-
1
-
-
0019012442
-
Vaccine adjuvants
-
Edelman R. Vaccine adjuvants. Rev. Infect. Dis. 2(3), 370-383 (1980).
-
(1980)
Rev. Infect. Dis
, vol.2
, Issue.3
, pp. 370-383
-
-
Edelman, R.1
-
2
-
-
0032738026
-
Advances in vaccine adjuvants
-
Singh M, O'Hagan D. Advances in vaccine adjuvants. Nat. Biotechnol. 17(11), 1075-1081 (1999).
-
(1999)
Nat. Biotechnol
, vol.17
, Issue.11
, pp. 1075-1081
-
-
Singh, M.1
O'Hagan, D.2
-
3
-
-
34247169514
-
Vaccine adjuvants revisited
-
Aguilar JC, Rodriguez EG. Vaccine adjuvants revisited. Vaccine 25(19), 3752-3762 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.19
, pp. 3752-3762
-
-
Aguilar, J.C.1
Rodriguez, E.G.2
-
4
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5(10), 987-995 (2004).
-
(2004)
Nat. Immunol
, vol.5
, Issue.10
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
5
-
-
0029557590
-
Present status of the use of cytokines as adjuvants with vaccines to protect against infectious diseases
-
Lin R, Tarr PE, Jones TC. Present status of the use of cytokines as adjuvants with vaccines to protect against infectious diseases. Clin. Infect. Dis. 21(6), 1439-1449 (1995).
-
(1995)
Clin. Infect. Dis
, vol.21
, Issue.6
, pp. 1439-1449
-
-
Lin, R.1
Tarr, P.E.2
Jones, T.C.3
-
6
-
-
34347231940
-
Interferon, a growing cytokine family: 50 years of interferon research
-
Chelbi-Alix MK, Wietzerbin J. Interferon, a growing cytokine family: 50 years of interferon research. Biochimie 89(6-7), 713-778 (2007).
-
(2007)
Biochimie
, vol.89
, Issue.6-7
, pp. 713-778
-
-
Chelbi-Alix, M.K.1
Wietzerbin, J.2
-
7
-
-
1842298345
-
Injection of mice with antibody to interferon renders peritoneal macrophages permissive for vesicular stomatitis virus and encephalomyocarditis virus
-
Belardelli F, Vignaux F, Proietti E, Gresser I. Injection of mice with antibody to interferon renders peritoneal macrophages permissive for vesicular stomatitis virus and encephalomyocarditis virus. Proc. Natl Acad. Sci. USA 81(2), 602-606 (1984).
-
(1984)
Proc. Natl Acad. Sci. USA
, vol.81
, Issue.2
, pp. 602-606
-
-
Belardelli, F.1
Vignaux, F.2
Proietti, E.3
Gresser, I.4
-
9
-
-
12344294498
-
Human interferons α, β and ω
-
Bekisz J, Schmeisser H, Hernandez J, Goldman ND, Zoon KC. Human interferons α, β and ω. Growth Factors 22(4), 243-251 (2004).
-
(2004)
Growth Factors
, vol.22
, Issue.4
, pp. 243-251
-
-
Bekisz, J.1
Schmeisser, H.2
Hernandez, J.3
Goldman, N.D.4
Zoon, K.C.5
-
10
-
-
0032191176
-
Role of early cytokines, including α and β interferons (IFN-α/β), in innate and adaptive immune responses to viral infections
-
Biron CA. Role of early cytokines, including α and β interferons (IFN-α/β), in innate and adaptive immune responses to viral infections. Semin. Immunol. 10(5), 383-390 (1998).
-
(1998)
Semin. Immunol
, vol.10
, Issue.5
, pp. 383-390
-
-
Biron, C.A.1
-
11
-
-
0034954034
-
Interferons α and β as immune regulators - a new look
-
Biron CA. Interferons α and β as immune regulators - a new look. Immunity 14(6), 661-664 (2001).
-
(2001)
Immunity
, vol.14
, Issue.6
, pp. 661-664
-
-
Biron, C.A.1
-
12
-
-
0030221837
-
The neglected role of type I interferon in the T-cell response: Implications for its clinical use
-
Belardelli F, Gresser I. The neglected role of type I interferon in the T-cell response: implications for its clinical use. Immunol. Today 17(8), 369-372 (1996).
