-
1
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn EH. 2000. Telomere states and cell fates. Nature 408:53-56. http://dx.doi.org/10.1038/35040500.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
2
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee HW, Blasco MA, Gottlieb GJ, Horner JW, II, Greider CW, DePinho RA. 1998. Essential role of mouse telomerase in highly proliferative organs. Nature 392:569-574. http://dx.doi.org/10.1038/33345.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner II, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
3
-
-
0024973811
-
A mutant with a defect in telomere elongation leads to senescence in yeast
-
Lundblad V, Szostak JW. 1989. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57:633-643. http://dx.doi.org/10.1016/0092-8674(89)90132-3.
-
(1989)
Cell
, vol.57
, pp. 633-643
-
-
Lundblad, V.1
Szostak, J.W.2
-
4
-
-
69949085736
-
Telomeres and disease
-
Lansdorp PM. 2009. Telomeres and disease. EMBOJ. 28:2532-2540. http://dx.doi.org/10.1038/emboj.2009.172.
-
(2009)
EMBOJ
, vol.28
, pp. 2532-2540
-
-
Lansdorp, P.M.1
-
5
-
-
70350031814
-
RPA- like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway
-
Miyake Y, Nakamura M, Nabetani A, Shimamura S, Tamura M, Yonehara S, Saito M, Ishikawa F. 2009. RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol. Cell 36:193-206. http://dx.doi.org/10.1016/j.molcel.2009.08.009.
-
(2009)
Mol. Cell.
, vol.36
, pp. 193-206
-
-
Miyake, Y.1
Nakamura, M.2
Nabetani, A.3
Shimamura, S.4
Tamura, M.5
Yonehara, S.6
Saito, M.7
Ishikawa, F.8
-
6
-
-
70350036241
-
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes
-
Surovtseva YV, Churikov D, Boltz KA, Song X, Lamb JC, Warrington R, Leehy K, Heacock M, Price CM, Shippen DE. 2009. Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes. Mol. Cell 36:207-218. http://dx.doi.org/10.1016/j.molcel.2009.09.017.
-
(2009)
Mol. Cell.
, vol.36
, pp. 207-218
-
-
Surovtseva, Y.V.1
Churikov, D.2
Boltz, K.A.3
Song, X.4
Lamb, J.C.5
Warrington, R.6
Leehy, K.7
Heacock, M.8
Price, C.M.9
Shippen, D.E.10
-
7
-
-
77649179766
-
Common variants near TERC are associated with mean telomere length
-
Codd V, Mangino M, van der Harst P, Braund PS, Kaiser M, Beveridge AJ, Rafelt S, Moore J, Nelson C, Soranzo N, Zhai G, Valdes AM, Blackburn H, Mateo Leach I, de Boer RA, Kimura M, Aviv A, Goodall AH, Ouwehand W, van Veldhuisen DJ, van Gilst WH, Navis G, Burton PR, Tobin MD, Hall AS, Thompson JR, Spector T, Samani NJ. 2010. Common variants near TERC are associated with mean telomere length. Nat. Genet. 42:197-199. http://dx.doi.org/10.1038/ng.532.
-
(2010)
Nat. Genet.
, vol.42
, pp. 197-199
-
-
Codd, V.1
Mangino, M.2
van der Harst, P.3
Braund, P.S.4
Kaiser, M.5
Beveridge, A.J.6
Rafelt, S.7
Moore, J.8
Nelson, C.9
Soranzo, N.10
Zhai, G.11
Valdes, A.M.12
Blackburn, H.13
Mateo Leach, I.14
de Boer, R.A.15
Kimura, M.16
Aviv, A.17
Goodall, A.H.18
Ouwehand, W.19
van Veldhuisen, D.J.20
van Gilst, W.H.21
Navis, G.22
Burton, P.R.23
Tobin, M.D.24
Hall, A.S.25
Thompson, J.R.26
Spector, T.27
Samani, N.J.28
more..
