-
1
-
-
0037357426
-
Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models
-
Seril DN, Liao J, Yang GY, et al. Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models. Carcinogenesis. 2003; 24: 353-62.
-
(2003)
Carcinogenesis
, vol.24
, pp. 353-362
-
-
Seril, D.N.1
Liao, J.2
Yang, G.Y.3
-
2
-
-
46749095883
-
Oxidative stress in ulcerative colitis-associated carcinogenesis
-
Roessner A, Kuester D, Malfertheiner P, et al. Oxidative stress in ulcerative colitis-associated carcinogenesis. Pathol Res Pract. 2008; 204: 511-24.
-
(2008)
Pathol Res Pract
, vol.204
, pp. 511-524
-
-
Roessner, A.1
Kuester, D.2
Malfertheiner, P.3
-
3
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144: 646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
84867103263
-
Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer
-
Rubin DC, Shaker A, Levin MS. Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer. Front Immunol. 2012; 3: 107.
-
(2012)
Front Immunol
, vol.3
, pp. 107
-
-
Rubin, D.C.1
Shaker, A.2
Levin, M.S.3
-
5
-
-
75849117800
-
Inflammation and oncogenesis: a vicious connection
-
Grivennikov SI, Karin M. Inflammation and oncogenesis: a vicious connection. Curr Opin Genet Dev. 2010; 20: 65-71.
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 65-71
-
-
Grivennikov, S.I.1
Karin, M.2
-
6
-
-
84865534083
-
Chronic epithelial NF-kappaB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation
-
Shaked H, Hofseth LJ, Chumanevich A, et al. Chronic epithelial NF-kappaB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci USA. 2012; 109: 14007-12.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 14007-14012
-
-
Shaked, H.1
Hofseth, L.J.2
Chumanevich, A.3
-
7
-
-
84863582087
-
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer
-
Mangerich A, Knutson CG, Parry NM, et al. Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. Proc Natl Acad Sci USA. 2012; 109: 1820-9.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1820-1829
-
-
Mangerich, A.1
Knutson, C.G.2
Parry, N.M.3
-
8
-
-
46749127004
-
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
-
Meira LB, Bugni JM, Green SL, et al. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest. 2008; 118: 2516-25.
-
(2008)
J Clin Invest
, vol.118
, pp. 2516-2525
-
-
Meira, L.B.1
Bugni, J.M.2
Green, S.L.3
-
9
-
-
84880775004
-
Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis
-
Poehlmann A, Reissig K, Just A, et al. Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. J Cell Mol Med. 2013; 17: 901-13.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 901-913
-
-
Poehlmann, A.1
Reissig, K.2
Just, A.3
-
10
-
-
33745845132
-
Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis
-
Furth EE, Gustafson KS, Dai CY, et al. Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis. Neoplasia. 2006; 8: 429-36.
-
(2006)
Neoplasia
, vol.8
, pp. 429-436
-
-
Furth, E.E.1
Gustafson, K.S.2
Dai, C.Y.3
-
11
-
-
39049192011
-
In vitro effects of dextran sulfate sodium on a Caco-2 cell line and plausible mechanisms for dextran sulfate sodium-induced colitis
-
Araki Y, Sugihara H, Hattori T. In vitro effects of dextran sulfate sodium on a Caco-2 cell line and plausible mechanisms for dextran sulfate sodium-induced colitis. Oncol Rep. 2006; 16: 1357-62.
-
(2006)
Oncol Rep
, vol.16
, pp. 1357-1362
-
-
Araki, Y.1
Sugihara, H.2
Hattori, T.3
-
12
-
-
84866442814
-
Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis
-
Araki Y, Bamba T, Mukaisho KI, et al. Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis. Oncol Rep. 2012; 28: 1597-605.
-
(2012)
Oncol Rep
, vol.28
, pp. 1597-1605
-
-
Araki, Y.1
Bamba, T.2
Mukaisho, K.I.3
-
13
-
-
77956011024
-
Importance of DNA damage checkpoints in the pathogenesis of human cancers
-
Poehlmann A, Roessner A. Importance of DNA damage checkpoints in the pathogenesis of human cancers. Pathol Res Pract. 2010; 206: 591-601.
