Cutting edge: Scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6

Journal of Immunology

Volumn 170, Issue 5, 2003, Pages 2279-2282

  Fra, Anna M ^a   Locati, Massimo ^b   Otero, Karel ^c   Sironi, Marina ^c   Signorelli, Paola ^b   Massardi, Maria L ^a   Gobbi, Marco ^c   Vecchi, Annunciata ^c   Sozzani, Silvano ^c   Mantovani, Alberto ^b,c  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR D6; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; HUMAN; IMMUNOREGULATION; INFLAMMATION; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RECEPTOR BINDING;

EID: 0345505649     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.5.2279     Document Type: Article

References (20)

1. Mantovani, A., and S. Sozzani. 2000. Chemokines. In The Cyrokine Network. F. Balkwill, ed. Oxford University, Oxford, p. 103.
2. Rollins, B.J. 1997. Chemokines. Blood 90:909.
3. Zlomik, A., and O. Yoshie. 2000. Chemokines: a new classification system and their role in immunity. Immunity 12:121.
4. Murphy, P. M., M. Baggiolini, I. F. Charo, C.A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power. 2000. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52:145.
5. Horuk, R., A. Martin, J. Hesselgesser, T. Hadley, Z. H. Lu, Z. X. Wang, and S. C. Peiper. 1996. The Dully antigen receptor for chemokines: structural analysis and expression in the brain. J Leukocyte Biol. 59:29.
6. Nibbs, R. J., S. M. Wylie, J. Yang, N. R. Landau, and G. J. Graham. 1997. Cloning and characterization of a novel promiscuous human β- chemokine receptor D6. J. Biol Chem. 272:32078.
7. Mantovani, A., M. Locati, A. Vecchi, S. Sozzani, and P. Allavena. 2001. Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol. 22:328
8. Bonini, J. A., S. K. Martin, F. Dralyuk, M. W. Roe, L. H. Philipson, and D. F. Steiner. 1997. Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-3. DNA Cell Biol 16:1249.
9. Nibbs, R. J., E. Kriehuber, P. D. Ponath, D. Parent, S. Qin, J. D. Campbell, A. Henderson, D. Kerjaschki, D. Maurer, G. J. Graham, and A. Rot. 2001. The β-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am. J. Pathol. 158:867.
10. Mancardi, S., G. Stanta, N. Dusetti, M. Bestagno, L. Jussila, M. Zweyer, G. Lunazzi, D. Dumont, K. Alitalo, and O. R. Burrone. 1999. Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant. Exp. Cell Res. 246:368.
11. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:3099.
12. Middleton, J., S. Nell, J. Wintie, I. Clark-Lewis, H. Moore, C. Lam, M. Auer, E. Hub, and A. Rot. 1997. Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 91:385.
13. Colotta, F., F. Re, M. Muzio, R. Bertini, N. Polentarutti, M. Sironi, J. G. Girl, S. K. Dower, J. E. Sims, and A. Mantovani. 1993. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 261:472.
14. D'Amico, G., G. Frascaroli, G. Bianchi, P. Transidico, A. Doni, A. Vecchi, S. Sozzani, P. Allavena, and A. Mantovani. 2000. Uncoupling of inflammatory chemoklne receptors by IL-10: generation of functional decoys. Nat. Immunol. 1:387
15. Thelen, M. 2001. Dancing to the tune ofchemokines. Nat. Immunol. 2:129.
16. Fraile-Ramos, A., T. N. Kledal, A. Pelchen-Matthews, K. Bowers, T. W. Schwartz, and M. Marsh. 2001. The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling. Mol. Biol Cell 12: 1737.
17. Bodaghi, B., T. R. Jones, D. Zipeto, C. Vita, L. Sun, L. Laurent, F. Arenzana-Seisdedos, J. L. Virelizier, and S. Michelson. 1998. Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells. J. Exp. Med. 188:855.
18. Casarosa, P., R. A. Bakker, D. Verzijl, M. Naris, H. Timmerman, R. Leurs, and M. J. Smit. 2001. Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28. J. Biol Chem. 276:1133.
19. Palframan, R. T., S. Jung, G. Cheng, W. Weninger, Y. Luo, M. Dorf, D. R. Littman, B. J. Rollins, H. Zweerink, A. Rot, and U. H. yon Andrian. 2001. Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J. Exp. Med. 194:1361.
20. Janatpour, M. J., S. Hudak, M. Sathe, J. D. Sedgwick, and L. M. McEvoy. 2001. Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment, J. Exp. Med. 194:1375.