메뉴 건너뛰기




Volumn 54, Issue , 2014, Pages 559-580

Understanding and modulating mammalian-microbial communication for improved human health

Author keywords

Drug discovery; Irinotecan; Microbiome; NSAIDs; glucuronidase

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; BACTERIAL ENZYME; BETA GLUCURONIDASE; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROBIOTIC AGENT; XENOBIOTIC AGENT;

EID: 84891848483     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-011613-140007     Document Type: Review
Times cited : (38)

References (159)
  • 1
    • 0003342944 scopus 로고
    • Die darmbakterien des neugeborenen und sauglings
    • Escherich T. 1885. Die darmbakterien des neugeborenen und sauglings. Fortschr. Med. 3:447-547
    • (1885) Fortschr. Med. , vol.3 , pp. 447-547
    • Escherich, T.1
  • 2
    • 0007579207 scopus 로고
    • Is p-aminobenzenesulphonamide the active agent in prontosil therapy?
    • Fuller AT. 1937. Is p-aminobenzenesulphonamide the active agent in prontosil therapy? Lancet 229:194-98
    • (1937) Lancet , vol.229 , pp. 194-198
    • Fuller, A.T.1
  • 3
    • 0023907372 scopus 로고
    • Sulfasalazine: I. An historical perspective
    • Bachrach WH. 1988. Sulfasalazine: I. An historical perspective. Am. J. Gastroenterol. 83:487-96
    • (1988) Am. J. Gastroenterol , vol.83 , pp. 487-496
    • Bachrach, W.H.1
  • 4
    • 0023912898 scopus 로고
    • Sulfasalazine: II. Some notes on the discovery and development of salazopyrin
    • Svartz N. 1988. Sulfasalazine: II. Some notes on the discovery and development of salazopyrin. Am. J. Gastroenterol. 83:497-503
    • (1988) Am. J. Gastroenterol. , vol.83 , pp. 497-503
    • Svartz, N.1
  • 5
    • 0015757745 scopus 로고
    • Metabolism of foreign compounds by gastrointestinal microorganisms
    • Scheline RR. 1973. Metabolism of foreign compounds by gastrointestinal microorganisms. Pharmacol. Rev. 25:451-523
    • (1973) Pharmacol. Rev. , vol.25 , pp. 451-523
    • Scheline, R.R.1
  • 6
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy humanmicrobiome
    • Project HM. 2012. Structure, function and diversity of the healthy humanmicrobiome. Nature 486:207-14
    • (2012) Nature , vol.486 , pp. 207-214
    • Project, H.M.1
  • 7
    • 0035843993 scopus 로고    scopus 로고
    • Commensal host-bacterial relationships in the gut
    • Hooper LV, Gordon JI. 2001. Commensal host-bacterial relationships in the gut. Science 292:1115-18
    • (2001) Science , vol.292 , pp. 1115-1118
    • Hooper, L.V.1    Gordon, J.I.2
  • 8
    • 0035793372 scopus 로고    scopus 로고
    • Molecular analysis of commensal host-microbial relationships in the intestine
    • Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI. 2001. Molecular analysis of commensal host-microbial relationships in the intestine. Science 291:881-84
    • (2001) Science , vol.291 , pp. 881-884
    • Hooper, L.V.1    Wong, M.H.2    Thelin, A.3    Hansson, L.4    Falk, P.G.5    Gordon, J.I.6
  • 9
    • 60849116153 scopus 로고    scopus 로고
    • Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology
    • Tseng TT, Tyler BM, Setubal JC. 2009. Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology. BMC Microbiol. 9(Suppl. 1):S2
    • (2009) BMC Microbiol. , vol.9 , Issue.SUPPL. 1
    • Tseng, T.T.1    Tyler, B.M.2    Setubal, J.C.3
  • 10
    • 0020710588 scopus 로고
    • Dietary intake, energy metabolism, and excretory losses of adult male germfree Wistar rats
    • Wostmann BS, Larkin C, Moriarty A, Bruckner-Kardoss E. 1983. Dietary intake, energy metabolism, and excretory losses of adult male germfree Wistar rats. Lab. Anim. Sci. 33:46-50
    • (1983) Lab. Anim. Sci. , vol.33 , pp. 46-50
    • Wostmann, B.S.1    Larkin, C.2    Moriarty, A.3    Bruckner-Kardoss, E.4
  • 11
    • 0037180433 scopus 로고    scopus 로고
    • Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
    • Stappenbeck TS, Hooper LV, Gordon JI. 2002. Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc. Natl. Acad. Sci. USA 99:15451-55
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15451-15455
    • Stappenbeck, T.S.1    Hooper, L.V.2    Gordon, J.I.3
  • 12
    • 0019302074 scopus 로고
    • Lymphatic tissue of the intestinal tract of germfree and conventional rabbits
    • Štěpánková R, Kovář û F, Kruml J. 1980. Lymphatic tissue of the intestinal tract of germfree and conventional rabbits. Folia Microbiol. 25:491-95
    • (1980) Folia Microbiol. , vol.25 , pp. 491-495
    • Štěpánková, R.1    Kovář, Û.F.2    Kruml, J.3
  • 13
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
    • Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y. 1997. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol. 159:1739-45
    • (1997) J. Immunol. , vol.159 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.2    Tanaka, K.3    Aiba, Y.4    Kubo, C.5    Koga, Y.6
  • 14
    • 0033004028 scopus 로고    scopus 로고
    • Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system
    • Talham GL, Jiang HQ, Bos NA, Cebra JJ. 1999. Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system. Infect. Immun. 67:1992-2000
    • (1999) Infect. Immun. , vol.67 , pp. 1992-2000
    • Talham, G.L.1    Jiang, H.Q.2    Bos, N.A.3    Cebra, J.J.4
  • 15
    • 0034663923 scopus 로고    scopus 로고
    • Intestinal microflora and diversification of the rabbit antibody repertoire
    • Lanning D, Sethupathi P, Rhee KJ, Zhai SK, Knight KL. 2000. Intestinal microflora and diversification of the rabbit antibody repertoire. J. Immunol. 165:2012-19
    • (2000) J. Immunol. , vol.165 , pp. 2012-2019
    • Lanning, D.1    Sethupathi, P.2    Rhee, K.J.3    Zhai, S.K.4    Knight, K.L.5
  • 16
    • 1642495744 scopus 로고    scopus 로고
    • Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire
    • Rhee KJ, Sethupathi P, Driks A, Lanning DK, Knight KL. 2004. Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire. J. Immunol. 172:1118-24
    • (2004) J. Immunol. , vol.172 , pp. 1118-1124
    • Rhee, K.J.1    Sethupathi, P.2    Driks, A.3    Lanning, D.K.4    Knight, K.L.5
  • 17
    • 84874105332 scopus 로고    scopus 로고
