-
1
-
-
84870209800
-
Rho family GTPases
-
Hall A.Rho family GTPases.Biochem Soc Trans. 2012;40 (6): 1378-82.
-
(2012)
Biochem Soc Trans
, vol.40
, Issue.6
, pp. 1378-1382
-
-
Hall, A.1
-
2
-
-
34250737379
-
SnapShot: Rho family GTPases
-
Vega FM,Ridley AJ.SnapShot: Rho family GTPases.Cell. 2007 1430;129 (7):.
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1430
-
-
Vega, F.M.1
Ridley, A.J.2
-
4
-
-
44449178868
-
Rho GTPases in cancer cell biology
-
Vega FM,Ridley AJ.Rho GTPases in cancer cell biology.FEBS Lett. 2008;582 (14): 2093-101.
-
(2008)
FEBS Lett
, vol.582
, Issue.14
, pp. 2093-2101
-
-
Vega, F.M.1
Ridley, A.J.2
-
5
-
-
36348966706
-
Rho GTPases: functions and association with cancer
-
Ellenbroek SI,Collard JG.Rho GTPases: functions and association with cancer.Clin Exp Metastasis. 2007;24 (8): 657-72.
-
(2007)
Clin Exp Metastasis
, vol.24
, Issue.8
, pp. 657-672
-
-
Ellenbroek, S.I.1
Collard, J.G.2
-
6
-
-
13444252631
-
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
-
Rossman KL,Der CJ,Sondek J.GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.Nat Rev Mol Cell Biol. 2005;6 (2): 167-80.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.2
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
7
-
-
0033615978
-
Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis
-
Tatsumoto T,Xie X,Blumenthal R,Okamoto I,Miki T.Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis.J Cell Biol. 1999;147 (5): 921-8.
-
(1999)
J Cell Biol
, vol.147
, Issue.5
, pp. 921-928
-
-
Tatsumoto, T.1
Xie, X.2
Blumenthal, R.3
Okamoto, I.4
Miki, T.5
-
8
-
-
10744225152
-
Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation
-
Saito S,Liu XF,Kamijo K, et al.Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation.J Biol Chem. 2004;279 (8): 7169-79.
-
(2004)
J Biol Chem
, vol.279
, Issue.8
, pp. 7169-7179
-
-
Saito, S.1
Liu, X.F.2
Kamijo, K.3
-
9
-
-
3242702211
-
Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity
-
Liu XF,Ishida H,Raziuddin R,Miki T.Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity.Mol Cell Biol. 2004;24 (15): 6665-75.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.15
, pp. 6665-6675
-
-
Liu, X.F.1
Ishida, H.2
Raziuddin, R.3
Miki, T.4
-
10
-
-
0034625353
-
Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation
-
Kimura K,Tsuji T,Takada Y,Miki T,Narumiya S.Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation.J Biol Chem. 2000;275 (23): 17233-6.
-
(2000)
J Biol Chem
, vol.275
, Issue.23
, pp. 17233-17236
-
-
Kimura, K.1
Tsuji, T.2
Takada, Y.3
Miki, T.4
Narumiya, S.5
-
11
-
-
38749123941
-
Novel functions of Ect2 in polar lamellipodia formation and polarity maintenance during "contractile ring-independent" cytokinesis in adherent cells
-
Kanada M,Nagasaki A,Uyeda TQ.Novel functions of Ect2 in polar lamellipodia formation and polarity maintenance during "contractile ring-independent" cytokinesis in adherent cells.Mol Biol Cell. 2008;19 (1): 8-16.
-
(2008)
Mol Biol Cell
, vol.19
, Issue.1
, pp. 8-16
-
-
Kanada, M.1
Nagasaki, A.2
Uyeda, T.Q.3
-
12
-
-
77955299128
-
The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer
-
Fields AP,Justilien V.The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer.Adv Enzyme Regul. 2009;50 (1): 190-200.