-
(2010)
Pathol Res Pract
, vol.206
, pp. 591-601
-
-
Poehlmann, A.1
Roessner, A.2
-
14
-
-
84862307800
-
Eukaryotic DNA damage checkpoint activation in response to double-strand breaks
-
Finn K, Lowndes NF, Grenon M. Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Cell Mol Life Sci. 2012; 69: 1447-73.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 1447-1473
-
-
Finn, K.1
Lowndes, N.F.2
Grenon, M.3
-
15
-
-
81055155450
-
Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair
-
Langerak P, Russell P. Regulatory networks integrating cell cycle control with DNA damage checkpoints and double-strand break repair. Philos Trans R Soc Lond B Biol Sci. 2011; 366: 3562-71.
-
(2011)
Philos Trans R Soc Lond B Biol Sci
, vol.366
, pp. 3562-3571
-
-
Langerak, P.1
Russell, P.2
-
16
-
-
1442354963
-
Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo
-
Dmitrieva NI, Cai Q, Burg MB. Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo. Proc Natl Acad Sci USA. 2004; 101: 2317-22.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2317-2322
-
-
Dmitrieva, N.I.1
Cai, Q.2
Burg, M.B.3
-
17
-
-
39849098748
-
Role of the JNK signal transduction pathway in inflammatory bowel disease
-
Roy PK, Rashid F, Bragg J, et al. Role of the JNK signal transduction pathway in inflammatory bowel disease. World J Gastroenterol. 2008; 14: 200-2.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 200-202
-
-
Roy, P.K.1
Rashid, F.2
Bragg, J.3
-
18
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature. 2001; 410: 37-40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
19
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell. 2000; 103: 239-52.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
20
-
-
0037230304
-
Activation of the JNK signaling pathway: breaking the brake on apoptosis
-
Lin A. Activation of the JNK signaling pathway: breaking the brake on apoptosis. BioEssays. 2003; 25: 17-24.
-
(2003)
BioEssays
, vol.25
, pp. 17-24
-
-
Lin, A.1
-
21
-
-
33748942862
-
The isoform-specific functions of the c-Jun N-terminal kinases (JNKs): differences revealed by gene targeting
-
Bogoyevitch MA. The isoform-specific functions of the c-Jun N-terminal kinases (JNKs): differences revealed by gene targeting. BioEssays. 2006; 28: 923-34.
-
(2006)
BioEssays
, vol.28
, pp. 923-934
-
-
Bogoyevitch, M.A.1
-
22
-
-
21344474327
-
From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance
-
Karin M, Gallagher E. From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance. IUBMB Life. 2005; 57: 283-95.
-
(2005)
IUBMB Life
, vol.57
, pp. 283-295
-
-
Karin, M.1
Gallagher, E.2
-
23
-
-
0033969883
-
Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner
-
Potapova O, Gorospe M, Dougherty RH, et al. Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner. Mol Cell Biol. 2000; 20: 1713-22.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1713-1722
-
-
Potapova, O.1
Gorospe, M.2
Dougherty, R.H.3
-
24
-
-
0346606862
-
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease
-
Hussain SP, Amstad P, Raja K, et al. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res. 2000; 60: 3333-7.
-
(2000)
Cancer Res
, vol.60
, pp. 3333-3337
-
-
Hussain, S.P.1
Amstad, P.2
Raja, K.3
-
26
-
-
33645757326
-
Malignant transformation of human colon epithelial cells by benzo[c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Herbst U, Fuchs JI, Teubner W, et al. Malignant transformation of human colon epithelial cells by benzo[c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine. Toxicol Appl Pharmacol. 2006; 212: 136-45.
-
(2006)
Toxicol Appl Pharmacol
, vol.212
, pp. 136-145
-
-
Herbst, U.1
Fuchs, J.I.2
Teubner, W.3
-
27
-
-
42349108450
-
Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis
-
Habold C, Poehlmann A, Bajbouj K, et al. Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. J Cell Mol Med. 2008; 12: 607-21.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 607-621
-
-
Habold, C.1
Poehlmann, A.2
Bajbouj, K.3
-
28
-
-
79959416307
-
Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G(2) checkpoint arrest
-
Poehlmann A, Habold C, Walluscheck D, et al. Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G(2) checkpoint arrest. J Cell Mol Med. 2011; 15: 1528-41.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1528-1541
-
-
Poehlmann, A.1
Habold, C.2
Walluscheck, D.3
-
29
-
-
77953529599
-
Tumor initiation via loss of cell contact inhibition versus Ras mutation: do all roads lead to EMT?