-
8
-
-
77952703980
-
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology
-
Levy D, Neuhausen SL, Hunt SC, Kimura M, Hwang SJ, Chen W, Bis JC, Fitzpatrick AL, Smith E, Johnson AD, Gardner JP, Srinivasan SR, Schork N, Rotter JI, Herbig U, Psaty BM, Sastrasinh M, Murray SS, Vasan RS, Province MA, Glazer NL, Lu X, Cao X, Kronmal R, Mangino M, Soranzo N, Spector TD, Berenson GS, Aviv A. 2010. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc. Natl. Acad. Sci. U. S. A. 107:9293-9298. http://dx.doi.org/10.1073/pnas.0911494107.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 9293-9298
-
-
Levy, D.1
Neuhausen, S.L.2
Hunt, S.C.3
Kimura, M.4
Hwang, S.J.5
Chen, W.6
Bis, J.C.7
Fitzpatrick, A.L.8
Smith, E.9
Johnson, A.D.10
Gardner, J.P.11
Srinivasan, S.R.12
Schork, N.13
Rotter, J.I.14
Herbig, U.15
Psaty, B.M.16
Sastrasinh, M.17
Murray, S.S.18
Vasan, R.S.19
Province, M.A.20
Glazer, N.L.21
Lu, X.22
Cao, X.23
Kronmal, R.24
Mangino, M.25
Soranzo, N.26
Spector, T.D.27
Berenson, G.S.28
Aviv, A.29
more..
-
9
-
-
84870333736
-
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans
-
Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, Fitzpatrick AL, Christiansen L, Petersen I, Elbers CC, Harris T, Chen W, Srinivasan SR, Kark JD, Benetos A, El Shamieh S, Visvikis-Siest S, Christensen K, Berenson GS, Valdes AM, Vinuela A, Garcia M, Arnett DK, Broeckel U, Province MA, Pankow JS, Kammerer C, Liu Y, Nalls M, TishkoffS, Thomas F, Ziv E, Psaty BM, Bis JC, Rotter JI, Taylor KD, Smith E, Schork NJ, Levy D, Aviv A. 2012. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum. Mol. Genet. 21:5385-5394. http://dx.doi.org/10.1093/hmg/dds382.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 5385-5394
-
-
Mangino, M.1
Hwang, S.J.2
Spector, T.D.3
Hunt, S.C.4
Kimura, M.5
Fitzpatrick, A.L.6
Christiansen, L.7
Petersen, I.8
Elbers, C.C.9
Harris, T.10
Chen, W.11
Srinivasan, S.R.12
Kark, J.D.13
Benetos, A.14
El Shamieh, S.15
Visvikis-Siest, S.16
Christensen, K.17
Berenson, G.S.18
Valdes, A.M.19
Vinuela, A.20
Garcia, M.21
Arnett, D.K.22
Broeckel, U.23
Province, M.A.24
Pankow, J.S.25
Kammerer, C.26
Liu, Y.27
Nalls, M.28
Tishkoff, S.29
Thomas, F.30
Ziv, E.31
Psaty, B.M.32
Bis, J.C.33
Rotter, J.I.34
Taylor, K.D.35
Smith, E.36
Schork, N.J.37
Levy, D.38
Aviv, A.39
more..
-
10
-
-
0027509950
-
Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase
-
Wellinger RJ, Wolf AJ, Zakian VA. 1993. Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell 72:51-60. http://dx.doi.org/10.1016/0092-8674(93)90049-V.
-
(1993)
Cell
, vol.72
, pp. 51-60
-
-
Wellinger, R.J.1
Wolf, A.J.2
Zakian, V.A.3
-
11
-
-
0030474816
-
Structure, function, and replication of Saccharomyces cerevisiae telomeres
-
Zakian VA. 1996. Structure, function, and replication of Saccharomyces cerevisiae telomeres. Annu. Rev. Genet. 30:141-172. http://dx.doi.org/10.1146/annurev.genet.30.1.141.
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 141-172
-
-
Zakian, V.A.1
-
12
-
-
2942532256
-
A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length
-
Askree SH, Yehuda T, Smolikov S, Gurevich R, Hawk J, Coker C, Krauskopf A, Kupiec M, McEachern MJ. 2004. A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc. Natl. Acad. Sci. U. S. A. 101:8658-8663. http://dx.doi.org/10.1073/pnas.0401263101.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 8658-8663
-
-
Askree, S.H.1
Yehuda, T.2
Smolikov, S.3
Gurevich, R.4
Hawk, J.5
Coker, C.6
Krauskopf, A.7
Kupiec, M.8
McEachern, M.J.9
-
13
-
-
33645793749
-
Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast
-
Gatbonton T, Imbesi M, Nelson M, Akey JM, Ruderfer DM, Kruglyak L, Simon JA, Bedalov A. 2006. Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet. 2:e35. http://dx.doi.org/10.1371/journal.pgen.0020035.