-
(2009)
Adv Enzyme Regul
, vol.50
, Issue.1
, pp. 190-200
-
-
Fields, A.P.1
Justilien, V.2
-
13
-
-
84864115184
-
ECT2 and RASAL2 mediate mesenchymal-amoeboid transition in human astrocytoma cells
-
Weeks A,Okolowsky N,Golbourn B,Ivanchuk S,Smith C,Rutka JT.ECT2 and RASAL2 mediate mesenchymal-amoeboid transition in human astrocytoma cells.Am J Pathol. 2012;181 (2): 662-74.
-
(2012)
Am J Pathol
, vol.181
, Issue.2
, pp. 662-674
-
-
Weeks, A.1
Okolowsky, N.2
Golbourn, B.3
Ivanchuk, S.4
Smith, C.5
Rutka, J.T.6
-
14
-
-
84864011846
-
Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells
-
Fortin SP,Ennis MJ,Schumacher CA, et al.Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.Mol Cancer Res. 2012;10 (7): 958-68.
-
(2012)
Mol Cancer Res
, vol.10
, Issue.7
, pp. 958-968
-
-
Fortin, S.P.1
Ennis, M.J.2
Schumacher, C.A.3
-
15
-
-
70350074501
-
Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation
-
Justilien V,Fields AP.Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation.Oncogene. 2009;28 (41): 3597-607.
-
(2009)
Oncogene
, vol.28
, Issue.41
, pp. 3597-3607
-
-
Justilien, V.1
Fields, A.P.2
-
16
-
-
77951022275
-
The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3
-
Wang H,Linghu H,Wang J, et al.The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3.Tumour Biol. 2010;31 (1): 59-67.
-
(2010)
Tumour Biol
, vol.31
, Issue.1
, pp. 59-67
-
-
Wang, H.1
Linghu, H.2
Wang, J.3
-
17
-
-
15744404625
-
Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression
-
Bourguignon LY,Gilad E,Rothman K,Peyrollier K.Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.J Biol Chem. 2005;280 (12): 11961-72.
-
(2005)
J Biol Chem
, vol.280
, Issue.12
, pp. 11961-11972
-
-
Bourguignon, L.Y.1
Gilad, E.2
Rothman, K.3
Peyrollier, K.4
-
18
-
-
75749092545
-
RhoC expression level is correlated with the clinicopathological characteristics of ovarian cancer and the expression levels of ROCK-I, VEGF, and MMP9
-
Zhao Y,Zong ZH,Xu HM.RhoC expression level is correlated with the clinicopathological characteristics of ovarian cancer and the expression levels of ROCK-I, VEGF, and MMP9.Gynecol Oncol. 2009;116 (3): 563-71.
-
(2009)
Gynecol Oncol
, vol.116
, Issue.3
, pp. 563-571
-
-
Zhao, Y.1
Zong, Z.H.2
Xu, H.M.3
-
19
-
-
57349135304
-
Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer
-
Horiuchi A,Kikuchi N,Osada R, et al.Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer.Cancer Sci. 2008;99 (12): 2532-9.
-
(2008)
Cancer Sci
, vol.99
, Issue.12
, pp. 2532-2539
-
-
Horiuchi, A.1
Kikuchi, N.2
Osada, R.3
-
20
-
-
0028978027
-
Chromosomal localization of the human ECT2 proto-oncogene to 3q26.1→q26.2 by somatic cell analysis and fluorescence in situ hybridization
-
Takai S,Long JE,Yamada K,Miki T.Chromosomal localization of the human ECT2 proto-oncogene to 3q26.1→q26.2 by somatic cell analysis and fluorescence in situ hybridization.Genomics. 1995;27 (1): 220-2.
-
(1995)
Genomics
, vol.27
, Issue.1
, pp. 220-222
-
-
Takai, S.1
Long, J.E.2
Yamada, K.3
Miki, T.4
-
21
-
-
0034307169
-
An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer
-
Suzuki S,Moore DH,Ginzinger DG, et al.An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer.Cancer Res. 2000;60 (19): 5382-5.