    • Characterization of a S-layer protein from Lactobacillus crispatus K313 and the domains responsible for binding to cellwall and adherence to collagen
    • Sun Z, Kong J, Hu S, Kong W, Lu W, Liu W. 2013. Characterization of a S-layer protein from Lactobacillus crispatus K313 and the domains responsible for binding to cellwall and adherence to collagen. Appl. Microbiol. Biotechnol. 97:1941-52
    • (2013) Appl. Microbiol. Biotechnol. , vol.97 , pp. 1941-1952
    • Sun, Z.1    Kong, J.2    Hu, S.3    Kong, W.4    Lu, W.5    Liu, W.6
  • 18
    • 0038492443 scopus 로고    scopus 로고
    • Structural study of binding of flagellin by Toll-like receptor 5
    • Jacchieri SG, Torquato R, Brentani RR. 2003. Structural study of binding of flagellin by Toll-like receptor 5. J. Bacteriol. 185:4243-47
    • (2003) J. Bacteriol. , vol.185 , pp. 4243-4247
    • Jacchieri, S.G.1    Torquato, R.2    Brentani, R.R.3
  • 19
    • 58049202273 scopus 로고    scopus 로고
    • Inflammasomes: Guardians of cytosolic sanctity
    • Lamkanfi M, Dixit VM. 2009. Inflammasomes: guardians of cytosolic sanctity. Immunol. Rev. 227:95-105
    • (2009) Immunol. Rev. , vol.227 , pp. 95-105
    • Lamkanfi, M.1    Dixit, V.M.2
  • 20
    • 24644511609 scopus 로고    scopus 로고
    • Anchors away: Contribution of a glycolipid anchor to bacterial invasion of host cells
    • Baron MJ, Kasper DL. 2005. Anchors away: contribution of a glycolipid anchor to bacterial invasion of host cells. J. Clin. Investig. 115:2325-27
    • (2005) J. Clin. Investig. , vol.115 , pp. 2325-2327
    • Baron, M.J.1    Kasper, D.L.2
  • 21
    • 0033387055 scopus 로고    scopus 로고
    • Interaction of peptides and proteins with bacterial surface glycolipids: A comparison of glycosphingolipids and lipopolysaccharides
    • Wiese A, Seydel U. 1999. Interaction of peptides and proteins with bacterial surface glycolipids: a comparison of glycosphingolipids and lipopolysaccharides. J. Ind. Microbiol. Biotechnol. 23:414-24
    • (1999) J. Ind. Microbiol. Biotechnol. , vol.23 , pp. 414-424
    • Wiese, A.1    Seydel, U.2
  • 22
    • 84875326334 scopus 로고    scopus 로고
    • Host innate immune responses to microbial pathogens
    • Delaloye J, Calandra T. 2013. Host innate immune responses to microbial pathogens. Curr. Vasc. Pharmacol. 11:123-32
    • (2013) Curr. Vasc. Pharmacol. , vol.11 , pp. 123-132
    • Delaloye, J.1    Calandra, T.2
  • 23
    • 33745217596 scopus 로고    scopus 로고
    • A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases
    • Ivanov D, Emonet C, Foata F, Affolter M, Delley M, et al. 2006. A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases. J. Biol. Chem. 281:17246-52
    • (2006) J. Biol. Chem. , vol.281 , pp. 17246-17252
    • Ivanov, D.1    Emonet, C.2    Foata, F.3    Affolter, M.4    Delley, M.5
  • 24
    • 51349139676 scopus 로고    scopus 로고
    • Enhancement of gene expression by a peptide p(CHWPR) produced by Bifidobacterium lactis BB-12
    • Mitsuma T, Odajima H, Momiyama Z, Watanabe K, Masuguchi M, et al. 2008. Enhancement of gene expression by a peptide p(CHWPR) produced by Bifidobacterium lactis BB-12. Microbiol. Immunol. 52:144-55
    • (2008) Microbiol. Immunol. , vol.52 , pp. 144-155
    • Mitsuma, T.1    Odajima, H.2    Momiyama, Z.3    Watanabe, K.4    Masuguchi, M.5
  • 25
    • 78049494627 scopus 로고    scopus 로고
    • Extracellular proteins secreted by probiotic bacteria as mediators of effects that promote mucosa-bacteria interactions
    • Sanchez B, Urdaci MC, Margolles A. 2010. Extracellular proteins secreted by probiotic bacteria as mediators of effects that promote mucosa-bacteria interactions. Microbiology 156:3232-42
    • (2010) Microbiology , vol.156 , pp. 3232-3242
    • Sanchez, B.1    Urdaci, M.C.2    Margolles, A.3
  • 26
    • 84861833706 scopus 로고    scopus 로고
    • The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes
    • Rath CM, Dorrestein PC. 2012. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Curr. Opin. Microbiol. 15:147-54
    • (2012) Curr. Opin. Microbiol. , vol.15 , pp. 147-154
    • Rath, C.M.1    Dorrestein, P.C.2
  • 27
    • 61449176136 scopus 로고    scopus 로고
    • Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli
    • Henderson JP, Crowley JR, Pinkner JS, Walker JN, Tsukayama P, et al. 2009. Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog. 5:e1000305
    • (2009) PLoS Pathog. , vol.5
    • Henderson, J.P.1    Crowley, J.R.2    Pinkner, J.S.3    Walker, J.N.4    Tsukayama, P.5
  • 29
    • 79956075540 scopus 로고    scopus 로고
    • Colonization-induced host-gut microbial metabolic interaction
    • Claus SP, Ellero SL, Berger B, Krause L, Bruttin A, et al. 2011. Colonization-induced host-gut microbial metabolic interaction. mBio 2:e00271-10
    • (2011) MBio , vol.2
    • Claus, S.P.1    Ellero, S.L.2    Berger, B.3    Krause, L.4    Bruttin, A.5
  • 32
    • 38349127277 scopus 로고    scopus 로고
    • Inter-kingdom signalling: Communication between bacteria and their hosts
    • Hughes DT, Sperandio V. 2008. Inter-kingdom signalling: communication between bacteria and their hosts. Nat. Rev. Microbiol. 6:111-20
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 111-120
    • Hughes, D.T.1    Sperandio, V.2
  • 33
    • 78149295964 scopus 로고    scopus 로고
    • Alleviating cancer drug toxicity by inhibiting a bacterial enzyme
    • Wallace B, Wang H, Lane KT, Scoot JE, Orans J, et al. 2010. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science 330:831-35
    • (2010) Science , vol.330 , pp. 831-835
    • Wallace, B.1    Wang, H.2    Lane, K.T.3    Scoot, J.E.4    Orans, J.5
  • 34
    • 84872535919 scopus 로고    scopus 로고
    • Xenobiotics shape the physiology and gene expression of the active human gut microbiome
    • Maurice CF, Haiser HJ, Turnbaugh PJ. 2013. Xenobiotics shape the physiology and gene expression of the active human gut microbiome. Cell 152:39-50
    • (2013) Cell , vol.152 , pp. 39-50
    • Maurice, C.F.1    Haiser, H.J.2    Turnbaugh, P.J.3
  • 35
    • 62649151803 scopus 로고    scopus 로고
    • Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
    • Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, et al. 2009. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc. Natl. Acad. Sci. USA 106:3698-703
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3698-3703
    • Wikoff, W.R.1    Anfora, A.T.2    Liu, J.3    Schultz, P.G.4    Lesley, S.A.5
  • 36
    • 84871538443 scopus 로고    scopus 로고
    • Gut pharmacomicrobiomics: The tip of an iceberg of complex interactions between drugs and gut-associated microbes
    • Saad R, Rizkallah MR, Aziz RK. 2012. Gut pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes. Gut Pathog. 4:16
    • (2012) Gut Pathog. , vol.4 , pp. 16
    • Saad, R.1    Rizkallah, M.R.2    Aziz, R.K.3
  • 37
    • 17844404232 scopus 로고    scopus 로고
    • Gut microorganisms, mammalian metabolism and personalized health care
    • Nicholson JK, Holmes E, Wilson ID. 2005. Gut microorganisms, mammalian metabolism and personalized health care. Nat. Rev. Microbiol. 3:431-38
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 431-438
    • Nicholson, J.K.1    Holmes, E.2    Wilson, I.D.3
  • 38
    • 66649100229 scopus 로고    scopus 로고
    • Impact of gut microbiota on intestinal and hepatic levels of phase 2 xenobiotic-metabolizing enzymes in the rat
    • Meinl W, Sczesny S, Brigelius-Flohe R, Blaut M, Glatt H. 2009. Impact of gut microbiota on intestinal and hepatic levels of phase 2 xenobiotic- metabolizing enzymes in the rat. Drug Metab. Dispos. 37:1179-86
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 1179-1186
    • Meinl, W.1    Sczesny, S.2    Brigelius-Flohe, R.3    Blaut, M.4    Glatt, H.5
  • 39
    • 80054059835 scopus 로고    scopus 로고
    • Enteric microbiome metabolites correlate with response to simvastatin treatment
    • Kaddurah-Daouk R, Baillie RA, Zhu H, Zeng ZB, Wiest MM, et al. 2011. Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS ONE 6:e25482
    • (2011) PLoS ONE , vol.6
    • Kaddurah-Daouk, R.1    Baillie, R.A.2    Zhu, H.3    Zeng, Z.B.4    Wiest, M.M.5
  • 40
    • 84856374839 scopus 로고    scopus 로고
    • Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae
    • Stecher B, Denzler R, Maier L, Bernet F, Sanders MJ, et al. 2012. Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proc. Natl. Acad. Sci. USA 109:1269-74
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 1269-1274
    • Stecher, B.1    Denzler, R.2    Maier, L.3    Bernet, F.4    Sanders, M.J.5
  • 41
    • 0021922675 scopus 로고
    • Studies on the fate of the glutathione and cysteine conjugates of acetaminophen in mice
    • Fischer LJ, Green MD, Harman AW. 1985. Studies on the fate of the glutathione and cysteine conjugates of acetaminophen in mice. Drug Metab. Dispos. 13:121-26
    • (1985) Drug Metab. Dispos. , vol.13 , pp. 121-126
    • Fischer, L.J.1    Green, M.D.2    Harman, A.W.3
  • 42
    • 0028039193 scopus 로고
    • The metabolism of drugs by the gut flora
    • Mikov M. 1994. The metabolism of drugs by the gut flora. Eur. J. Drug Metab. Pharmacokinet. 19:201-7
    • (1994) Eur. J. Drug Metab. Pharmacokinet. , vol.19 , pp. 201-207
    • Mikov, M.1
  • 43
    • 34948823424 scopus 로고    scopus 로고
    • Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women
    • Bolca S, Possemiers S, Herregat A, Huybrechts I, Heyerick A, et al. 2007. Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women. J. Nutr. 137:2242-46
    • (2007) J. Nutr. , vol.137 , pp. 2242-2246
    • Bolca, S.1    Possemiers, S.2    Herregat, A.3    Huybrechts, I.4    Heyerick, A.5
  • 44
    • 35148830351 scopus 로고    scopus 로고
    • Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: A dietary intervention trial with fifty healthy post-menopausal Caucasian women
    • Bolca S, Possemiers S, Maervoet V, Huybrechts I, Heyerick A, et al. 2007. Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. Br. J. Nutr. 98:950-59
    • (2007) Br. J. Nutr. , vol.98 , pp. 950-959
    • Bolca, S.1    Possemiers, S.2    Maervoet, V.3    Huybrechts, I.4    Heyerick, A.5
  • 45
    • 0025667979 scopus 로고
    • The metabolism of anthranoid laxatives
    • de Witte P, Lemli L. 1990. The metabolism of anthranoid laxatives. Hepatogastroenterology 37:601-5
    • (1990) Hepatogastroenterology , vol.37 , pp. 601-605
    • De Witte, P.1    Lemli, L.2
  • 47
    • 0032470250 scopus 로고    scopus 로고
    • A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs
    • Okuda H, Ogura K, Kato A, Takubo H, Watabe T. 1998. A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs. J. Pharmacol. Exp. Ther. 287:791-99
    • (1998) J. Pharmacol. Exp. Ther. , vol.287 , pp. 791-799
    • Okuda, H.1    Ogura, K.2    Kato, A.3    Takubo, H.4    Watabe, T.5
  • 48
    • 0015581774 scopus 로고
    • Distribution studies of salicylazosulfapyridine and its metabolites
    • Peppercorn MA, Goldman P. 1973. Distribution studies of salicylazosulfapyridine and its metabolites. Gastroenterology 64:240-45
    • (1973) Gastroenterology , vol.64 , pp. 240-245
    • Peppercorn, M.A.1    Goldman, P.2
  • 50
    • 0014198434 scopus 로고
    • The bacterial degradation of chloramphenicol
    • Holt R. 1967. The bacterial degradation of chloramphenicol. Lancet 289:1259-60
    • (1967) Lancet , vol.289 , pp. 1259-1260
    • Holt, R.1
  • 51
    • 84867404198 scopus 로고    scopus 로고
    • Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
    • Bindels LB, Porporato P, Dewulf EM, Verrax J, Neyrinck AM, et al. 2012. Gut microbiota-derived propionate reduces cancer cell proliferation in the liver. Br. J. Cancer 107:1337-44
    • (2012) Br. J. Cancer , vol.107 , pp. 1337-1344
    • Bindels, L.B.1    Porporato, P.2    Dewulf, E.M.3    Verrax, J.4    Neyrinck, A.M.5
  • 52
    • 84872677660 scopus 로고    scopus 로고
    • The microbiota and its metabolites in colonic mucosal health and cancer risk
    • Vipperla K, O'Keefe SJ. 2012. The microbiota and its metabolites in colonic mucosal health and cancer risk. Nutr. Clin. Pract. 27:624-35
    • (2012) Nutr. Clin. Pract. , vol.27 , pp. 624-635
    • Vipperla, K.1    O'Keefe, S.J.2
  • 53
    • 84867199359 scopus 로고    scopus 로고
    • Gut microbiota: Colorectal cancer-driven by inflammation and gut bacteria?