-
(1996)
Immunol. Today
, vol.17
, Issue.8
, pp. 369-372
-
-
Belardelli, F.1
Gresser, I.2
-
13
-
-
0142092614
-
+ T cells stimulated by virus-induced type I interferon
-
+ T cells stimulated by virus-induced type I interferon. Nat. Immunol. 4(10), 1009-1015 (2003).
-
(2003)
Nat. Immunol
, vol.4
, Issue.10
, pp. 1009-1015
-
-
Le Bon, A.1
Etchart, N.2
Rossmann, C.3
-
14
-
-
0029671118
-
Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-1 development
-
Wenner CA, Guler ML, Macatonia SE, O'Garra A, Murphy KM. Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-1 development. J. Immunol. 156(4), 1442-1447 (1996).
-
(1996)
J. Immunol
, vol.156
, Issue.4
, pp. 1442-1447
-
-
Wenner, C.A.1
Guler, M.L.2
Macatonia, S.E.3
O'Garra, A.4
Murphy, K.M.5
-
15
-
-
0034699775
-
Cytokine-modulated regulation of helper T cell populations
-
Yates A, Bergmann C, Van Hemmen JL, Stark J, Callard R. Cytokine-modulated regulation of helper T cell populations. J. Theor. Biol. 206(4), 539-560 (2000).
-
(2000)
J. Theor. Biol
, vol.206
, Issue.4
, pp. 539-560
-
-
Yates, A.1
Bergmann, C.2
Van Hemmen, J.L.3
Stark, J.4
Callard, R.5
-
16
-
-
0035030376
-
-
Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14(4), 461-470 (2001). •• Demonstrates that type I interferons (IFNs) possess strong adjuvant activity, inducing long-term antibody production and immunological memory against a poorly immunogenic antigen. Moreover, it shows that dendritic cells (DCs) are the cell type mediating the adjuvant effect of type I IFNs in vivo.
-
Le Bon A, Schiavoni G, D'Agostino G, Gresser I, Belardelli F, Tough DF. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14(4), 461-470 (2001). •• Demonstrates that type I interferons (IFNs) possess strong adjuvant activity, inducing long-term antibody production and immunological memory against a poorly immunogenic antigen. Moreover, it shows that dendritic cells (DCs) are the cell type mediating the adjuvant effect of type I IFNs in vivo.
-
-
-
-
17
-
-
0036644485
-
Type I IFN as a natural adjuvant for a protective immune response: Lessons from the influenza vaccine model
-
Proietti E, Bracci L, Puzelli S et al. Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model. J. Immunol. 169(1), 375-383 (2002).
-
(2002)
J. Immunol
, vol.169
, Issue.1
, pp. 375-383
-
-
Proietti, E.1
Bracci, L.2
Puzelli, S.3
-
18
-
-
0034669955
-
IFN-γ and IFN-α posttranscriptionally down-regulate the IL-4-induced IL-4 receptor gene expression
-
So EY, Park HH, Lee CE. IFN-γ and IFN-α posttranscriptionally down-regulate the IL-4-induced IL-4 receptor gene expression. J. Immunol. 165(10), 5472-5479 (2000).
-
(2000)
J. Immunol
, vol.165
, Issue.10
, pp. 5472-5479
-
-
So, E.Y.1
Park, H.H.2
Lee, C.E.3
-
19
-
-
0027173530
-
IFN induction and associated changes in splenic leukocyte distribution
-
Ishikawa R, Biron CA. IFN induction and associated changes in splenic leukocyte distribution. J. Immunol. 150(9), 3713-3727 (1993).
-
(1993)
J. Immunol
, vol.150
, Issue.9
, pp. 3713-3727
-
-
Ishikawa, R.1
Biron, C.A.2
-
20
-
-
34347250432
-
The role of type I interferon production by dendritic cells in host defense
-
Fitzgerald-Bocarsly P, Feng D. The role of type I interferon production by dendritic cells in host defense. Biochimie 89(6-7), 843-855 (2007).
-
(2007)
Biochimie
, vol.89
, Issue.6-7
, pp. 843-855
-
-
Fitzgerald-Bocarsly, P.1
Feng, D.2
-
21
-
-
0034658658
-
Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice
-
Santini SM, Lapenta C, Logozzi M et al. Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J. Exp. Med. 191(10), 1777-1788 (2000).
