 80052439234 scopus 로고    scopus 로고
    • Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients
    • doi:10.1158/1078-0432.CCR-11-1261
    • Lesterhuis WJ, De Vries IJ, Schreibelt G, Lambeck AJ, Aarntzen EH, Jacobs JF, et al. Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients. Clin Cancer Res (2011) 17:5725-35. doi:10.1158/1078-0432.CCR-11-1261.
    • (2011) Clin Cancer Res , vol.17 , pp. 5725-5735
    • Lesterhuis, W.J.1    De Vries, I.J.2    Schreibelt, G.3    Lambeck, A.J.4    Aarntzen, E.H.5    Jacobs, J.F.6
  • 143
    • 0037226599 scopus 로고    scopus 로고
    • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
    • De Vries IJ, Krooshoop DJ, Scharenborg NM, Lesterhuis WJ, Diepstra JH, Van Muijen GN, et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res (2003) 63:12-7.
    • (2003) Cancer Res , vol.63 , pp. 12-17
    • De Vries, I.J.1    Krooshoop, D.J.2    Scharenborg, N.M.3    Lesterhuis, W.J.4    Diepstra, J.H.5    Van Muijen, G.N.6
  • 144
    • 27944504770 scopus 로고    scopus 로고
    • Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
    • doi:10.1038/nbt1154
    • de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, Van Krieken JH, Boerman OC, et al. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol (2005) 23:1407-13. doi:10.1038/nbt1154.
    • (2005) Nat Biotechnol , vol.23 , pp. 1407-1413
    • de Vries, I.J.1    Lesterhuis, W.J.2    Barentsz, J.O.3    Verdijk, P.4    Van Krieken, J.H.5    Boerman, O.C.6
  • 145
    • 0345447557 scopus 로고    scopus 로고
    • Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
    • Nair S, Mclaughlin C, Weizer A, Su Z, Boczkowski D, Dannull J, et al. Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol (2003) 171:6275-82.
    • (2003) J Immunol , vol.171 , pp. 6275-6282
    • Nair, S.1    Mclaughlin, C.2    Weizer, A.3    Su, Z.4    Boczkowski, D.5    Dannull, J.6
  • 146
    • 77649163400 scopus 로고    scopus 로고
    • Conditioning of the injection site with CpG enhances the migration of adoptively transferred dendritic cells and endogenous CD8+ T-cell responses
    • doi:10.1097/CJI.0b013e3181b8ef5f
    • Tripp CH, Ebner S, Ratzinger G, Romani N, Stoitzner P. Conditioning of the injection site with CpG enhances the migration of adoptively transferred dendritic cells and endogenous CD8+ T-cell responses. J Immunother (2010) 33:115-25. doi:10.1097/CJI.0b013e3181b8ef5f.
    • (2010) J Immunother , vol.33 , pp. 115-125
    • Tripp, C.H.1    Ebner, S.2    Ratzinger, G.3    Romani, N.4    Stoitzner, P.5
  • 147
    • 29644446061 scopus 로고    scopus 로고
    • The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity
    • Prins RM, Craft N, Bruhn KW, Khan-Farooqi H, Koya RC, Stripecke R, et al. The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity. J Immunol (2006) 176:157-64.
    • (2006) J Immunol , vol.176 , pp. 157-164
    • Prins, R.M.1    Craft, N.2    Bruhn, K.W.3    Khan-Farooqi, H.4    Koya, R.C.5    Stripecke, R.6
  • 148
    • 42049096991 scopus 로고    scopus 로고
    • Type I interferons as vaccine adjuvants against infectious diseases and cancer
    • doi:10.1586/14760584.7.3.373
    • Bracci L, La Sorsa V, Belardelli F, Proietti E. Type I interferons as vaccine adjuvants against infectious diseases and cancer. Expert Rev Vaccines (2008) 7:373-81. doi:10.1586/14760584.7.3.373.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 373-381
    • Bracci, L.1    La Sorsa, V.2    Belardelli, F.3    Proietti, E.4
  • 149
    • 84867911449 scopus 로고    scopus 로고
    • Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism
    • doi:10.4049/jimmunol.1201371
    • Cummings RJ, Gerber SA, Judge JL, Ryan JL, Pentland AP, Lord EM. Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism. J Immunol (2012) 189:4247-57. doi:10.4049/jimmunol.1201371.
    • (2012) J Immunol , vol.189 , pp. 4247-4257
    • Cummings, R.J.1    Gerber, S.A.2    Judge, J.L.3    Ryan, J.L.4    Pentland, A.P.5    Lord, E.M.6
  • 150
    • 84859807493 scopus 로고    scopus 로고
    • Improved efficacy of dendritic cell-based immunotherapy by cutaneous laser illumination
    • doi:10.1158/1078-0432.CCR-11-2654
    • Chen X, Zeng Q, Wu MX. Improved efficacy of dendritic cell-based immunotherapy by cutaneous laser illumination. Clin Cancer Res (2012) 18:2240-9. doi:10.1158/1078-0432.CCR-11-2654.
    • (2012) Clin Cancer Res , vol.18 , pp. 2240-2249
    • Chen, X.1    Zeng, Q.2    Wu, M.X.3
  • 151
    • 82755189230 scopus 로고    scopus 로고
    • Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
    • doi:10.4049/jimmunol.1102209
    • Alfaro C, Perez-Gracia JL, Suarez N, Rodriguez J, Fernandez De Sanmamed M, Sangro B, et al. Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients. J Immunol (2011) 187:6130-42. doi:10.4049/jimmunol.1102209.
