메뉴 건너뛰기




Volumn 19, Issue 11, 2006, Pages 1414-1420

Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma

Author keywords

hMLH1; hMSH2; Immunohistochemistry; Microsatellite instability; Ovarian carcinoma; Tissue microarrays

Indexed keywords

CD56 ANTIGEN; NERVE CELL ADHESION MOLECULE; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN MLH1; PROTEIN MSH2; RNA BINDING PROTEIN EWS; TRANSCRIPTION FACTOR FLI 1; UNCLASSIFIED DRUG;

EID: 33750361148     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800672     Document Type: Article
Times cited : (47)

References (33)
  • 1
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993;363:558-561.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3
  • 2
    • 24144493178 scopus 로고    scopus 로고
    • Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome
    • Baudhuin LM, Burgart LJ, Leontovich O, et al. Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome. Fam Cancer 2005;4:255-265.
    • (2005) Fam Cancer , vol.4 , pp. 255-265
    • Baudhuin, L.M.1    Burgart, L.J.2    Leontovich, O.3
  • 3
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-1038.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3
  • 4
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-1225.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papadopoulos, N.3
  • 5
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
    • Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994;368:258-261.
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1    Baker, S.M.2    Morrison, P.T.3
  • 6
    • 0027933070 scopus 로고
    • Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
    • Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
    • (1994) Nature , vol.371 , pp. 75-80
    • Nicolaides, N.C.1    Papadopoulos, N.2    Liu, B.3
  • 8
    • 16944361874 scopus 로고    scopus 로고
    • Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas
    • Yin J, Kong D, Wang S, et al. Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. Hum Mutat 1997;10:474-478.
    • (1997) Hum Mutat , vol.10 , pp. 474-478
    • Yin, J.1    Kong, D.2    Wang, S.3
  • 9
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel H, Frankel WL, Martin E, et al. Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N Engl J Med 2005;352:1851-1860.
    • (2005) N Engl J Med , vol.352 , pp. 1851-1860
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 10
    • 0028966917 scopus 로고
    • Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary nonpolyposis colorectal cancer (HNPCC)
    • Han HJ, Maruyama M, Baba S, et al. Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary nonpolyposis colorectal cancer (HNPCC). Hum Mol Genet 1995;4:237-242.
    • (1995) Hum Mol Genet , vol.4 , pp. 237-242
    • Han, H.J.1    Maruyama, M.2    Baba, S.3
  • 11
    • 0028106776 scopus 로고
    • HMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds
    • Liu B, Parsons RE, Hamilton SR, et al. hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. Cancer Res 1994;54:4590-4594.
    • (1994) Cancer Res , vol.54 , pp. 4590-4594
    • Liu, B.1    Parsons, R.E.2    Hamilton, S.R.3
  • 12
    • 0027136828 scopus 로고
    • Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
    • Lothe RA, Peltomaki P, Meling GI, et al. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 1993;53:5849-5852.
    • (1993) Cancer Res , vol.53 , pp. 5849-5852
    • Lothe, R.A.1    Peltomaki, P.2    Meling, G.I.3
  • 13
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-5257.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3
  • 14
    • 0032968046 scopus 로고    scopus 로고
    • Molecular genetics of ovarian carcinomas
    • Diebold J. Molecular genetics of ovarian carcinomas. Histol Histopathol 1999;14:269-277.
