A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins

Journal of Cell Biology

Volumn 139, Issue 6, 1997, Pages 1567-1581

  Felding Habermann, Brunhilde ^a   Silletti, Steve ^a   Mei, Fang ^a   Siu, Chi Hung ^b   Yip, Paul M ^b   Brooks, Peter C ^a   Cheresh, David A ^a   O'Toole, Timothy E ^a   Ginsberg, Mark H ^a   Montgomery, Anthony M P ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; IMMUNOGLOBULIN; INTEGRIN; MAGNESIUM ION; MANGANESE; NERVE CELL ADHESION MOLECULE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THROMBOCYTE; THROMBOGENESIS; UMBILICAL VEIN; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ADULT; AMINO ACID SEQUENCE; ANIMALS; BLOOD PLATELETS; CELL ADHESION; CHO CELLS; CRICETINAE; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOGLOBULINS; KINETICS; LEUKOCYTE L1 ANTIGEN COMPLEX; MEMBRANE FUSION; MOLECULAR SEQUENCE DATA; NEURAL CELL ADHESION MOLECULES; OLIGOPEPTIDES; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 15644366702     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.6.1567     Document Type: Article

References (63)

1. Bateman, A., M. Jouet, J. Macfarlane, J.-S. Du, S. Kenwrick, and C. Chothia. 1996. Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disorders. EMBO (Eur. Mol. Biol. Organ.) J. 15:6050-6059.
2. Bock, E.C., C. Richter-Landsberg, A. Faissner, and M. Schachner. 1985. Demonstration of immunochemical identity between the nerve growth factor-inducible large external (NILE) glycoprotein and the cell adhesion molecule L1. EMBO (Eur. Mol. Biol. Organ.) J. 4:2765-2768.
3. Brooks, P.C., R.A. Clark, and D.A. Cheresh. 1994. Requirement of vascular integrin α-v β-3 for angiogenesis. Science. 264:569-571.
4. Brown, P.J., and R.L. Juliano. 1985. Selective inhibition of fibronectin-mediated adhesion by monoclonal antibodies to a cell surface glycoprotein. Science. 228:1448-1451.
5. Cheresh, D.A., and R.C. Spiro. 1987. Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen and von Willebrand factor. J. Biol. Chem. 262:17703-17711.
6. Coller B.S., J.D. Folts, L.E. Scudder, and S.R. Smith. 1986. Antithrombotic effect of a monoclonal antibody to the platelet glycoprotein IIb/IIIa receptor in an animal experimental model. Blood. 68:783-786.
7. 5 integrins in avian neural crest cell adhesion and migration on vitronectin. Development (Camb.). 120:2687-2702.
8. Diaz-Gonzalez, F., J. Forsyth, B. Steiner, and M.H. Ginsberg. 1996. Trans-dominant inhibition of integrin function. Mol. Biol. Cell. 7:1939-1951.
9. Drescher, B., E. Spiess, M. Schachner, and R. Probstmeier. 1996. Structural analysis of the murine cell adhesion molecule L1 by electron microscopy and computer-assisted modelling. Eur. J. Neurosci. 8:2467-2478.
10. D'Souza, S.E., M.H. Ginsberg, and E.F. Plow. 1991. Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif. Trends Biochem. Sci. 16:246-250.
11. D'Souza, S.E., T.A. Haas, R.S. Piotrowicz, V. Byers-Ward, D.E. McGrath, H.R. Soule, C. Cierniewski, E.F. Plow, and J.W. Smith. 1994. Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: cation displacement is involved in ligand binding. Cell. 79:659-667.
12. 3-mediated migration of human tumor cells and activated T lymphocytes. Biochem. Biophys. Res. Commun. 232:236-239.
13. 3 integrin. Eur. J. Immunol. 26:2508-2516.
14. Feizi, T. 1994. Evidence for carbohydrate-mediated interactions between the neural-cell-adhesion molecules NCAM and L1. Trends Biochem. Sci. 19: 233-234.
15. 3 integrins in melanoma cell adhesion to activated platelets under flow. J. Biol. Chem. 271:5892-5900.
16. Felsenfeld, D.P., M.A. Hynes, K.M. Skoler, A.J. Furley, and T.M. Jessell. 1994. TAG-1 can mediate homophilic binding, but neurite outgrowth on TAG-1 requires an L1-like molecule and β1 integrins. Neuron. 12:675-690.
