-
1
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
G. Bergers, D. Hanahan, Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8, 592-603 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
2
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
J. M. Ebos, C. R. Lee, W. Cruz-Munoz, G. A. Bjarnason, J. G. Christensen, R. S. Kerbel, Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
3
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
M. Pàez-Ribes, E. Allen, J. Hudock, T. Takeda, H. Okuyama, F. Viñals, M. Inoue, G. Bergers, D. Hanahan, O. Casanovas, Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Pàez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Viñals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
4
-
-
23644455714
-
Phospholipase D: A lipid centric review
-
G. M. Jenkins, M. A. Frohman, Phospholipase D: A lipid centric review. Cell. Mol. Life Sci. 62, 2305-2316 (2005).
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 2305-2316
-
-
Jenkins, G.M.1
Frohman, M.A.2
-
5
-
-
38449089669
-
Expression of phospholipase D2 in human colorectal carcinoma
-
M. Saito, M. Iwadate, M. Higashimoto, K. Ono, Y. Takebayashi, S. Takenoshita, Expression of phospholipase D2 in human colorectal carcinoma. Oncol. Rep. 18, 1329-1334 (2007).
-
(2007)
Oncol. Rep.
, vol.18
, pp. 1329-1334
-
-
Saito, M.1
Iwadate, M.2
Higashimoto, M.3
Ono, K.4
Takebayashi, Y.5
Takenoshita, S.6
-
6
-
-
0032945387
-
Phospholipase Dactivity in human gastric carcinoma
-
N. Uchida, S.Okamura, H. Kuwano, Phospholipase Dactivity in human gastric carcinoma. Anticancer Res. 19, 671-675 (1999).
-
(1999)
Anticancer Res.
, vol.19
, pp. 671-675
-
-
Uchida, N.1
Okamura, S.2
Kuwano, H.3
-
7
-
-
0034695165
-
Overexpression of phospholipase D1 in human breast cancer tissues
-
D. Y. Noh, S. J. Ahn, R. A. Lee, I. A. Park, J. H. Kim, P. G. Suh, S. H. Ryu, K. H. Lee, J. S. Han, Overexpression of phospholipase D1 in human breast cancer tissues. Cancer Lett. 161, 207-214 (2000).
-
(2000)
Cancer Lett.
, vol.161
, pp. 207-214
-
-
Noh, D.Y.1
Ahn, S.J.2
Lee, R.A.3
Park, I.A.4
Kim, J.H.5
Suh, P.G.6
Ryu, S.H.7
Lee, K.H.8
Han, J.S.9
-
8
-
-
0030906933
-
Increased phospholipase D activity in human breast cancer
-
N. Uchida, S. Okamura, Y. Nagamachi, S. Yamashita, Increased phospholipase D activity in human breast cancer. J. Cancer Res. Clin. Oncol. 123, 280-285 (1997).
-
(1997)
J. Cancer Res. Clin. Oncol.
, vol.123
, pp. 280-285
-
-
Uchida, N.1
Okamura, S.2
Nagamachi, Y.3
Yamashita, S.4
-
9
-
-
0034638599
-
Increased activity and intranuclear expression of phospholipase D2 in human renal cancer
-
Y. Zhao, H. Ehara, Y. Akao, M. Shamoto, Y. Nakagawa, Y. Banno, T. Deguchi, N. Ohishi, K. Yagi, Y. Nozawa, Increased activity and intranuclear expression of phospholipase D2 in human renal cancer. Biochem. Biophys. Res. Commun. 278, 140-143 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 140-143
-
-
Zhao, Y.1
Ehara, H.2
Akao, Y.3
Shamoto, M.4
Nakagawa, Y.5
Banno, Y.6
Deguchi, T.7
Ohishi, N.8
Yagi, K.9
Nozawa, Y.10
-
10
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
L. D.Wood, D.W. Parsons, S. Jones, J. Lin, T. Sjöblom, R. J. Leary, D. Shen, S. M. Boca, T. Barber, J. Ptak, N. Silliman, S. Szabo, Z. Dezso, V. Ustyanksky, T. Nikolskaya, Y. Nikolsky, R. Karchin, P. A. Wilson, J. S. Kaminker, Z. Zhang, R. Croshaw, J. Willis, D. Dawson, M. Shipitsin, J. K. Willson, S. Sukumar, K. Polyak, B. H. Park, C. L. Pethiyagoda, P. V. Pant, D. G. Ballinger, A. B. Sparks, J. Hartigan, D. R. Smith, E. Suh, N. Papadopoulos, P. Buckhaults, S. D. Markowitz, G. Parmigiani, K.W. Kinzler, V. E. Velculescu, B. Vogelstein, The genomic landscapes of human breast and colorectal cancers. Science 318, 1108-1113 (2007).