    • (1999) Histol Histopathol , vol.14 , pp. 269-277
    • Diebold, J.1
  • 15
    • 0029831117 scopus 로고    scopus 로고
    • Microsatellite instability differences between familial and sporadic ovarian cancers
    • Arzimanoglou II, Lallas T, Osborne M, et al. Microsatellite instability differences between familial and sporadic ovarian cancers. Carcinogenesis 1996;17:1799-1804.
    • (1996) Carcinogenesis , vol.17 , pp. 1799-1804
    • Arzimanoglou, I.I.1    Lallas, T.2    Osborne, M.3
  • 16
    • 0029597808 scopus 로고
    • Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer
    • Fujita M, Enomoto T, Yoshino K, et al. Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancer. Int J Cancer 1995;64:361-366.
    • (1995) Int J Cancer , vol.64 , pp. 361-366
    • Fujita, M.1    Enomoto, T.2    Yoshino, K.3
  • 17
    • 0029112453 scopus 로고
    • Microsatellite instability in ovarian neoplasms
    • King BL, Carcangiu ML, Carter D, et al. Microsatellite instability in ovarian neoplasms. Br J Cancer 1995;72:376-382.
    • (1995) Br J Cancer , vol.72 , pp. 376-382
    • King, B.L.1    Carcangiu, M.L.2    Carter, D.3
  • 18
    • 0032789079 scopus 로고    scopus 로고
    • Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair
    • Cawkwell L, Gray S, Murgatroyd H, et al. Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut 1999;45:409-415.
    • (1999) Gut , vol.45 , pp. 409-415
    • Cawkwell, L.1    Gray, S.2    Murgatroyd, H.3
  • 19
    • 0032852979 scopus 로고    scopus 로고
    • Immunohistochemistry for hMLH1 and hMSH2: A practical test for DNA mismatch repair-deficient tumors
    • Marcus VA, Madlensky L, Gryfe R, et al. Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors. Am J Surg Pathol 1999;23:1248-1255.
    • (1999) Am J Surg Pathol , vol.23 , pp. 1248-1255
    • Marcus, V.A.1    Madlensky, L.2    Gryfe, R.3
  • 20
    • 0033962257 scopus 로고    scopus 로고
    • Extensive molecular screening for hereditary nonpolyposis colorectal cancer
    • Dieumegard B, Grandjouan S, Sabourin JC, et al. Extensive molecular screening for hereditary nonpolyposis colorectal cancer. Br J Cancer 2000;82:871-880.
    • (2000) Br J Cancer , vol.82 , pp. 871-880
    • Dieumegard, B.1    Grandjouan, S.2    Sabourin, J.C.3
  • 21
    • 0033971331 scopus 로고    scopus 로고
    • Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancer
    • Debniak T, Kurzawski G, Gorski B, et al. Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancer. Eur J Cancer 2000;36:49-54.
    • (2000) Eur J Cancer , vol.36 , pp. 49-54
    • Debniak, T.1    Kurzawski, G.2    Gorski, B.3
  • 22
    • 0035161440 scopus 로고    scopus 로고
    • Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing
    • Terdiman JP, Gum Jr JR, Conrad PG, et al. Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing. Gastroenterology 2001;120:21-30.
    • (2001) Gastroenterology , vol.120 , pp. 21-30
    • Terdiman, J.P.1    Gum Jr., J.R.2    Conrad, P.G.3
  • 23
    • 0033846517 scopus 로고    scopus 로고
    • Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype
    • Chaves P, Cruz C, Lage P, et al. Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype. J Pathol 2000;191:355-360.
    • (2000) J Pathol , vol.191 , pp. 355-360
    • Chaves, P.1    Cruz, C.2    Lage, P.3
  • 24
    • 0037083484 scopus 로고    scopus 로고
    • Immunohistochemistry vs microsatellite instability testing in phenotyping colorectal tumors
    • Lindor NM, Burgart LJ, Leontovich O, et al. Immunohistochemistry vs microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol 2002;20:1043-1048.
    • (2002) J Clin Oncol , vol.20 , pp. 1043-1048
    • Lindor, N.M.1    Burgart, L.J.2    Leontovich, O.3
  • 25
    • 3042672714 scopus 로고    scopus 로고