    • Ray K. 2012. Gut microbiota: Colorectal cancer-driven by inflammation and gut bacteria? Nat. Rev. Gastroenterol. Hepatol. 9:558
    • (2012) Nat. Rev. Gastroenterol. Hepatol. , vol.9 , pp. 558
    • Ray, K.1
  • 55
    • 57849150175 scopus 로고    scopus 로고
    • Extracellular gelsolin binds lipoteichoic acid and modulates cellular response to proinflammatory bacterial wall components
    • Bucki R, Byfield FJ, Kulakowska A, McCormick ME, Drozdowski W, et al. 2008. Extracellular gelsolin binds lipoteichoic acid and modulates cellular response to proinflammatory bacterial wall components. J. Immunol. 181:4936-44
    • (2008) J. Immunol. , vol.181 , pp. 4936-4944
    • Bucki, R.1    Byfield, F.J.2    Kulakowska, A.3    McCormick, M.E.4    Drozdowski, W.5
  • 56
  • 57
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, et al. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:3749-52
    • (1999) J. Immunol. , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5
  • 58
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085-88
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3    Liu, M.Y.4    Van Huffel, C.5
  • 60
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round JL, Lee SM, Li J, Tran G, Jabri B, et al. 2011. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 332:974-77
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5
  • 61
    • 33845864460 scopus 로고    scopus 로고
    • A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2
    • Wang Q, McLoughlin RM, Cobb BA, Charrel-Dennis M, Zaleski KJ, et al. 2006. A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2. J. Exp. Med. 203:2853-63
    • (2006) J. Exp. Med. , vol.203 , pp. 2853-2863
    • Wang, Q.1    McLoughlin, R.M.2    Cobb, B.A.3    Charrel-Dennis, M.4    Zaleski, K.J.5
  • 62
    • 84865134857 scopus 로고    scopus 로고
    • Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice
    • Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, et al. 2012. Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. Cell Host Microbe 12:139-52
    • (2012) Cell Host Microbe , vol.12 , pp. 139-152
    • Carvalho, F.A.1    Koren, O.2    Goodrich, J.K.3    Johansson, M.E.4    Nalbantoglu, I.5
  • 63
    • 84869209695 scopus 로고    scopus 로고
    • The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens
    • Wilson RH, Maruoka S, Whitehead GS, Foley JF, Flake GP, et al. 2012. The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens. Nat. Med. 18:1705-10
    • (2012) Nat. Med. , vol.18 , pp. 1705-1710
    • Wilson, R.H.1    Maruoka, S.2    Whitehead, G.S.3    Foley, J.F.4    Flake, G.P.5
  • 64
    • 84867746584 scopus 로고    scopus 로고
    • Inhibition of TLRsignaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs
    • Yan D, Wang X, Luo L, Cao X, Ge B. 2012. Inhibition of TLRsignaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs. Nat. Immunol. 13:1063-71
    • (2012) Nat. Immunol. , vol.13 , pp. 1063-1071
    • Yan, D.1    Wang, X.2    Luo, L.3    Cao, X.4    Ge, B.5
  • 65
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γand Rel A
    • Kelly D, Campbell JI, King TP, Grant G, Jansson EA, et al. 2004. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γand Rel A. Nat. Immunol. 5:104-12
    • (2004) Nat. Immunol. , vol.5 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3    Grant, G.4    Jansson, E.A.5
  • 66
    • 84873729246 scopus 로고    scopus 로고
    • A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells
    • Klose CS, Kiss EA, Schwierzeck V, Ebert K, Hoyler T, et al. 2013. A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells. Nature 494:261-65
    • (2013) Nature , vol.494 , pp. 261-265
    • Klose, C.S.1    Kiss, E.A.2    Schwierzeck, V.3    Ebert, K.4    Hoyler, T.5
  • 67
    • 84872852300 scopus 로고    scopus 로고
    • The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation
    • Renga B, Mencarelli A, Cipriani S, D'Amore C, Carino A, et al. 2013. The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation. PLoS ONE 8:e54472
    • (2013) PLoS ONE , vol.8
    • Renga, B.1    Mencarelli, A.2    Cipriani, S.3    D'Amore, C.4    Carino, A.5
  • 68
    • 84865305956 scopus 로고    scopus 로고
    • Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity
    • Kidani Y, Bensinger SJ. 2012. Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity. Immunol. Rev. 249:72-83
    • (2012) Immunol. Rev. , vol.249 , pp. 72-83
    • Kidani, Y.1    Bensinger, S.J.2
  • 69
    • 84862303080 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor in inflammatory bowel disease: Linking the environment to disease pathogenesis
    • Monteleone I, MacDonald TT, Pallone F, Monteleone G. 2012. The aryl hydrocarbon receptor in inflammatory bowel disease: linking the environment to disease pathogenesis. Curr. Opin. Gastroenterol. 28:310-13
    • (2012) Curr. Opin. Gastroenterol. , vol.28 , pp. 310-313
    • Monteleone, I.1    MacDonald, T.T.2    Pallone, F.3    Monteleone, G.4
  • 70
    • 84856237141 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells
    • Qiu J, Heller JJ, Guo X, Chen ZM, Fish K, et al. 2012. The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells. Immunity 36:92-104
    • (2012) Immunity , vol.36 , pp. 92-104
    • Qiu, J.1    Heller, J.J.2    Guo, X.3    Chen, Z.M.4    Fish, K.5
  • 71
    • 84856016415 scopus 로고    scopus 로고
    • Diet and intestinal immunity
    • Tilg H. 2012. Diet and intestinal immunity. N. Engl. J. Med. 366:181-83
    • (2012) N. Engl. J. Med. , vol.366 , pp. 181-183
    • Tilg, H.1
  • 72
    • 84871784400 scopus 로고    scopus 로고
    • Gut indigenous microbiota and epigenetics
    • Shenderov BA. 2012. Gut indigenous microbiota and epigenetics. Microb. Ecol. Health Dis. 23:17195
    • (2012) Microb. Ecol. Health Dis. , vol.23 , pp. 17195
    • Shenderov, B.A.1
  • 74
    • 84868158515 scopus 로고    scopus 로고
    • Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice
    • Lawley TD, Clare S, Walker AW, Stares MD, Connor TR, et al. 2012. Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog. 8:e1002995
    • (2012) PLoS Pathog. , vol.8
    • Lawley, T.D.1    Clare, S.2    Walker, A.W.3    Stares, M.D.4    Connor, T.R.5
  • 76
    • 84867057848 scopus 로고    scopus 로고
    • The microbiome and inflammatory bowel disease: Is there a therapeutic role for fecal microbiota transplantation?
    • Damman CJ, Miller SI, Surawicz CM, Zisman TL. 2012. The microbiome and inflammatory bowel disease: Is there a therapeutic role for fecal microbiota transplantation? Am. J. Gastroenterol. 107:1452-59
    • (2012) Am. J. Gastroenterol. , vol.107 , pp. 1452-1459
    • Damman, C.J.1    Miller, S.I.2    Surawicz, C.M.3    Zisman, T.L.4
  • 77
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermudez-Humaran LG, et al. 2008. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc. Natl. Acad. Sci. USA 105:16731-36
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3    Lakhdari, O.4    Bermudez-Humaran, L.G.5
  • 78
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous Clostridium species
    • Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, et al. 2011. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 331:337-41
