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Biochimica et Biophysica Acta - General Subjects

Volumn 1526, Issue 3, 2001, Pages 257-268

Expression, purification, characterization and homology modeling of active Akt/PKB, a key enzyme involved in cell survival signaling

(7) Kumar, C C a Diao, R a Yin, Z a Liu, Y H a Samatar, A A a Madison, V a Xiao, L a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Activation; Akt1; Expression; Kinetics; Recombinant

Indexed keywords

AKT ENZYME; AMINO ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; INHIBITOR PROTEIN; ISOENZYME; OKADAIC ACID; PEPTIDE; PROTEIN KINASE C INHIBITOR; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACULOVIRUS; BIOTINYLATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; INSECT; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE; VIRUS RECOMBINANT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; BACULOVIRIDAE; CELL LINE; CELL SURVIVAL; CLONING, MOLECULAR; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; HUMANS; ISOENZYMES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; OKADAIC ACID; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0035877156 PISSN: 03044165 EISSN: None Source Type: Journal
DOI: 10.1016/S0304-4165(01)00143-X Document Type: Article

Times cited : (33)

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