-
Liu Y, Dean DC. Tumor initiation via loss of cell contact inhibition versus Ras mutation: do all roads lead to EMT? Cell Cycle. 2010; 9: 897-900.
-
(2010)
Cell Cycle
, vol.9
, pp. 897-900
-
-
Liu, Y.1
Dean, D.C.2
-
30
-
-
73349130483
-
Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat
-
Seluanov A, Hine C, Azpurua J, et al. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proc Natl Acad Sci USA. 2009; 106: 19352-7.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19352-19357
-
-
Seluanov, A.1
Hine, C.2
Azpurua, J.3
-
31
-
-
43749092334
-
Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
-
Mates JM, Segura JA, Alonso FJ, et al. Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis. Arch Toxicol. 2008; 82: 273-99.
-
(2008)
Arch Toxicol
, vol.82
, pp. 273-299
-
-
Mates, J.M.1
Segura, J.A.2
Alonso, F.J.3
-
32
-
-
34248396033
-
Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy
-
Lopez-Lazaro M. Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy. Cancer Lett. 2007; 252: 1-8.
-
(2007)
Cancer Lett
, vol.252
, pp. 1-8
-
-
Lopez-Lazaro, M.1
-
33
-
-
0041524094
-
A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun
-
Morton S, Davis RJ, McLaren A, et al. A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun. EMBO J. 2003; 22: 3876-86.
-
(2003)
EMBO J
, vol.22
, pp. 3876-3886
-
-
Morton, S.1
Davis, R.J.2
McLaren, A.3
-
34
-
-
69449101810
-
The links between transcription, beta-catenin/JNK signaling, and carcinogenesis
-
Saadeddin A, Babaei-Jadidi R, Spencer-Dene B, et al. The links between transcription, beta-catenin/JNK signaling, and carcinogenesis. Mol Cancer Res. 2009; 7: 1189-96.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1189-1196
-
-
Saadeddin, A.1
Babaei-Jadidi, R.2
Spencer-Dene, B.3
-
35
-
-
57349146621
-
A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression
-
Yochum GS, Cleland R, Goodman RH. A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol. 2008; 28: 7368-79.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7368-7379
-
-
Yochum, G.S.1
Cleland, R.2
Goodman, R.H.3
-
36
-
-
84856070960
-
p38alpha mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway
-
Gutierrez-Uzquiza A, Arechederra M, Bragado P, et al. p38alpha mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathway. J Biol Chem. 2012; 287: 2632-42.
-
(2012)
J Biol Chem
, vol.287
, pp. 2632-2642
-
-
Gutierrez-Uzquiza, A.1
Arechederra, M.2
Bragado, P.3
-
37
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
Meloche S, Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene. 2007; 26: 3227-39.
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouyssegur, J.2
-
38
-
-
33645828828
-
The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis
-
Assi K, Pillai R, Gomez-Munoz A, et al. The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis. Immunology. 2006; 118: 112-21.
-
(2006)
Immunology
, vol.118
, pp. 112-121
-
-
Assi, K.1
Pillai, R.2
Gomez-Munoz, A.3
-
39
-
-
84858133686
-
The JNK inhibitor XG-102 protects against TNBS-induced colitis
-
Reinecke K, Eminel S, Dierck F, et al. The JNK inhibitor XG-102 protects against TNBS-induced colitis. PLoS ONE. 2012; 7: e30985.
-
(2012)
PLoS ONE
, vol.7
-
-
Reinecke, K.1
Eminel, S.2
Dierck, F.3
-
40
-
-
0037337694
-
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway
-
Kennedy NJ, Sluss HK, Jones SN, et al. Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. Genes Dev. 2003; 17: 629-37.
-
(2003)
Genes Dev
, vol.17
, pp. 629-637
-
-
Kennedy, N.J.1
Sluss, H.K.2
Jones, S.N.3
-
41
-
-
34547653108
-
c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression
-
Tong C, Yin Z, Song Z, et al. c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. Am J Pathol. 2007; 171: 297-303.