-
(2006)
PLoS Genet
, vol.2
-
-
Gatbonton, T.1
Imbesi, M.2
Nelson, M.3
Akey, J.M.4
Ruderfer, D.M.5
Kruglyak, L.6
Simon, J.A.7
Bedalov, A.8
-
14
-
-
0027212282
-
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
-
Weinert TA, Hartwell LH. 1993. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134:63-80.
-
(1993)
Genetics
, vol.134
, pp. 63-80
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
15
-
-
0028822203
-
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
-
Garvik B, Carson M, Hartwell L. 1995. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:6128-6138.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6128-6138
-
-
Garvik, B.1
Carson, M.2
Hartwell, L.3
-
16
-
-
5144219712
-
Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants
-
Zubko MK, Guillard S, Lydall D. 2004. Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics 168:103-115. http://dx.doi.org/10.1534/genetics.104.027904.
-
(2004)
Genetics
, vol.168
, pp. 103-115
-
-
Zubko, M.K.1
Guillard, S.2
Lydall, D.3
-
17
-
-
67649653968
-
Multiple pathways regulate 3= overhang generation at S. cerevisiae telomeres
-
Bonetti D, Martina M, Clerici M, Lucchini G, Longhese MP. 2009. Multiple pathways regulate 3= overhang generation at S. cerevisiae telomeres. Mol. Cell 35:70-81. http://dx.doi.org/10.1016/j.molcel.2009.05.015.
-
(2009)
Mol. Cell
, vol.35
, pp. 70-81
-
-
Bonetti, D.1
Martina, M.2
Clerici, M.3
Lucchini, G.4
Longhese, M.P.5
-
18
-
-
33750431337
-
Regulation of telomere elongation by the cyclin-dependent kinase CDK1
-
Frank CJ, Hyde M, Greider CW. 2006. Regulation of telomere elongation by the cyclin-dependent kinase CDK1. Mol. Cell 24:423-432. http://dx.doi.org/10.1016/j.molcel.2006.10.020.
-
(2006)
Mol. Cell.
, vol.24
, pp. 423-432
-
-
Frank, C.J.1
Hyde, M.2
Greider, C.W.3
-
19
-
-
33749059184
-
DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase
-
Vodenicharov MD, Wellinger RJ. 2006. DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase. Mol. Cell 24:127-137. http://dx.doi.org/10.1016/j.molcel.2006.07.035.
-
(2006)
Mol. Cell.
, vol.24
, pp. 127-137
-
-
Vodenicharov, M.D.1
Wellinger, R.J.2
-
20
-
-
0035282781
-
Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
-
Grandin N, Damon C, Charbonneau M. 2001. Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J. 20:1173-1183. http://dx.doi.org/10.1093/emboj/20.5.1173.
-
(2001)
EMBO J
, vol.20
, pp. 1173-1183
-
-
Grandin, N.1
Damon, C.2
Charbonneau, M.3
-
21
-
-
0031029001
-
Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
-
Grandin N, Reed SI, Charbonneau M. 1997. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 11:512-527. http://dx.doi.org/10.1101/gad.11.4.512.
-
(1997)
Genes Dev
, vol.11
, pp. 512-527
-
-
Grandin, N.1
Reed, S.I.2
Charbonneau, M.3
-
22
-
-
68149170958
-
Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation
-
Qian W, Wang J, Jin NN, Fu XH, Lin YC, Lin JJ, Zhou JQ. 2009. Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation. Cell Res. 19:849-863. http://dx.doi.org/10.1038/cr.2009.67.
-
(2009)
Cell Res
, vol.19
, pp. 849-863
-
-
Qian, W.1
Wang, J.2
Jin, N.N.3
Fu, X.H.4
Lin, Y.C.5
Lin, J.J.6
Zhou, J.Q.7
-
23
-
-
33847675342
-
RPA-like proteins mediate yeast telomere function
-
Gao H, Cervantes RB, Mandell EK, Otero JH, Lundblad V. 2007. RPA-like proteins mediate yeast telomere function. Nat. Struct. Mol. Biol. 14:208-214. http://dx.doi.org/10.1038/nsmb1205.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 208-214
-
-
Gao, H.1
Cervantes, R.B.2
Mandell, E.K.3
Otero, J.H.4
Lundblad, V.5
-
24
-
-
72849112077
-
Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres
-
Sun J, Yu EY, Yang Y, Confer LA, Sun SH, Wan K, Lue NF, Lei M. 2009. Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres. Genes Dev. 23: 2900-2914. http://dx.doi.org/10.1101/gad.1851909.
