Herbal remedies for combating irradiation: A green antiirradiation approach

Asian Pacific Journal of Cancer Prevention

Volumn 14, Issue 10, 2013, Pages 5553-5565

  Lachumy, Subramanion Jothy ^a   Oon, Chern Ein ^a   Deivanai, Subramanian ^b   Saravanan, Dharmaraj ^c   Vijayarathna, Soundararajan ^a   Choong, Yee Siew ^a   Yeng, Chen ^d   Latha, Lachimanan Yoga ^a   Sasidharan, Sreenivasan ^a  

^a INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^b AIMST UNIVERSITY   (Malaysia)

^c UNIVERSITI SULTAN ZAINAL ABIDIN   (Malaysia)

^d UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Green approach; Ionizing radiation; Medicinal plant; Radioprotective

Indexed keywords

RADIOPROTECTIVE AGENT;

ANIMAL; HERBAL MEDICINE; HUMAN; MEDICINAL PLANT; PHYTOTHERAPY; PROCEDURES; TRADITIONAL MEDICINE;

ANIMALS; HERBAL MEDICINE; HUMANS; MEDICINE, TRADITIONAL; PHYTOTHERAPY; PLANTS, MEDICINAL; RADIATION-PROTECTIVE AGENTS;

EID: 84890459782     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.10.5553     Document Type: Review

References (116)