-
(2007)
Am J Pathol
, vol.171
, pp. 297-303
-
-
Tong, C.1
Yin, Z.2
Song, Z.3
-
42
-
-
84864198388
-
A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches
-
Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 2012; 143: 307-20.
-
(2012)
Gastroenterology
, vol.143
, pp. 307-320
-
-
Seki, E.1
Brenner, D.A.2
Karin, M.3
-
43
-
-
57449109370
-
Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation
-
Hui L, Zatloukal K, Scheuch H, et al. Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation. J Clin Invest. 2008; 118: 3943-53.
-
(2008)
J Clin Invest
, vol.118
, pp. 3943-3953
-
-
Hui, L.1
Zatloukal, K.2
Scheuch, H.3
-
44
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53 dependent
-
Schreiber M, Kolbus A, Piu F, et al. Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev. 1999; 13: 607-19.
-
(1999)
Genes Dev
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
Kolbus, A.2
Piu, F.3
-
45
-
-
7944234858
-
Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon
-
Poole AJ, Heap D, Carroll RE, et al. Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon. Oncogene. 2004; 23: 8128-34.
-
(2004)
Oncogene
, vol.23
, pp. 8128-8134
-
-
Poole, A.J.1
Heap, D.2
Carroll, R.E.3
-
46
-
-
20144384882
-
Lost in transcription: p21 repression, mechanisms, and consequences
-
Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res. 2005; 65: 3980-5.
-
(2005)
Cancer Res
, vol.65
, pp. 3980-3985
-
-
Gartel, A.L.1
Radhakrishnan, S.K.2
-
47
-
-
0038545778
-
Cyclin D1 and p21 in ulcerative colitis-related inflammation and epithelial neoplasia: a study of aberrant expression and underlying mechanisms
-
Wong NA, Mayer NJ, Anderson CE, et al. Cyclin D1 and p21 in ulcerative colitis-related inflammation and epithelial neoplasia: a study of aberrant expression and underlying mechanisms. Hum Pathol. 2003; 34: 580-8.
-
(2003)
Hum Pathol
, vol.34
, pp. 580-588
-
-
Wong, N.A.1
Mayer, N.J.2
Anderson, C.E.3
-
48
-
-
33749043459
-
Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer
-
Ogino S, Kawasaki T, Kirkner GJ, et al. Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer. J Pathol. 2006; 210: 147-54.
-
(2006)
J Pathol
, vol.210
, pp. 147-154
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
-
49
-
-
79951626443
-
Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis
-
Kawamata S, Matsuzaki K, Murata M, et al. Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis. Inflamm Bowel Dis. 2011; 17: 683-95.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 683-695
-
-
Kawamata, S.1
Matsuzaki, K.2
Murata, M.3
-
50
-
-
61849113179
-
CARMA1-mediated NF-kappaB and JNK activation in lymphocytes
-
Blonska M, Lin X. CARMA1-mediated NF-kappaB and JNK activation in lymphocytes. Immunol Rev. 2009; 228: 199-211.
-
(2009)
Immunol Rev
, vol.228
, pp. 199-211
-
-
Blonska, M.1
Lin, X.2
-
51
-
-
4444341881
-
Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
-
Sabapathy K, Hochedlinger K, Nam SY, et al. Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Mol Cell. 2004; 15: 713-25.
-
(2004)
Mol Cell
, vol.15
, pp. 713-725
-
-
Sabapathy, K.1
Hochedlinger, K.2
Nam, S.Y.3
-
52
-
-
84872299710
-
Immediate early response genes and cell transformation
-
Healy S, Khan P, Davie JR. Immediate early response genes and cell transformation. Pharmacol Ther. 2013; 137: 64-77.
-
(2013)
Pharmacol Ther
, vol.137
, pp. 64-77
-
-
Healy, S.1
Khan, P.2
Davie, J.R.3
-
53
-
-
18444411948
-
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38
-
Ouwens DM, de Ruiter ND, van der Zon GC, et al. Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. EMBO J. 2002; 21: 3782-93.