-
(2000)
Cancer Res
, vol.60
, Issue.19
, pp. 5382-5385
-
-
Suzuki, S.1
Moore, D.H.2
Ginzinger, D.G.3
-
22
-
-
67949106468
-
High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors
-
Haverty PM,Hon LS,Kaminker JS,Chant J,Zhang Z.High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors.BMC Med Genomics. 2009;2:21.
-
(2009)
BMC Med Genomics
, vol.2
, pp. 21
-
-
Haverty, P.M.1
Hon, L.S.2
Kaminker, J.S.3
Chant, J.4
Zhang, Z.5
-
23
-
-
84866002291
-
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
-
Cerami E,Gao J,Dogrusoz U, et al.The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.Cancer Discov. 2012;2 (5): 401-4.
-
(2012)
Cancer Discov
, vol.2
, Issue.5
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
-
24
-
-
79959838081
-
Nature
-
Nature. 2011;474 (7353): 609-15.
-
(2011)
, vol.474
, Issue.7353
, pp. 609-615
-
-
-
25
-
-
0242526719
-
Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N-terminal cell cycle regulator-related domains
-
Saito S,Tatsumoto T,Lorenzi MV, et al.Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N-terminal cell cycle regulator-related domains.J Cell Biochem. 2003;90 (4): 819-36.
-
(2003)
J Cell Biochem
, vol.90
, Issue.4
, pp. 819-836
-
-
Saito, S.1
Tatsumoto, T.2
Lorenzi, M.V.3
-
26
-
-
33750361148
-
Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma
-
Rosen DG,Cai KQ,Luthra R,Liu J.Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma.Mod Pathol. 2006;19 (11): 1414-20.
-
(2006)
Mod Pathol
, vol.19
, Issue.11
, pp. 1414-1420
-
-
Rosen, D.G.1
Cai, K.Q.2
Luthra, R.3
Liu, J.4
-
27
-
-
33751575658
-
The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis
-
Rosen DG,Mercado-Uribe I,Yang G, et al.The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis.Cancer. 2006;107 (11): 2730-40.
-
(2006)
Cancer
, vol.107
, Issue.11
, pp. 2730-2740
-
-
Rosen, D.G.1
Mercado-Uribe, I.2
Yang, G.3
-
28
-
-
33646374432
-
Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma
-
Rosen DG,Yang G,Deavers MT, et al.Cyclin E expression is correlated with tumor progression and predicts a poor prognosis in patients with ovarian carcinoma.Cancer. 2006;106 (9): 1925-32.
-
(2006)
Cancer
, vol.106
, Issue.9
, pp. 1925-1932
-
-
Rosen, D.G.1
Yang, G.2
Deavers, M.T.3
-
29
-
-
80053299540
-
RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis
-
Stevens EV,Banet N,Onesto C, et al.RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis.Small GTPases. 2011;2 (4): 202-10.
-
(2011)
Small GTPases
, vol.2
, Issue.4
, pp. 202-210
-
-
Stevens, E.V.1
Banet, N.2
Onesto, C.3
-
30
-
-
0016318441
-
Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium
-
Freedman VH,Shin SI.Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.Cell. 1974;3 (4): 355-9.
-
(1974)
Cell
, vol.3
, Issue.4
, pp. 355-359
-
-
Freedman, V.H.1
Shin, S.I.2
-
31
-
-
77949902198
-
Cytokinesis and cancer: polo loves ROCK'n' Rho(A)
-
Li J,Wang J,Jiao H,Liao J,Xu X.Cytokinesis and cancer: polo loves ROCK'n' Rho(A).J Genet Genomics. 2010;37 (3): 159-72.
-
(2010)
J Genet Genomics
, vol.37
, Issue.3
, pp. 159-172
-
-
Li, J.1
Wang, J.2
Jiao, H.3
Liao, J.4
Xu, X.5
-
32
-
-
0142027035
-
The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences
-
Williams CL.The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences.Cell Signal. 2003;15 (12): 1071-80.
