SCOPUS 정보 검색 플랫폼

Pesticide Chemistry: Crop Protection, Public Health, Environmental Safety

Volumn , Issue , 2007, Pages 65-75

Target-Based Research: A Critical Review of Its Impact on Agrochemical Invention, Focusing on Examples Drawn from Fungicides

(2) Dunbar, Stuart J a Corran, Andrew J a

a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE (United Kingdom)

Author keywords

Agrochemical Invention; Assay design; Fungicides; High Throughput Technologies; Impact on agrochemical invention; in vitro screening; In Vitro Screening; in vitro to in vivo translation; New chemistry; Pesticide chemistry; Structure Based Design; Target Based Research

Indexed keywords

EID: 84891550848 PISSN: None EISSN: None Source Type: Book
DOI: 10.1002/9783527611249.ch7 Document Type: Chapter

Times cited : (4)

References (55)

1
- 0003494310
- Structure-Based Drug Design
- Marcel-Dekker, New York
- P. Veerpandian, Structure-Based Drug Design, Marcel-Dekker, New York, 1997.
- (1997)
- Veerpandian, P.¹

2
- 0031775318
- A. J. Corran, A. Renwick, S. J. Dunbar, Pestic. Sci., 1998, 54, 338-344.
- (1998) Pestic. Sci. , vol.54 , pp. 338-344
- Corran, A.J.¹ Renwick, A.² Dunbar, S.J.³

3
- 33746124645
- Chemistry of Crop Protection
- in, G. Voss, G. Ramos (Eds.), Wiley-VCH, Weinheim
- M. Pragnell in Chemistry of Crop Protection, G. Voss, G. Ramos (Eds.), Wiley-VCH, Weinheim, 2003.
- (2003)
- Pragnell, M.¹

4
- 0036873338
- K. Adachi, G. H. Nelson, K. A. Peoples, S. A. Frank, M. V. Montenegro-Chamorro, T. M. DeZwaan, L. Ramamurthy, J. R. Shuster, et al., Curr. Genet., 2002, 42, 123-127.
- (2002) Curr. Genet. , vol.42 , pp. 123-127
- Adachi, K.¹ Nelson, G.H.² Peoples, K.A.³ Frank, S.A.⁴ Montenegro-Chamorro, M.V.⁵ DeZwaan, T.M.⁶ Ramamurthy, L.⁷ Shuster, J.R.⁸

5
- 0035808973
- P. J. Balint-Kurti, G. D. May, A. C. Churchill, FEMS Microbiol. Lett., 2001, 195, 9-15.
- (2001) FEMS Microbiol. Lett. , vol.195 , pp. 9-15
- Balint-Kurti, P.J.¹ May, G.D.² Churchill, A.C.³

6
- 10744221744
- J. Kamper, Z. An, M. L. Farman, A. Budde, S. Taura, S. A. Leong, Mol. Genet. Genomics, 2004, 271, 103-110.
- (2004) Mol. Genet. Genomics , vol.271 , pp. 103-110
- Kamper, J.¹ An, Z.² Farman, M.L.³ Budde, A.⁴ Taura, S.⁵ Leong, S.A.⁶

7
- 0036775770
- S. Sogabe, M. Masubuchi, K. Sakata, T. A. Fukami, K. Morikami, Y. Shiratori, H. Ebiike, K. Kawasaki, et al., Chem. Biol., 2002, 9, 1119-1128.
- (2002) Chem. Biol. , vol.9 , pp. 1119-1128
- Sogabe, S.¹ Masubuchi, M.² Sakata, K.³ Fukami, T.A.⁴ Morikami, K.⁵ Shiratori, Y.⁶ Ebiike, H.⁷ Kawasaki, K.⁸

8
- 0035984270
- M. W. Walter, Nat. Prod. Rep., 2002, 19, 278-291.
- (2002) Nat. Prod. Rep. , vol.19 , pp. 278-291
- Walter, M.W.¹