-
(2000)
J. Exp. Med
, vol.191
, Issue.10
, pp. 1777-1788
-
-
Santini, S.M.1
Lapenta, C.2
Logozzi, M.3
-
22
-
-
0141703238
-
Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
-
Honda K, Sakaguchi S, Nakajima C et al. Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc. Natl Acad. Sci. USA 100(19), 10872-10877 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.19
, pp. 10872-10877
-
-
Honda, K.1
Sakaguchi, S.2
Nakajima, C.3
-
23
-
-
0032695108
-
Natural adjuvants: Endogenous activators of dendritic cells
-
Represents the first evidence that signals from virally infected or dying cells can function as adjuvants to stimulate a primary immune responses through DC activation, ••
-
Gallucci S, Lolkema M, Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 5(11), 1249-1255 (1999). •• Represents the first evidence that signals from virally infected or dying cells can function as adjuvants to stimulate a primary immune responses through DC activation.
-
(1999)
Nat. Med
, vol.5
, Issue.11
, pp. 1249-1255
-
-
Gallucci, S.1
Lolkema, M.2
Matzinger, P.3
-
24
-
-
0032529213
-
Type I IFNs enhance the terminal differentiation of dendritic cells
-
Luft T, Pang KC, Thomas E et al. Type I IFNs enhance the terminal differentiation of dendritic cells. J. Immunol. 161(4), 1947-1953 (1998).
-
(1998)
J. Immunol
, vol.161
, Issue.4
, pp. 1947-1953
-
-
Luft, T.1
Pang, K.C.2
Thomas, E.3
-
25
-
-
34447505084
-
Toll-like receptors and type I interferons
-
Overview on Toll-like receptor (TLR)-dependent and independent induction of type I IFNs, •
-
Uematsu S, Akira S. Toll-like receptors and type I interferons. J. Biol. Chem. 282(21), 15319-15323 (2007). • Overview on Toll-like receptor (TLR)-dependent and independent induction of type I IFNs.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.21
, pp. 15319-15323
-
-
Uematsu, S.1
Akira, S.2
-
26
-
-
34250331531
-
-
Guy B. The perfect mix: recent progress in adjuvant research. Nat. Rev. Microbiol. 5(7), 505-517 (2007). • Gives an overview on the advances in adjuvant research.
-
Guy B. The perfect mix: recent progress in adjuvant research. Nat. Rev. Microbiol. 5(7), 505-517 (2007). • Gives an overview on the advances in adjuvant research.
-
-
-
-
27
-
-
13544263585
-
IFN-α regulates TLR-dependent gene expression of IFN-α, IFN-β, IL-28, and IL-29
-
Siren J, Pirhonen J, Julkunen I, Matikainen S. IFN-α regulates TLR-dependent gene expression of IFN-α, IFN-β, IL-28, and IL-29. J. Immunol. 174(4), 1932-1937 (2005).
-
(2005)
J. Immunol
, vol.174
, Issue.4
, pp. 1932-1937
-
-
Siren, J.1
Pirhonen, J.2
Julkunen, I.3
Matikainen, S.4
-
28
-
-
0141923686
-
Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
-
Lore K, Betts MR, Brenchley JM et al. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses. J. Immunol. 171(8), 4320-4328 (2003).
-
(2003)
J. Immunol
, vol.171
, Issue.8
, pp. 4320-4328
-
-
Lore, K.1
Betts, M.R.2
Brenchley, J.M.3
-
30
-
-
0035423390
-
IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation
-
Mattei F, Schiavoni G, Belardelli F, Tough DF. IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation. J. Immunol. 167(3), 1179-1187 (2001).
-
(2001)
J. Immunol
, vol.167
, Issue.3
, pp. 1179-1187
-
-
Mattei, F.1
Schiavoni, G.2
Belardelli, F.3
Tough, D.F.4
-
31
-
-
17844384773
-
Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: Evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity
-
2005
-
Salem ML, Kadima AN, Cole DJ, Gillanders WE. Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J. Immunother (1997). 28(3), 220-228 (2005).
-
(1997)
J. Immunother
, vol.28
, Issue.3
, pp. 220-228
-
-
Salem, M.L.1
Kadima, A.N.2
Cole, D.J.3
Gillanders, W.E.4
-
32
-
-
33744521498
-
+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu
-
+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu. Vaccine 24(24), 5119-5132 (2006).
