Mutation of Y179 on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K-and Akt-dependent manner

Cellular Signalling

Volumn 20, Issue 1, 2008, Pages 176-185

  Fulvio, Mauricio Di ^a   Frondorf, Kathleen ^a   Gomez Cambronero, Julian ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

AKT; DNA synthesis; Phosphorylation; PI3K; PLD2

Indexed keywords

CYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE D2; PROTEIN KINASE B; PROTEIN P42; PROTEIN P44; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHOLIPASE D; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE PROGRESSION; CELL STRAIN COS7; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; ANIMAL; CELL LINE; CELL PROLIFERATION; CELL STRAIN COS1; CERCOPITHECUS; CYTOLOGY; GENETIC TRANSFECTION; GENETICS; KIDNEY; MACROPHAGE; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA; KIDNEY; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; MUTATION; PHOSPHOLIPASE D; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION;

EID: 36249032598     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.10.009     Document Type: Article

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