-
(2009)
Genes Dev
, vol.23
, pp. 2900-2914
-
-
Sun, J.1
Yu, E.Y.2
Yang, Y.3
Confer, L.A.4
Sun, S.H.5
Wan, K.6
Lue, N.F.7
Lei, M.8
-
26
-
-
0030455861
-
Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
-
Lendvay TS, Morris DK, Sah J, Balasubramanian B, Lundblad V. 1996. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics 144:1399-1412.
-
(1996)
Genetics
, vol.144
, pp. 1399-1412
-
-
Lendvay, T.S.1
Morris, D.K.2
Sah, J.3
Balasubramanian, B.4
Lundblad, V.5
-
27
-
-
0035115859
-
Cdc13 both positively and negatively regulates telomere replication
-
Chandra A, Hughes TR, Nugent CI, Lundblad V. 2001. Cdc13 both positively and negatively regulates telomere replication. Genes Dev. 15: 404-414. http://dx.doi.org/10.1101/gad.861001.
-
(2001)
Genes Dev
, vol.15
, pp. 404-414
-
-
Chandra, A.1
Hughes, T.R.2
Nugent, C.I.3
Lundblad, V.4
-
28
-
-
0035830494
-
Cdc13 delivers separate complexes to the telomere for end protection and replication
-
Pennock E, Buckley K, Lundblad V. 2001. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104:387-396. http://dx.doi.org/10.1016/S0092-8674(01)00226-4.
-
(2001)
Cell
, vol.104
, pp. 387-396
-
-
Pennock, E.1
Buckley, K.2
Lundblad, V.3
-
29
-
-
0029845892
-
Cdc13p: a singlestrand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
-
Nugent CI, Hughes TR, Lue NF, Lundblad V. 1996. Cdc13p: a singlestrand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 274:249-252. http://dx.doi.org/10.1126/science.274.5285.249.
-
(1996)
Science
, vol.274
, pp. 249-252
-
-
Nugent, C.I.1
Hughes, T.R.2
Lue, N.F.3
Lundblad, V.4
-
30
-
-
0033598944
-
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta
-
Diede SJ, Gottschling DE. 1999. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 99:723-733. http://dx.doi.org/10.1016/S0092-8674(00)81670-0.
-
(1999)
Cell
, vol.99
, pp. 723-733
-
-
Diede, S.J.1
Gottschling, D.E.2
-
31
-
-
0034175814
-
Cell cycle restriction of telomere elongation
-
Marcand S, Brevet V, Mann C, Gilson E. 2000. Cell cycle restriction of telomere elongation. Curr. Biol. 10:487-490. http://dx.doi.org/10.1016/S0960-9822(00)00450-4.
-
(2000)
Curr. Biol.
, vol.10
, pp. 487-490
-
-
Marcand, S.1
Brevet, V.2
Mann, C.3
Gilson, E.4
-
32
-
-
0347988057
-
RPA regulates telomerase action by providing Est1p access to chromosome ends
-
Schramke V, Luciano P, Brevet V, Guillot S, Corda Y, Longhese MP, Gilson E, Geli V. 2004. RPA regulates telomerase action by providing Est1p access to chromosome ends. Nat. Genet. 36:46-54. http://dx.doi.org/10.1038/ng1284.
-
(2004)
Nat. Genet.
, vol.36
, pp. 46-54
-
-
Schramke, V.1
Luciano, P.2
Brevet, V.3
Guillot, S.4
Corda, Y.5
Longhese, M.P.6
Gilson, E.7
Geli, V.8
-
33
-
-
0037047643
-
Est1p as a cell cycle-regulated activator of telomere-bound telomerase
-
Taggart AK, Teng SC, Zakian VA. 2002. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297:1023-1026. http://dx.doi.org/10.1126/science.1074968.