9
- 84891512632
- in, J. Marshall Clark, H. Ohkawa (Eds.), American Chemical Society, Hawaii
- S. Gutteridge, S. O. Pember, L. Wu, Y. Tao, M. Walker in New Discoveries in Agrochemicals: ACS Symposium Series 892, J. Marshall Clark, H. Ohkawa (Eds.), American Chemical Society, Hawaii, 2005.
- (2005) New Discoveries in Agrochemicals: ACS Symposium Series 892
- Gutteridge, S.¹ Pember, S.O.² Wu, L.³ Tao, Y.⁴ Walker, M.⁵

10
- 0003757310
- in, H. Lyr (Ed.), Fischer, New York
- J. J. Steffens, D. A. Kleier in Modern Selective Fungicides, H. Lyr (Ed.), Fischer, New York, 1995.
- (1995) Modern Selective Fungicides
- Steffens, J.J.¹ Kleier, D.A.²

11
- 27144453780
- S. C. Smith, J. S. Delaney, M. P. Robinson, M. J. Rice, Comb. Chem. High Throughput Screen, 2005, 8, 577-587.
- (2005) Comb. Chem. High Throughput Screen , vol.8 , pp. 577-587
- Smith, S.C.¹ Delaney, J.S.² Robinson, M.P.³ Rice, M.J.⁴

12
- 27144554238
- K. Tietjen, M. Drewes, K. Stenzel, Comb. Chem. High Throughput Screen, 2005, 8, 589-594.
- (2005) Comb. Chem. High Throughput Screen , vol.8 , pp. 589-594
- Tietjen, K.¹ Drewes, M.² Stenzel, K.³

13
- 0034747024
- M. C. Costanzo, M. E. Crawford, J. E. Hirschman, J. E. Kranz, P. Olsen, L. S. Robertson, M. S. Skrzypek, B. R. Braun, et al., Nucl. Acids Res., 2001, 29, 75-79.
- (2001) Nucl. Acids Res. , vol.29 , pp. 75-79
- Costanzo, M.C.¹ Crawford, M.E.² Hirschman, J.E.³ Kranz, J.E.⁴ Olsen, P.⁵ Robertson, L.S.⁶ Skrzypek, M.S.⁷ Braun, B.R.⁸

14
- 0037249630
- S. Weng, Q. Dong, R. Balakrishnan, K. Christie, M. Costanzo, K. Dolinski, S. S. Dwight, S. Engel, et al., Nucl. Acids Res., 2003, 31, 216-218.
- (2003) Nucl. Acids Res. , vol.31 , pp. 216-218
- Weng, S.¹ Dong, Q.² Balakrishnan, R.³ Christie, K.⁴ Costanzo, M.⁵ Dolinski, K.⁶ Dwight, S.S.⁷ Engel, S.⁸

15
- 33748951972
- J. R. Xu, Y. L. Peng, M. B. Dickman, A. Sharon, Annu. Rev. Phytopathol., 2006, 44, 337-366.
- (2006) Annu. Rev. Phytopathol. , vol.44 , pp. 337-366
- Xu, J.R.¹ Peng, Y.L.² Dickman, M.B.³ Sharon, A.⁴

16
- 20244366844
- R. A. Dean, N. J. Talbot, D. J. Ebbole, M. L. Farman, T. K. Mitchell, M. J. Orbach, M. Thon, R. Kulkarni, et al., Nature, 2005, 434, 980-986.
- (2005) Nature , vol.434 , pp. 980-986
- Dean, R.A.¹ Talbot, N.J.² Ebbole, D.J.³ Farman, M.L.⁴ Mitchell, T.K.⁵ Orbach, M.J.⁶ Thon, M.⁷ Kulkarni, R.⁸

17
- 33645099889
- D. M. Soanes, N. J. Talbot, Mol. Plant Pathol., 2005, 7, 61-70.
- (2005) Mol. Plant Pathol. , vol.7 , pp. 61-70
- Soanes, D.M.¹ Talbot, N.J.²

18
- 33947405745
- M. Axelson-Fisk, P. Sunnerhagen, Topics Curr. Genet., 2006, 15, 1-15.
- (2006) Topics Curr. Genet. , vol.15 , pp. 1-15
- Axelson-Fisk, M.¹ Sunnerhagen, P.²