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjöblom, T.5
Leary, R.J.6
Shen, D.7
Boca, S.M.8
Barber, T.9
Ptak, J.10
Silliman, N.11
Szabo, S.12
Dezso, Z.13
Ustyanksky, V.14
Nikolskaya, T.15
Nikolsky, Y.16
Karchin, R.17
Wilson, P.A.18
Kaminker, J.S.19
Zhang, Z.20
Croshaw, R.21
Willis, J.22
Dawson, D.23
Shipitsin, M.24
Willson, J.K.25
Sukumar, S.26
Polyak, K.27
Park, B.H.28
Pethiyagoda, C.L.29
Pant, P.V.30
Ballinger, D.G.31
Sparks, A.B.32
Hartigan, J.33
Smith, D.R.34
Suh, E.35
Papadopoulos, N.36
Buckhaults, P.37
Markowitz, S.D.38
Parmigiani, G.39
Kinzler, K.W.40
Velculescu, V.E.41
Vogelstein, B.42
more..
-
11
-
-
0037294303
-
Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer
-
Y. Yamada, N. Hamajima, T. Kato, H. Iwata, Y. Yamamura, M. Shinoda, M. Suyama, T. Mitsudomi, K. Tajima, S. Kusakabe, H. Yoshida, Y. Banno, Y. Akao, M. Tanaka, Y. Nozawa, Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer. J. Mol. Med. 81, 126-131 (2003).
-
(2003)
J. Mol. Med.
, vol.81
, pp. 126-131
-
-
Yamada, Y.1
Hamajima, N.2
Kato, T.3
Iwata, H.4
Yamamura, Y.5
Shinoda, M.6
Suyama, M.7
Mitsudomi, T.8
Tajima, K.9
Kusakabe, S.10
Yoshida, H.11
Banno, Y.12
Akao, Y.13
Tanaka, M.14
Nozawa, Y.15
-
12
-
-
34447568476
-
Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos
-
C. Zhao, G. Du, K. Skowronek, M. A. Frohman, D. Bar-Sagi, Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat. Cell Biol. 9, 706-712 (2007).
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 706-712
-
-
Zhao, C.1
Du, G.2
Skowronek, K.3
Frohman, M.A.4
Bar-Sagi, D.5
-
13
-
-
33745007067
-
The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis
-
C. S. Lee, I. S. Kim, J. B. Park, M. N. Lee, H. Y. Lee, P. G. Suh, S. H. Ryu, The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis. Nat. Cell Biol. 8, 477-484 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 477-484
-
-
Lee, C.S.1
Kim, I.S.2
Park, J.B.3
Lee, M.N.4
Lee, H.Y.5
Suh, P.G.6
Ryu, S.H.7
-
14
-
-
0033534687
-
Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent Raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway
-
M. A. Rizzo, K. Shome, C. Vasudevan, D. B. Stolz, T. C. Sung, M. A. Frohman, S. C. Watkins, G. Romero, Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent Raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. J. Biol. Chem. 274, 1131-1139 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1131-1139
-
-
Rizzo, M.A.1
Shome, K.2
Vasudevan, C.3
Stolz, D.B.4
Sung, T.C.5
Frohman, M.A.6
Watkins, S.C.7
Romero, G.8
-
15
-
-
33751309077
-
Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D
-
L. Hui, Y. Zheng, Y. Yan, J. Bargonetti, D. A. Foster, Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D. Oncogene 25, 7305-7310 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 7305-7310
-
-
Hui, L.1
Zheng, Y.2
Yan, Y.3
Bargonetti, J.4
Foster, D.A.5
-
16
-
-
23844465938
-
Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc
-
V. Rodrik, Y. Zheng, F. Harrow, Y. Chen, D. A. Foster, Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc. Mol. Cell. Biol. 25, 7917-7925 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7917-7925
-
-
Rodrik, V.1
Zheng, Y.2
Harrow, F.3
Chen, Y.4
Foster, D.A.5
-
17
-
-
0038339003
-
Phospholipase D confers rapamycin resistance in human breast cancer cells
-
Y. Chen, Y. Zheng, D. A. Foster, Phospholipase D confers rapamycin resistance in human breast cancer cells. Oncogene 22, 3937-3942 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 3937-3942
-
-
Chen, Y.1
Zheng, Y.2
Foster, D.A.3
-
18
-
-
0033534682
-
Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells
-
B. T. Williger, W. T. Ho, J. H. Exton, Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells. J. Biol. Chem. 274, 735-738 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 735-738
-
-
Williger, B.T.1
Ho, W.T.2
Exton, J.H.3
-
19
-
-
33744943819
-
Phospholipase D couples survival and migration signals in stress response of human cancer cells
-
Y. Zheng, V. Rodrik, A. Toschi, M. Shi, L. Hui, Y. Shen, D. A. Foster, Phospholipase D couples survival and migration signals in stress response of human cancer cells. J. Biol. Chem. 281, 15862-15868 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15862-15868
-
-
Zheng, Y.1
Rodrik, V.2
Toschi, A.3
Shi, M.4
Hui, L.5
Shen, Y.6
Foster, D.A.7
-
20
-
-
60149085205
-
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-κB/Sp1-mediated signaling pathways
-
M. H. Park, B. H. Ahn, Y. K. Hong, D. S. Min, Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-κB/Sp1-mediated signaling pathways. Carcinogenesis 30, 356-365 (2009).
