메뉴 건너뛰기




Volumn 288, Issue 2, 2013, Pages 1079-1087

Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo

Author keywords

[No Author keywords available]

Indexed keywords

C-JUN N-TERMINAL KINASE; CELL-PERMEABLE PEPTIDES; IN-VITRO; IN-VIVO; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL TRANSLOCATION; NEUROPROTECTION; NEUROPROTECTIVE AGENTS; NEUROTOXICITY; OUTER MITOCHONDRIAL MEMBRANES; PARKINSON DISEASE; SUBSTANTIA NIGRA; TYROSINE HYDROXYLASE;

EID: 84872356254     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.421354     Document Type: Article
Times cited : (59)

References (23)
  • 1
    • 0037155837 scopus 로고    scopus 로고
    • Direct activation of mitochondrial apoptosis machinery by c-Jun n-terminal kinase in adult cardiac myocytes
    • DOI 10.1074/jbc.M112355200
    • Aoki, H., Kang, P. M., Hampe, J., Yoshimura, K., Noma, T., Matsuzaki, M., and Izumo, S. (2002) Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J. Biol. Chem. 277, 10244-10250 (Pubitemid 34968139)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.12 , pp. 10244-10250
    • Aoki, H.1    Kang, P.M.2    Hampe, J.3    Yoshimura, K.4    Noma, T.5    Matsuzaki, M.6    Izumo, S.7
  • 2
    • 46649084880 scopus 로고    scopus 로고
    • Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury
    • Hanawa, N., Shinohara, M., Saberi, B., Gaarde, W. A., Han, D., and Kaplowitz, N. (2008) Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury. J. Biol. Chem. 283, 13565-13577
    • (2008) J. Biol. Chem. , vol.283 , pp. 13565-13577
    • Hanawa, N.1    Shinohara, M.2    Saberi, B.3    Gaarde, W.A.4    Han, D.5    Kaplowitz, N.6
  • 3
    • 67349094513 scopus 로고    scopus 로고
    • Cerebral ischemia provokes a profound exchange of activated JNK isoforms in brain mitochondria
    • Zhao, Y., and Herdegen, T. (2009) Cerebral ischemia provokes a profound exchange of activated JNK isoforms in brain mitochondria. Mol. Cell. Neurosci. 41, 186-195
    • (2009) Mol. Cell. Neurosci. , vol.41 , pp. 186-195
    • Zhao, Y.1    Herdegen, T.2
  • 4
    • 37349081929 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons
    • DOI 10.1111/j.1471-4159.2007.04957.x
    • Zhou, Q., Lam, P. Y., Han, D., and Cadenas, E. (2008) c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J. Neurochem. 104, 325-335 (Pubitemid 350293865)
    • (2008) Journal of Neurochemistry , vol.104 , Issue.2 , pp. 325-335
    • Zhou, Q.1    Lam, P.Y.2    Han, D.3    Cadenas, E.4
  • 5
    • 62849111251 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging
    • Zhou, Q., Lam, P. Y., Han, D., and Cadenas, E. (2009) Activation of c-Jun N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging. FEBS Lett. 583, 1132-1140
    • (2009) FEBS Lett. , vol.583 , pp. 1132-1140
    • Zhou, Q.1    Lam, P.Y.2    Han, D.3    Cadenas, E.4
  • 6
    • 79955544880 scopus 로고    scopus 로고
    • Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation
    • Chambers, J. W., and LoGrasso, P. V. (2011) Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. J. Biol. Chem. 286, 16052-16062
    • (2011) J. Biol. Chem. , vol.286 , pp. 16052-16062
    • Chambers, J.W.1    LoGrasso, P.V.2
  • 8
    • 20744435383 scopus 로고    scopus 로고
    • Molecular pathophysiology of Parkinson's disease
    • DOI 10.1146/annurev.neuro.28.061604.135718
    • Moore, D. J., West, A. B., Dawson, V. L., and Dawson, T. M. (2005) Molecular pathophysiology of Parkinson's disease. Annu. Rev. Neurosci. 28, 57-87 (Pubitemid 41098899)
    • (2005) Annual Review of Neuroscience , vol.28 , pp. 57-87
    • Moore, D.J.1    West, A.B.2    Dawson, V.L.3    Dawson, T.M.4
  • 11
    • 79955080679 scopus 로고    scopus 로고
    • JNK inhibition protects dopamine neurons and provides behavioral improvement in a rat 6-hydroxydopamine model of Parkinson's disease
    • Crocker, C. E., Khan, S., Cameron, M. D., Robertson, H. A., Robertson, G. S., and Lograsso, P. (2011) JNK inhibition protects dopamine neurons and provides behavioral improvement in a rat 6-hydroxydopamine model of Parkinson's disease. ACS Chem. Neurosci. 2, 207-212