-
(2003)
Cell Signal
, vol.15
, Issue.12
, pp. 1071-1080
-
-
Williams, C.L.1
-
33
-
-
0038485593
-
Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1
-
Lanning CC,Ruiz-Velasco R,Williams CL.Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.J Biol Chem. 2003;278 (14): 12495-506.
-
(2003)
J Biol Chem
, vol.278
, Issue.14
, pp. 12495-12506
-
-
Lanning, C.C.1
Ruiz-Velasco, R.2
Williams, C.L.3
-
34
-
-
43149116339
-
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division
-
Michaelson D,Abidi W,Guardavaccaro D, et al.Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division.J Cell Biol. 2008;181 (3): 485-96.
-
(2008)
J Cell Biol
, vol.181
, Issue.3
, pp. 485-496
-
-
Michaelson, D.1
Abidi, W.2
Guardavaccaro, D.3
-
35
-
-
77951240109
-
Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype
-
Borikova AL,Dibble CF,Sciaky N, et al.Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype.J Biol Chem. 2010;285 (16): 11760-4.
-
(2010)
J Biol Chem
, vol.285
, Issue.16
, pp. 11760-11764
-
-
Borikova, A.L.1
Dibble, C.F.2
Sciaky, N.3
-
36
-
-
79952084024
-
The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals
-
Dubash AD,Guilluy C,Srougi MC,Boulter E,Burridge K,Garcia-Mata R.The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals.PLoS One. 2011;6 (2): e17380.
-
(2011)
PLoS One
, vol.6
, Issue.2
-
-
Dubash, A.D.1
Guilluy, C.2
Srougi, M.C.3
Boulter, E.4
Burridge, K.5
Garcia-Mata, R.6
-
37
-
-
31544476883
-
Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase
-
Hara T,Abe M,Inoue H, et al.Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase.Oncogene. 2006;25 (4): 566-78.
-
(2006)
Oncogene
, vol.25
, Issue.4
, pp. 566-578
-
-
Hara, T.1
Abe, M.2
Inoue, H.3
-
38
-
-
84861738385
-
Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus
-
Guilluy C,Dubash AD,Garcia-Mata R.Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus.Nat Protoc. 2011;6 (12): 2050-60.
-
(2011)
Nat Protoc
, vol.6
, Issue.12
, pp. 2050-2060
-
-
Guilluy, C.1
Dubash, A.D.2
Garcia-Mata, R.3
-
39
-
-
32144453465
-
Analysis of activated GAPs and GEFs in cell lysates
-
Garcia-Mata R,Wennerberg K,Arthur WT,Noren NK,Ellerbroek SM,Burridge K.Analysis of activated GAPs and GEFs in cell lysates.Methods Enzymol. 2006;406:425-37.
-
(2006)
Methods Enzymol
, vol.406
, pp. 425-437
-
-
Garcia-Mata, R.1
Wennerberg, K.2
Arthur, W.T.3
Noren, N.K.4
Ellerbroek, S.M.5
Burridge, K.6
-
40
-
-
0037044785
-
XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC
-
Arthur WT,Ellerbroek SM,Der CJ,Burridge K,Wennerberg K.XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.J Biol Chem. 2002;277 (45): 42964-72.
-
(2002)
J Biol Chem
, vol.277
, Issue.45
, pp. 42964-42972
-
-
Arthur, W.T.1
Ellerbroek, S.M.2
Der, C.J.3
Burridge, K.4
Wennerberg, K.5
-
41
-
-
3042801758
-
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis
-
Ellerbroek SM,Wennerberg K,Arthur WT, et al.SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.Mol Biol Cell. 2004;15 (7): 3309-19.
-
(2004)
Mol Biol Cell
, vol.15
, Issue.7
, pp. 3309-3319
-
-
Ellerbroek, S.M.1
Wennerberg, K.2
Arthur, W.T.3
-
42
-
-
0036091925
-
Ras signalling on the endoplasmic reticulum and the Golgi
-
Chiu VK,Bivona T,Hach A, et al.Ras signalling on the endoplasmic reticulum and the Golgi.Nat Cell Biol. 2002;4 (5): 343-50.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.5
, pp. 343-350
-
-
Chiu, V.K.1
Bivona, T.2
Hach, A.3
-
43
-
-
33744531777
-
Analysis of Ras activation in living cells with GFP-RBD
-
Bivona TG,Quatela S,Philips MR.Analysis of Ras activation in living cells with GFP-RBD.Methods Enzymol. 2006;407:128-43.