-
(2009)
Carcinogenesis
, vol.30
, pp. 356-365
-
-
Park, M.H.1
Ahn, B.H.2
Hong, Y.K.3
Min, D.S.4
-
21
-
-
78650591499
-
Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells
-
D. W. Kang, M. H. Park, Y. J. Lee, H. S. Kim, C. W. Lindsley, H. A. Brown, D. S. Min, Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells. Int. J. Cancer 128, 805-816 (2011).
-
(2011)
Int. J. Cancer
, vol.128
, pp. 805-816
-
-
Kang, D.W.1
Park, M.H.2
Lee, Y.J.3
Kim, H.S.4
Lindsley, C.W.5
Brown, H.A.6
Min, D.S.7
-
22
-
-
74949141215
-
Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis
-
W. Su, Q. Chen, M. A. Frohman, Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis. Future Oncol. 5, 1477-1486 (2009).
-
(2009)
Future Oncol.
, vol.5
, pp. 1477-1486
-
-
Su, W.1
Chen, Q.2
Frohman, M.A.3
-
23
-
-
77649315183
-
3 integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1
-
3 integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1. Sci. Signal. 3, ra1 (2010).
-
(2010)
Sci. Signal.
, vol.3
-
-
Elvers, M.1
Stegner, D.2
Hagedorn, I.3
Kleinschnitz, C.4
Braun, A.5
Kuijpers, M.E.6
Boesl, M.7
Chen, Q.8
Heemskerk, J.W.9
Stoll, G.10
Frohman, M.A.11
Nieswandt, B.12
-
24
-
-
84862166355
-
The phospholipase D1 pathway modulates macroautophagy
-
C. Dall'Armi, A. Hurtado-Lorenzo, H. Tian, E. Morel, A. Nezu, R. B. Chan, W. H. Yu, K. S. Robinson, O. Yeku, S. A. Small, K. Duff, M. A. Frohman, M. R.Wenk, A. Yamamoto, G. Di Paolo, The phospholipase D1 pathway modulates macroautophagy. Nat. Commun. 1, 142 (2010).
-
(2010)
Nat. Commun.
, vol.1
, pp. 142
-
-
Dall'Armi, C.1
Hurtado-Lorenzo, A.2
Tian, H.3
Morel, E.4
Nezu, A.5
Chan, R.B.6
Yu, W.H.7
Robinson, K.S.8
Yeku, O.9
Small, S.A.10
Duff, K.11
Frohman, M.A.12
Wenk, M.R.13
Yamamoto, A.14
Di Paolo, G.15
-
25
-
-
78650064098
-
Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits
-
T. G. Oliveira, R. B. Chan, H. Tian, M. Laredo, G. Shui, A. Staniszewski, H. Zhang, L. Wang, T. W. Kim, K. E. Duff, M. R. Wenk, O. Arancio, G. Di Paolo, Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J. Neurosci. 30, 16419-16428 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 16419-16428
-
-
Oliveira, T.G.1
Chan, R.B.2
Tian, H.3
Laredo, M.4
Shui, G.5
Staniszewski, A.6
Zhang, H.7
Wang, L.8
Kim, T.W.9
Duff, K.E.10
Wenk, M.R.11
Arancio, O.12
Di Paolo, G.13
-
26
-
-
58249115241
-
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
-
S. A. Scott, P. E. Selvy, J. R. Buck, H. P. Cho, T. L. Criswell, A. L. Thomas, M. D. Armstrong, C. L. Arteaga, C. W. Lindsley, H. A. Brown, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat. Chem. Biol. 5, 108-117 (2009).