17. Friedlander, D.R., P. Milev, L. Karthikeyan, R.K. Margolis, R.U. Margolis, and M. Grumet. 1994. The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth. J. Cell Biol. 125: 669-680.
18. 3 integrin) confers fibrinogen- and activation-dependent aggregation on heterologous cells. Blood. 78:369-376.
19. Grumet, M., S. Hoffman, C.M. Chuong, and G.M. Edelman. 1984. Polypeptide components and binding functions of neuron-glia cell adhesion molecules. Proc. Natl. Acad. Sci. USA. 81:7989-7993.
20. Grumet, M., A. Flaccus, and R.U. Margolis. 1993. Functional characterization of chondroitin sulfate proteoglycans of brain: Interactions with neurons and neural cell adhesion molecules. J. Cell. Biol. 120:815-824.
21. Haas, T., and E.F. Plow. 1994. Integrin-ligand interactions: a year in review. Curr. Opin. Cell Biol. 6:656-662.
22. Hall, H., S. Carbonetto, and M. Schachner. 1997. L1/HNK-1 carbohydrate- and β1 integrin-dependent neural cell adhesion to laminin. J. Neurochem. 68: 544-553.
23. 3 selected from random phage display libraries. Biochemistry. 34:3948-3955.
24. Higuchi, R. 1990. Recombinant PCR in PCR Protocols: A Guide to Methods and Applications. M.A. Innis, D.H. Gelfand, J.J. Sninsky, and T.J. White, editors. Academic Press, San Diego. 177-183.
25. Hughes, S.E. 1996. Functional characterization of the spontaneously transformed human umbilical vein endothelial cell line ECV304: use in an in vitro model of angiogenesis. Exp. Cell Res. 225:171-185.
26. Jouet, M., A. Rosenthal, and S. Kenwrick. 1995. Exon 2 of the gene for neural cell adhesion molecule L1 is alternatively spliced in B cells. Brain Res. Mol. Brain Res. 30:378-380.
27. Kadmon, G., F. von Bohlen und Halbach, R. Horstkorte, M. Eckert, P. Altevogt, and M. Schachner. 1995. Evidence for a cis interaction and cooperative signalling by the heat-stable antigen nectadrin (murine CD24) and the cell adhesion molecule L1 in neurons. Eur. J. Neurosci. 7:993-1004.
28. Kirchhofer, D., J. Grzesiaki, and M.D. Pierschbacher. 1991. Calcium as a potential physiological regulator of integrin-mediated cell adhesion. J. Biol. Chem. 266:4471-4477.
29. 1 integrin from phage display library. J. Biol. Chem. 268:20205-20220.
30. Koivunenm E., B. Wang, C.D. Dickinson, and E. Ruoslahti. 1994. Peptides in cell adhesion research. Methods Enzymol. 245:346-369.
31. Kowitz, A., G. Kadmon, M. Eckert, V. Schirrmacher, M. Schachner, and P. Altevogt. 1992. Expression and function of the neural cell adhesion molecule L1 in mouse leukocytes. Eur. J. Immunol. 22:1199-1205.
32. Kuhn, T.B., E.T. Stoeckli, M.A. Condrau, F.G. Rathjen, and P. Sonderegger. 1991. Neurite outgrowth on immobilized Axonin-1 is mediated by a heterophilic interaction with L1(G4). J. Cell. Biol. 115:1113-1126.
33. 3 integrins. J. Biol. Chem. 272: 4103-4107.
34. Kujat, R., F. Miragall, D. Krause, R. Dermietzel, and K.H. Wrobel. 1995. Immunolocalization of the neural cell adhesion molecule L1 in non-proliferating epithelial cells of the male urogenital tract. Histochem. Cell Biol. 103: 311-321.
35. Lagenaur, C., and V. Lemmon. 1987. An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc. Natl. Acad. Sci. USA. 84:7753-7757.
36. Lemmon, V., and S. McLoon. 1986. The appearence of an L1-like molecule in the chick visual pathway. J. Neurosci. 6:2987-2994.
37. Lemmon, V., K.L. Farr, and C. Lagenaur. 1989. L1-mediated axon outgrowth occurs via a homophilic binding mechanism. Neuron. 2:1597-1603.
38. Lindner, J., F.G. Rathjen, and M. Schachner. 1983. L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum. Nature. 305:427-430.
39. Linnemann, D., A. Raz, and E. Bock. 1989. Differential expression of cell adhesion molecules in variants of the K1735 melanoma cells differing in metastatic capacity. Int. J. Cancer. 43:709-712.
40. 1 to mediate spreading on fibronectin. J. Cell Sci. 108:1227-1238.