-
(2006)
Vaccine
, vol.24
, Issue.24
, pp. 5119-5132
-
-
Salem, M.L.1
El-Naggar, S.A.2
Kadima, A.3
Gillanders, W.E.4
Cole, D.J.5
-
33
-
-
9444229988
-
-
Durand V, Wong SY, Tough DF, Le Bon A. Shaping of adaptive immune responses to soluble proteins by TLR agonists: a role for IFN-α/β. Immunol. Cell Biol. 82(6), 596-602 (2004). •• Comprehensive study on the impact of TLR stimulation on the outcome of adaptive immune responses during immunization in vivo.
-
Durand V, Wong SY, Tough DF, Le Bon A. Shaping of adaptive immune responses to soluble proteins by TLR agonists: a role for IFN-α/β. Immunol. Cell Biol. 82(6), 596-602 (2004). •• Comprehensive study on the impact of TLR stimulation on the outcome of adaptive immune responses during immunization in vivo.
-
-
-
-
34
-
-
33750286550
-
Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN
-
McBride S, Hoebe K, Georgel P, Janssen E. Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN. J. Immunol. 177(9), 6122-6128 (2006).
-
(2006)
J. Immunol
, vol.177
, Issue.9
, pp. 6122-6128
-
-
McBride, S.1
Hoebe, K.2
Georgel, P.3
Janssen, E.4
-
35
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5(7), 730-737 (2004).
-
(2004)
Nat. Immunol
, vol.5
, Issue.7
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
-
36
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 175(5), 2851-2858 (2005).
-
(2005)
J. Immunol
, vol.175
, Issue.5
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
-
37
-
-
0037154176
-
Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
-
Kang DC, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, Fisher PB. Mda-5: an interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc. Natl Acad. Sci. USA 99(2), 637-642 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.2
, pp. 637-642
-
-
Kang, D.C.1
Gopalkrishnan, R.V.2
Wu, Q.3
Jankowsky, E.4
Pyle, A.M.5
Fisher, P.B.6
-
38
-
-
33744791510
-
Essential role of Mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
-
Gitlin L, Barchet W, Gilfillan S et al. Essential role of Mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl Acad. Sci. USA 103(22), 8459-8464 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.22
, pp. 8459-8464
-
-
Gitlin, L.1
Barchet, W.2
Gilfillan, S.3
-
39
-
-
33750433224
-
Immunostimulatory combinations: Designing the next generation of vaccine adjuvants
-
Kornbluth RS, Stone GW. Immunostimulatory combinations: designing the next generation of vaccine adjuvants. J. Leukoc. Biol. 80(5), 1084-1102 (2006).
-
(2006)
J. Leukoc. Biol
, vol.80
, Issue.5
, pp. 1084-1102
-
-
Kornbluth, R.S.1
Stone, G.W.2
-
40
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle S, Vaidya S, O'Connell R et al. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17(3), 251-263 (2002).
-
(2002)
Immunity
, vol.17
, Issue.3
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
-
41
-
-
0141670818
-
The interferon in TLR signaling: More than just antiviral
-
Hertzog PJ, O'Neill LA, Hamilton JA. The interferon in TLR signaling: more than just antiviral. Trends Immunol. 24(10), 534-539 (2003).
-
(2003)
Trends Immunol
, vol.24
, Issue.10
, pp. 534-539
-
-
Hertzog, P.J.1
O'Neill, L.A.2
Hamilton, J.A.3
-
42
-
-
0030001830
-
Endogenous IFN-α/β suppresses colony-stimulating factor (CSF)-1-stimulated macrophage DNA synthesis and mediates inhibitory effects of lipopolysaccharide and TNF-α
-
Hamilton JA, Whitty GA, Kola I, Hertzog PJ. Endogenous IFN-α/β suppresses colony-stimulating factor (CSF)-1-stimulated macrophage DNA synthesis and mediates inhibitory effects of lipopolysaccharide and TNF-α. J. Immunol. 156(7), 2553-2557 (1996).
-
(1996)
J. Immunol
, vol.156
, Issue.7
, pp. 2553-2557
-
-
Hamilton, J.A.1
Whitty, G.A.2
Kola, I.3
Hertzog, P.J.4
-
43
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H et al. Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303(5663), 1526-1529 (2004).
