-
1
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
Sharpless NE, DePinho RA (2007) How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 8(9):703-713.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.9
, pp. 703-713
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
2
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
Rossi DJ, et al. (2005) Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci USA 102(26):9194-9199.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.26
, pp. 9194-9199
-
-
Rossi, D.J.1
-
3
-
-
35848943667
-
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging
-
Rossi DJ, et al. (2007) Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle 6(19): 2371-2376.
-
(2007)
Cell Cycle
, vol.6
, Issue.19
, pp. 2371-2376
-
-
Rossi, D.J.1
-
4
-
-
13244287677
-
Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche
-
Nishimura EK, Granter SR, Fisher DE (2005) Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche. Science 307(5710):720-724.
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 720-724
-
-
Nishimura, E.K.1
Granter, S.R.2
Fisher, D.E.3
-
5
-
-
33744513898
-
Age-Related impairment of mesenchymal progenitor cell function
-
Stolzing A, Scutt A (2006) Age-Related impairment of mesenchymal progenitor cell function. Aging Cell 5(3):213-224.
-
(2006)
Aging Cell
, vol.5
, Issue.3
, pp. 213-224
-
-
Stolzing, A.1
Scutt, A.2
-
6
-
-
12144291084
-
Cardiac stem cell and myocyte aging, heart failure, and insulinlike growth factor-1 overexpression
-
Torella D, et al. (2004) Cardiac stem cell and myocyte aging, heart failure, and insulinlike growth factor-1 overexpression. Circ Res 94(4):514-524.
-
(2004)
Circ Res
, vol.94
, Issue.4
, pp. 514-524
-
-
Torella, D.1
-
7
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy IM, et al. (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433(7027):760-764.
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 760-764
-
-
Conboy, I.M.1
-
8
-
-
84862908705
-
Rejuvenation of regeneration in the aging central nervous system
-
Ruckh JM, et al. (2012) Rejuvenation of regeneration in the aging central nervous system. Cell Stem Cell 10(1):96-103.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.1
, pp. 96-103
-
-
Ruckh, J.M.1
-
9
-
-
80052410357
-
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
-
Villeda SA, et al. (2011) The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477(7362):90-94.
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 90-94
-
-
Villeda, S.A.1
-
10
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack AS, et al. (2007) Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317(5839):807-810.
-
(2007)
Science
, vol.317
, Issue.5839
, pp. 807-810
-
-
Brack, A.S.1
-
11
-
-
84877687210
-
Growth differentiation factor 11 is a circulating factor that reverses age-Related cardiac hypertrophy
-
Loffredo FS, et al. (2013) Growth differentiation factor 11 is a circulating factor that reverses age-Related cardiac hypertrophy. Cell 153(4):828-839.
-
(2013)
Cell
, vol.153
, Issue.4
, pp. 828-839
-
-
Loffredo, F.S.1
-
13
-
-
33644978738
-
The hair cycle
-
Alonso L, Fuchs E (2006) The hair cycle. J Cell Sci 119(Pt 3):391-393.
-
(2006)
J Cell Sci
, vol.119
, Issue.PART 3
, pp. 391-393
-
-
Alonso, L.1
Fuchs, E.2
-
14
-
-
0025313294
-
Label-Retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
-
Cotsarelis G, Sun TT, Lavker RM (1990) Label-Retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61(7):1329-1337.
-
(1990)
Cell
, vol.61
, Issue.7
, pp. 1329-1337
-
-
Cotsarelis, G.1
Sun, T.T.2
Lavker, R.M.3
-
15
-
-
0347634454
-
Defining the epithelial stem cell niche in skin
-
Tumbar T, et al. (2004) Defining the epithelial stem cell niche in skin. Science 303(5656):359-363.
-
(2004)
Science
, vol.303
, Issue.5656
, pp. 359-363
-
-
Tumbar, T.1
-
16
-
-
4444290010
-
Self-Renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
-
Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E (2004) Self-Renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118(5):635-648.
-
(2004)
Cell
, vol.118
, Issue.5
, pp. 635-648
-
-
Blanpain, C.1
Lowry, W.E.2
Geoghegan, A.3
Polak, L.4
Fuchs, E.5
-
17
-
-
1842529559
-
Capturing and profiling adult hair follicle stemcells
-
Morris RJ, et al. (2004) Capturing and profiling adult hair follicle stemcells. Nat Biotechnol 22(4):411-417.