-
(2006)
Methods Enzymol
, vol.407
, pp. 128-143
-
-
Bivona, T.G.1
Quatela, S.2
Philips, M.R.3
-
44
-
-
0041488671
-
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
-
Bivona TG,Perez De Castro I,Ahearn IM, et al.Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1.Nature. 2003;424 (6949): 694-8.
-
(2003)
Nature
, vol.424
, Issue.6949
, pp. 694-698
-
-
Bivona, T.G.1
Perez de Castro, I.2
Ahearn, I.M.3
-
45
-
-
77956633945
-
Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src
-
Alan JK,Berzat AC,Dewar BJ,Graves LM,Cox AD.Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src.Mol Cell Biol. 2010;30 (17): 4324-38.
-
(2010)
Mol Cell Biol
, vol.30
, Issue.17
, pp. 4324-4338
-
-
Alan, J.K.1
Berzat, A.C.2
Dewar, B.J.3
Graves, L.M.4
Cox, A.D.5
-
46
-
-
33745599891
-
Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity
-
Chenette EJ,Mitin NY,Der CJ.Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity.Mol Biol Cell. 2006;17 (7): 3108-21.
-
(2006)
Mol Biol Cell
, vol.17
, Issue.7
, pp. 3108-3121
-
-
Chenette, E.J.1
Mitin, N.Y.2
Der, C.J.3
-
47
-
-
0032473569
-
A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways
-
Tapon N,Nagata K,Lamarche N,Hall A.A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways.EMBO J. 1998;17 (5): 1395-404.
-
(1998)
EMBO J
, vol.17
, Issue.5
, pp. 1395-1404
-
-
Tapon, N.1
Nagata, K.2
Lamarche, N.3
Hall, A.4
-
48
-
-
67651097663
-
PAK signaling in oncogenesis
-
Molli PR,Li DQ,Murray BW,Rayala SK,Kumar R.PAK signaling in oncogenesis.Oncogene. 2009;28 (28): 2545-55.
-
(2009)
Oncogene
, vol.28
, Issue.28
, pp. 2545-2555
-
-
Molli, P.R.1
Li, D.Q.2
Murray, B.W.3
Rayala, S.K.4
Kumar, R.5
-
49
-
-
11144226356
-
Models of the cooperative mechanism for Rho effector recognition: implications for RhoA-mediated effector activation
-
Blumenstein L,Ahmadian MR.Models of the cooperative mechanism for Rho effector recognition: implications for RhoA-mediated effector activation.J Biol Chem. 2004;279 (51): 53419-26.
-
(2004)
J Biol Chem
, vol.279
, Issue.51
, pp. 53419-53426
-
-
Blumenstein, L.1
Ahmadian, M.R.2
-
50
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley AJ,Hall A.The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors.Cell. 1992;70 (3): 389-99.
-
(1992)
Cell
, vol.70
, Issue.3
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
51
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley AJ,Paterson HF,Johnston CL,Diekmann D,Hall A.The small GTP-binding protein rac regulates growth factor-induced membrane ruffling.Cell. 1992;70 (3): 401-10.
-
(1992)
Cell
, vol.70
, Issue.3
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
52
-
-
0031260578
-
A novel Cdc42Hs mutant induces cellular transformation
-
Lin R,Bagrodia S,Cerione R,Manor D.A novel Cdc42Hs mutant induces cellular transformation.Curr Biol. 1997;7 (10): 794-7.
-
(1997)
Curr Biol
, vol.7
, Issue.10
, pp. 794-797
-
-
Lin, R.1
Bagrodia, S.2
Cerione, R.3
Manor, D.4
-
53
-
-
0344412931
-
Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling
-
Joyce PL,Cox AD.Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling.Cancer Res. 2003;63 (22): 7959-67.