    • (2011) J Immunol , vol.187 , pp. 6130-6142
    • Alfaro, C.1    Perez-Gracia, J.L.2    Suarez, N.3    Rodriguez, J.4    Fernandez De Sanmamed, M.5    Sangro, B.6
  • 152
    • 0037103366 scopus 로고    scopus 로고
    • Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
    • doi:10.1182/blood-2001-11-0017
    • Scandella E, Men Y, Gillessen S, Forster R, Groettrup M. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood (2002) 100:1354-61. doi:10.1182/blood-2001-11-0017.
    • (2002) Blood , vol.100 , pp. 1354-1361
    • Scandella, E.1    Men, Y.2    Gillessen, S.3    Forster, R.4    Groettrup, M.5
  • 153
    • 0038240422 scopus 로고    scopus 로고
    • Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
    • doi:10.1038/nm872
    • Kabashima K, Sakata D, Nagamachi M, Miyachi Y, Inaba K, Narumiya S. Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nat Med (2003) 9:744-9. doi:10.1038/nm872.
    • (2003) Nat Med , vol.9 , pp. 744-749
    • Kabashima, K.1    Sakata, D.2    Nagamachi, M.3    Miyachi, Y.4    Inaba, K.5    Narumiya, S.6
  • 154
    • 58149100558 scopus 로고    scopus 로고
    • The lymphatic system in health and disease
    • doi:10.1089/lrb.2008.1008
    • Cueni LN, Detmar M. The lymphatic system in health and disease. Lymphat Res Biol (2008) 6:109-22. doi:10.1089/lrb.2008.1008.
    • (2008) Lymphat Res Biol , vol.6 , pp. 109-122
    • Cueni, L.N.1    Detmar, M.2
  • 155
    • 3843120939 scopus 로고    scopus 로고
    • Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia
    • doi:10.1182/blood-2003-08-2964
    • Kunstfeld R, Hirakawa S, Hong YK, Schacht V, Lange-Asschenfeldt B, Velasco P, et al. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood (2004) 104:1048-57. doi:10.1182/blood-2003-08-2964.
    • (2004) Blood , vol.104 , pp. 1048-1057
    • Kunstfeld, R.1    Hirakawa, S.2    Hong, Y.K.3    Schacht, V.4    Lange-Asschenfeldt, B.5    Velasco, P.6
  • 156
    • 37249060635 scopus 로고    scopus 로고
    • Increased lymphangiogenesis in joints of mice with inflammatory arthritis
    • doi:10.1186/ar2326
    • Zhang Q, Lu Y, Proulx ST, Guo R, Yao Z, Schwarz EM, et al. Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis Res Ther (2007) 9:R118. doi:10.1186/ar2326.
    • (2007) Arthritis Res Ther , vol.9
    • Zhang, Q.1    Lu, Y.2    Proulx, S.T.3    Guo, R.4    Yao, Z.5    Schwarz, E.M.6
  • 157
    • 79959657080 scopus 로고    scopus 로고
    • Targeting lymphangiogenesis after islet transplantation prolongs isletallograft survival
    • doi:10.1097/TP.0b013e31821d2661
    • Yin N, Zhang N, Xu J, Shi Q, Ding Y, Bromberg JS. Targeting lymphangiogenesis after islet transplantation prolongs isletallograft survival. Transplantation (2011) 92:25-30. doi:10.1097/TP.0b013e31821d2661.
    • (2011) Transplantation , vol.92 , pp. 25-30
    • Yin, N.1    Zhang, N.2    Xu, J.3    Shi, Q.4    Ding, Y.5    Bromberg, J.S.6
  • 158
    • 4043049430 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity
    • doi:10.1038/nm1078
    • Chen L, Hamrah P, Cursiefen C, Zhang Q, Pytowski B, Streilein JW, et al. Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. Nat Med (2004) 10:813-5. doi:10.1038/nm1078.
    • (2004) Nat Med , vol.10 , pp. 813-815
    • Chen, L.1    Hamrah, P.2    Cursiefen, C.3    Zhang, Q.4    Pytowski, B.5    Streilein, J.W.6
  • 159
    • 77950224116 scopus 로고    scopus 로고
    • Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts
    • doi:10.1161/CIRCULATIONAHA.109.910703
    • Nykanen AI, Sandelin H, Krebs R, Keranen MA, Tuuminen R, Karpanen T, et al. Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts. Circulation (2010) 121:1413-22. doi:10.1161/CIRCULATIONAHA.109.910703.
    • (2010) Circulation , vol.121 , pp. 1413-1422
    • Nykanen, A.I.1    Sandelin, H.2    Krebs, R.3    Keranen, M.A.4    Tuuminen, R.5    Karpanen, T.6
  • 160
    • 0037223254 scopus 로고    scopus 로고
    • Antagonist of secondary lymphoid-tissue chemokine (CCR ligand 21) prevents the development of chronic graft-versus-host disease in mice
    • Sasaki M, Hasegawa H, Kohno M, Inoue A, Ito MR, Fujita S. Antagonist of secondary lymphoid-tissue chemokine (CCR ligand 21) prevents the development of chronic graft-versus-host disease in mice. J Immunol (2003) 170:588-96.
    • (2003) J Immunol , vol.170 , pp. 588-596
    • Sasaki, M.1    Hasegawa, H.2    Kohno, M.3    Inoue, A.4    Ito, M.R.5    Fujita, S.6
  • 161
    • 61949276292 scopus 로고    scopus 로고
    • JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling
    • doi:10.1242/jcs.037127
    • Cera MR, Fabbri M, Molendini C, Corada M, Orsenigo F, Rehberg M, et al. JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling. J Cell Sci (2009) 122:268-77. doi:10.1242/jcs.037127.
    • (2009) J Cell Sci , vol.122 , pp. 268-277
    • Cera, M.R.1    Fabbri, M.2    Molendini, C.3    Corada, M.4    Orsenigo, F.5    Rehberg, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.