    • Validation of tissue microarray technology in ovarian carcinoma
    • Rosen DG, Huang X, Deavers MT, et al. Validation of tissue microarray technology in ovarian carcinoma. Mod Pathol 2004;17:790-797.
    • (2004) Mod Pathol , vol.17 , pp. 790-797
    • Rosen, D.G.1    Huang, X.2    Deavers, M.T.3
  • 26
    • 2442670288 scopus 로고    scopus 로고
    • Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma
    • Cai KQ, Albarracin C, Rosen D, et al. Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma. Hum Pathol 2004;35:552-559.
    • (2004) Hum Pathol , vol.35 , pp. 552-559
    • Cai, K.Q.1    Albarracin, C.2    Rosen, D.3
  • 27
    • 0035360815 scopus 로고    scopus 로고
    • Application of the National Cancer Institute international criteria for determination of microsatellite instability in ovarian cancer
    • Sood AK, Holmes R, Hendrix MJ, et al. Application of the National Cancer Institute international criteria for determination of microsatellite instability in ovarian cancer. Cancer Res 2001;61:4371-4374.
    • (2001) Cancer Res , vol.61 , pp. 4371-4374
    • Sood, A.K.1    Holmes, R.2    Hendrix, M.J.3
  • 28
    • 0037083628 scopus 로고    scopus 로고
    • Microsatellite instability phenotype of tumors: Genotyping or immunohistochemistry? The jury is still out
    • de La Chapelle A. Microsatellite instability phenotype of tumors: genotyping or immunohistochemistry? The jury is still out. J Clin Oncol 2002;20:897-899.
    • (2002) J Clin Oncol , vol.20 , pp. 897-899
    • De La Chapelle, A.1
  • 29
    • 16644379607 scopus 로고    scopus 로고
    • The role of hMSH3 and hMSH6 in ovarian endometrioid carcinoma and relationship with microsatellite instability phenotype
    • Albarracin CT, Silva EG, Malpica A, et al. The role of hMSH3 and hMSH6 in ovarian endometrioid carcinoma and relationship with microsatellite instability phenotype. Oncol Rep 2004;12:1217-1219.
    • (2004) Oncol Rep , vol.12 , pp. 1217-1219
    • Albarracin, C.T.1    Silva, E.G.2    Malpica, A.3
  • 30
    • 0030008911 scopus 로고    scopus 로고
    • Frequent microsatellite instability in epithelial borderline ovarian tumors
    • Tangir J, Loughridge NS, Berkowitz RS, et al. Frequent microsatellite instability in epithelial borderline ovarian tumors. Cancer Res 1996;56:2501-2505.
    • (1996) Cancer Res , vol.56 , pp. 2501-2505
    • Tangir, J.1    Loughridge, N.S.2    Berkowitz, R.S.3
  • 31
    • 0035575740 scopus 로고    scopus 로고
    • Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors
    • Gras E, Catasus L, Arguelles R, et al. Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors. Cancer 2001;92:2829-2836.
    • (2001) Cancer , vol.92 , pp. 2829-2836
    • Gras, E.1    Catasus, L.2    Arguelles, R.3
  • 32
    • 2442712044 scopus 로고    scopus 로고
    • Microsatellite instability and expression of hMLH1 and hMSH2 proteins in ovarian endometrioid cancer
    • Liu J, Albarracin CT, Chang KH, et al. Microsatellite instability and expression of hMLH1 and hMSH2 proteins in ovarian endometrioid cancer. Mod Pathol 2004;17:75-80.
    • (2004) Mod Pathol , vol.17 , pp. 75-80
    • Liu, J.1    Albarracin, C.T.2    Chang, K.H.3
  • 33
    • 0035144251 scopus 로고    scopus 로고
    • Immunohistochemical pattern of hMSH2/hMLH1 in familial and sporadic colorectal, gastric, endometrial and ovarian carcinomas with instability in microsatellite sequences
    • Chiaravalli AM, Furlan D, Facco C, et al. Immunohistochemical pattern of hMSH2/hMLH1 in familial and sporadic colorectal, gastric, endometrial and ovarian carcinomas with instability in microsatellite sequences. Virchows Arch 2001;438:39-48.
    • (2001) Virchows Arch , vol.438 , pp. 39-48
    • Chiaravalli, A.M.1    Furlan, D.2    Facco, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.