-
(2004)
Nat Biotechnol
, vol.22
, Issue.4
, pp. 411-417
-
-
Morris, R.J.1
-
18
-
-
69249202346
-
Distinct self-Renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells
-
Zhang YV, Cheong J, Ciapurin N, McDermitt DJ, Tumbar T (2009) Distinct self-Renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells. Cell Stem Cell 5(3):267-278.
-
(2009)
Cell Stem Cell
, vol.5
, Issue.3
, pp. 267-278
-
-
Zhang, Y.V.1
Cheong, J.2
Ciapurin, N.3
McDermitt, D.J.4
Tumbar, T.5
-
19
-
-
78650963929
-
Dynamics between stem cells, niche, and progeny in the hair follicle
-
Hsu Y-C, Pasolli HA, Fuchs E (2011) Dynamics between stem cells, niche, and progeny in the hair follicle. Cell 144(1):92-105.
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 92-105
-
-
Hsu, Y.-C.1
Pasolli, H.A.2
Fuchs, E.3
-
20
-
-
38349098468
-
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
-
Plikus MV, et al. (2008) Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature 451(7176):340-344.
-
(2008)
Nature
, vol.451
, Issue.7176
, pp. 340-344
-
-
Plikus, M.V.1
-
21
-
-
80052293095
-
Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling
-
Festa E, et al. (2011) Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell 146(5):761-771.
-
(2011)
Cell
, vol.146
, Issue.5
, pp. 761-771
-
-
Festa, E.1
-
22
-
-
38649106497
-
NFATc1 balances quiescence and proliferation of skin stem cells
-
Horsley V, Aliprantis AO, Polak L, Glimcher LH, Fuchs E (2008) NFATc1 balances quiescence and proliferation of skin stem cells. Cell 132(2):299-310.
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 299-310
-
-
Horsley, V.1
Aliprantis, A.O.2
Polak, L.3
Glimcher, L.H.4
Fuchs, E.5
-
23
-
-
80052298366
-
Genome-Wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage
-
Lien W-H, et al. (2011) Genome-Wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell 9(3):219-232.
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 219-232
-
-
Lien, W.-H.1
-
24
-
-
0034934515
-
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages
-
Müller-Röver S, et al. (2001) A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol 117(1):3-15.
-
(2001)
J Invest Dermatol
, vol.117
, Issue.1
, pp. 3-15
-
-
Müller-Röver, S.1
-
25
-
-
79955542010
-
Self-Organizing and stochastic behaviors during the regeneration of hair stem cells
-
Plikus MV, et al. (2011) Self-Organizing and stochastic behaviors during the regeneration of hair stem cells. Science 332(6029):586-589.
-
(2011)
Science
, vol.332
, Issue.6029
, pp. 586-589
-
-
Plikus, M.V.1
-
26
-
-
0001634321
-
The growth of hair follicles in waves
-
Chase HB, Eaton GJ (1959) The growth of hair follicles in waves. Ann N Y Acad Sci 83:365-368.
-
(1959)
Ann N y Acad Sci
, vol.83
, pp. 365-368
-
-
Chase, H.B.1
Eaton, G.J.2
-
27
-
-
58949102946
-
A two-Step mechanism for stem cell activation during hair regeneration
-
Greco V, et al. (2009) A two-Step mechanism for stem cell activation during hair regeneration. Cell Stem Cell 4(2):155-169.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.2
, pp. 155-169
-
-
Greco, V.1
-
28
-
-
40549103466
-
Epidermal stem cells are retained in vivo throughout skin aging
-
Giangreco A, Qin M, Pintar JE, Watt FM (2008) Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell 7(2):250-259.
-
(2008)
Aging Cell
, vol.7
, Issue.2
, pp. 250-259
-
-
Giangreco, A.1
Qin, M.2
Pintar, J.E.3
Watt, F.M.4
-
29
-
-
84867208183
-
Age-Associated inflammation inhibits epidermal stem cell function
-
Doles J, Storer M, Cozzuto L, Roma G, Keyes WM (2012) Age-Associated inflammation inhibits epidermal stem cell function. Genes Dev 26(19):2144-2153.
-
(2012)
Genes Dev
, vol.26
, Issue.19
, pp. 2144-2153
-
-
Doles, J.1
Storer, M.2
Cozzuto, L.3
Roma, G.4
Keyes, W.M.5
-
30
-
-
17044364797
-
Melanocyte stem cell maintenance and hair graying
-
Steingrímsson E, Copeland NG, Jenkins NA (2005) Melanocyte stem cell maintenance and hair graying. Cell 121(1):9-12.