-
(2002)
Science
, vol.297
, pp. 1023-1026
-
-
Taggart, A.K.1
Teng, S.C.2
Zakian, V.A.3
-
34
-
-
0030460748
-
Cell cycle-regulated generation of singlestranded G-rich DNA in the absence of telomerase
-
Dionne I, Wellinger RJ. 1996. Cell cycle-regulated generation of singlestranded G-rich DNA in the absence of telomerase. Proc. Natl. Acad. Sci. U. S. A. 93:13902-13907. http://dx.doi.org/10.1073/pnas.93.24.13902.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 13902-13907
-
-
Dionne, I.1
Wellinger, R.J.2
-
35
-
-
0027298574
-
Origin activation and formation of single-strand TG1-3 tails occur sequentially in late S phase on a yeast linear plasmid
-
Wellinger RJ, Wolf AJ, Zakian VA. 1993. Origin activation and formation of single-strand TG1-3 tails occur sequentially in late S phase on a yeast linear plasmid. Mol. Cell. Biol. 13:4057-4065.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4057-4065
-
-
Wellinger, R.J.1
Wolf, A.J.2
Zakian, V.A.3
-
36
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu Z, Chung WH, Shim EY, Lee SE, Ira G. 2008. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134: 981-994. http://dx.doi.org/10.1016/j.cell.2008.08.037.
-
(2008)
Cell
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
-
37
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou EP, Symington LS. 2008. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455:770-774. http://dx.doi.org/10.1038/nature07312.
-
(2008)
Nature
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
38
-
-
84863622662
-
Telomeric 3= overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST
-
Wu P, Takai H, de Lange T. 2012. Telomeric 3= overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell 150:39-52. http://dx.doi.org/10.1016/j.cell.2012.05.026.
-
(2012)
Cell
, vol.150
, pp. 39-52
-
-
Wu, P.1
Takai, H.2
de Lange, T.3
-
39
-
-
58149094903
-
Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression
-
Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, Blackburn EH. 2009. Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. Cell 136:50-61. http://dx.doi.org/10.1016/j.cell.2008.11.027.
-
(2009)
Cell
, vol.136
, pp. 50-61
-
-
Li, S.1
Makovets, S.2
Matsuguchi, T.3
Blethrow, J.D.4
Shokat, K.M.5
Blackburn, E.H.6
-
40
-
-
34547499407
-
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases
-
Smolka MB, Albuquerque CP, Chen SH, Zhou H. 2007. Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proc. Natl. Acad. Sci. U. S. A. 104:10364-10369. http://dx.doi.org/10.1073/pnas.0701622104.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10364-10369
-
-
Smolka, M.B.1
Albuquerque, C.P.2
Chen, S.H.3
Zhou, H.4
-
41
-
-
67649853453
-
Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13
-
Tseng SF, Shen ZJ, Tsai HJ, Lin YH, Teng SC. 2009. Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13. Nucleic Acids Res. 37:3602-3611. http://dx.doi.org/10.1093/nar/gkp235.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 3602-3611
-
-
Tseng, S.F.1
Shen, Z.J.2
Tsai, H.J.3
Lin, Y.H.4
Teng, S.C.5
-
42
-
-
0003245690
-
mRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiae
-
Dahlseid JN, Lew-Smith J, Lelivelt MJ, Enomoto S, Ford A, Desruisseaux M, McClellan M, Lue N, Culbertson MR, Berman J. 2003. mRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiae. Eukaryot. Cell 2:134-142. http://dx.doi.org/10.1128/EC.2.1.134-142.2003.
-
(2003)
Eukaryot. Cell.
, vol.2
, pp. 134-142
-
-
Dahlseid, J.N.1
Lew-Smith, J.2
Lelivelt, M.J.3
Enomoto, S.4
Ford, A.5
Desruisseaux, M.6
McClellan, M.7
Lue, N.8
Culbertson, M.R.9
Berman, J.10
-
43
-
-
2442564703
-
Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation
-
Grossi S, Puglisi A, Dmitriev PV, Lopes M, Shore D. 2004. Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Genes Dev. 18:992-1006. http://dx.doi.org/10.1101/gad.300004.
-
(2004)
Genes Dev
, vol.18
, pp. 992-1006
-
-
Grossi, S.1
Puglisi, A.2
Dmitriev, P.V.3
Lopes, M.4
Shore, D.5
-
44
-
-
51049092483
-
Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
-
Puglisi A, Bianchi A, Lemmens L, Damay P, Shore D. 2008. Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition. EMBO J. 27:2328-2339. http://dx.doi.org/10.1038/emboj.2008.158.
-
(2008)
EMBO J
, vol.27
, pp. 2328-2339
-
-
Puglisi, A.1
Bianchi, A.2
Lemmens, L.3
Damay, P.4
Shore, D.5
-
45
-
-
67650337568
-
The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states
-
DeZwaan DC, Toogun OA, Echtenkamp FJ, Freeman BC. 2009. The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states. Nat. Struct. Mol. Biol. 16:711-716. http://dx.doi.org/10.1038/nsmb.1616.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 711-716
-
-
DeZwaan, D.C.1
Toogun, O.A.2
Echtenkamp, F.J.3
Freeman, B.C.4
-
46
-
-
84865263603
-
The human CST complex is a terminator of telomerase activity
-
Chen LY, Redon S, Lingner J. 2012. The human CST complex is a terminator of telomerase activity. Nature 488:540-544. http://dx.doi.org/10.1038/nature11269.
