메뉴 건너뛰기




Volumn 36, Issue 1, 2004, Pages 46-54

RPA regulates telomerase action by providing Est1p access to chromosome ends

Author keywords

[No Author keywords available]

Indexed keywords

CDC13P PROTEIN; CELL CYCLE PROTEIN; PROTEIN; PROTEIN EST1P; PROTEIN RFA2P; REPLICATION PROTEIN A; SINGLE STRANDED DNA BINDING PROTEIN; TELOMERASE; UNCLASSIFIED DRUG;

EID: 0347988057     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1284     Document Type: Article
Times cited : (122)

References (37)
  • 1
    • 0028072045 scopus 로고
    • Replication factor A is required in vivo for DNA replication, repair, and recombination
    • Longhese, M.P., Plevani, P. & Lucchini, G. Replication factor A is required in vivo for DNA replication, repair, and recombination. Mol. Cell. Biol. 14, 7884-7890 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7884-7890
    • Longhese, M.P.1    Plevani, P.2    Lucchini, G.3
  • 2
    • 0030908093 scopus 로고    scopus 로고
    • Replication protein A: A heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism
    • Wold, M.S. Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66, 61-92 (1997).
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 61-92
    • Wold, M.S.1
  • 3
    • 0033951868 scopus 로고    scopus 로고
    • Rothstein, R Characterization of genetic interactions with RFA1: The role of RPA in DNA replication and telomere maintenance
    • Smith, J., Zou, H. & Rothstein, R Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance. Biochimie 82, 71-78 (2000).
    • (2000) Biochimie , vol.82 , pp. 71-78
    • Smith, J.1    Zou, H.2
  • 4
    • 0025950546 scopus 로고
    • Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase
    • Brill, SJ. & Stillman, B. Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase. Genes Dev. 5, 1589-1600 (1991).
    • (1991) Genes Dev. , vol.5 , pp. 1589-1600
    • Brill, S.J.1    Stillman, B.2
  • 5
    • 0030479885 scopus 로고    scopus 로고
    • The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast
    • Brush, G.S., Morrow, D.M., Hieter, P. & Kelly, T.J. The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. Proc. Natl. Acad. Sci. USA 93, 15075-15080 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15075-15080
    • Brush, G.S.1    Morrow, D.M.2    Hieter, P.3    Kelly, T.J.4
  • 6
    • 0034307720 scopus 로고    scopus 로고
    • Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response
    • Brush, G. S. & Kelly, T.J. Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response. Nucleic Acids Res. 19, 3725-3732 (2000).
    • (2000) Nucleic Acids Res. , vol.19 , pp. 3725-3732
    • Brush, G.S.1    Kelly, T.J.2
  • 7
    • 0035584046 scopus 로고    scopus 로고
    • Replication protein A is sequentially phosphorylated during meiosis
    • Brush, G.S., Clifford, D.M., Marinco, S.M. & Bartrand, A.J. Replication protein A is sequentially phosphorylated during meiosis. Nucleic Acids Res. 29, 4808-4817 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4808-4817
    • Brush, G.S.1    Clifford, D.M.2    Marinco, S.M.3    Bartrand, A.J.4
  • 8
    • 0035878060 scopus 로고    scopus 로고
    • The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes
    • Schramke, V. et al. The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev. 15, 1845-1858 (2001)
    • (2001) Genes Dev. , vol.15 , pp. 1845-1858
    • Schramke, V.1
  • 10
    • 0032522443 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase: Components and regulation
    • Nugent, C.I. & Lundblad, V. The telomerase reverse transcriptase: components and regulation. Genes Dev. 12, 1073-1085 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 1073-1085
    • Nugent, C.I.1    Lundblad, V.2
  • 11
    • 0031264204 scopus 로고    scopus 로고
    • Synthesis of the telomeric C-strand. A review
    • Price, C.M. Synthesis of the telomeric C-strand. A review. Biochemistry 62, 1216-1223 (1997).
    • (1997) Biochemistry , vol.62 , pp. 1216-1223
    • Price, C.M.1
  • 13
    • 0030447657 scopus 로고    scopus 로고
    • 1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
    • 1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc. Natl. Acad. Sci. USA 93, 13760-13765 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13760-13765
    • Lin, J.J.1    Zakian, V.A.2
