Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages

  Morrone, Seamus R ^a   Wang, Tao ^a   Constantoulakis, Leeza M ^a,b   Hooy, Richard M ^a   Delannoy, Michael J ^a   Sohn, Jungsan ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF NURSING   (United States)

Author keywords

Cooperative filament formation; Inflammasome

Indexed keywords

DOUBLE STRANDED DNA; INTERFERON INDUCIBLE PROTEIN 16; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HOST RESISTANCE; HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DNA BINDING; PROTEIN FUNCTION; QUANTITATIVE ASSAY;

COOPERATIVE FILAMENT FORMATION; INFLAMMASOME;

AMINO ACID SEQUENCE; BINDING, COMPETITIVE; CELL NUCLEUS; CROSS-LINKING REAGENTS; DNA; HUMANS; IMMUNITY, INNATE; INFLAMMATION; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 84891933102     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313577111     Document Type: Article

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