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
-
44
-
-
12444341806
-
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
-
Gorden KB, Gorski KS, Gibson SJ et al. Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. J. Immunol. 174(3), 1259-1268 (2005).
-
(2005)
J. Immunol
, vol.174
, Issue.3
, pp. 1259-1268
-
-
Gorden, K.B.1
Gorski, K.S.2
Gibson, S.J.3
-
45
-
-
0033540341
-
Modulation of Th1 and Th2 cytokine production with the immune response modifiers, R-848 and imiquimod
-
Wagner TL, Ahonen CL, Couture AM et al. Modulation of Th1 and Th2 cytokine production with the immune response modifiers, R-848 and imiquimod. Cell. Immunol. 191(1), 10-19 (1999).
-
(1999)
Cell. Immunol
, vol.191
, Issue.1
, pp. 10-19
-
-
Wagner, T.L.1
Ahonen, C.L.2
Couture, A.M.3
-
46
-
-
0033775777
-
Adjuvant activities of immune response modifier R-848: Comparison with CpG ODN
-
Vasilakos JP, Smith RM, Gibson SJ et al. Adjuvant activities of immune response modifier R-848: comparison with CpG ODN. Cell. Immunol. 204(1), 64-74 (2000).
-
(2000)
Cell. Immunol
, vol.204
, Issue.1
, pp. 64-74
-
-
Vasilakos, J.P.1
Smith, R.M.2
Gibson, S.J.3
-
48
-
-
0021256125
-
-
Tokunaga T, Yamamoto H, Shimada S et al. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity. J. Natl. Cancer Inst. 72(4), 955-962 (1984).
-
Tokunaga T, Yamamoto H, Shimada S et al. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity. J. Natl. Cancer Inst. 72(4), 955-962 (1984).
-
-
-
-
49
-
-
0037093861
-
+ T lymphocytes by immunostimulatory DNA-based vaccines
-
+ T lymphocytes by immunostimulatory DNA-based vaccines. J. Immunol. 168(10), 4907-4913 (2002).
-
(2002)
J. Immunol
, vol.168
, Issue.10
, pp. 4907-4913
-
-
Cho, H.J.1
Hayashi, T.2
Datta, S.K.3
-
50
-
-
33644667700
-
An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen
-
Wakita D, Chamoto K, Zhang Y et al. An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen. Int. Immunol. 18(3), 425-434 (2006).
-
(2006)
Int. Immunol
, vol.18
, Issue.3
, pp. 425-434
-
-
Wakita, D.1
Chamoto, K.2
Zhang, Y.3
-
51
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, Wang Z, Choi MK et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448(7152), 501-505 (2007).
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
-
52
-
-
0037471386
-
Super-activated interferon-regulatory factors can enhance plasmid immunization
-
Bramson JL, Dayball K, Hall JR et al. Super-activated interferon-regulatory factors can enhance plasmid immunization. Vaccine 21(13-14), 1363-1370 (2003).
-
(2003)
Vaccine
, vol.21
, Issue.13-14
, pp. 1363-1370
-
-
Bramson, J.L.1
Dayball, K.2
Hall, J.R.3
-
53
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction
-
Sato M, Suemori H, Hata N et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction. Immunity 13(4), 539-548 (2000).
-
(2000)
Immunity
, vol.13
, Issue.4
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
-
54
-
-
0036284363
-
Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors
-
Sasaki S, Amara RR, Yeow WS, Pitha PM, Robinson HL. Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors. J. Virol. 76(13), 6652-6659 (2002).
-
(2002)
J. Virol
, vol.76
, Issue.13
, pp. 6652-6659
-
-
Sasaki, S.1
Amara, R.R.2
Yeow, W.S.3
Pitha, P.M.4
Robinson, H.L.5
-
55
-
-
0033941331
-
Gene therapy of cancer with interferon: Lessons from tumor models and perspectives for clinical applications
-
Ferrantini M, Belardelli F. Gene therapy of cancer with interferon: lessons from tumor models and perspectives for clinical applications. Semin. Cancer Biol. 10(2), 145-157 (2000).
-
(2000)
Semin. Cancer Biol
, vol.10
, Issue.2
, pp. 145-157
-
-
Ferrantini, M.1
Belardelli, F.2
-
56
-
-
33645214607
-
Adjuvant activity of interferon α: Mechanism(s) of action
-
Tovey MG, Lallemand C, Meritet JF, Maury C. Adjuvant activity of interferon α: mechanism(s) of action. Vaccine 24(Suppl. 2), 46-47 (2006).