-
(2003)
Cancer Res
, vol.63
, Issue.22
, pp. 7959-7967
-
-
Joyce, P.L.1
Cox, A.D.2
-
54
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon D,Roberts BL,Richardson WD,Smith AE.A short amino acid sequence able to specify nuclear location.Cell. 1984;39 (3 Pt 2): 499-509.
-
(1984)
Cell
, vol.39
, Issue.3 Pt
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
55
-
-
84864874567
-
Centralspindlin and alpha-catenin regulate Rho signalling at the epithelial zonula adherens
-
Ratheesh A,Gomez GA,Priya R, et al.Centralspindlin and alpha-catenin regulate Rho signalling at the epithelial zonula adherens.Nat Cell Biol. 2012;14 (8): 818-28.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.8
, pp. 818-828
-
-
Ratheesh, A.1
Gomez, G.A.2
Priya, R.3
-
56
-
-
78649760558
-
Epithelial cell transforming sequence 2 in human oral cancer
-
Iyoda M,Kasamatsu A,Ishigami T, et al.Epithelial cell transforming sequence 2 in human oral cancer.PLoS One. 2010;5 (11): e14082.
-
(2010)
PLoS One
, vol.5
, Issue.11
-
-
Iyoda, M.1
Kasamatsu, A.2
Ishigami, T.3
-
57
-
-
84868654087
-
The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration
-
Cook DR,Solski PA,Bultman SJ, et al.The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.Genes Cancer. 2011;2 (10): 932-42.
-
(2011)
Genes Cancer
, vol.2
, Issue.10
, pp. 932-942
-
-
Cook, D.R.1
Solski, P.A.2
Bultman, S.J.3
-
58
-
-
79953154962
-
The oncogenic activity of ECT2 is regulated through protein kinase C{iota} mediated phosphorylation
-
Justilien V,Jameison L,Der CJ,Rossman KL,Fields AP.The oncogenic activity of ECT2 is regulated through protein kinase C{iota} mediated phosphorylation.J Biol Chem. 2011;286 (10): 8149-57.
-
(2011)
J Biol Chem
, vol.286
, Issue.10
, pp. 8149-8157
-
-
Justilien, V.1
Jameison, L.2
Der, C.J.3
Rossman, K.L.4
Fields, A.P.5
-
59
-
-
58949091881
-
Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression
-
Hirata D,Yamabuki T,Miki D, et al.Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.Clin Cancer Res. 2009;15 (1): 256-66.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.1
, pp. 256-266
-
-
Hirata, D.1
Yamabuki, T.2
Miki, D.3
-
60
-
-
57149120776
-
The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma
-
Salhia B,Tran NL,Chan A, et al.The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.Am J Pathol. 2008;173 (6): 1828-38.
-
(2008)
Am J Pathol
, vol.173
, Issue.6
, pp. 1828-1838
-
-
Salhia, B.1
Tran, N.L.2
Chan, A.3
-
61
-
-
14044263688
-
The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis
-
Kim JE,Billadeau DD,Chen J.The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis.J Biol Chem. 2005;280 (7): 5733-9.
-
(2005)
J Biol Chem
, vol.280
, Issue.7
, pp. 5733-5739
-
-
Kim, J.E.1
Billadeau, D.D.2
Chen, J.3
-
62
-
-
78649835035
-
A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A
-
Lagana A,Dorn JF,De Rop V,Ladouceur AM,Maddox AS,Maddox PS.A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A.Nat Cell Biol. 2010;12 (12): 1186-93.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.12
, pp. 1186-1193
-
-
Lagana, A.1
Dorn, J.F.2
de Rop, V.3
Ladouceur, A.M.4
Maddox, A.S.5
Maddox, P.S.6
-
63
-
-
32544435801
-
Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA
-
Niiya F,Tatsumoto T,Lee KS,Miki T.Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA.Oncogene. 2006;25 (6): 827-37.