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 108-117
-
-
Scott, S.A.1
Selvy, P.E.2
Buck, J.R.3
Cho, H.P.4
Criswell, T.L.5
Thomas, A.L.6
Armstrong, M.D.7
Arteaga, C.L.8
Lindsley, C.W.9
Brown, H.A.10
-
27
-
-
62149152761
-
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis
-
W. Su, O. Yeku, S. Olepu, A. Genna, J. S. Park, H. Ren, G. Du, M. H. Gelb, A. J. Morris, M. A. Frohman, 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol. Pharmacol. 75, 437-446 (2009).
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 437-446
-
-
Su, W.1
Yeku, O.2
Olepu, S.3
Genna, A.4
Park, J.S.5
Ren, H.6
Du, G.7
Gelb, M.H.8
Morris, A.J.9
Frohman, M.A.10
-
28
-
-
78649704325
-
Autophagy and metabolism
-
J. D. Rabinowitz, E. White, Autophagy and metabolism. Science 330, 1344-1348 (2010).
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
29
-
-
1242296871
-
Rho activity critically and selectively regulates endothelial cell organization during angiogenesis
-
M. V. Hoang, M. C. Whelan, D. R. Senger, Rho activity critically and selectively regulates endothelial cell organization during angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 101, 1874-1879 (2004).
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 1874-1879
-
-
Hoang, M.V.1
Whelan, M.C.2
Senger, D.R.3
-
30
-
-
0035355472
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells
-
T. Takahashi, S. Yamaguchi, K. Chida, M. Shibuya, A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells. EMBO J. 20, 2768-2778 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
31
-
-
0842308307
-
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
-
L. Lamalice, F. Houle, G. Jourdan, J. Huot, Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38. Oncogene 23, 434-445 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 434-445
-
-
Lamalice, L.1
Houle, F.2
Jourdan, G.3
Huot, J.4
-
32
-
-
2542455474
-
The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
-
K. Holmqvist, M. J. Cross, C. Rolny, R. Hägerkvist, N. Rahimi, T. Matsumoto, L. Claesson-Welsh, M. Welsh, The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. J. Biol. Chem. 279, 22267-22275 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22267-22275
-
-
Holmqvist, K.1
Cross, M.J.2
Rolny, C.3
Hägerkvist, R.4
Rahimi, N.5
Matsumoto, T.6
Claesson-Welsh, L.7
Welsh, M.8
-
33
-
-
62849111751
-
Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: Competition with rapamycin
-
A. Toschi, E. Lee, L. Xu, A. Garcia, N. Gadir, D. A. Foster, Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: Competition with rapamycin. Mol. Cell. Biol. 29, 1411-1420 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1411-1420
-
-
Toschi, A.1
Lee, E.2
Xu, L.3
Garcia, A.4
Gadir, N.5
Foster, D.A.6
-
34
-
-
33947599083
-
Optimization of halopemide for phospholipase D2 inhibition
-
L. Monovich, B. Mugrage, E. Quadros, K. Toscano, R. Tommasi, S. LaVoie, E. Liu, Z. Du, D. LaSala, W. Boyar, P. Steed, Optimization of halopemide for phospholipase D2 inhibition. Bioorg. Med. Chem. Lett. 17, 2310-2311 (2007).
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 2310-2311
-
-
Monovich, L.1
Mugrage, B.2
Quadros, E.3
Toscano, K.4
Tommasi, R.5
LaVoie, S.6
Liu, E.7
Du, Z.8
LaSala, D.9
Boyar, W.10
Steed, P.11
-
35
-
-
0037332277
-
Arrest of B16 melanoma cells in the mouse pulmonary microcirculation induces endothelial nitric oxide synthase-dependent nitric oxide release that is cytotoxic to the tumor cells
-
H. Qiu, F. W. Orr, D. Jensen, H. H. Wang, A. R. McIntosh, B. B. Hasinoff, D. M. Nance, S. Pylypas, K. Qi, C. Song, R. J. Muschel, A. B. Al-Mehdi, Arrest of B16 melanoma cells in the mouse pulmonary microcirculation induces endothelial nitric oxide synthase-dependent nitric oxide release that is cytotoxic to the tumor cells. Am. J. Pathol. 162, 403-412 (2003).
