The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Srougi, Melissa C ^a   Burridge, Keith ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL CELL TRANSFORMING SEQUENCE 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYDROGEN PEROXIDE; NEUROEPITHELIAL TRANSFORMING PROTEIN 1; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ECT2 PROTEIN, HUMAN; NET1 PROTEIN, HUMAN; ONCOPROTEIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENOTOXICITY; HUMAN; HUMAN CELL; IONIZING RADIATION; LOSS OF FUNCTION MUTATION; PREDICTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; UTERINE CERVIX CANCER; BREAST TUMOR; CARCINOMA; CELL DEATH; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENETICS; HELA CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE;

BREAST NEOPLASMS; CARCINOMA; CELL DEATH; CELL LINE, TRANSFORMED; DNA DAMAGE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS; RHOB GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 79952013333     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017108     Document Type: Article

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