  • 14
    • 0033214013 scopus 로고    scopus 로고
    • Est1 and Cdc13 as comediators of telomerase access
    • Evans, S.K. & Lundblad, V. Est1 and Cdc13 as comediators of telomerase access. Science 286, 117-120 (1999).
    • (1999) Science , vol.286 , pp. 117-120
    • Evans, S.K.1    Lundblad, V.2
  • 15
    • 0035830494 scopus 로고    scopus 로고
    • Cdc13 delivers separate complexes to the telomere for end protection and replication
    • Pennock, E., Buckley, K. & Lundblad, V. Cdc13 delivers separate complexes to the telomere for end protection and replication. Cell 104, 387-396 (2001).
    • (2001) Cell , vol.104 , pp. 387-396
    • Pennock, E.1    Buckley, K.2    Lundblad, V.3
  • 16
    • 0033564210 scopus 로고    scopus 로고
    • Progressive cis-inhibition of telomerase upon telomere elongation
    • Marcand, S., Brevet, V. & Gilson, E. Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J. 18, 3509-3519 (1999).
    • (1999) EMBO J. , vol.18 , pp. 3509-3519
    • Marcand, S.1    Brevet, V.2    Gilson, E.3
  • 17
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ
    • Diede, S.J. & Gottschling, D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ. Cell 99, 723-733 (1999).
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 18
    • 0037047643 scopus 로고    scopus 로고
    • Est1p as a cell cycle-regulated activator of telomere-bound telomerase
    • Taggart, A.K., Teng, S.C. & Zakian V.A. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 297,1023-1026 (2002)
    • (2002) Science , vol.297 , pp. 1023-1026
    • Taggart, A.K.1    Teng, S.C.2    Zakian, V.A.3
  • 19
    • 0037326054 scopus 로고    scopus 로고
    • Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae
    • Smith, C.D, Smith, D.L., DeRisi, J.L. & Blackburn, E.H. Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae. Mol. Biol. Cell. 14, 556-570 (2003).
    • (2003) Mol. Biol. Cell. , vol.14 , pp. 556-570
    • Smith, C.D.1    Smith, D.L.2    DeRisi, J.L.3    Blackburn, E.H.4
  • 20
    • 0031810967 scopus 로고    scopus 로고
    • Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo
    • Bourns, B.D., Alexander, M.K., Smith, A.M. & Zakian, V.A. Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo. Mol. Cell. Biol. 18, 5600-5608 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5600-5608
    • Bourns, B.D.1    Alexander, M.K.2    Smith, A.M.3    Zakian, V.A.4
  • 21
    • 0032076127 scopus 로고    scopus 로고
    • Yeast Ku as a regulator of chromosomal DNA end structure
    • Gravel, S., Larrivee, M., Labrecque, P. & Wellinger, R.J. Yeast Ku as a regulator of chromosomal DNA end structure. Science 280, 741-744 (1998).
    • (1998) Science , vol.280 , pp. 741-744
    • Gravel, S.1    Larrivee, M.2    Labrecque, P.3    Wellinger, R.J.4
  • 22
    • 0034733606 scopus 로고    scopus 로고
    • Telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang
    • Huffman, K.E., Levene, S.D., Tesmer, V.M., Shay, J.W. & Wright, W.E. Telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang. J. Biol. Chem. 275, 19719-19722 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 19719-19722
    • Huffman, K.E.1    Levene, S.D.2    Tesmer, V.M.3    Shay, J.W.4    Wright, W.E.5
  • 23
    • 0029088371 scopus 로고
    • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene
    • Greenwell, P.W. et al. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82, 823-829 (1995).
    • (1995) Cell , vol.82 , pp. 823-829
    • Greenwell, P.W.1
  • 24
    • 0344423818 scopus 로고    scopus 로고
    • Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae
    • Craven, R.J. & Pates, T.D. Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. Genetics 152, 1531-1541 (1999).
    • (1999) Genetics , vol.152 , pp. 1531-1541
    • Craven, R.J.1    Pates, T.D.2
  • 25
    • 0035158605 scopus 로고    scopus 로고
    • The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku
    • Peterson, S.E. et al The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nat. Genet. 27, 64-67 (2001).
    • (2001) Nat. Genet. , vol.27 , pp. 64-67
    • Peterson, S.E.1
  • 26
    • 0032474732 scopus 로고    scopus 로고
    • The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
