Crystal structures of Candida albicans N-myristoyltransferase with two distinct inhibitors

Chemistry and Biology

Volumn 9, Issue 10, 2002, Pages 1119-1128

  Sogabe, Satoshi ^a   Masubuchi, Miyako ^a   Sakata, Kiyoaki ^a   Fukami, Takaaki A ^a   Morikami, Kenji ^a   Shiratori, Yasuhiko ^a   Ebiike, Hirosato ^a   Kawasaki, Kenichi ^a   Aoki, Yuko ^a   Shimma, Nobuo ^a   D'Arcy, Allan ^b   Winkler, Fritz K ^b   Banner, David W ^b   Ohtsuka, Tatsuo ^a  

^a NIPPON ROCHE RESEARCH CENTER   (Japan)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; AMINO ACID; ENZYME INHIBITOR; GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE; IMIDAZOLE DERIVATIVE; OLIGOPEPTIDE; PROTEIN N MYRISTOYLTRANSFERASE; SC 58272;

ARTICLE; BINDING SITE; CANDIDA ALBICANS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ACYLTRANSFERASES; AMINO ACIDS; BINDING SITES; CANDIDA ALBICANS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; IMIDAZOLES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

CANDIDA; CANDIDA ALBICANS; EUKARYOTA;

EID: 0036775770     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00240-5     Document Type: Article

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