Phospholipase D2 mediates survival signaling through direct regulation of akt in glioblastoma cells

Journal of Biological Chemistry

Volumn 289, Issue 2, 2014, Pages 600-616

  Bruntz, Ronald C ^a   Taylor, Harry E ^b   Lindsley, Craig W ^a,c,d   Brown, H Alex ^a,c,e  

^a VANDERBILT UNIVERSITY   (United States)

^b Scott and White   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^e VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CELLULAR PROCESS; GLIOBLASTOMA CELLS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D;

CELL DEATH; CELL PROLIFERATION;

CELL SIGNALING;

BECLIN 1; PHOSPHATIDIC ACID; PHOSPHOLIPASE D2; PHOSPHOLIPASE INHIBITOR; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VU 0359595; VU 0364739; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; ENZYME INHIBITOR; FUSED HETEROCYCLIC RINGS; MEMBRANE PROTEIN; PHOSPHOLIPASE D; RUNDATAXIN PROTEIN, HUMAN; SIGNAL PEPTIDE;

ARTICLE; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; GLIOBLASTOMA; GLIOBLASTOMA CELL; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; AKT; ANIMAL; CELL LINE; CELL SIGNALING; CELL STRAIN HEK293; CONFOCAL MICROSCOPY; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AKT; AUTOPHAGY; CELL SIGNALING; GLIOBLASTOMA; PHOSPHATIDIC ACID; PHOSPHOLIPASE D;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; GLIOBLASTOMA; HEK293 CELLS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 84891947916     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.532978     Document Type: Article

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