19
- 77957028825
- S. B. Goodwin, C. Waalwijk, G. H. J. Kema, Appl. Mycol. Biotechnol., 2004, 4, 315-330.
- (2004) Appl. Mycol. Biotechnol. , vol.4 , pp. 315-330
- Goodwin, S.B.¹ Waalwijk, C.² Kema, G.H.J.³

20
- 75749102762
- R. Beffa, Pflanzenschutz-Nachrichten Bayer, 2004, 57, 46-61.
- (2004) Pflanzenschutz-Nachrichten Bayer , vol.57 , pp. 46-61
- Beffa, R.¹

21
- 77957075240
- S. J. Assinder, Appl. Mycol. Biotechnol., 2004, 4, 137-160.
- (2004) Appl. Mycol. Biotechnol. , vol.4 , pp. 137-160
- Assinder, S.J.¹

22
- 85033489599
- J. E. Hamer, Advances in Fungal Biotechnology for Industry, Agriculture, and Medicine, J. S. Tkacz, L. Lange (Eds.), Kluwer Academic/Plenum Publishers, New York, 2004, 31-39.
- (2004) Advances in Fungal Biotechnology for Industry, Agriculture, and Medicine, J. S. Tkacz, L. Lange (Eds.), Kluwer Academic/Plenum Publishers, New York , pp. 31-39
- Hamer, J.E.¹

23
- 23144431938
- C. B. Michielse, P. J. J. Hooykaas, C. A. M. J. J. Hondel, A. F. J. Ram, Curr. Genet., 2005, 48, 1-17.
- (2005) Curr. Genet. , vol.48 , pp. 1-17
- Michielse, C.B.¹ Hooykaas, P.J.J.² Hondel, C.A.M.J.J.³ Ram, A.F.J.⁴

24
- 33644816388
- R. E. Cardoza, J. A. Vizcaino, M. R. Hermosa, S. Sousa, F. J. Gonzalez, A. Llobell, E. Monte, S. Gutierrez, Fungal Genet. Biol., 2006, 43, 164-178.
- (2006) Fungal Genet. Biol. , vol.43 , pp. 164-178
- Cardoza, R.E.¹ Vizcaino, J.A.² Hermosa, M.R.³ Sousa, S.⁴ Gonzalez, F.J.⁵ Llobell, A.⁶ Monte, E.⁷ Gutierrez, S.⁸

25
- 14644426575
- H. Nakayashiki, S. Hanada, B. Q. Nguyen, N. Kadotani, Y. Tosa, S. Mayama, Fungal Genet. Biol., 2005, 42, 275-283.
- (2005) Fungal Genet. Biol. , vol.42 , pp. 275-283
- Nakayashiki, H.¹ Hanada, S.² Nguyen, B.Q.³ Kadotani, N.⁴ Tosa, Y.⁵ Mayama, S.⁶

26
- 84891531615
- T. M. DeZwaan, K. D. Allen, M. M. Tanzer, K. Adachi, L. Ramamurthy, S. Mahanty, L. Hamer, Mycology Series, 2003, 18, 163-201.
- (2003) Mycology Series , vol.18 , pp. 163-201
- DeZwaan, T.M.¹ Allen, K.D.² Tanzer, M.M.³ Adachi, K.⁴ Ramamurthy, L.⁵ Mahanty, S.⁶ Hamer, L.⁷

27
- 84891531829
- R. Dickson, R. Lester, Biochim. Biophys. Acta, 1999, 1426, 349-357.
- (1999) Biochim. Biophys. Acta , vol.1426 , pp. 349-357
- Dickson, R.¹ Lester, R.²

28
- 0002304596
- Modern Fungicides and Antifungal Compounds
- In, H. Lyr, P. E. Russell, H. D. Sisler (Eds.), Intercept, Andover, UK
- B. C. Baldwin, J. M. Clough, C. R. A. Godfrey, J. R. Godwin, T. E. Wiggins. In Modern Fungicides and Antifungal Compounds, H. Lyr, P. E. Russell, H. D. Sisler (Eds.), Intercept, Andover, UK, 1996, 69-77.
- (1996) , pp. 69-77
- Baldwin, B.C.¹ Clough, J.M.² Godfrey, C.R.A.³ Godwin, J.R.⁴ Wiggins, T.E.⁵