    • Polotnianka, R.M, Li, J. & Lustig, A.J. The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities. Curr. Biol. 8, 831-834 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 831-834
    • Polotnianka, R.M.1    Li, J.2    Lustig, A.J.3
  • 27
    • 0026583949 scopus 로고
    • Interaction of DNA polymerase α-primase with cellular replication protein A and SV40-T antigen
    • Dornreiter, I. et al. Interaction of DNA polymerase α-primase with cellular replication protein A and SV40-T antigen. EMBO J. 11, 769-776 (1992).
    • (1992) EMBO J. , vol.11 , pp. 769-776
    • Dornreiter, I.1
  • 28
    • 0029791693 scopus 로고    scopus 로고
    • The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoints in budding yeast
    • Longhese, M.P., Neecke, H., Paciotti, V., Lucchini, G. & Plevani, P. The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoints in budding yeast. Nucleic Acids Res. 24, 3533-3537 (1996).
    • (1996) Nucleic Acids Res. , vol.24 , pp. 3533-3537
    • Longhese, M.P.1    Neecke, H.2    Paciotti, V.3    Lucchini, G.4    Plevani, P.5
  • 29
    • 0034013797 scopus 로고    scopus 로고
    • The Mre11p/Rad50p/Xrs2p complex and the Tellp function in a single pathway for telomere maintenance in yeast
    • Ritchie, K.B. & Petes, T.D. The Mre11p/Rad50p/Xrs2p complex and the Tellp function in a single pathway for telomere maintenance in yeast Genetics 155, 475-479 (2000).
    • (2000) Genetics , vol.155 , pp. 475-479
    • Ritchie, K.B.1    Petes, T.D.2
  • 30
    • 0035928740 scopus 로고    scopus 로고
    • Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
    • Chan, S.W., Chang, J, Prescott, J. & Blackburn, E.H. Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr. Biol. 11, 1240-1250 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1240-1250
    • Chan, S.W.1    Chang, J.2    Prescott, J.3    Blackburn, E.H.4
  • 31
    • 0035806977 scopus 로고    scopus 로고
    • The role of the Mrel 1-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres
    • Tsukamoto, Y., Taggart, A.K & Zakian, V.A. The role of the Mrel 1-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres. Curr. Biol. 11, 1328-1335 (2001).
    • (2001) Curr. Biol. , vol.11 , pp. 1328-1335
    • Tsukamoto, Y.1    Taggart, A.K.2    Zakian, V.A.3
  • 32
    • 0030930990 scopus 로고    scopus 로고
    • Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae
    • Maniar, H.S., Wilson, R, & Brill, S. J. Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae. Genetics 145, 891-902 (1997).
    • (1997) Genetics , vol.145 , pp. 891-902
    • Maniar, H.S.1    Wilson, R.2    Brill, S.J.3
  • 33
    • 0042379940 scopus 로고    scopus 로고
    • Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae
    • Mallory, J.C. et al. Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. DNA Repair 2, 1041-1064 (2003).
    • (2003) DNA Repair , vol.2 , pp. 1041-1064
    • Mallory, J.C.1
  • 34
    • 0037381155 scopus 로고    scopus 로고
    • A human homolog of yeast est1p associates with telomerase and uncaps chromosome ends when overexpressed
    • Reichenbach, P. et al. A human homolog of yeast est1p associates with telomerase and uncaps chromosome ends when overexpressed, Curr. Biol. 13, 568-574 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 568-574
    • Reichenbach, P.1
  • 35
    • 0037447232 scopus 로고    scopus 로고
    • Functional conservation of the telomerase protein est 1p in humans
    • Snow, B, E. et al. Functional conservation of the telomerase protein est1p in humans. Curr. Biol. 13, 698-704 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 698-704
    • Snow, B.E.1
  • 36
    • 0032167423 scopus 로고    scopus 로고
    • Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases
    • Tanaka, T. & Nasmyth, K. Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. EMBOJ. 17, 5182-5191 (1998).
    • (1998) EMBO J. , vol.17 , pp. 5182-5191
    • Tanaka, T.1    Nasmyth, K.2
  • 37
    • 0033612287 scopus 로고    scopus 로고
    • Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
    • Martin, S.G., Laroche, T., Suka, N., Grurstein, M, & Gasser, S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621-633 (1999).
    • (1999) Cell , vol.97 , pp. 621-633
    • Martin, S.G.1    Laroche, T.2    Suka, N.3    Grurstein, M.4    Gasser, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.