1. Afaq F, Adhami VM, Ahmad N (2003). Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicol Appl Pharmacol, 186, 28-37.
2. Anonymous (2013a). A-bombed Ginkgo trees in Hiroshima, Japan+documentary film.
3. Anonymous (2013b). Laughter Yoga. Medicinal value of Tulsi.
4. Apak R, Guclu K, Demirata B, et al (2007). Comparative evaluation of various total antioxidant capacity assays applied to phenolic compounds with the CUPRAC assay. Molecules, 12, 1496-547.
5. Arora R, Gupta D, Chawla R, et al (2005). Radioprotection by plant products: present status and future prospects. Phytother Res, 19, 1.
6. Ashawat MS, Saraf S, Saraf S (2006). Cosmetic potentiality of plant extracts and natural oils. Biosci Biotechnol Res Asia, 3, 181-8.
7. Attaguile G, Russo A, Campisi A, et al (2000). Antioxidant activity and protective effect on DNA cleavage of extracts from cistus incanus L and cistus monspeliensis L. Cell Biol Toxicol, 16, 83-90.
8. Azad MB, Chen Y, Gibson SB (2009). Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxid Redox Signal, 11, 777-90.
9. Aziz MH, Shaw SR, Wu J, Longley BJ, Ahmad N (2005). Chemoprevention of skin cancer by grape constituent resveratol: relevance to human disease? FASEB, 19, 1.
10. Bajpai M, Parade A, Tiwari SK, Prashad D (2005). Phenolic content and antioxidant activity of some food and medicinal plants. Int J Food Sci Nut, 4, 287-91.
11. Bertho JM, Roy L, Souidi M, et al., (2008). New biological indicators to evaluate and monitor radiation-induced damage: an accident case report. Radiat Res, 169, 543-0.
12. Biaglow JE (1987). The effects of ionizing radiation on mammalian cells. In: Farhataziz Rodgers Maj. Ed. Radiation chemistry: principles and applications. New York: VCH, 527-63.
13. Brown PE (1967). Mechanism of action of aminothiol radioprotectors. Nature, 213, 363-4.
14. Burrow CJ, Muller JG (1998). Oxidative nucleobase modifications leading to strand scission. Cancer Res, 98, 1109-51.
15. Campos PMBGM, Gianeti MD, Kanashiro A, Lucisano VYM, Gaspar LR (2006). In vitro antioxidant and in vivo photoprotective effects of an association of bioflavonoids with liposoluble vitamins. Photochem Photobiol, 82, 683-8.
16. Casarett AP (1968). Radiation Biology. Prentice-Hall, Englewood Cliffs, NJ, pp. 158-89.
17. Chauhan LKS, Saxena PN, Gupta SK (1999). Cytogenetic effects of cypermethrin and fenvalerate on the root meristem cells of Allium cepa. Environ Exp Bot, 42, 181-9.
18. Chipuk JE, Kuwana T, Bouchier-Hayes L, et al (2004). Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science, 303, 1010-4.
19. Christopher HB, Kapoor MB (1988). The cytogenetic effects of sodium salicylate on the root meristem cells of Allium sativa L. Cytologia, 54, 203-9.
20. Cimino F, Cristani M, Saija A, Bonina FP, Virgili F (2007). Protective effects of a red orange extract on UVB-induced damage in human keratinocytes. Biofactors, 30, 129-38.
21. Collins AR (2004). The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol, 26, 249-61.
22. Cragg GM, Newman DJ, Snader KM (1997). Natural products in drug discovery and development. J Nat Prod, 60, 52-60.
23. Edinger AL, Thompson CB (2004). Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol, 16, 663-9.
24. Erden Inal M, Kahraman A, Koken T (2001). Beneficial effects of quercetin on oxidative stress induced by ultraviolet A. Clin Exp Dermatol, 26, 536-9.
25. Fenech M (2000). The in vitro micronucleus test technique. Mut Res, 455, 81-95.
26. Fernandes TCC, Mazzeo DEC, Marin-Morales MA (2007). Mechanism of micronuclei formation in polyploidizated cells of Allium cepa exposed to trifluralin herbicide. Pestic Biochem Phys, 88, 252-9.
27. Fguyer S, Afaq F, Mukhtar H (2003). Photochemoprevention of skin cancer by botanical agents. Photodermatol Photoimmunol Photomed, 19, 56-72.
28. Frankel EN, Huang SW, Aeschbach R, Prior E (1996). Antioxidant activity of a rosemary extract and its constituents, carnosic acid, carnosol and rosmarinic acid, in bulk oil and oil-inwater emulsion. J Agri Food Chem, 44, 131-5.
29. Garcia Bores AM, Avila JG (2008). Natural products: Molecular mechanisms in the photo chemoprevention of skin cancer. Rev Latinoamer Quim, 36, 83-102.
30. Ghavami S, Eshragi M, Ande SR, et al (2010). S100A8/A9 induces autophagy and apoptosis via ROS-mediated crosstalk between mitochondria and lysosomes that involves BNIP3. Cell Res, 20, 314-31.