29
- 0030970048
- M. M. Nagiec, E. E. Nagiec, J. A. Baltisberger, G. B. Wells, R. L. Lester, R. C. Dickson, J. Biol. Chem., 1997, 272, 9809-9817.
- (1997) J. Biol. Chem. , vol.272 , pp. 9809-9817
- Nagiec, M.M.¹ Nagiec, E.E.² Baltisberger, J.A.³ Wells, G.B.⁴ Lester, R.L.⁵ Dickson, R.C.⁶

30
- 0031453142
- S. M. Mandala, R. A. Thornton, M. Rosenbach, J. Milligan, M. Garcia-Calvo, H. G. Bull, M. B. Kurtz, J. Biol. Chem., 1997, 272, 32709-32714.
- (1997) J. Biol. Chem. , vol.272 , pp. 32709-32714
- Mandala, S.M.¹ Thornton, R.A.² Rosenbach, M.³ Milligan, J.⁴ Garcia-Calvo, M.⁵ Bull, H.G.⁶ Kurtz, M.B.⁷

31
- 17744410925
- S. M. Mandala, R. A. Thornton, J. Milligan, M. Rosenbach, M. Garcia-Calvo, H. G. Bull, G. Harris, G. K. Abruzzo, et al., J. Biol. Chem., 1998, 273, 14942-14949.
- (1998) J. Biol. Chem. , vol.273 , pp. 14942-14949
- Mandala, S.M.¹ Thornton, R.A.² Milligan, J.³ Rosenbach, M.⁴ Garcia-Calvo, M.⁵ Bull, H.G.⁶ Harris, G.⁷ Abruzzo, G.K.⁸

32
- 8844280061
- Y. Sugimoto, H. Sakoh, K. Yamada, Curr. Drug Targets Infect. Disord., 2004, 4, 311-322.
- (2004) Curr. Drug Targets Infect. Disord. , vol.4 , pp. 311-322
- Sugimoto, Y.¹ Sakoh, H.² Yamada, K.³

33
- 3142655272
- P. A. Aeed, A. E. Sperry, C. L. Young, M. M. Nagiec, A. P. Elhammer, W. Zhong, D. J. Murphy, N. H. Georgopapadakou, Biochemistry, 2004, 43, 8483-8493.
- (2004) Biochemistry , vol.43 , pp. 8483-8493
- Aeed, P.A.¹ Sperry, A.E.² Young, C.L.³ Nagiec, M.M.⁴ Elhammer, A.P.⁵ Zhong, W.⁶ Murphy, D.J.⁷ Georgopapadakou, N.H.⁸

34
- 0033406057
- W. Zhong, D. J. Murphy, N. H. Georgopapadakou, FEBS Lett., 1999, 463, 241-244.
- (1999) FEBS Lett. , vol.463 , pp. 241-244
- Zhong, W.¹ Murphy, D.J.² Georgopapadakou, N.H.³

35
- 0030720003
- G. Dixon, D. Scanlon, S. Cooper, P. Broad, J. Steroid Biochem. Mol. Biol., 1997, 62, 165-171.
- (1997) Biochem. Mol. Biol. , vol.62 , pp. 165-171
- Dixon, G.¹ Scanlon, D.² Cooper, S.³ Broad, P.⁴ Steroid, J.⁵

36
- 84879651440
- D. Debieu, J. Bach, M. Hugon, C. Malosse, P. Leroux, Pest. Manag. Sci., 2001, 57, 1060-1067.
- (2001) Pest. Manag. Sci. , vol.57 , pp. 1060-1067
- Debieu, D.¹ Bach, J.² Hugon, M.³ Malosse, C.⁴ Leroux, P.⁵

37
- 0003191839
- J. Rine, W. Hansen, E. Hardeman, R. W. Davis, Proc. Natl. Acad. Sci. USA, 1983, 80, 6750-6754.
- (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6750-6754
- Rine, J.¹ Hansen, W.² Hardeman, E.³ Davis, R.W.⁴