-
(2005)
Cell
, vol.121
, Issue.1
, pp. 9-12
-
-
Steingrímsson, E.1
Copeland, N.G.2
Jenkins, N.A.3
-
31
-
-
40349085766
-
The longest telomeres: A general signature of adult stem cell compartments
-
Flores I, et al. (2008) The longest telomeres: A general signature of adult stem cell compartments. Genes Dev 22(5):654-667.
-
(2008)
Genes Dev
, vol.22
, Issue.5
, pp. 654-667
-
-
Flores, I.1
-
32
-
-
0011478490
-
Three clonal types of keratinocyte with different capacities for multiplication
-
Barrandon Y, Green H (1987) Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci USA 84(8):2302-2306.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.8
, pp. 2302-2306
-
-
Barrandon, Y.1
Green, H.2
-
33
-
-
14344264665
-
Parabiosis between old and young rats
-
McCay CM, Pope F, Lunsford W, Sperling G, Sambhavaphol P (1957) Parabiosis between old and young rats. Gerontologia 1(1):7-17.
-
(1957)
Gerontologia
, vol.1
, Issue.1
, pp. 7-17
-
-
McCay, C.M.1
Pope, F.2
Lunsford, W.3
Sperling, G.4
Sambhavaphol, P.5
-
34
-
-
84856090875
-
Aging, rejuvenation, and epigenetic reprogramming: Resetting the aging clock
-
Rando TA, Chang HY (2012) Aging, rejuvenation, and epigenetic reprogramming: Resetting the aging clock. Cell 148(1-2):46-57.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 46-57
-
-
Rando, T.A.1
Chang, H.Y.2
-
35
-
-
84877816844
-
Heterochronic parabiosis: Historical perspective and methodological considerations for studies of aging and longevity
-
Conboy MJ, Conboy IM, Rando TA (2013) Heterochronic parabiosis: Historical perspective and methodological considerations for studies of aging and longevity. Aging Cell 12(3):525-530.
-
(2013)
Aging Cell
, vol.12
, Issue.3
, pp. 525-530
-
-
Conboy, M.J.1
Conboy, I.M.2
Rando, T.A.3
-
36
-
-
33749171885
-
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky AV, et al. (2006) Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443(7110):448-452.
-
(2006)
Nature
, vol.443
, Issue.7110
, pp. 448-452
-
-
Molofsky, A.V.1
-
37
-
-
1342289563
-
Bmi1, stem cells, and senescence regulation
-
Park I-K, Morrison SJ, Clarke MF (2004) Bmi1, stem cells, and senescence regulation. J Clin Invest 113(2):175-179.
-
(2004)
J Clin Invest
, vol.113
, Issue.2
, pp. 175-179
-
-
Park, I.-K.1
Morrison, S.J.2
Clarke, M.F.3
-
38
-
-
0032849010
-
Affinity-Driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
-
Aramburu J, et al. (1999) Affinity-Driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science 285(5436):2129-2133.
-
(1999)
Science
, vol.285
, Issue.5436
, pp. 2129-2133
-
-
Aramburu, J.1
-
39
-
-
0030973579
-
Transcription factors of the NFAT family: Regulation and function
-
Rao A, Luo C, Hogan PG (1997) Transcription factors of the NFAT family: Regulation and function. Annu Rev Immunol 15:707-747.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
40
-
-
0036234543
-
NFAT signaling: Choreographing the social lives of cells
-
Crabtree GR, Olson EN (2002) NFAT signaling: Choreographing the social lives of cells. Cell 109(Suppl):S67-S79.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
, pp. 67-79
-
-
Crabtree, G.R.1
Olson, E.N.2
-
41
-
-
84859885816
-
Differential gene and transcript expression analysis of RNAseq experiments with TopHat and Cufflinks
-
Trapnell C, et al. (2012) Differential gene and transcript expression analysis of RNAseq experiments with TopHat and Cufflinks. Nat Protoc 7(3):562-578.
-
(2012)
Nat Protoc
, vol.7
, Issue.3
, pp. 562-578
-
-
Trapnell, C.1
-
42
-
-
84860508493
-
An RNA interference screen uncovers a new molecule in stem cell self-Renewal and long-Term regeneration
-
Chen T, et al. (2012) An RNA interference screen uncovers a new molecule in stem cell self-Renewal and long-Term regeneration. Nature 485(7396):104-108.
