Lipoic acid analogs with enhanced pharmacological activity

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 1, 2014, Pages 505-512

  Kates, Steven A ^a   Casale, Ralph A ^a   Baguisi, Alexander ^a   Beeuwkes III, Reinier ^a  

^a Ischemix LLC   (United States)

Author keywords

Amino acids; Ischemia reperfusion; Lipoic acid; Polymerization; SAR studies

Indexed keywords

[1,2 DITHIOLANE 3 PENTANOYL] LEVO GLUTAMYL LEVO ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] 2 AMINOETHYL HYDROGEN SULFATE; N [1,2 DITHIOLANE 3 PENTANOYL] 2 AMINOETHYL PHOSPHONIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] 3 AMINOBENZENE; N [1,2 DITHIOLANE 3 PENTANOYL] 4 AMINOBENZOIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] BETA ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] DEXTRO BETA FLOURO ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] IMINODIACETIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO (4 CARBOXY) PHENYLALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO ALANINYL LEVO GLUTAMIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO BETA FLOURO ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO CYSTEIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO GLUTAMIC ACID; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO GLUTAMINYL LEVO GLYCINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO GLUTAMINYL LEVO TAURINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO GLUTAMYL LEVO ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO TYROSINE; N [1,2 DITHIOLANE 3 PENTANOYL] LEVO TYROSINYL LEVO ALANINE; N [1,2 DITHIOLANE 3 PENTANOYL] O PHOSPHORYL ETHANOLAMINE; N [1,2 DITHIOLANE 3 PENTANOYL] TAURINE; THIOCTIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NONHUMAN; POLYMERIZATION; RAT; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

AMINO ACIDS; ISCHEMIA-REPERFUSION; LIPOIC ACID; POLYMERIZATION; SAR STUDIES;

ANIMALS; DISEASE MODELS, ANIMAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCTIC ACID;

EID: 84891482981     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.10.057     Document Type: Article

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