Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation

European Journal of Pharmacology

Volumn 678, Issue 1-3, 2012, Pages 32-38

  He, Lan ^a   Liu, Bin ^a   Dai, Zhong ^c   Zhang, Hong Feng ^a   Zhang, Yi Shuai ^a   Luo, Xiu Ju ^a   Ma, Qi Lin ^b   Peng, Jun ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

4 HNE (4 hydroxy 2 nonenal); ALDH2 (aldehyde dehydrogenase 2); Alpha lipoic acid; Hypoxia reoxygenation; Ischemia reperfusion

Indexed keywords

4 HYDROXYNONENAL; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CREATINE KINASE; MALONALDEHYDE; PROTEIN KINASE C EPSILON; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART FUNCTION; HEART MUSCLE CELL; HEART PROTECTION; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION INJURY; UPREGULATION;

ALDEHYDE DEHYDROGENASE; ALDEHYDES; ANIMALS; APOPTOSIS; CASPASE 3; CELLS, CULTURED; CREATINE KINASE; DISEASE MODELS, ANIMAL; HEART; MALE; MALONDIALDEHYDE; MITOCHONDRIAL PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; THIOCTIC ACID;

EID: 84862781173     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.12.042     Document Type: Article

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