-
(2012)
Nature
, vol.485
, Issue.7396
, pp. 104-108
-
-
Chen, T.1
-
43
-
-
43249083269
-
Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells
-
Waghmare SK, et al. (2008) Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells. EMBO J 27(9):1309-1320.
-
(2008)
EMBO J
, vol.27
, Issue.9
, pp. 1309-1320
-
-
Waghmare, S.K.1
-
44
-
-
0020403099
-
Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure
-
Harrison DE, Astle CM (1982) Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure. J Exp Med 156(6):1767-1779.
-
(1982)
J Exp Med
, vol.156
, Issue.6
, pp. 1767-1779
-
-
Harrison, D.E.1
Astle, C.M.2
-
45
-
-
84855486150
-
Paracrine tgf-Â signaling counterbalances BMP-Mediated repression in hair follicle stem cell activation
-
Oshimori N, Fuchs E (2012) Paracrine TGF-Â signaling counterbalances BMP-Mediated repression in hair follicle stem cell activation. Cell Stem Cell 10(1):63-75.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.1
, pp. 63-75
-
-
Oshimori, N.1
Fuchs, E.2
-
46
-
-
0035110666
-
Control of hair growth and follicle size by VEGFmediated angiogenesis
-
Yano K, Brown LF, Detmar M (2001) Control of hair growth and follicle size by VEGFmediated angiogenesis. J Clin Invest 107(4):409-417.
-
(2001)
J Clin Invest
, vol.107
, Issue.4
, pp. 409-417
-
-
Yano, K.1
Brown, L.F.2
Detmar, M.3
-
47
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell C, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28(5):511-515.
-
(2010)
Nat Biotechnol
, vol.28
, Issue.5
, pp. 511-515
-
-
Trapnell, C.1
-
48
-
-
59749096851
-
Isolation and culture of epithelial stem cells
-
Nowak JA, Fuchs E (2009) Isolation and culture of epithelial stem cells. Methods Mol Biol 482:215-232.
-
(2009)
Methods Mol Biol
, vol.482
, pp. 215-232
-
-
Nowak, J.A.1
Fuchs, E.2
-
49
-
-
84874674052
-
NFIB is a governor of epithelial-Melanocyte stem cell behaviour in a shared niche
-
Chang C-Y, et al. (2013) NFIB is a governor of epithelial-Melanocyte stem cell behaviour in a shared niche. Nature 495(7439):98-102.
-
(2013)
Nature
, vol.495
, Issue.7439
, pp. 98-102
-
-
Chang, C.-Y.1
-
50
-
-
0242460440
-
Manipulation of stem cell proliferation and lineage commitment: Visualisation of label-Retaining cells in wholemounts of mouse epidermis
-
Braun KM, et al. (2003) Manipulation of stem cell proliferation and lineage commitment: Visualisation of label-Retaining cells in wholemounts of mouse epidermis. Development 130(21):5241-5255.
-
(2003)
Development
, vol.130
, Issue.21
, pp. 5241-5255
-
-
Braun, K.M.1
-
51
-
-
62349130698
-
Ultrafast and memory-Efficient alignment of short DNA sequences to the human genome
-
Langmead B, Trapnell C, Pop M, Salzberg SL (2009) Ultrafast and memory-Efficient alignment of short DNA sequences to the human genome. Genome Biol 10(3):R25.
-
(2009)
Genome Biol
, vol.10
, Issue.3
, pp. 25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
52
-
-
57449100870
-
Design and analysis of ChIP-Seq experiments for DNA-Binding proteins
-
Kharchenko PV, Tolstorukov MY, Park PJ (2008) Design and analysis of ChIP-Seq experiments for DNA-Binding proteins. Nat Biotechnol 26(12):1351-1359.
-
(2008)
Nat Biotechnol
, vol.26
, Issue.12
, pp. 1351-1359
-
-
Kharchenko, P.V.1
Tolstorukov, M.Y.2
Park, P.J.3
-
53
-
-
67849122320
-
Meme suite: Tools for motif discovery and searching
-
(Web Server issue):W202-8
-
Bailey TL, et al. (2009) MEME SUITE: Tools for motif discovery and searching. Nucleic Acids Res 37(Web Server issue):W202-8.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Bailey, T.L.1
|