Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 9441-9447

  Servant, Marc J ^a,b   Grandvaux, Nathalie ^a,b   TenOever, Benjamin R ^a,b   Duguay, Delphine ^a,b   Lin, Rongtuan ^a,b   Hiscott, John ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; GENES; MUTAGENESIS; VIRUSES;

PHOSPHORYLATION;

RNA;

ALPHA1 INTERFERON; ANTIBODY; BETA INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOUBLE STRANDED RNA; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; POLYPEPTIDE; PROTEIN P300; RANTES; SERINE; TOLL LIKE RECEPTOR 4; ALPHA INTERFERON; ASPARTIC ACID; CCAAT ENHANCER BINDING PROTEIN; CELL SURFACE RECEPTOR; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; INTERFERON ALPHA-1; IRF3 PROTEIN, HUMAN; LUCIFERASE; MEMBRANE PROTEIN; THREONINE; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EMBRYO; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VIRUS INFECTION; AMINO ACID SEQUENCE; BINDING SITE; CELL CULTURE; CELL LINE; CELL STRAIN U937; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; PLASMID; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENDAI VIRUS; SITE DIRECTED MUTAGENESIS; TIME; TRANSACTIVATION;

SENDAI VIRUS;

AMINO ACID SEQUENCE; ASPARTIC ACID; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOBLOTTING; INTERFERON REGULATORY FACTOR-3; INTERFERON-ALPHA; INTERFERON-BETA; LIPOPOLYSACCHARIDES; LUCIFERASES; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORYLATION; PLASMIDS; POINT MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RANTES; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, DOUBLE-STRANDED; SENDAI VIRUS; SERINE; THREONINE; TIME FACTORS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0038660668     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209851200     Document Type: Article

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