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 403-412
-
-
Qiu, H.1
Orr, F.W.2
Jensen, D.3
Wang, H.H.4
McIntosh, A.R.5
Hasinoff, B.B.6
Nance, D.M.7
Pylypas, S.8
Qi, K.9
Song, C.10
Muschel, R.J.11
Al-Mehdi, A.B.12
-
36
-
-
0014865396
-
Metastasis: Quantitative analysis of distribution and fate of tumor emboli-labeled with 125 I-5-iodo-2′-deoxyuridine
-
I. J. Fidler, Metastasis: Quantitative analysis of distribution and fate of tumor emboli-labeled with 125 I-5-iodo-2′-deoxyuridine. J. Natl. Cancer Inst. 45, 773-782 (1970).
-
(1970)
J. Natl. Cancer Inst.
, vol.45
, pp. 773-782
-
-
Fidler, I.J.1
-
37
-
-
81255205399
-
Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
-
M. Labelle, S. Begum, R. O. Hynes, Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell 20, 576-590 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 576-590
-
-
Labelle, M.1
Begum, S.2
Hynes, R.O.3
-
38
-
-
0033559946
-
Lysis of tumor cells by natural killer cells in mice is impeded by platelets
-
B. Nieswandt, M. Hafner, B. Echtenacher, D. N. Männel, Lysis of tumor cells by natural killer cells in mice is impeded by platelets. Cancer Res. 59, 1295-1300 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 1295-1300
-
-
Nieswandt, B.1
Hafner, M.2
Echtenacher, B.3
Männel, D.N.4
-
39
-
-
3142592165
-
Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis
-
E. Camerer, A. A. Qazi, D. N. Duong, I. Cornelissen, R. Advincula, S. R. Coughlin, Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis. Blood 104, 397-401 (2004).
-
(2004)
Blood
, vol.104
, pp. 397-401
-
-
Camerer, E.1
Qazi, A.A.2
Duong, D.N.3
Cornelissen, I.4
Advincula, R.5
Coughlin, S.R.6
-
40
-
-
9244265563
-
Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation
-
J. H. Im, W. Fu, H. Wang, S. K. Bhatia, D. A. Hammer, M. A. Kowalska, R. J. Muschel, Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res. 64, 8613-8619 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 8613-8619
-
-
Im, J.H.1
Fu, W.2
Wang, H.3
Bhatia, S.K.4
Hammer, D.A.5
Kowalska, M.A.6
Muschel, R.J.7
-
41
-
-
0023946733
-
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo
-
S. Karpatkin, E. Pearlstein, C. Ambrogio, B. S. Coller, Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. J. Clin. Invest. 81, 1012-1019 (1988).
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1012-1019
-
-
Karpatkin, S.1
Pearlstein, E.2
Ambrogio, C.3
Coller, B.S.4
-
42
-
-
0036591801
-
Flow cytometric detection of activated mouse integrin αIIbß3 with a novel monoclonal antibody
-
W. Bergmeier, V. Schulte, G. Brockhoff, U. Bier, H. Zirngibl, B. Nieswandt, Flow cytometric detection of activated mouse integrin αIIbß3 with a novel monoclonal antibody. Cytometry 48, 80-86 (2002).
-
(2002)
Cytometry
, vol.48
, pp. 80-86
-
-
Bergmeier, W.1
Schulte, V.2
Brockhoff, G.3
Bier, U.4
Zirngibl, H.5
Nieswandt, B.6
-
43
-
-
63349108525
-
Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish
-
X. X. Zeng, X. Zheng, Y. Xiang, H. P. Cho, J. R. Jessen, T. P. Zhong, L. Solnica-Krezel, H. A. Brown, Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish. Dev. Biol. 328, 363-376 (2009).
-
(2009)
Dev. Biol.