31. Grant WF (1994). The present status of higher plant bioassays for the detection of environmental mutagens. Mutat Res, 310, 175-85.
32. Griffiths CEM, Maddin S, Weidow O, et al (2005). Treatment of photoaged skin with a cream containing 0.05% isotretinoin and sunscreens. J Dermatol Treat, 16, 79-86.
33. Griffiths NM, Dublineau I, Francois A, Ksas B (1999). Radiationinduced colonic injury: decreased ?uid absorption and effects of granisetron a 5-HT3 receptor inhibitor. Adv Radiat Biol Peace, 2, 1-10.
34. Gupta ML, Agarwala PK, Prem KI, et al (2008). Modulation of gamma radiation-inflicted damage in swiss albino mice by an alcoholic fraction of Podophyllum hexandrum rhizome. J Medicinal Food, 11, 486-92.
35. Handa SS (2008). An overview of Extraction Techniques for Medicinal and Aromatic Plants. In: Extraction Technologies for Medicinal and Aromatic Plants, Handa, S.S.; Khanuja, S.P.S.; Longo, G.; Rakesh, D.D; (Eds.), pp 21-54.
36. Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet, 342, 1007-11.
37. Higdon J (2007). An evidence-based approach to dietaryphytochemicals. New York: Thieme Medical.
38. Huang D, Ou B, Prior RL (2005). Review: the chemistry behind antioxidant capacity assays. J Agric Food Chem, 53, 1841-56.
39. Jagetia GC (2007). Radioprotective potential of plants and herbs against the effects of ionizing radiation. J Clin Biochem Nutr, 40, 74-81.
40. Jagetia GC, Venkatesha VA (2005). Effect of mangiferin on radiation-induced micronucleus formation in cultured human peripheral blood lymphocytes. Environ Mol Mutagen, 46, 12-21.
41. Jothy SL, Zakaria Z, Chen Y, et al (2011). Acute oral toxicity of methanolic seed extract of cassia fistula in mice. Molecules, 16, 5268-82.
42. Kaplan EL, Meier P (1958). Nonparametric estimation from in-complete observations. J Amer Stat Assoc, 53, 457-81.
43. Kapoor VK, Dureja J, Chadha R (2009). Herbals in the control of ageing. Drug Discov Today, 14, 992-8.
44. Katiyar SK, Afaq F, Perez A, Mukhtar H (2001). Green tea polyphenols (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiationinduced oxidative stress. Carcinogenesis, 22, 287-94.
45. Katiyar SK, Ahmad N, Mukhtar H (2000). Green tea and skin. Arch Dermatol, 136, 989-94.
46. Katiyar SK, Elmets CA (2001). Green tea polyphenolic antioxidant and skin photoprotection- review. Int J Oncol, 18, 1307-13.
47. Katiyar SK (2009). Treatmetn of silymarin, a plant flavonoid prevent ultra violet light induced suppression and oxidative stress in mouse skin. Int J Oncol, 21, 1213-22.
48. Kaur CD, Saraf S (2011b). Photoprotective herbal extract loaded nanovesicular creams inhibiting ultra violet radiations induced photoaging. Int J Drug Delivery, 3, 699-711.
49. Korac RR, Khambholja KM (2011). Potential herbs in skin protection from ultra violet radiation. Pharmacogn Rev, 5, 164-73.
50. Kumar S, Maheshwari KK, Singh V (2009). Protective effects of Punica granatum seeds extract against aging and scopolamine induced cognitive impairments in mice. Afr J Trad CAM, 6, 49-56.
51. Lata M, Prasad J, Singh S, et al (2009). Whole body protection against lethal ionizing radiation in mice by REC-2001: a semi-purified fraction of Podophyllum hexandrum. Phytomed, 16, 47-55.
52. Lee TK, Johnke RM, Allison RR, O'Brien KF, Dobbs LJ Jr (2005). Radioprotective potential of ginseng. Mutagenesis, 20, 237-43.
53. Leme DM, Marin-Morales MA (2009). Allium cepa test in environmental monitoring: a review on its application. Muta Res, 682, 71-81.
54. Lewis SM (2006). Reference ranges and normal values, in Dacie and Lewis-Practical Haematology, Lewis, S.M., Bain, B.J., Bates, I., Eds., Churchill Levingstone: New York, NY, USA, 3th edition, pp.11-24.
55. Li YH, Wu Y, Wei HC, et al (2009). Protective effects of green tea extracts on photo aging and photommunosuppression. Skin Res Technol, 15, 338-45.
56. Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996). Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell, 86, 147-57.
57. Londhe JS, Devasagayam TP, Foo LY, Ghaskadbi SS (2009). Radioprotective properties of polyphenols from Phyllanthus amarus Linn. J Radiat Res, 50, 303-9.
58. Mantena SK, Katiyar SK (2006). Grape seed proanthocyanidins inhibit UV-radiation induced oxidative stress and activation of MAPK and NF-kappa B signaling human epidermal kerationcytes. Free Radic Biol Med, 40, 1603-14.
59. Maurya DK, Salvi VP, Krishnan Nair CK (2004). Radioprotection of normal tissues in tumor-bearing mice by troxerutin. J radiat res, 45, 221-8.
