Binding of the PX domain of p47phox to phosphatidylinositol 3, 4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

EMBO Journal

Volumn 21, Issue 19, 2002, Pages 5057-5068

  Karathanassis, Dimitrios ^a   Stahelin, Robert V ^a   Bravo, Jerónimo ^a   Perisic, Olga ^a   Pacold, Christine M ^a   Cho, Wonhwa ^a   Williams, Roger L ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

NADPH oxidase; p40; Phagocyte; Phosphatidic acid; Phosphoinositide; SH3 domains

Indexed keywords

GLUTAMIC ACID; INOSITOL DERIVATIVE; PHOSPHATIDIC ACID; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PHOSPHATIDYLSERINE; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERINE; SULFATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; MEMBRANE BINDING; MOLECULAR INTERACTION; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; X RAY ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CELL MEMBRANE; CLONING, MOLECULAR; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NADPH OXIDASE; PHOSPHATIDIC ACIDS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHATIDYLINOSITOLS; PHOSPHOPROTEINS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036791737     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf519     Document Type: Article

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