-
(2006)
Vaccine
, vol.24
, Issue.SUPPL. 2
, pp. 46-47
-
-
Tovey, M.G.1
Lallemand, C.2
Meritet, J.F.3
Maury, C.4
-
57
-
-
34250172713
-
α interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response
-
Cheng G, Zhao X, Yan W et al. α interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response. Vaccine 25(28), 5199-5208 (2007).
-
(2007)
Vaccine
, vol.25
, Issue.28
, pp. 5199-5208
-
-
Cheng, G.1
Zhao, X.2
Yan, W.3
-
58
-
-
0036772786
-
Coimmunisation with type I IFN genes enhances protective immunity against cytomegalovirus and myocarditis in gB DNA-vaccinated mice
-
Cull VS, Broomfield S, Bartlett EJ, Brekalo NL, James CM. Coimmunisation with type I IFN genes enhances protective immunity against cytomegalovirus and myocarditis in gB DNA-vaccinated mice. Gene Ther. 9(20), 1369-1378 (2002).
-
(2002)
Gene Ther
, vol.9
, Issue.20
, pp. 1369-1378
-
-
Cull, V.S.1
Broomfield, S.2
Bartlett, E.J.3
Brekalo, N.L.4
James, C.M.5
-
59
-
-
34548188548
-
Experimental study of the efficacy of combined use of cancer vaccine and interferon
-
Potebnya GP, Kudryavets YY, Lisovenko GS et al. Experimental study of the efficacy of combined use of cancer vaccine and interferon. Exp. Oncol. 29(2), 102-105 (2007).
-
(2007)
Exp. Oncol
, vol.29
, Issue.2
, pp. 102-105
-
-
Potebnya, G.P.1
Kudryavets, Y.Y.2
Lisovenko, G.S.3
-
60
-
-
16844386543
-
Administration of IFN-α enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell Vaccine
-
Prell RA, Li B, Lin JM, VanRoey M, Jooss K. Administration of IFN-α enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell Vaccine Cancer Res. 65(6), 2449-2456 (2005).
-
(2005)
Cancer Res
, vol.65
, Issue.6
, pp. 2449-2456
-
-
Prell, R.A.1
Li, B.2
Lin, J.M.3
VanRoey, M.4
Jooss, K.5
-
61
-
-
0021257131
-
Interferon as an adjuvant for hepatitis B vaccination in non- and low-responder populations
-
Grob PJ, Joller-Jemelka HI, Binswanger U, Zaruba K, Descoeudres C, Fernex M. Interferon as an adjuvant for hepatitis B vaccination in non- and low-responder populations. Eur. J. Clin. Microbiol. 3(3), 195-198 (1984).
-
(1984)
Eur. J. Clin. Microbiol
, vol.3
, Issue.3
, pp. 195-198
-
-
Grob, P.J.1
Joller-Jemelka, H.I.2
Binswanger, U.3
Zaruba, K.4
Descoeudres, C.5
Fernex, M.6
-
62
-
-
0028222854
-
Randomized comparative trial of interferon-α versus placebo in hepatitis B vaccine non-responders and hyporesponders
-
Goldwater PN. Randomized comparative trial of interferon-α versus placebo in hepatitis B vaccine non-responders and hyporesponders. Vaccine 12(5), 410-414 (1994).
-
(1994)
Vaccine
, vol.12
, Issue.5
, pp. 410-414
-
-
Goldwater, P.N.1
-
63
-
-
39149107091
-
Evaluation of the effects of human leukocyte IFN-α on the immune response to the HBV vaccine in healthy unvaccinated individuals
-
Rizza P, Capone I, Urbani F et al. Evaluation of the effects of human leukocyte IFN-α on the immune response to the HBV vaccine in healthy unvaccinated individuals. Vaccine 26(8), 1038-1049 (2008).
-
(2008)
Vaccine
, vol.26
, Issue.8
, pp. 1038-1049
-
-
Rizza, P.1
Capone, I.2
Urbani, F.3
-
64
-
-
33646400810
-
+ T cells and monocyte/dendritic cell precursors
-
+ T cells and monocyte/dendritic cell precursors. Cancer Res. 66(9), 4943-4951 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.9
, pp. 4943-4951
-
-
Di Pucchio, T.1
Pilla, L.2
Capone, I.3
-
65
-
-
0038316325
-
Anatomical basis of tolerance and immunity to intestinal antigens
-
Mowat AM. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3(4), 331-341 (2003).
