Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells

Nature Medicine

Volumn 9, Issue 6, 2003, Pages 744-749

  Kabashima, Kenji ^a   Sakata, Daiji ^a   Nagamachi, Miyako ^a   Miyachi, Yoshiki ^a   Inaba, Kayo ^b   Narumiya, Shuh ^a  

^a KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; PROSTAGLANDIN EP4 RECEPTOR; PROSTAGLANDIN RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; EP4 RECEPTOR; ISOPROTEIN; PROSTAGLANDIN E RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CELL MIGRATION; CONTACT ALLERGY; CONTACT SENSITIZATION; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; LANGHANS GIANT CELL; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SKIN; T LYMPHOCYTE; WILD TYPE; ANIMAL; C57BL MOUSE; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; DRUG POTENTIATION; EAR; GENE; GENETICS; HISTOLOGY; IMMUNOLOGY; LANGERHANS CELL; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

ANIMALIA;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; DINOPROSTONE; EAR; FEMALE; GENES, MHC CLASS II; LANGERHANS CELLS; LYMPH NODES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN ISOFORMS; RECEPTORS, PROSTAGLANDIN E; SIGNAL TRANSDUCTION; SKIN;

EID: 0038240422     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm872     Document Type: Article

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