-
(2006)
Oncogene
, vol.25
, Issue.6
, pp. 827-837
-
-
Niiya, F.1
Tatsumoto, T.2
Lee, K.S.3
Miki, T.4
-
64
-
-
2942554939
-
Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation
-
Solski PA,Wilder RS,Rossman KL, et al.Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation.J Biol Chem. 2004;279 (24): 25226-33.
-
(2004)
J Biol Chem
, vol.279
, Issue.24
, pp. 25226-25233
-
-
Solski, P.A.1
Wilder, R.S.2
Rossman, K.L.3
-
65
-
-
13844252076
-
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
-
Oceguera-Yanez F,Kimura K,Yasuda S, et al.Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.J Cell Biol. 2005;168 (2): 221-32.
-
(2005)
J Cell Biol
, vol.168
, Issue.2
, pp. 221-232
-
-
Oceguera-Yanez, F.1
Kimura, K.2
Yasuda, S.3
-
66
-
-
63049085679
-
A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factors
-
Kawashima T,Bao YC,Minoshima Y, et al.A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factors.Mol Cell Biol. 2009;29 (7): 1796-813.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.7
, pp. 1796-1813
-
-
Kawashima, T.1
Bao, Y.C.2
Minoshima, Y.3
-
67
-
-
80052867878
-
Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma
-
Wang SM,Ooi LL,Hui KM.Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma.Clin Cancer Res. 2011;17 (18): 6040-51.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.18
, pp. 6040-6051
-
-
Wang, S.M.1
Ooi, L.L.2
Hui, K.M.3
-
68
-
-
80052277904
-
PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin
-
Tao J,Oladimeji P,Rider L,Diakonova M.PAK1-Nck regulates cyclin D1 promoter activity in response to prolactin.Mol Endocrinol. 2011;25 (9): 1565-78.
-
(2011)
Mol Endocrinol
, vol.25
, Issue.9
, pp. 1565-1578
-
-
Tao, J.1
Oladimeji, P.2
Rider, L.3
Diakonova, M.4
-
69
-
-
79952637148
-
The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation
-
Obrdlik A,Percipalle P.The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation.Nucleus. 2011;2 (1): 72-9.
-
(2011)
Nucleus
, vol.2
, Issue.1
, pp. 72-79
-
-
Obrdlik, A.1
Percipalle, P.2
-
70
-
-
0041438404
-
The Group 3 LIM domain protein paxillin potentiates androgen receptor transactivation in prostate cancer cell lines
-
Kasai M,Guerrero-Santoro J,Friedman R,Leman ES,Getzenberg RH,DeFranco DB.The Group 3 LIM domain protein paxillin potentiates androgen receptor transactivation in prostate cancer cell lines.Cancer Res. 2003;63 (16): 4927-35.
-
(2003)
Cancer Res
, vol.63
, Issue.16
, pp. 4927-4935
-
-
Kasai, M.1
Guerrero-Santoro, J.2
Friedman, R.3
Leman, E.S.4
Getzenberg, R.H.5
DeFranco, D.B.6
-
71
-
-
78649880786
-
p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients
-
Siu MK,Chan HY,Kong DS, et al.p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients.Proc Natl Acad Sci U S A. 2010;107 (43): 18622-7.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.43
, pp. 18622-18627
-
-
Siu, M.K.1
Chan, H.Y.2
Kong, D.S.3
-
72
-
-
77953465926
-
Differential expression and phosphorylation of Pak1 and Pak2 in ovarian cancer: effects on prognosis and cell invasion
-
Siu MK,Wong ES,Chan HY, et al.Differential expression and phosphorylation of Pak1 and Pak2 in ovarian cancer: effects on prognosis and cell invasion.Int J Cancer. 2010;127 (1): 21-31.
-
(2010)
Int J Cancer
, vol.127
, Issue.1
, pp. 21-31
-
-
Siu, M.K.1
Wong, E.S.2
Chan, H.Y.3
-
73
-
-
79960622503
-
Biogenesis and function of nuclear bodies
-
Mao YS,Zhang B,Spector DL.Biogenesis and function of nuclear bodies.Trends Genet. 2011;27 (8): 295-306.