-
(2003)
Nat. Rev. Immunol
, vol.3
, Issue.4
, pp. 331-341
-
-
Mowat, A.M.1
-
66
-
-
33645821879
-
Mucosal delivery of vaccine antigens and its advantages in pediatrics
-
De Magistris MT. Mucosal delivery of vaccine antigens and its advantages in pediatrics. Adv. Drug Deliv. Rev. 58(1), 52-67 (2006).
-
(2006)
Adv. Drug Deliv. Rev
, vol.58
, Issue.1
, pp. 52-67
-
-
De Magistris, M.T.1
-
67
-
-
14744303986
-
Mucosal adjuvants
-
Freytag LC, Clements JD. Mucosal adjuvants. Vaccine 23(15), 1804-1813 (2005).
-
(2005)
Vaccine
, vol.23
, Issue.15
, pp. 1804-1813
-
-
Freytag, L.C.1
Clements, J.D.2
-
68
-
-
0034809011
-
Effect of oromucosal administration of IFN-α on allergic sensitization and the hypersensitive inflammatory response in animals sensitized to ragweed pollen
-
Meritet JF, Maury C, Tovey MG. Effect of oromucosal administration of IFN-α on allergic sensitization and the hypersensitive inflammatory response in animals sensitized to ragweed pollen. J. Interferon Cytokine Res. 21(8), 583-593 (2001).
-
(2001)
J. Interferon Cytokine Res
, vol.21
, Issue.8
, pp. 583-593
-
-
Meritet, J.F.1
Maury, C.2
Tovey, M.G.3
-
69
-
-
16244389282
-
Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level
-
Evaluates the mechanisms responsible for the adjuvant effect of type I IFNs at mucosal level, ••
-
Bracci L, Canini I, Puzelli S et al. Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level. Vaccine 23(23), 2994-3004 (2005). •• Evaluates the mechanisms responsible for the adjuvant effect of type I IFNs at mucosal level.
-
(2005)
Vaccine
, vol.23
, Issue.23
, pp. 2994-3004
-
-
Bracci, L.1
Canini, I.2
Puzelli, S.3
-
70
-
-
34347240351
-
The antitumor effects of interferon: A personal history
-
Gresser I. The antitumor effects of interferon: a personal history. Biochimie 89(6-7), 723-728 (2007).
-
(2007)
Biochimie
, vol.89
, Issue.6-7
, pp. 723-728
-
-
Gresser, I.1
-
71
-
-
0016199101
-
Suppressive effect of interferon on the humoral immune response to sheep red blood cells in mice
-
Brodeur BR, Merigan TC. Suppressive effect of interferon on the humoral immune response to sheep red blood cells in mice. J. Immunol. 113(4), 1319-1325 (1974).
-
(1974)
J. Immunol
, vol.113
, Issue.4
, pp. 1319-1325
-
-
Brodeur, B.R.1
Merigan, T.C.2
-
72
-
-
0034231339
-
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
-
Farrar JD, Smith JD, Murphy TL, Leung S, Stark GR, Murphy KM. Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nat. Immunol. 1(1), 65-69 (2000).
-
(2000)
Nat. Immunol
, vol.1
, Issue.1
, pp. 65-69
-
-
Farrar, J.D.1
Smith, J.D.2
Murphy, T.L.3
Leung, S.4
Stark, G.R.5
Murphy, K.M.6
-
73
-
-
34347366358
-
Dendritic cells and interferon-mediated autoimmunity
-
Gottenberg JE, Chiocchia G. Dendritic cells and interferon-mediated autoimmunity. Biochimie 89(6-7), 856-871 (2007).
-
(2007)
Biochimie
, vol.89
, Issue.6-7
, pp. 856-871
-
-
Gottenberg, J.E.1
Chiocchia, G.2
-
74
-
-
34248204110
-
DC-based cancer vaccines
-
Gilboa E. DC-based cancer vaccines. J. Clin. Invest. 117(5), 1195-1203 (2007).
-
(2007)
J. Clin. Invest
, vol.117
, Issue.5
, pp. 1195-1203
-
-
Gilboa, E.1
|