    • (2011) ACS Chem. Neurosci. , vol.2 , pp. 207-212
    • Crocker, C.E.1    Khan, S.2    Cameron, M.D.3    Robertson, H.A.4    Robertson, G.S.5    Lograsso, P.6
  • 14
    • 0036845859 scopus 로고    scopus 로고
    • A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria
    • DOI 10.1042/BJ20020553
    • Wiltshire, C., Matsushita, M., Tsukada, S., Gillespie, D. A., and May, G. H. (2002) A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria. Biochem. J. 367, 577-585 (Pubitemid 35305698)
    • (2002) Biochemical Journal , vol.367 , Issue.3 , pp. 577-585
    • Wiltshire, C.1    Matsushita, M.2    Tsukada, S.3    Gillespie, D.A.F.4    May, G.H.W.5
  • 15
    • 4344576752 scopus 로고    scopus 로고
    • The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK
    • DOI 10.1074/jbc.M402181200
    • Barr, R. K., Boehm, I., Attwood, P. V., Watt, P. M., and Bogoyevitch, M. A. (2004) The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK. J. Biol. Chem. 279, 36327-36338 (Pubitemid 39128970)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 36327-36338
    • Barr, R.K.1    Boehm, I.2    Attwood, P.V.3    Watt, P.M.4    Bogoyevitch, M.A.5
  • 16
    • 0037192843 scopus 로고    scopus 로고
    • Identification of the critical features of a small peptide inhibitor of JNK activity
    • DOI 10.1074/jbc.M107565200
    • Barr, R. K., Kendrick, T. S., and Bogoyevitch, M. A. (2002) Identification of the critical features of a small peptide inhibitor of JNK activity. J. Biol. Chem. 277, 10987-10997 (Pubitemid 34952855)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.13 , pp. 10987-10997
    • Barr, R.K.1    Kendrick, T.S.2    Bogoyevitch, M.A.3
  • 18
    • 33744959530 scopus 로고    scopus 로고
    • Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases
    • DOI 10.1074/jbc.M601010200
    • Ho, D. T., Bardwell, A. J., Grewal, S., Iverson, C., and Bardwell, L. (2006) Interacting JNK-docking sites inMKK7promote binding and activation of JNK mitogen-activated protein kinases. J. Biol. Chem. 281, 13169-13179 (Pubitemid 43855228)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.19 , pp. 13169-13179
    • Ho, D.T.1    Bardwell, A.J.2    Grewal, S.3    Iverson, C.4    Bardwell, L.5
  • 21
    • 80051999961 scopus 로고    scopus 로고
    • Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1)
    • Chambers, J. W., Cherry, L., Laughlin, J. D., Figuera-Losada, M., and Lograsso, P. V. (2011) Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1). ACS Chem. Biol. 6, 808-818
    • (2011) ACS Chem. Biol. , vol.6 , pp. 808-818
    • Chambers, J.W.1    Cherry, L.2    Laughlin, J.D.3    Figuera-Losada, M.4    Lograsso, P.V.5
  • 22
    • 35748946322 scopus 로고    scopus 로고
    • Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease
    • DOI 10.1016/j.neulet.2007.09.032, PII S0304394007010117
    • Pan, J., Zhao, Y. X., Wang, Z. Q., Jin, L., Sun, Z. K., and Chen, S. D. (2007) Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease. Neurosci. Lett. 428, 82-87 (Pubitemid 350051174)
    • (2007) Neuroscience Letters , vol.428 , Issue.2-3 , pp. 82-87
    • Pan, J.1    Zhao, Y.-x.2    Wang, Z.-Q.3    Jin, L.4    Sun, Z.-K.5    Chen, S.-D.6
  • 23
    • 0035187383 scopus 로고    scopus 로고
    • Injury induced c-Jun expression and phosphorylation in the dopaminergic nigral neurons of the rat: Correlation with neuronal death and modulation by glial-cell-line-derived neurotrophic factor
    • DOI 10.1046/j.1460-9568.2001.01356.x
    • Vaudano, E., Rosenblad, C., and Björklund, A. (2001) Injury induced c-Jun expression and phosphorylation in the dopaminergic nigral neurons of the rat. Correlation with neuronal death and modulation by glial-cell-line-derived neurotrophic factor. Eur. J. Neurosci. 13, 1-14 (Pubitemid 32055862)
    • (2001) European Journal of Neuroscience , vol.13 , Issue.1 , pp. 1-14
    • Vaudano, E.1    Rosenblad, C.2    Bjorklund, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.