41. Martini, R., and M. Schachner. 1986. Immunoelectron microscopic localization of neural cell adhesion molecules (L-1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J. Cell Biol. 103:2439-2448.
42. 1 integrin expressed on oligodendrocyte precursors. J. Neurosci. 16:7240-7252.
43. Mitjans, F., D. Sanders, J. Adan, A. Sutter, J.M. Martinez, C.-S. Jaggle, J.M. Moyano, H.-G. Kreysch, J. Piulats, and S.L. Goodman. 1995. An anti-αv-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice. J. Cell Science. 108:2825-2838.
44. Montgomery, A.M.P., J.C. Becker, C.-H. Siu, V. Lemmon, D.A. Cheresh, J.D. Pancook, X. Zhoa, and R.A. Reisfeld. 1996. Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin αvβ3. J. Cell Biol. 132:475-485.
45. Moos, M., R. Tacke, H. Scherer, D. Peplow, K. Früh, and M. Schachner. 1988. Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature. 334:701-703.
46. Mujoo, K., R.C. Spiro, and R.A. Reisfeld. 1986. Characterization of a unique glycoprotein antigen expressed on the surface of human neuroblastoma cells. J. Biol. Chem. 261:10299-10309.
47. 1-fibronectin interactions by divalent cations. J. Biol. Chem. 270:26270-26277.
48. Niija, K., E. Hodson, R. Bader, V. Byers-Ward, J.A. Koziol, E.F. Plow, and Z.M. Ruggeri. 1987. Increased surface expression of the membrane glycoprotein IIbIIIa complex induced by platelet activation: relationship to the binding of fibrinogen and platelet aggregation. Blood. 70:475-483.
49. Olive, S., C. Dubois, M. Schachner, and G. Rougon. 1995. The F3 neuronal glycosylphosphatidyl inositol-linked molecule is localized to glycolipid-enriched membrane subdomains and interacts with L1 and fyn kinase in cerebellum. J. Neurochem. 65:2307-2317.
50. O'Neil, K.T., R.H. Hoess, S.A. Jackson, N.S. Ramachandran, S.A. Mousa, and W.F. DeGrado. 1992. Identification of novel peptide antagonists for GPIIb/IIIa from a conformationally constrained phage peptide library. Proteins. 14: 509-515.
51. O'Toole, T.E., J.C. Loftus, E.F. Plow, A.A. Glass, J.R. Harper, and M.H. Ginsberg. 1989. Efficient surface expression of platelet GPIIb-IIIa requires both subunits. Blood. 74:14-18.
52. 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul. 1:883-893.
53. O'Toole, T.E., Y. Katagiri, R.J. Faull, K. Peter, R. Tamura, V. Quaranta, J.C. Loftus, S.J. Shattil, and M.H. Ginsberg. 1994. Integrin cytoplasmic domains mediate inside-out signal transduction. J. Cell Biol. 124:1047-1059.
54. Pancook, J.D., R.A. Reisfeld, N. Varki, A. Vitiello, R.I. Fox, and A.M.P. Montgomery. 1997. Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin. J. Immunol. 158:4413-4421.
55. Poltorak, M., K. Shimoda, and W.J. Freed. 1990. Cell adhesion molecules (CAMs) in adrenal medulla in situ and in vitro: Enhancement of chromaffin cell L1/Ng-CAM expression by NGF. Exp. Neurol. 110:52-72.
56. Rathjen, F.G., and M. Schachner. 1984. Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion. EMBO (Eur. Mol. Biol. Organ.) J.3:1-10.
57. Reid, R.A., and J.J. Hemperly. 1992. Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA. J. Mol. Neurosci. 3:127-135.
58. Ruppert, M., S. Aigner, M. Hubbe, H. Yagita, and P. Altevogt. 1995. The L1 adhesion molecule is a cellular ligand for VLA-5. J. Cell Biol. 131:1881-1891.
59. 1 integrin and the neural adhesion molecule L1. J. Neurosci. Res. 43:12-31.
60. Sonderegger, P.R., and F.G. Rathjen. 1992. Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily. J. Cell Biol. 119:1387-1394.
61. Suehiro, K., J.W. Smith, and E.F. Plow. 1996. The ligand recognition specificity of β3 integrins. J. Biol. Chem. 271:10365-10371.
62. Thor, G., R. Probstmeier, and M. Schachner. 1987. Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine. EMBO (Eur. Mol. Biol. Organ.) J. 6:2.581-2586.
63. Zhao, X., and C-H. Siu. 1995. Co-localization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to the second Ig-like domain. J. Biol. Chem. 270:29413-29421.