60. McGuire K (2012). Earth Fairy's Dream. Holy Basil, Ocimum sanctum.
61. Miller R, Miller S (2003). Tulsi Queen of Herbs. India's Holy Basil.
62. Nichols JA, Katiyar SK (2010). Skin protection by natural phenols: anti-inflammatory, antioxidant and DNA repair mechanism. Arch Dermatol Res, 302, 71.
63. Nunia V, Goyal PK (2004). Prevention of gamma radiation induced anaemia in mice by diltiazem. J Radiat Res, 45, 11-7.
64. OECD (2001). OECD Guidelines for Acute Toxicity of Chemicals; Organisation for Economic Co-operation and Development: Paris, France, No. 420.
65. Olive PL, Banáth JP (2006). The comet assay: a method to measure DNA damage in individual cells. Nat Protoc, 1, 23-9.
66. Olive PL, Banáth JP, Durand RE (1990). Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat Res, 122, 86-94.
67. Olive PL, Johnston PJ (1997). DNA damage from oxidants: influence of lesion complexity and chromatin organization. Oncol Res, 9, 287-94.
68. Ostling O, Johanson KJ (1984). Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem Biophys Res Commun, 123, 291-8.
69. Ozben T (2007). Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci, 96, 2181-96.
70. Pahadiya S, Sharma J (2003). Alteration of lethal effects of gamma rays in Swiss albino mice by Tinospora cordifolia. Phytother Res, 17, 522.
71. Patt HM, Tyree EB, Straube RL, Smith DE (1949). Cysteine protection against X-irradiation. Science, 110, 213-4.
72. Peter OB, Catalina CP, Hernan S (2006). Boldine and its antioxidant or health promoting properties. Chemico- Biological Interactions, 159, 1-17.
73. Pham-Huy LA, He H, Pham-Huyc C (2008). Free radicals, antioxidanta in disease and health. Int J Biomed Sci, 4, 89-96.
74. Pickstone W (2010). Mother Nature's Natural Healing Gifts! A-Z Of Herbs! Wayne Pickstone.
75. Potten CS (1990). A comprehensive study of the radiobiological response of the murine (BDF1) small intestine. Int J Radiat Biol, 58, 925-73.
76. Prasad KN (1982). Acute radiation syndromes. In Pizzarelo, D.L. Ed. Radiation biology, Boca Raton: CRC, 205-35.
77. Prasad KN (1999). Handbook of Radiobiology. CRC Press: Boca Raton, FL, 344.
78. Qi L, Liu CY, Wu WQ, Gu ZL, Guo CY (2011). Protective effect of flavonoids from Astragalus complanatus on radiation induced damages in mice. Fitoterapia, 82, 383-92.
79. Rajkumar V, Guha G, Ashok Kumar R, Mathew L (2010). Evaluation of antioxidant activities of bergenia ciliata rhizome. Rec Nat Prod, 4, 38-48.
80. Rank J, Nielsen MH (1997). Allium cepa anaphase-telophase root tip chromosome aberration assay on N-methyl-Nnitrosourea, maleic hydrazide, sodium azide, and ethyl methanesulfonate. Muta Res, 390, 121-7.
81. Rao BSS, Devi PU (2005). Response of S 180 murine tumor to bleomycin in combination with radiation and hyperthermia using micronucleus assay: a multimodality approach for therapeutic augmentation. Indian J Exp Biol, 43, 596-600.
82. Ravichandran G, Bharadwaj VS, Kolhapure SA (2005). Evaluation of the efficacy and safety of "Anti-Wrinkle cream" in the treatment of facial skin wrinkles: a prospective, open, phase III clinical trial. The Antiseptic, 102, 65-70.
83. Russo A, Cardile V, Caggia S, et al (2011). Boldo prevents UV light and nitric oxide-mediated plasmid DNA damage and reduces the expression of Hsp70 protein in melanoma cancer cells. J Pharm Pharmacol, 63, 1219-29.
84. Samarth RM, Goyal PK, Kumar A (2001). Radioprotective effects of Mentha piperita. J Med Aromat Plant Sci, 22, 91-7.
85. Sanghmitra S, Gupta M, Gupta V, et al (2009). Podophyllum hexandrum- mediated survival protection and restoration of other cellular injuries in lethally irradiated mice. eCAM, 16, 47-55.
86. Saraf S, Kaur CD (2010). Phytoconstituents as photoprotective novel cosmetic formulations. Pharmacognosy Review, 4, 1-11.
87. Sasidharan S, Yoga Latha L, Ping KY, Jothy Lachumy S (2012). Screening Methods in the Study of Fungicidal Property of Medicinal Plants. In: Fungicides for Plant and Animal Diseases, Dharumadurai Dhanasekaran, (Ed.), 107-118.
88. Sharangi AB (2009). Medicinal and therapeutic potentialities of tea (Camellia sinensis L.)-A review. Food Res Inl, 42, 529-35.
89. Shukla SK, Gupta ML (2010). Approach towards development of a radioprotector using herbal source against lethal irradiation. Int Res J Plant Sci, 1, 118-25.