-
(2012)
Nature
, vol.488
, pp. 540-544
-
-
Chen, L.Y.1
Redon, S.2
Lingner, J.3
-
47
-
-
2042534735
-
Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states
-
Teixeira MT, Arneric M, Sperisen P, Lingner J. 2004. Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states. Cell 117:323-335. http://dx.doi.org/10.1016/S0092-8674(04)00334-4.
-
(2004)
Cell
, vol.117
, pp. 323-335
-
-
Teixeira, M.T.1
Arneric, M.2
Sperisen, P.3
Lingner, J.4
-
48
-
-
0034841844
-
The tandem affinity purification (TAP) method: a general procedure of protein complex purification
-
Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, Bragado-Nilsson E, Wilm M, Seraphin B. 2001. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24:218-229. http://dx.doi.org/10.1006/meth.2001.1183.
-
(2001)
Methods
, vol.24
, pp. 218-229
-
-
Puig, O.1
Caspary, F.2
Rigaut, G.3
Rutz, B.4
Bouveret, E.5
Bragado-Nilsson, E.6
Wilm, M.7
Seraphin, B.8
-
49
-
-
0242300176
-
Targets of the cyclin-dependent kinase Cdk1
-
Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO. 2003. Targets of the cyclin-dependent kinase Cdk1. Nature 425:859-864. http://dx.doi.org/10.1038/nature02062.
-
(2003)
Nature
, vol.425
, pp. 859-864
-
-
Ubersax, J.A.1
Woodbury, E.L.2
Quang, P.N.3
Paraz, M.4
Blethrow, J.D.5
Shah, K.6
Shokat, K.M.7
Morgan, D.O.8
-
50
-
-
0028004378
-
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1
-
Moretti P, Freeman K, Coodly L, Shore D. 1994. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8:2257-2269. http://dx.doi.org/10.1101/gad.8.19.2257.
-
(1994)
Genes Dev
, vol.8
, pp. 2257-2269
-
-
Moretti, P.1
Freeman, K.2
Coodly, L.3
Shore, D.4
-
51
-
-
0034699382
-
A chemical switch for inhibitor-sensitive alleles of any protein kinase
-
Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. 2000. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature 407:395-401. http://dx.doi.org/10.1038/35030148.
-
(2000)
Nature
, vol.407
, pp. 395-401
-
-
Bishop, A.C.1
Ubersax, J.A.2
Petsch, D.T.3
Matheos, D.P.4
Gray, N.S.5
Blethrow, J.6
Shimizu, E.7
Tsien, J.Z.8
Schultz, P.G.9
Rose, M.D.10
Wood, J.L.11
Morgan, D.O.12
Shokat, K.M.13
-
52
-
-
73349109843
-
Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain
-
Gelinas AD, Paschini M, Reyes FE, Heroux A, Batey RT, Lundblad V, Wuttke DS. 2009. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc. Natl. Acad. Sci. U. S. A. 106:19298-19303. http://dx.doi.org/10.1073/pnas.0909203106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 19298-19303
-
-
Gelinas, A.D.1
Paschini, M.2
Reyes, F.E.3
Heroux, A.4
Batey, R.T.5
Lundblad, V.6
Wuttke, D.S.7
-
53
-
-
3442896884
-
Replication protein A phosphorylation and the cellular response to DNA damage
-
Binz SK, Sheehan AM, Wold MS. 2004. Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair (Amst.) 3:1015-1024. http://dx.doi.org/10.1016/j.dnarep.2004.03.028.
-
(2004)
DNA Repair (Amst.).
, vol.3
, pp. 1015-1024
-
-
Binz, S.K.1
Sheehan, A.M.2
Wold, M.S.3
-
54
-
-
20444375871
-
DNA damage induced hyperphosphorylation of replication protein A, 1. Identification of novel sites of phosphorylation in response to DNA damage
-
Nuss JE, Patrick SM, Oakley GG, Alter GM, Robison JG, Dixon K, Turchi JJ. 2005. DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage. Biochemistry 44:8428-8437. http://dx.doi.org/10.1021/bi0480584.
