Oxidation of a metabolite of indomethacin (desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system

Drug Metabolism and Disposition

Volumn 26, Issue 7, 1998, Pages 676-680

  Ju, C ^b   Uetrecht, J P ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; HYPOCHLOROUS ACID; INDOMETACIN; MYELOPEROXIDASE; NORDESCHLOROBENZOYLINDOMETHACIN; UNCLASSIFIED DRUG;

AGRANULOCYTOSIS; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG OXIDATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; NEUTROPHIL; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DEXAMETHASONE; HUMANS; HYPOCHLOROUS ACID; NEUTROPHILS; OXIDATION-REDUCTION; PEROXIDASE;

EID: 0031844523     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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