90. Silveira JPS, Seito LN, Eberlin S, et al (2013). Photoprotective and antioxidant effects of Rhubarb: inhibitory action on tyrosinase and tyrosine kinase activities and TNF-a, IL- 1a and a-MSH production in human melanocytes. BMC Complement Altern Med, 13, 49.
91. Singh NP, McCoy MT, Tice RR, Schneider EL (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res, 175, 184-91.
92. Singh U, Kunwar A, Srinivasan R, Nanjan MJ, Priyadarsini KI (2009). Differential free radical scavenging activity and radioprotection of Caesalpinia digyna extracts and its active constituent. J Radiat Res, 50, 425-33.
93. Song JH, Bae EY, Choi G, et al (2013). Protective effect of mango (Mangifera indica L.) against UVB-induced skin aging in hairless mice. Photodermatol Photoimmunol Photomed, 29, 84-9.
94. Speit G, Hartmann A (2005). The comet assay: a sensitive genotoxicity test for the detection of DNA damage. Methods Mol Biol, 291, 85-95.
95. Spotheim-Maurizot M, Franchet J, Sabattier R, Charlier M (1991). DNA radiolysis by fast neutrons: II. Oxygen, thiols and ionic strength effects. Int J Radiat Biol, 59, 1313-24.
96. Susin SA, Lorenzo HK, Zamzami N, et al (1999). Molecular characterization of mitochondrial apoptosis-inducing factor. Nature, 397, 441-6.
97. Svobova A, Psotova J, Walterova D (2003). Natural phenolics in the prevention of UV induced skin damage. A review. Biomed Papers, 147, 137-45.
98. Szumiel I (2011). Autophagy, reactive oxygen species and the fate of mammalian cells. Free Radic Res, 45, 253-65.
99. Till JE, McCulloch EA (1961). A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res, 14, 213-22.
100. Tiwari A (2001). Imbalance in antioxidant defense and human diseases: multiple approach of natural antioxidant therapy. Current Science, 81, 1179-87.
101. Tsoyi K, Hyung BP, Young MK, et al (2008). Protective effect of anthocyanins from black soybean seed coats on UVBinduced apoptotic cell death in vitro and in vivo. J Agric Food Chem, 56, 10600-5.
102. Tsujimoto Y (2003). Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol, 195, 158-67.
103. USNRC Technical Training Center (2013). Biological Effects of Radiation. Reactor concepts manual.
104. Vaid M, Katiyar SK (2010). Molecular mechanisms of inhibition of phtocarcinogenesis by silymarin, a phytochemical from milk thistle (Silybum marianum L. Gaerth). Int J Oncol, 36, 1053-60.
105. Varanda EA, Tavares DC (1998). Radioprotection: mechanisms and radioprotective agents including honeybee venom. J Venom Anim Toxins, 4, 5-21.
106. Vigneulle RM, Rao S, Fasano A, MacVittie T (2002). Structural and functional alterations of the gastrointestinal tract following radiation induced injury in the rhesus monkey. Digestive Dis Sci, 47, 1480-91.
107. Vile GF (1997). Active oxygen species mediate the solar ultraviolet radiation dependent increase in the tumour suppressor protein p53 in human skin fibroblasts. FEBS Lett, 412, 70-4.
108. Villunger A, Michalak EM, Coultas L, et al (2003). p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science, 302, 1036-8.
109. Visvardis EE, Tassiou AM, Piperakis SM (1997). Study of DNA damage induction and repair capacity of fresh and cryopreserved lymphocytes exposed to H2O2 and gamma irradiation with the alkaline comet assay. Mutat Res, 383, 71-80.
110. Von Sonntag C (1987). The Chemical Basis of Radiation Biology, Taylor & Francis, London, pp. 65-84.
111. Walum E, Nilsson M, Clemedson C, Ekwall B (1995). The MEIC program and its implications for the prediction of acute human systemic toxicity. In Alternative Methods in Toxicology and theLife Sciences; Goldberg, A.M., van Zutphen, L.F.M., Eds.; Mary Ann Liebert: New York, NY, USA, Vol.11, pp. 275-82.
112. West DP, Zhu YF (2003). Evaluation of Aloe vera gel gloves in the treatment of dry skin associated with occupational exposure. Am J Infect Control, 31, 40-2.
113. Widyarini S, Spinks N, Husband AJ, Reeve VE (2001). Isoflavonoid compounds from red clover (Trifolium pratense) protect from inflammation and immune suppression induced by UV radiation. Photochem Photobiol, 74, 465-70.
114. Wochna A, Niemczyk E, Kurono C, et al (2007). A possible role of oxidative stress in the switch mechanism of the cell death mode from apoptosis to necrosis-studies on rho0 cells. Mitochondrion, 7, 119-24.
115. Wu WS (2006). The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev, 25, 695-705.0
116. Yuhas JM, Storer JB (1969). Chemoprotection against three modes of radiation death in the mouse. In. J Radiat Biol Relat Stud Phys Chem Med, 15, 233-7.