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3    Imaoka, A.4    Kuwahara, T.5
  • 79
    • 80052122796 scopus 로고    scopus 로고
    • Indigenous Clostridium species regulate systemic immune responses by induction of colonic regulatory T cells
    • Chiba T, Seno H. 2011. Indigenous Clostridium species regulate systemic immune responses by induction of colonic regulatory T cells. Gastroenterology 141:1114-16
    • (2011) Gastroenterology , vol.141 , pp. 1114-1116
    • Chiba, T.1    Seno, H.2
  • 80
    • 84865296650 scopus 로고    scopus 로고
    • The induction of Treg cells by gut-indigenous Clostridium
    • Nagano Y, Itoh K, Honda K. 2012. The induction of Treg cells by gut-indigenous Clostridium. Curr. Opin. Immunol. 24:392-97
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 392-397
    • Nagano, Y.1    Itoh, K.2    Honda, K.3
  • 81
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round JL, Mazmanian SK. 2010. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. USA 107:12204-9
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 82
    • 84873336433 scopus 로고    scopus 로고
    • Evaluation of efficacy of probiotics in prevention of Candida colonization in a PICU-A randomized controlled trial
    • Kumar S, Bansal A, Chakrabarti A, Singhi S. 2013. Evaluation of efficacy of probiotics in prevention of Candida colonization in a PICU-a randomized controlled trial. Crit. Care Med. 41:565-72
    • (2013) Crit. Care Med. , vol.41 , pp. 565-572
    • Kumar, S.1    Bansal, A.2    Chakrabarti, A.3    Singhi, S.4
  • 83
    • 76949107790 scopus 로고    scopus 로고
    • Host interactions of probiotic bacterial surface molecules: Comparison with commensals and pathogens
    • Lebeer S, Vanderleyden J, De Keersmaecker SC. 2010. Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat. Rev. Microbiol. 8:171-84
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 171-184
    • Lebeer, S.1    Vanderleyden, J.2    De Keersmaecker, S.C.3
  • 84
    • 84877136407 scopus 로고    scopus 로고
    • Regulation of intestinal homeostasis and immunity with probiotic lactobacilli
    • van Baarlen P, Wells JM, Kleerebezem M. 2013. Regulation of intestinal homeostasis and immunity with probiotic lactobacilli. Trends Immunol. 34:208-15
    • (2013) Trends Immunol. , vol.34 , pp. 208-215
    • Van Baarlen, P.1    Wells, J.M.2    Kleerebezem, M.3
  • 85
    • 84872158044 scopus 로고    scopus 로고
    • Pre-, pro-, and synbiotics: Do they have a role in reducing uremic toxins? A systematic review and meta-analysis
    • Rossi M, Klein K, Johnson DW, Campbell KL. 2012. Pre-, pro-, and synbiotics: Do they have a role in reducing uremic toxins? A systematic review and meta-analysis. Int. J. Nephrol. 2012:673631
    • (2012) Int. J. Nephrol. , vol.2012 , pp. 673631
    • Rossi, M.1    Klein, K.2    Johnson, D.W.3    Campbell, K.L.4
  • 88
    • 79952664813 scopus 로고    scopus 로고
    • Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid
    • Mohamadzadeh M, Pfeiler EA, Brown JB, Zadeh M, Gramarossa M, et al. 2011. Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc. Natl. Acad. Sci. USA 108(Suppl. 1):4623-30
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , Issue.SUPPL. 1 , pp. 4623-4630
    • Mohamadzadeh, M.1    Pfeiler, E.A.2    Brown, J.B.3    Zadeh, M.4    Gramarossa, M.5
  • 89
    • 84862992817 scopus 로고    scopus 로고
    • Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid
    • Khazaie K, Zadeh M, Khan MW, Bere P, Gounari F, et al. 2012. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc. Natl. Acad. Sci. USA 109:10462-67
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 10462-10467
    • Khazaie, K.1    Zadeh, M.2    Khan, M.W.3    Bere, P.4    Gounari, F.5
  • 90
    • 79952131950 scopus 로고    scopus 로고
    • Vitamin B6 is required for full motility and virulence in Helicobacter pylori
    • Grubman A, Phillips A, Thibonnier M, Kaparakis-Liaskos M, Johnson C, et al. 2010. Vitamin B6 is required for full motility and virulence in Helicobacter pylori. mBio 1(3):e00112-10
    • (2010) MBio , vol.1 , Issue.3
    • Grubman, A.1    Phillips, A.2    Thibonnier, M.3    Kaparakis-Liaskos, M.4    Johnson, C.5
  • 92
    • 0027284172 scopus 로고
    • Selection criteria for lactic acid bacteria to be used as starter cultures for various food commodities
    • Buckenhüskes HJ. 1993. Selection criteria for lactic acid bacteria to be used as starter cultures for various food commodities. FEMS Microbiol. Rev. 12:253-71
    • (1993) FEMS Microbiol. Rev. , vol.12 , pp. 253-271
    • Buckenhüskes, H.J.1
  • 93
    • 0015911351 scopus 로고
    • Microbial contamination of the gut: Another feature of malnutrition
    • Gracey M, Suharjono, Sunoto, Stone DE. 1973. Microbial contamination of the gut: another feature of malnutrition. Am. J. Clin. Nutr. 26:1170-74
    • (1973) Am. J. Clin. Nutr. , vol.26 , pp. 1170-1174
    • Gracey, M.1    Suharjono, S.2    Stone, D.E.3
  • 94
    • 84873875156 scopus 로고    scopus 로고
    • Gutmicrobiomes of Malawian twin pairs discordant for kwashiorkor
    • Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, et al. 2013. Gutmicrobiomes of Malawian twin pairs discordant for kwashiorkor. Science 339:548-54
    • (2013) Science , vol.339 , pp. 548-554
    • Smith, M.I.1    Yatsunenko, T.2    Manary, M.J.3    Trehan, I.4    Mkakosya, R.5
  • 95
    • 0033935339 scopus 로고    scopus 로고
    • The consequences of diarrhea occurring during chemotherapy for colorectal cancer: A retrospective study
    • Arbuckle RB, Huber SL, Zacker C. 2000. The consequences of diarrhea occurring during chemotherapy for colorectal cancer: a retrospective study. Oncologist 5:250-59
    • (2000) Oncologist , vol.5 , pp. 250-259
    • Arbuckle, R.B.1    Huber, S.L.2    Zacker, C.3
  • 98
    • 52049119905 scopus 로고    scopus 로고
    • Evaluation and management of treatment-related diarrhea in patients with advanced cancer: A review
    • Cherny NI. 2008. Evaluation and management of treatment-related diarrhea in patients with advanced cancer: a review. J. Pain Symptom Manag. 36:413-23
    • (2008) J. Pain Symptom Manag. , vol.36 , pp. 413-423
    • Cherny, N.I.1
  • 99
    • 15344346124 scopus 로고    scopus 로고
    • Estimating the cost of illness in colorectal cancer patients who were hospitalized for severe chemotherapy-induced diarrhea
    • Dranitsaris G, Maroun J, Shah A. 2005. Estimating the cost of illness in colorectal cancer patients who were hospitalized for severe chemotherapy-induced diarrhea. Can. J. Gastroenterol. 19:83-87
    • (2005) Can. J. Gastroenterol. , vol.19 , pp. 83-87
    • Dranitsaris, G.1    Maroun, J.2    Shah, A.3
  • 100
    • 18744409081 scopus 로고    scopus 로고
    • Severe chemotherapy-induced diarrhea in patients with colorectal cancer: A cost of illness analysis
    • Dranitsaris G, Maroun J, Shah A. 2005. Severe chemotherapy-induced diarrhea in patients with colorectal cancer: a cost of illness analysis. Support. Care Cancer 13:318-24
    • (2005) Support. Care Cancer , vol.13 , pp. 318-324
    • Dranitsaris, G.1    Maroun, J.2    Shah, A.3
  • 102
    • 77953395957 scopus 로고    scopus 로고
    • Chemotherapy-induced diarrhea: Pathophysiology, frequency and guideline-based management