-
(2011)
Trends Genet
, vol.27
, Issue.8
, pp. 295-306
-
-
Mao, Y.S.1
Zhang, B.2
Spector, D.L.3
-
74
-
-
84866525932
-
Charting the landscape of tandem BRCT domain-mediated protein interactions
-
Woods NT,Mesquita RD,Sweet M, et al.Charting the landscape of tandem BRCT domain-mediated protein interactions.Sci Signal. 2012;5 (242): rs6.
-
(2012)
Sci Signal
, vol.5
, Issue.242
-
-
Woods, N.T.1
Mesquita, R.D.2
Sweet, M.3
-
75
-
-
79952013333
-
The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage
-
Srougi MC,Burridge K.The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage.PLoS One. 2011;6 (2): e17108.
-
(2011)
PLoS One
, vol.6
, Issue.2
-
-
Srougi, M.C.1
Burridge, K.2
-
76
-
-
34748839538
-
Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor
-
Grabocka E,Wedegaertner PB.Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor.Mol Pharmacol. 2007;72 (4): 993-1002.
-
(2007)
Mol Pharmacol
, vol.72
, Issue.4
, pp. 993-1002
-
-
Grabocka, E.1
Wedegaertner, P.B.2
-
77
-
-
84856955553
-
A novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancer
-
Rao S,Lyons LS,Fahrenholtz CD, et al.A novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancer.Oncogene. 2012;31 (6): 716-27.
-
(2012)
Oncogene
, vol.31
, Issue.6
, pp. 716-727
-
-
Rao, S.1
Lyons, L.S.2
Fahrenholtz, C.D.3
-
78
-
-
33645516549
-
PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility
-
Fiordalisi JJ,Keller PJ,Cox AD.PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.Cancer Res. 2006;66 (6): 3153-61.
-
(2006)
Cancer Res
, vol.66
, Issue.6
, pp. 3153-3161
-
-
Fiordalisi, J.J.1
Keller, P.J.2
Cox, A.D.3
-
79
-
-
13444311711
-
Concentric zones of active RhoA and Cdc42 around single cell wounds
-
Benink HA,Bement WM.Concentric zones of active RhoA and Cdc42 around single cell wounds.J Cell Biol. 2005;168 (3): 429-39.
-
(2005)
J Cell Biol
, vol.168
, Issue.3
, pp. 429-439
-
-
Benink, H.A.1
Bement, W.M.2
-
80
-
-
39449083242
-
Adducin promotes micrometer-scale organization of beta2-spectrin in lateral membranes of bronchial epithelial cells
-
Abdi KM,Bennett V.Adducin promotes micrometer-scale organization of beta2-spectrin in lateral membranes of bronchial epithelial cells.Mol Biol Cell. 2008;19 (2): 536-45.
-
(2008)
Mol Biol Cell
, vol.19
, Issue.2
, pp. 536-545
-
-
Abdi, K.M.1
Bennett, V.2
-
81
-
-
59449093560
-
The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis
-
Brady DC,Alan JK,Madigan JP,Fanning AS,Cox AD.The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis.Mol Cell Biol. 2009;29 (4): 1035-49.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.4
, pp. 1035-1049
-
-
Brady, D.C.1
Alan, J.K.2
Madigan, J.P.3
Fanning, A.S.4
Cox, A.D.5
-
82
-
-
45549103808
-
Tools to study the function of the Ras-related, estrogen-regulated growth inhibitor in breast cancer
-
Hanker AB,Morita S,Repasky GA,Ross DT,Seitz RS,Der CJ.Tools to study the function of the Ras-related, estrogen-regulated growth inhibitor in breast cancer.Methods Enzymol. 2008;439:53-72.
-
(2008)
Methods Enzymol
, vol.439
, pp. 53-72
-
-
Hanker, A.B.1
Morita, S.2
Repasky, G.A.3
Ross, D.T.4
Seitz, R.S.5
Der, C.J.6
|