-
(2005)
Biochemistry
, vol.44
, pp. 8428-8437
-
-
Nuss, J.E.1
Patrick, S.M.2
Oakley, G.G.3
Alter, G.M.4
Robison, J.G.5
Dixon, K.6
Turchi, J.J.7
-
55
-
-
37249080597
-
Sequential and synergistic modification of human RPA stimulates chromosomalDNArepair
-
Anantha RW, Vassin VM, Borowiec JA. 2007. Sequential and synergistic modification of human RPA stimulates chromosomalDNArepair. J. Biol. Chem. 282:35910-35923. http://dx.doi.org/10.1074/jbc. M704645200.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35910-35923
-
-
Anantha, R.W.1
Vassin, V.M.2
Borowiec, J.A.3
-
56
-
-
33845991538
-
RPA2 is a direct downstream target forATRto regulate the S-phase checkpoint
-
Olson E, Nievera CJ, Klimovich V, Fanning E, Wu X. 2006. RPA2 is a direct downstream target forATRto regulate the S-phase checkpoint. J. Biol. Chem. 281:39517-39533. http://dx.doi.org/10.1074/jbc. M605121200.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 39517-39533
-
-
Olson, E.1
Nievera, C.J.2
Klimovich, V.3
Fanning, E.4
Wu, X.5
-
57
-
-
1342325347
-
Replication protein A (RPA) phosphorylation preventsRPAassociation with replication centers
-
Vassin VM, Wold MS, Borowiec JA. 2004. Replication protein A (RPA) phosphorylation preventsRPAassociation with replication centers. Mol. Cell. Biol. 24:1930-1943. http://dx.doi.org/10.1128/MCB.24.5.1930-1943.2004.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1930-1943
-
-
Vassin, V.M.1
Wold, M.S.2
Borowiec, J.A.3
-
58
-
-
0033104517
-
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA: DNA-PK complexes
-
Shao RG, Cao CX, Zhang H, Kohn KW, Wold MS, Pommier Y. 1999. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA: DNA-PK complexes. EMBO J. 18:1397-1406. http://dx.doi.org/10.1093/emboj/18.5.1397.
-
(1999)
EMBO J
, vol.18
, pp. 1397-1406
-
-
Shao, R.G.1
Cao, C.X.2
Zhang, H.3
Kohn, K.W.4
Wold, M.S.5
Pommier, Y.6
-
59
-
-
84861198042
-
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion
-
Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S. 2012. CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion. EMBO J. 31:2309-2321. http://dx.doi.org/10.1038/emboj.2012.96.
-
(2012)
EMBO J
, vol.31
, pp. 2309-2321
-
-
Gu, P.1
Min, J.N.2
Wang, Y.3
Huang, C.4
Peng, T.5
Chai, W.6
Chang, S.7
-
60
-
-
84870474851
-
Human CST has independent functions during telomere duplex replication and C-strand fill-in
-
Wang F, Stewart JA, Kasbek C, Zhao Y, Wright WE, Price CM. 2012. Human CST has independent functions during telomere duplex replication and C-strand fill-in. Cell Rep. 2:1096-1103. http://dx.doi.org/10.1016/j.celrep.2012.10.007.
-
(2012)
Cell Rep
, vol.2
, pp. 1096-1103
-
-
Wang, F.1
Stewart, J.A.2
Kasbek, C.3
Zhao, Y.4
Wright, W.E.5
Price, C.M.6
-
61
-
-
84866078802
-
Human CST promotes telomere duplex replication and general replication restart after fork stalling
-
Stewart JA, Wang F, Chaiken MF, Kasbek C, Chastain PD, II, Wright WE, Price CM. 2012. Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J. 31:3537-3549. http://dx.doi.org/10.1038/emboj.2012.215.
-
(2012)
EMBO J
, vol.31
, pp. 3537-3549
-
-
Stewart, J.A.1
Wang, F.2
Chaiken, M.F.3
Kasbek, C.4
Chastain II, P.D.5
Wright, W.E.6
Price, C.M.7
-
62
-
-
84870599782
-
Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in
-
Huang C, Dai X, Chai W. 2012. Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in. Cell Res. 22:1681-1695. http://dx.doi.org/10.1038/cr.2012.132.