    • Stein A, Voigt W, Jordan K. 2010. Chemotherapy-induced diarrhea: pathophysiology, frequency and guideline-based management. Ther. Adv. Med. Oncol. 2:51-63
    • (2010) Ther. Adv. Med. Oncol. , vol.2 , pp. 51-63
    • Stein, A.1    Voigt, W.2    Jordan, K.3
  • 103
    • 0037380607 scopus 로고    scopus 로고
    • Intestinal ion transport and the pathophysiology of diarrhea
    • Field M. 2003. Intestinal ion transport and the pathophysiology of diarrhea. J. Clin. Investig. 111:931-43
    • (2003) J. Clin. Investig. , vol.111 , pp. 931-943
    • Field, M.1
  • 104
    • 0035884212 scopus 로고    scopus 로고
    • Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: Summary findings of an independent panel
    • Rothenberg ML, Meropol NJ, Poplin EA, Van Cutsem E, Wadler S. 2001. Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel. J. Clin. Oncol. 19:3801-7
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3801-3807
    • Rothenberg, M.L.1    Meropol, N.J.2    Poplin, E.A.3    Van Cutsem, E.4    Wadler, S.5
  • 105
    • 67349177047 scopus 로고    scopus 로고
    • Current place of high-dose irinotecan chemotherapy in patients with metastatic colorectal cancer
    • Hebbar M, Ychou M, Ducreux M. 2009. Current place of high-dose irinotecan chemotherapy in patients with metastatic colorectal cancer. J. Cancer Res. Clin. Oncol. 135:749-52
    • (2009) J. Cancer Res. Clin. Oncol. , vol.135 , pp. 749-752
    • Hebbar, M.1    Ychou, M.2    Ducreux, M.3
  • 106
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
    • Gupta E, Lestingi TM, Mick R, Ramirez J, Vokes EE, Ratain MJ. 1994. Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res. 54:3723-25
    • (1994) Cancer Res. , vol.54 , pp. 3723-3725
    • Gupta, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Vokes, E.E.5    Ratain, M.J.6
  • 107
    • 0027242140 scopus 로고
    • Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood plasma of athymic mice following intraperitoneal administration of CPT-11
    • Araki E, Ishikawa M, Iigo M, Koide T, Itabashi M, Hoshi A. 1993. Relationship between development of diarrhea and the concentration of SN-38, an active metabolite of CPT-11, in the intestine and the blood plasma of athymic mice following intraperitoneal administration of CPT-11. Jpn. J. Cancer Res. 84:697-702
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 697-702
    • Araki, E.1    Ishikawa, M.2    Iigo, M.3    Koide, T.4    Itabashi, M.5    Hoshi, A.6
  • 109
    • 0023747871 scopus 로고
    • The importance of dose intensity in the outcome of chemotherapy
    • Hryniuk W. 1988. The importance of dose intensity in the outcome of chemotherapy. Important Adv. Oncol. 1988:121-41
    • (1988) Important Adv. Oncol. , vol.1988 , pp. 121-141
    • Hryniuk, W.1
  • 110
    • 0028346901 scopus 로고
    • Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea
    • Abigerges D, Armand JP, Chabot GG, Da Costa L, Fadel E, et al. 1994. Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea. J. Natl. Cancer Inst. 86:446-49
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 446-449
    • Abigerges, D.1    Armand, J.P.2    Chabot, G.G.3    Da Costa, L.4    Fadel, E.5
  • 111
    • 4444241175 scopus 로고    scopus 로고
    • New approaches to prevent intestinal toxicity of irinotecan-based regimens
    • Alimonti A, Gelibter A, Pavese I, Satta F, Cognetti F, et al. 2004. New approaches to prevent intestinal toxicity of irinotecan-based regimens. Cancer Treat. Rev. 30:555-62
    • (2004) Cancer Treat. Rev. , vol.30 , pp. 555-562
    • Alimonti, A.1    Gelibter, A.2    Pavese, I.3    Satta, F.4    Cognetti, F.5
  • 113
    • 0031947166 scopus 로고    scopus 로고
    • Octreotide does not prevent diarrhea in patients treated with weekly 5-fluorouracil plus high-dose leucovorin
    • Meropol NJ, Blumenson LE, Creaven PJ. 1998. Octreotide does not prevent diarrhea in patients treated with weekly 5-fluorouracil plus high-dose leucovorin. Am. J. Clin. Oncol. 21:135-38
    • (1998) Am. J. Clin. Oncol. , vol.21 , pp. 135-138
    • Meropol, N.J.1    Blumenson, L.E.2    Creaven, P.J.3
  • 114
    • 4043152968 scopus 로고    scopus 로고
    • Resolution of refractory chemotherapy-induced diarrhea (CID) with octreotide longacting formulation in cancer patients: 11 case studies
    • Rosenoff S. 2004. Resolution of refractory chemotherapy-induced diarrhea (CID) with octreotide longacting formulation in cancer patients: 11 case studies. Support. Care Cancer 12:561-70
    • (2004) Support. Care Cancer , vol.12 , pp. 561-570
    • Rosenoff, S.1
  • 115
    • 33748529958 scopus 로고    scopus 로고
    • Prophylaxis of irinotecaninduced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: A double-blind, randomized, placebo-controlled study
    • de Jong FA, Kehrer DF, Mathijssen RH, Creemers GJ, de Bruijn P, et al. 2006. Prophylaxis of irinotecaninduced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study. Oncologist 11:944-54
    • (2006) Oncologist , vol.11 , pp. 944-954
    • De Jong, F.A.1    Kehrer, D.F.2    Mathijssen, R.H.3    Creemers, G.J.4    De Bruijn, P.5
  • 116
    • 0034901949 scopus 로고    scopus 로고
    • Modulation of irinotecaninduced diarrhea by cotreatment with neomycin in cancer patients
    • Kehrer DF, Sparreboom A, Verweij J, de Bruijn P, Nierop CA, et al. 2001. Modulation of irinotecaninduced diarrhea by cotreatment with neomycin in cancer patients. Clin. Cancer Res. 7:1136-41
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1136-1141
    • Kehrer, D.F.1    Sparreboom, A.2    Verweij, J.3    De Bruijn, P.4    Nierop, C.A.5
  • 117
    • 37049006270 scopus 로고    scopus 로고
    • Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal carcinoma
    • Flieger D, Klassert C, Hainke S, Keller R, Kleinschmidt R, Fischbach W. 2007. Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal carcinoma. Oncology 72:10-16
    • (2007) Oncology , vol.72 , pp. 10-16
    • Flieger, D.1    Klassert, C.2    Hainke, S.3    Keller, R.4    Kleinschmidt, R.5    Fischbach, W.6
  • 118
    • 4444244550 scopus 로고    scopus 로고
    • Neomycin as secondary prophylaxis for irinotecaninduced diarrhea
    • Schmittel A, Jahnke K, Thiel E, Keilholz U. 2004. Neomycin as secondary prophylaxis for irinotecaninduced diarrhea. Ann. Oncol. 15:1296
    • (2004) Ann. Oncol. , vol.15 , pp. 1296
    • Schmittel, A.1    Jahnke, K.2    Thiel, E.3    Keilholz, U.4
  • 119
    • 1942438132 scopus 로고    scopus 로고
    • Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity
    • Zhao J, Huang L, Belmar N, Buelow R, Fong T. 2004. Oral RDP58 allows CPT-11 dose intensification for enhanced tumor response by decreasing gastrointestinal toxicity. Clin. Cancer Res. 10:2851-59
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2851-2859
    • Zhao, J.1    Huang, L.2    Belmar, N.3    Buelow, R.4    Fong, T.5
  • 121
    • 42249108725 scopus 로고    scopus 로고
    • DTS-108, a novel peptidic prodrug of SN38: In vivo efficacy and toxicokinetic studies
    • Meyer-Losic F, Nicolazzi C, Quinonero J, Ribes F, Michel M, et al. 2008. DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies. Clin. Cancer Res. 14:2145-53
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2145-2153