38
- 25444447107
- N. Fisher, B. Meunier, Pest. Manag. Sci., 2005, 61, 973-978.
- (2005) Pest. Manag. Sci. , vol.61 , pp. 973-978
- Fisher, N.¹ Meunier, B.²

39
- 0036672590
- J. M. Evans, P. G. Zaworski, C. N. Parker, J. Biomol. Screen., 2002, 7, 359-366.
- (2002) J. Biomol. Screen. , vol.7 , pp. 359-366
- Evans, J.M.¹ Zaworski, P.G.² Parker, C.N.³

40
- 0029073390
- D. J. Frost, K. D. Brandt, D. Cugier, R. Goldman, J. Antibiot. (Tokyo), 1995, 48, 306-310.
- (1995) J. Antibiot. (Tokyo) , vol.48 , pp. 306-310
- Frost, D.J.¹ Brandt, K.D.² Cugier, D.³ Goldman, R.⁴

41
- 0032524623
- J. K. Lodge, E. Jackson-Machelski, M. Higgins, C. A. McWherter, J. A. Sikorski, B. Devadas, J. I. Gordon, J. Biol. Chem., 1998, 273, 12482-12491.
- (1998) J. Biol. Chem. , vol.273 , pp. 12482-12491
- Lodge, J.K.¹ Jackson-Machelski, E.² Higgins, M.³ McWherter, C.A.⁴ Sikorski, J.A.⁵ Devadas, B.⁶ Gordon, J.I.⁷

42
- 17344386481
- H. Ebiike, M. Masubuchi, P. Liu, K. Kawasaki, K. Morikami, S. Sogabe, M. Hayase, T. Fujii, et al., Bioorg. Med. Chem. Lett., 2002, 12, 607-610.
- (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 607-610
- Ebiike, H.¹ Masubuchi, M.² Liu, P.³ Kawasaki, K.⁴ Morikami, K.⁵ Sogabe, S.⁶ Hayase, M.⁷ Fujii, T.⁸

43
- 0035939423
- M. Masubuchi, K. Kawasaki, H. Ebiike, Y. Ikeda, S. Tsujii, S. Sogabe, T. Fujii, K. Sakata, et al., Bioorg. Med. Chem. Lett., 2001, 11, 1833-1837.
- (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 1833-1837
- Masubuchi, M.¹ Kawasaki, K.² Ebiike, H.³ Ikeda, Y.⁴ Tsujii, S.⁵ Sogabe, S.⁶ Fujii, T.⁷ Sakata, K.⁸

44
- 17944387642
- K. Kawasaki, M. Masubuchi, K. Morikami, S. Sogabe, T. Aoyama, H. Ebiike, S. Niizuma, M. Hayase, et al., Bioorg. Med. Chem. Lett., 2003, 13, 87-91.
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 87-91
- Kawasaki, K.¹ Masubuchi, M.² Morikami, K.³ Sogabe, S.⁴ Aoyama, T.⁵ Ebiike, H.⁶ Niizuma, S.⁷ Hayase, M.⁸

45
- 0031889926
- S. A. Weston, R. Camble, J. Colls, G. Rosenbrock, I. Taylor, M. Egerton, A. D. Tucker, A. Tunnicliffe, et al., Nat. Struct. Biol., 1998, 5, 213-221.
- (1998) Nat. Struct. Biol. , vol.5 , pp. 213-221
- Weston, S.A.¹ Camble, R.² Colls, J.³ Rosenbrock, G.⁴ Taylor, I.⁵ Egerton, M.⁶ Tucker, A.D.⁷ Tunnicliffe, A.⁸

46
- 0036978283
- G. S. Basarab, D. B. Jordan, T. C. Gehret, R. S. Schwartz, Bioorg. Med. Chem., 2002, 10, 4143-4154.
- (2002) Bioorg. Med. Chem. , vol.10 , pp. 4143-4154
- Basarab, G.S.¹ Jordan, D.B.² Gehret, T.C.³ Schwartz, R.S.⁴