, vol.328
, pp. 363-376
-
-
Zeng, X.X.1
Zheng, X.2
Xiang, Y.3
Cho, H.P.4
Jessen, J.R.5
Zhong, T.P.6
Solnica-Krezel, L.7
Brown, H.A.8
-
44
-
-
79959358969
-
Activation of cytosolic phospholipase A2 downstream of the Src-phospholipase D1 (PLD1)-protein kinase C γ (PKCγ) signaling axis is required for hypoxia-induced pathological retinal angiogenesis
-
Q. Zhang, D. Wang, N. K. Singh, V. Kundumani-Sridharan, L. Gadiparthi, C. M. Rao, G. N. Rao, Activation of cytosolic phospholipase A2 downstream of the Src-phospholipase D1 (PLD1)-protein kinase C γ (PKCγ) signaling axis is required for hypoxia-induced pathological retinal angiogenesis. J. Biol. Chem. 286, 22489-22498 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22489-22498
-
-
Zhang, Q.1
Wang, D.2
Singh, N.K.3
Kundumani-Sridharan, V.4
Gadiparthi, L.5
Rao, C.M.6
Rao, G.N.7
-
45
-
-
68949103681
-
Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells
-
D. A. Foster, Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells. Biochim. Biophys. Acta 1791, 949-955 (2009).
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 949-955
-
-
Foster, D.A.1
-
46
-
-
70949083239
-
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-β activity and TGF-β1 expression
-
F. Oriente, S. Iovino, A. Cassese, C. Romano, C. Miele, G. Troncone, M. Balletta, A. Perfetti, G. Santulli, G. Iaccarino, R. Valentino, F. Beguinot, P. Formisano, Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-β activity and TGF-β1 expression. Diabetologia 52, 2642-2652 (2009).
-
(2009)
Diabetologia
, vol.52
, pp. 2642-2652
-
-
Oriente, F.1
Iovino, S.2
Cassese, A.3
Romano, C.4
Miele, C.5
Troncone, G.6
Balletta, M.7
Perfetti, A.8
Santulli, G.9
Iaccarino, G.10
Valentino, R.11
Beguinot, F.12
Formisano, P.13
-
47
-
-
0016631547
-
Causes of death in cancer patients
-
J. L. Ambrus, C. M. Ambrus, I. B. Mink, J.W. Pickren, Causes of death in cancer patients. J. Med. 6, 61-64 (1975).
-
(1975)
J. Med.
, vol.6
, pp. 61-64
-
-
Ambrus, J.L.1
Ambrus, C.M.2
Mink, I.B.3
Pickren, J.W.4
-
48
-
-
33644597912
-
Incidence of venous thromboembolism and its effect on survival among patients with common cancers
-
H. K. Chew, T. Wun, D. Harvey, H. Zhou, R. H. White, Incidence of venous thromboembolism and its effect on survival among patients with common cancers. Arch. Intern. Med. 166, 458-464 (2006).
-
(2006)
Arch. Intern. Med.
, vol.166
, pp. 458-464
-
-
Chew, H.K.1
Wun, T.2
Harvey, D.3
Zhou, H.4
White, R.H.5
-
49
-
-
61449105940
-
Clinical studies with anticoagulants to improve survival in cancer patients
-
G. T. Gerotziafas, C. Papageorgiou, M. Hatmi, M. M. Samama, I. Elalamy, Clinical studies with anticoagulants to improve survival in cancer patients. Pathophysiol. Haemost. Thromb. 36, 204-211 (2008).
-
(2008)
Pathophysiol. Haemost. Thromb.
, vol.36
, pp. 204-211
-
-
Gerotziafas, G.T.1
Papageorgiou, C.2
Hatmi, M.3
Samama, M.M.4
Elalamy, I.5
-
50
-
-
61449093023
-
Blood coagulation and cancer: Thrombosis and survival, clinical relevance and impact. An introduction
-
J. H. Vestjens, S. Sassen, M. H. Prins, Blood coagulation and cancer: Thrombosis and survival, clinical relevance and impact. An introduction. Pathophysiol. Haemost. Thromb. 36, 113-121 (2008).
-
(2008)
Pathophysiol. Haemost. Thromb.
, vol.36
, pp. 113-121
-
-
Vestjens, J.H.1
Sassen, S.2
Prins, M.H.3
-
51
-
-
56649123212
-
Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis
-
S. R. Nalluri, D. Chu, R. Keresztes, X. Zhu, S. Wu, Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis. JAMA 300, 2277-2285 (2008).
-
(2008)
JAMA
, vol.300
, pp. 2277-2285
-
-
Nalluri, S.R.1
Chu, D.2
Keresztes, R.3
Zhu, X.4
Wu, S.5
-
53
-
-
0025364195
-
Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro
-
R. F. Nicosia, A. Ottinetti, Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab. Invest. 63, 115-122 (1990).
-
(1990)
Lab. Invest.
, vol.63
, pp. 115-122
-
-
Nicosia, R.F.1
Ottinetti, A.2
|