    • Meyer-Losic, F.1    Nicolazzi, C.2    Quinonero, J.3    Ribes, F.4    Michel, M.5
  • 122
    • 67549128953 scopus 로고    scopus 로고
    • Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity
    • Hicks LD, Hyatt JL, Stoddard S, Tsurkan L, Edwards CC, et al. 2009. Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity. J. Med. Chem. 52:3742-52
    • (2009) J. Med. Chem. , vol.52 , pp. 3742-3752
    • Hicks, L.D.1    Hyatt, J.L.2    Stoddard, S.3    Tsurkan, L.4    Edwards, C.C.5
  • 123
    • 74549146691 scopus 로고    scopus 로고
    • Antitumor effect of NK012, a 7-ethyl-10-hydroxycamptothecin-incorporating polymeric micelle, on U87MG orthotopic glioblastoma in mice compared with irinotecan hydrochloride in combination with bevacizumab
    • Kuroda J, Kuratsu J, Yasunaga M, Koga Y, Kenmotsu H, et al. 2010. Antitumor effect of NK012, a 7-ethyl-10-hydroxycamptothecin-incorporating polymeric micelle, on U87MG orthotopic glioblastoma in mice compared with irinotecan hydrochloride in combination with bevacizumab. Clin. Cancer Res. 16:521-29
    • (2010) Clin. Cancer Res. , vol.16 , pp. 521-529
    • Kuroda, J.1    Kuratsu, J.2    Yasunaga, M.3    Koga, Y.4    Kenmotsu, H.5
  • 125
    • 0037238805 scopus 로고    scopus 로고
    • Lessons learned from the irinotecan metabolic pathway
    • Ma MK, McLeod HL. 2003. Lessons learned from the irinotecan metabolic pathway. Curr. Med. Chem. 10:41-49
    • (2003) Curr. Med. Chem. , vol.10 , pp. 41-49
    • Ma, M.K.1    McLeod, H.L.2
  • 126
    • 0029089278 scopus 로고
    • Limited sampling models for simultaneous estimation of the pharmacokinetics of irinotecan and its active metabolite SN-38
    • Chabot GG. 1995. Limited sampling models for simultaneous estimation of the pharmacokinetics of irinotecan and its active metabolite SN-38. Cancer Chemother. Pharmacol. 36:463-72
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 463-472
    • Chabot, G.G.1
  • 127
    • 0030469167 scopus 로고    scopus 로고
    • Clinical pharmacology and pharmacodynamics of irinotecan. A review
    • Chabot GG. 1996. Clinical pharmacology and pharmacodynamics of irinotecan. A review. Ann. N. Y. Acad. Sci. 803:164-72
    • (1996) Ann. N. Y. Acad. Sci. , vol.803 , pp. 164-172
    • Chabot, G.G.1
  • 128
    • 77957892163 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drug-related injury to the gastrointestinal tract: Clinical picture, pathogenesis, and prevention
    • Scarpignato C, Hunt RH. 2010. Nonsteroidal antiinflammatory drug-related injury to the gastrointestinal tract: clinical picture, pathogenesis, and prevention. Gastroenterol. Clin. N. Am. 39:433-64
    • (2010) Gastroenterol. Clin. N. Am. , vol.39 , pp. 433-464
    • Scarpignato, C.1    Hunt, R.H.2
  • 129
    • 84894259542 scopus 로고    scopus 로고
    • Gastrointestinal safety of NSAIDs and over-The-counter analgesics
    • Bjarnason I. 2013. Gastrointestinal safety of NSAIDs and over-the-counter analgesics. Int. J. Clin. Pract. 67(Suppl. 178):37-42
    • (2013) Int. J. Clin. Pract. , vol.67 , Issue.SUPPL. 178 , pp. 37-42
    • Bjarnason, I.1
  • 130
    • 33846651838 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and the small intestine
    • Fortun PJ, Hawkey CJ. 2007. Nonsteroidal antiinflammatory drugs and the small intestine. Curr. Opin. Gastroenterol. 23:134-41
    • (2007) Curr. Opin. Gastroenterol. , vol.23 , pp. 134-141
    • Fortun, P.J.1    Hawkey, C.J.2
  • 131
    • 58849140520 scopus 로고    scopus 로고
    • Capsule endoscopic diagnosis of nonsteroidal antiinflammatory drug-induced enteropathy
    • Maiden L. 2009. Capsule endoscopic diagnosis of nonsteroidal antiinflammatory drug-induced enteropathy. J. Gastroenterol. 44:64-71
    • (2009) J. Gastroenterol. , vol.44 , pp. 64-71
    • Maiden, L.1
  • 132
    • 82955184551 scopus 로고    scopus 로고
    • NSAID gastropathy and enteropathy: Distinct pathogenesis likely necessitates distinct prevention strategies
    • Wallace JL. 2012. NSAID gastropathy and enteropathy: Distinct pathogenesis likely necessitates distinct prevention strategies. Br. J. Clin. Pharmacol. 165:67-74
    • (2012) Br. J. Clin. Pharmacol. , vol.165 , pp. 67-74
    • Wallace, J.L.1
  • 133
    • 84873854068 scopus 로고    scopus 로고
    • Multiple NSAID-induced hits injure the small intestine: Underlying mechanisms and novel strategies
    • Boelsterli UA, Redinbo MR, Saitta K. 2013. Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies. Toxicol. Sci. 131:654-67
    • (2013) Toxicol. Sci. , vol.131 , pp. 654-667
    • Boelsterli, U.A.1    Redinbo, M.R.2    Saitta, K.3
  • 134
    • 84855447409 scopus 로고    scopus 로고
    • Diclofenac metabolism in the mouse: Novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry
    • Sarda S, Page C, Pickup K, Schulz-Utermoehl T, Wilson I. 2012. Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry. Xenobiotica 42:179-94
    • (2012) Xenobiotica , vol.42 , pp. 179-194
    • Sarda, S.1    Page, C.2    Pickup, K.3    Schulz-Utermoehl, T.4    Wilson, I.5
  • 135
    • 0031844523 scopus 로고    scopus 로고
    • Oxidation of a metabolite of indomethacin (desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system
    • Ju C, Uetrecht J. 1998. Oxidation of a metabolite of indomethacin (desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system. Drug Metab. Dispos. 26:676-80
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 676-680
    • Ju, C.1    Uetrecht, J.2
  • 136
    • 0014468568 scopus 로고
    • Small intestinal ulcers and intestinal flora in rats given indomethacin
    • Kent TH, Cardelli RM, Stamler FW. 1969. Small intestinal ulcers and intestinal flora in rats given indomethacin. Am. J. Pathol. 54:237-48
    • (1969) Am. J. Pathol. , vol.54 , pp. 237-248
    • Kent, T.H.1    Cardelli, R.M.2    Stamler, F.W.3
  • 137
    • 0017690751 scopus 로고
    • Resistance of germfree rats to indomethacin-induced intestinal lesions
    • Robert A, Asano T. 1977. Resistance of germfree rats to indomethacin-induced intestinal lesions. Prostaglandins 14:333-41
    • (1977) Prostaglandins , vol.14 , pp. 333-341
    • Robert, A.1    Asano, T.2
  • 138
    • 0029787769 scopus 로고    scopus 로고
    • Role of intestinal bacteria in ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug
    • Uejima M, Kinouchi T, Kataoka K, Hiraoka I, Ohnishi Y. 1996. Role of intestinal bacteria in ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug. Microbiol. Immunol. 40:553-60
    • (1996) Microbiol. Immunol. , vol.40 , pp. 553-560
    • Uejima, M.1    Kinouchi, T.2    Kataoka, K.3    Hiraoka, I.4    Ohnishi, Y.5
  • 139
    • 0015991231 scopus 로고
    • Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract
    • Tannock GW, Savage DC. 1974. Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract. Infect. Immun. 9:591-98
    • (1974) Infect. Immun. , vol.9 , pp. 591-598
    • Tannock, G.W.1    Savage, D.C.2
  • 140
    • 0031014088 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug enteropathy in rats: Role of permeability, bacteria, and enterohepatic circulation
    • Reuter BK, Davies NM, Wallace JL. 1997. Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation. Gastroenterology 112:109-17
    • (1997) Gastroenterology , vol.112 , pp. 109-117