-
(2002)
EMBO J
, vol.21
, pp. 3782-3793
-
-
Ouwens, D.M.1
de Ruiter, N.D.2
van der Zon, G.C.3
-
54
-
-
0033521651
-
c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
-
Wisdom R, Johnson RS, Moore C. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 1999; 18: 188-97.
-
(1999)
EMBO J
, vol.18
, pp. 188-197
-
-
Wisdom, R.1
Johnson, R.S.2
Moore, C.3
-
55
-
-
0024276523
-
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
-
Angel P, Hattori K, Smeal T, et al. The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell. 1988; 55: 875-85.
-
(1988)
Cell
, vol.55
, pp. 875-885
-
-
Angel, P.1
Hattori, K.2
Smeal, T.3
-
56
-
-
0029998491
-
Cellular transformation and malignancy induced by ras require c-jun
-
Johnson R, Spiegelman B, Hanahan D, et al. Cellular transformation and malignancy induced by ras require c-jun. Mol Cell Biol. 1996; 16: 4504-11.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4504-4511
-
-
Johnson, R.1
Spiegelman, B.2
Hanahan, D.3
-
57
-
-
0037462454
-
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
-
Eferl R, Ricci R, Kenner L, et al. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell. 2003; 112: 181-92.
-
(2003)
Cell
, vol.112
, pp. 181-192
-
-
Eferl, R.1
Ricci, R.2
Kenner, L.3
-
58
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
Shaulian E, Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol. 2002; 4: E131-6.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Shaulian, E.1
Karin, M.2
-
59
-
-
0033638915
-
The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest
-
Shaulian E, Schreiber M, Piu F, et al. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell. 2000; 103: 897-907.
-
(2000)
Cell
, vol.103
, pp. 897-907
-
-
Shaulian, E.1
Schreiber, M.2
Piu, F.3
-
60
-
-
84888202743
-
ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells
-
Walluscheck D, Poehlmann A, Hartig R, et al. ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells. J Cell Mol Med. 2013; 17: 976-88.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 976-988
-
-
Walluscheck, D.1
Poehlmann, A.2
Hartig, R.3
-
62
-
-
84874516222
-
Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells
-
Chakilam S, Gandesiri M, Rau TT, et al. Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells. Am J Pathol. 2013; 182: 1005-20.
-
(2013)
Am J Pathol
, vol.182
, pp. 1005-1020
-
-
Chakilam, S.1
Gandesiri, M.2
Rau, T.T.3
-
63
-
-
44749090905
-
Sp1: emerging roles-beyond constitutive activation of TATA-less housekeeping genes
-
Wierstra I. Sp1: emerging roles-beyond constitutive activation of TATA-less housekeeping genes. Biochem Biophys Res Commun. 2008; 372: 1-13.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 1-13
-
-
Wierstra, I.1
-
64
-
-
34250702714
-
Wnt pathway-related gene expression during malignant progression in ulcerative colitis
-
van Dekken H, Wink JC, Vissers KJ, et al. Wnt pathway-related gene expression during malignant progression in ulcerative colitis. Acta Histochem. 2007; 109: 266-72.
-
(2007)
Acta Histochem
, vol.109
, pp. 266-272
-
-
van Dekken, H.1
Wink, J.C.2
Vissers, K.J.3
-
65
-
-
78049250336
-
Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss
-
Cole AM, Myant K, Reed KR, et al. Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss. Cancer Res. 2010; 70: 8149-58.
-
(2010)
Cancer Res
, vol.70
, pp. 8149-8158
-
-
Cole, A.M.1
Myant, K.2
Reed, K.R.3
-
66
-
-
84878775181
-
2 metabolism in skeletal muscle mitochondria
-
2 metabolism in skeletal muscle mitochondria. FEBS Lett. 2013; 587: 1799-804.
-
(2013)
FEBS Lett
, vol.587
, pp. 1799-1804
-
-
Banh, S.1
Treberg, J.R.2
-
67
-
-
0025047493
-
Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions
-
Gillies RJ, Martinez-Zaguilan R, Martinez GM, et al. Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proc Natl Acad Sci USA. 1990; 87: 7414-8.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7414-7418
-
-
Gillies, R.J.1
Martinez-Zaguilan, R.2
Martinez, G.M.3
|