Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis

Oncology Reports

Volumn 28, Issue 5, 2012, Pages 1597-1605

  Araki, Yoshio ^a   Bamba, Tadao ^a   Mukaisho, Ken Ichi ^a   Kanauchi, Osamu ^b   Ban, Hiromitsu ^a   Bamba, Shigeki ^a   Andoh, Akira ^a   Fujiyama, Yoshihide ^a   Hattori, Takanori ^a   Sugihara, Hiroyuki ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KIRIN HOLDINGS CO LTD   (Japan)

Author keywords

Apoptosis; Cell cycle arrest; Crypt disappearance; Depolymerization; Dextran sulfate sodium; DSS induced colitis; Molecular mass

Indexed keywords

2 AMINOPYRIDINE; DEXTRAN SULFATE; MONOCLONAL ANTIBODY KI 67;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL STRAIN CACO 2; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DISEASE SEVERITY; ENERGY METABOLISM; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTESTINE ABSORPTION; MALE; MITOSIS; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; WEIGHT REDUCTION;

ADMINISTRATION, ORAL; AMINOPYRIDINES; ANIMALS; APOPTOSIS; CACO-2 CELLS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED BALB C;

EID: 84866442814     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1969     Document Type: Article

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