    • Reuter, B.K.1    Davies, N.M.2    Wallace, J.L.3
  • 141
    • 0036201140 scopus 로고    scopus 로고
    • Experimental studies on synergism between aminoglycosides and the antimicrobial antiinflammatory agent diclofenac sodium
    • Annadurai S, Guha-Thakurta A, Sa B, Dastidar SG, Ray R, Chakrabarty AN. 2002. Experimental studies on synergism between aminoglycosides and the antimicrobial antiinflammatory agent diclofenac sodium. J. Chemother. 14:47-53
    • (2002) J. Chemother. , vol.14 , pp. 47-53
    • Annadurai, S.1    Guha-Thakurta, A.2    Sa, B.3    Dastidar, S.G.4    Ray, R.5    Chakrabarty, A.N.6
  • 143
    • 0036113986 scopus 로고    scopus 로고
    • Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/CD18 and CD11b/CD18 co-dependent
    • Stadnyk AW, Dollard C, Issekutz TB, Issekutz AC. 2002. Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/CD18 and CD11b/CD18 co-dependent. Gut 50:629-35
    • (2002) Gut , vol.50 , pp. 629-635
    • Stadnyk, A.W.1    Dollard, C.2    Issekutz, T.B.3    Issekutz, A.C.4
  • 144
    • 38549158018 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent
    • Watanabe T, Higuchi K, Kobata A, Nishio H, Tanigawa T, et al. 2008. Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent. Gut 57:181-87
    • (2008) Gut , vol.57 , pp. 181-187
    • Watanabe, T.1    Higuchi, K.2    Kobata, A.3    Nishio, H.4    Tanigawa, T.5
  • 145
    • 50249137214 scopus 로고    scopus 로고
    • Protective effect of octreotide and infliximab in an experimental model of indomethacin-induced inflammatory bowel disease
    • Cury DH, Costa JE, Irika K, Mijji L, Garcez A, et al. 2008. Protective effect of octreotide and infliximab in an experimental model of indomethacin-induced inflammatory bowel disease. Dig. Dis. Sci. 53:2516-20
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 2516-2520
    • Cury, D.H.1    Costa, J.E.2    Irika, K.3    Mijji, L.4    Garcez, A.5
  • 146
    • 79551588521 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in mice
    • Fukumoto K, Naito Y, Takagi T, Yamada S, Horie R, et al. 2011. Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in mice. Int. J. Mol. Med. 27:353-59
    • (2011) Int. J. Mol. Med. , vol.27 , pp. 353-359
    • Fukumoto, K.1    Naito, Y.2    Takagi, T.3    Yamada, S.4    Horie, R.5
  • 147
    • 0032763157 scopus 로고    scopus 로고
    • Roles of enterobacteria, nitric oxide and neutrophil in the pathogenesis of indomethacin-induced small intestinal lesions in rats
    • Konaka A, Kato S, Tanaka A, Kunikata T, Korolkiewicz R, Takeuchi K. 1999. Roles of enterobacteria, nitric oxide and neutrophil in the pathogenesis of indomethacin-induced small intestinal lesions in rats. Pharmacol. Res. 40:517-24
    • (1999) Pharmacol. Res. , vol.40 , pp. 517-524
    • Konaka, A.1    Kato, S.2    Tanaka, A.3    Kunikata, T.4    Korolkiewicz, R.5    Takeuchi, K.6
  • 148
    • 80054122238 scopus 로고    scopus 로고
    • The antibacterial lectin RegIIIγ promotes the spatial segregation of microbiota and host in the intestine
    • Vaishnava S, Yamamoto M, Severson KM, Ruhn KA, Yu X, et al. 2011. The antibacterial lectin RegIIIγ promotes the spatial segregation of microbiota and host in the intestine. Science 334:255-58
    • (2011) Science , vol.334 , pp. 255-258
    • Vaishnava, S.1    Yamamoto, M.2    Severson, K.M.3    Ruhn, K.A.4    Yu, X.5
  • 149
    • 46049093197 scopus 로고    scopus 로고
    • A new role for intestinal alkaline phosphatase in gut barrier maintenance
    • Geddes K, Philpot DJ. 2008. A new role for intestinal alkaline phosphatase in gut barrier maintenance. Gastroenterology 135:8-12
    • (2008) Gastroenterology , vol.135 , pp. 8-12
    • Geddes, K.1    Philpot, D.J.2
  • 150
    • 0027173682 scopus 로고
    • Mutagenicity of the bile of dogs with an experimental model of an anomalous arrangement of the pancreaticobiliary duct
    • Qian D, Kinouchi T, Kunitoomo K, Kataoka K, Abdul Matin M, et al. 1993. Mutagenicity of the bile of dogs with an experimental model of an anomalous arrangement of the pancreaticobiliary duct. Carcinogenesis 14:743-47
    • (1993) Carcinogenesis , vol.14 , pp. 743-747
    • Qian, D.1    Kinouchi, T.2    Kunitoomo, K.3    Kataoka, K.4    Abdul Matin, M.5
  • 151
    • 55949136053 scopus 로고    scopus 로고
    • Distribution of β-glucosidase and β- Glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria
    • Dabek M, McCrae SI, Stevens VJ, Duncan SH, Louis P. 2008. Distribution of β-glucosidase and β- glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria. FEMS Microbiol. Ecol. 66:487-95
    • (2008) FEMS Microbiol. Ecol. , vol.66 , pp. 487-495
    • Dabek, M.1    McCrae, S.I.2    Stevens, V.J.3    Duncan, S.H.4    Louis, P.5
  • 152
    • 0025057187 scopus 로고
    • Metabolism of drugs and other xenobiotics in the gut lumen and wall
    • Ilett KF, Tee LB, Reeves PT, Minchin RF. 1990. Metabolism of drugs and other xenobiotics in the gut lumen and wall. Pharmacol. Ther. 46:67-93
    • (1990) Pharmacol. Ther. , vol.46 , pp. 67-93
    • Ilett, K.F.1    Tee, L.B.2    Reeves, P.T.3    Minchin, R.F.4
  • 153
    • 0027449074 scopus 로고
    • In vitro evaluation of dexamethasone-β-Dglucuronide for colon-specific drug delivery
    • Haeberlin B, Rubas W, Nolen HW, Friend DR. 1993. In vitro evaluation of dexamethasone-β-Dglucuronide for colon-specific drug delivery. Pharm. Res. 10:1553-62
    • (1993) Pharm. Res. , vol.10 , pp. 1553-1562
    • Haeberlin, B.1    Rubas, W.2    Nolen, H.W.3    Friend, D.R.4
  • 154
    • 84855900973 scopus 로고    scopus 로고
    • Use of physiologically based pharmacokinetic models to evaluate the impact of intestinal glucuronide hydrolysis on the pharmacokinetics of aglycone
    • Wu B. 2012. Use of physiologically based pharmacokinetic models to evaluate the impact of intestinal glucuronide hydrolysis on the pharmacokinetics of aglycone. J. Pharm. Sci. 101:1281-301
    • (2012) J. Pharm. Sci. , vol.101 , pp. 1281-1301
    • Wu, B.1
  • 155
    • 33644531928 scopus 로고    scopus 로고
    • Microbial flora in NSAID-induced intestinal damage: A role for antibiotics?
    • Lanas A, Scarpignato C. 2006. Microbial flora in NSAID-induced intestinal damage: a role for antibiotics? Digestion 73(Suppl. 1):136-50
    • (2006) Digestion , vol.73 , Issue.SUPPL. 1 , pp. 136-150
    • Lanas, A.1    Scarpignato, C.2
  • 157
    • 84867719407 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs-induced small intestinal injury and probiotic agents
    • Guslandi M. 2012. Non-steroidal anti-inflammatory drugs-induced small intestinal injury and probiotic agents. World J. Gastroenterol. 18:4241-42
    • (2012) World J. Gastroenterol. , vol.18 , pp. 4241-4242
    • Guslandi, M.1
  • 158
    • 84859987078 scopus 로고    scopus 로고
    • Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice
    • LoGuidice A, Wallace BD, Bendel L, Redinbo MR, Boelsterli UA. 2012. Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice. J. Pharmacol. Exp. Ther. 341:447-54
    • (2012) J. Pharmacol. Exp. Ther. , vol.341 , pp. 447-454
    • Loguidice, A.1    Wallace, B.D.2    Bendel, L.3    Redinbo, M.R.4    Boelsterli, U.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.