-
(2012)
Cell Res
, vol.22
, pp. 1681-1695
-
-
Huang, C.1
Dai, X.2
Chai, W.3
-
63
-
-
84863393024
-
Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus
-
Anderson BH, Kasher PR, Mayer J, Szynkiewicz M, Jenkinson EM, Bhaskar SS, Urquhart JE, Daly SB, Dickerson JE, O'Sullivan J, Leibundgut EO, Muter J, Abdel-Salem GM, Babul-Hirji R, Baxter P, Berger A, Bonafe L, Brunstom-Hernandez JE, Buckard JA, Chitayat D, Chong WK, Cordelli DM, Ferreira P, Fluss J, Forrest EH, Franzoni E, Garone C, Hammans SR, Houge G, Hughes I, Jacquemont S, Jeannet PY, Jefferson RJ, Kumar R, Kutschke G, Lundberg S, Lourenco CM, Mehta R, Naidu S, Nischal KK, Nunes L, Ounap K, Philippart M, Prabhakar P, Risen SR, Schiffmann R, Soh C, Stephenson JB, Stewart H, Stone J, Tolmie JL, van der Knaap MS, Vieira JP, Vilain CN, Wakeling EL, Wermenbol V, Whitney A, Lovell SC, Meyer S, Livingston JH, Baerlocher GM, Black GC, Rice GI, Crow YJ. 2012. Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus. Nat. Genet. 44:338-342. http://dx.doi.org/10.1038/ng.1084.
-
(2012)
Nat. Genet.
, vol.44
, pp. 338-342
-
-
Anderson, B.H.1
Kasher, P.R.2
Mayer, J.3
Szynkiewicz, M.4
Jenkinson, E.M.5
Bhaskar, S.S.6
Urquhart, J.E.7
Daly, S.B.8
Dickerson, J.E.9
O'Sullivan, J.10
Leibundgut, E.O.11
Muter, J.12
Abdel-Salem, G.M.13
Babul-Hirji, R.14
Baxter, P.15
Berger, A.16
Bonafe, L.17
Brunstom-Hernandez, J.E.18
Buckard, J.A.19
Chitayat, D.20
Chong, W.K.21
Cordelli, D.M.22
Ferreira, P.23
Fluss, J.24
Forrest, E.H.25
Franzoni, E.26
Garone, C.27
Hammans, S.R.28
Houge, G.29
Hughes, I.30
Jacquemont, S.31
Jeannet, P.Y.32
Jefferson, R.J.33
Kumar, R.34
Kutschke, G.35
Lundberg, S.36
Lourenco, C.M.37
Mehta, R.38
Naidu, S.39
Nischal, K.K.40
Nunes, L.41
Ounap, K.42
Philippart, M.43
Prabhakar, P.44
Risen, S.R.45
Schiffmann, R.46
Soh, C.47
Stephenson, J.B.48
Stewart, H.49
Stone, J.50
Tolmie, J.L.51
van der Knaap, M.S.52
Vieira, J.P.53
Vilain, C.N.54
Wakeling, E.L.55
Wermenbol, V.56
Whitney, A.57
Lovell, S.C.58
Meyer, S.59
Livingston, J.H.60
Baerlocher, G.M.61
Black, G.C.62
Rice, G.I.63
Crow, Y.J.64
more..
-
64
-
-
84862266191
-
CTC1 mutations in a patient with dyskeratosis congenita
-
Keller RB, Gagne KE, Usmani GN, Asdourian GK, Williams DA, Hofmann I, Agarwal S. 2012. CTC1 mutations in a patient with dyskeratosis congenita. Pediatr. Blood Cancer 59:311-314. http://dx.doi.org/10.1002/pbc.24193.
-
(2012)
Pediatr. Blood Cancer.
, vol.59
, pp. 311-314
-
-
Keller, R.B.1
Gagne, K.E.2
Usmani, G.N.3
Asdourian, G.K.4
Williams, D.A.5
Hofmann, I.6
Agarwal, S.7
-
65
-
-
84858076515
-
Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts
-
Polvi A, Linnankivi T, Kivela T, Herva R, Keating JP, Makitie O, Pareyson D, Vainionpaa L, Lahtinen J, Hovatta I, Pihko H, Lehesjoki AE. 2012. Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts. Am. J. Hum. Genet. 90:540-549. http://dx.doi.org/10.1016/j.ajhg.2012.02.002.
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 540-549
-
-
Polvi, A.1
Linnankivi, T.2
Kivela, T.3
Herva, R.4
Keating, J.P.5
Makitie, O.6
Pareyson, D.7
Vainionpaa, L.8
Lahtinen, J.9
Hovatta, I.10
Pihko, H.11
Lehesjoki, A.E.12
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