47
- 0032479524
- S. Iwata, J. W. Lee, K. Okada, J. K. Lee, M. Iwata, B. Rasmussen, T. A. Link, S. Ramaswamy, et al., Science, 1998, 281, 64-71.
- (1998) Science , vol.281 , pp. 64-71
- Iwata, S.¹ Lee, J.W.² Okada, K.³ Lee, J.K.⁴ Iwata, M.⁵ Rasmussen, B.⁶ Link, T.A.⁷ Ramaswamy, S.⁸

48
- 0032318375
- C. A. Yu, D. Xia, H. Kim, J. Deisenhofer, L. Zhang, A. M. Kachurin, L. Yu, Biochim. Biophys. Acta, 1998, 1365, 151-158.
- (1998) Biochim. Biophys. Acta , vol.1365 , pp. 151-158
- Yu, C.A.¹ Xia, D.² Kim, H.³ Deisenhofer, J.⁴ Zhang, L.⁵ Kachurin, A.M.⁶ Yu, L.⁷

49
- 0032759127
- C. A. Yu, H. Tian, L. Zhang, K. P. Deng, S. K. Shenoy, L. Yu, D. Xia, H. Kim, et al., J. Bioenerg. Biomembr., 1999, 31, 191-199.
- (1999) J. Bioenerg. Biomembr. , vol.31 , pp. 191-199
- Yu, C.A.¹ Tian, H.² Zhang, L.³ Deng, K.P.⁴ Shenoy, S.K.⁵ Yu, L.⁶ Xia, D.⁷ Kim, H.⁸

50
- 21244503033
- F. Sun, X. Huo, Y. Zhai, A. Wang, J. Xu, D. Su, M. Bartlam, Z. Rao, Cell, 2005, 121, 1043-1057
- (2005) Cell , vol.121 , pp. 1043-1057
- Sun, F.¹ Huo, X.² Zhai, Y.³ Wang, A.⁴ Xu, J.⁵ Su, D.⁶ Bartlam, M.⁷ Rao, Z.⁸

51
- 33646343221
- R. Horsefield, V. Yankovskaya, G. Sexton, W. Whittingham, K. Shiomi, S. Omura, B. Byrne, G. Cecchini, et al., J. Biol. Chem., 2006, 281, 7309-7316.
- (2006) J. Biol. Chem. , vol.281 , pp. 7309-7316
- Horsefield, R.¹ Yankovskaya, V.² Sexton, G.³ Whittingham, W.⁴ Shiomi, K.⁵ Omura, S.⁶ Byrne, B.⁷ Cecchini, G.⁸

52
- 33644874806
- U. Güldener, G. Mannhaupt, M. Munsterkötter, D. Haase, M. Oesterheld, V. Stümpflen, H. W. Mewes, G. Adam, Nucl. Acids Res., 2006, 34, D456-458.
- (2006) Nucl. Acids Res. , vol.34
- Güldener, U.¹ Mannhaupt, G.² Munsterkötter, M.³ Haase, D.⁴ Oesterheld, M.⁵ Stümpflen, V.⁶ Mewes, H.W.⁷ Adam, G.⁸

53
- 33644877905
- J. E. Hirschman, R. Balakrishnan, K. R. Christie, M. C. Costanzo, S. S. Dwight, S. R. Engel, D. G. Fisk, E. L. Hong, et al., Nucl. Acids Res., 2006, 34, D442-445.
- (2006) Nucl. Acids Res. , vol.34
- Hirschman, J.E.¹ Balakrishnan, R.² Christie, K.R.³ Costanzo, M.C.⁴ Dwight, S.S.⁵ Engel, S.R.⁶ Fisk, D.G.⁷ Hong, E.L.⁸

54
- 33645116839
- R. Mustacchi, S. Hohmann, J. Nielsen, Yeast, 2006, 23, 227-238.
- (2006) Yeast , vol.23 , pp. 227-238
- Mustacchi, R.¹ Hohmann, S.² Nielsen, J.³

55
- 5044226336
- E. C. Butcher, E. L. Berg, E. J. Kunkel, Nat. Biotech., 2004, 22, 1253-1259.
- (2004) Nat. Biotech. , vol.22 , pp. 1253-1259
- Butcher, E.C.¹ Berg, E.L.² Kunkel, E.J.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.