Isoflavonoid compounds from red clover (Trifolium pratense) protect from inflammation and immune suppression induced by UV radiation

Photochemistry and Photobiology

Volumn 74, Issue 3, 2001, Pages 465-470

  Widyarini, Sitarina ^a   Spinks, Nicole ^b   Husband, Alan J ^b   Reeve, Vivienne E ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Novogen Limited   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHANIN A; COSMETIC; DAIDZEIN; DEHYDROEQUOL; EQUOL; FORMONONETIN; GENISTEIN; ISOEQUOL; ISOFLAVONE; ISOFLAVONOID; OXIDIZING AGENT; UNCLASSIFIED DRUG; UROCANIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CLOVER; CONCENTRATION RESPONSE; CONTACT ALLERGY; CONTROLLED STUDY; EDEMA; FEMALE; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; LOTION; MOUSE; NONHUMAN; NUDE MOUSE; RADIATION DOSE; RADIATION EXPOSURE; RADIATION PROTECTION; SOLAR RADIATION; ULTRAVIOLET RADIATION;

ANIMALS; FEMALE; IMMUNE TOLERANCE; INFLAMMATION; ISOFLAVONES; MICE; MICE, INBRED HRS; PHOTOBIOLOGY; ROSALES; SKIN; SUNSCREENING AGENTS; ULTRAVIOLET RAYS;

ANIMALIA; MUS MUSCULUS; TRIFOLIUM; TRIFOLIUM PRATENSE; UCA;

EID: 0035470744     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2001)074<0465:ICFRCT>2.0.CO;2     Document Type: Article

References (43)

1. Adlercreutz, H., T. Fotsis, R. Heikkinen, J. T. Dwyer, M. Woods, B. R. Goldin and S. L. Gorbach (1982) Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Lancet 2, 1295-1299.
2. Axelson, M., J. Sjovall, B. E. Gustafsson and K. D. Setchell (1982) Soya - a dietary source of the non-steroidal oestrogen equol in man and animals. J. Endocrinol. 102, 49-56.
3. Adlercreutz, H., H. Honjo, A. Higashi, T. Fotsis, E. Hamalainen, T. Hasegawa and H. Okada (1991) Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am. J. Clin. Nutr. 54, 1093-1100.
4. Pentland, A. P., M. Mahoney, C. Jacobs and J. Holtzman (1990) Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema. J. Clin. Invest. 86, 556-574.
5. Steenvoorden, D. P. T. and G. M. J. B. van Henegouwen (1997) The use of endogenous antioxidants to improve photoprotection. [Review] J. Photochem. Photobiol. B: Biol. 41, 1-10.
6. Ley, R. D. and V. E. Reeve (1997) Chemoprevention of ultraviolet radiation-induced skin cancer. Environ. Health Perspect. 105S, 981-984.
7. Naylor, M. F. (1997) Erythema, skin cancer and sunscreens. [Editorial Review] Arch. Dermatol. 133, 373-375.
8. Fisher, M. S. and M. L. Kripke (1982) Suppressor T lymphocytes control the development of primary skin cancers in UV-irradiated mice. Science 216, 1133-1134.
9. Reeve, V. E., M. Bosnic, C. Boehm-Wilcox, N. Nishimura and R. D. Ley (1998) Ultraviolet A radiation (320-400nm) protects hairless mice from immunosuppression induced by ultraviolet B radiation (280-320 nm) or cis-urocanic acid. Int. Arch. Allergy Immunol. 115, 316-322.
10. Kripke, M. L. and M. S. Fisher (1976) Immunologic parameters of ultraviolet carcinogenesis. J. Natl. Cancer Inst. 57, 211-215.
11. Kinlen, L. F., A. G. R. Sheil, J. Peto and R. Doll (1979) Collaborative United Kingdom-Australia study of cancer in patients treated with immunosuppressive drugs. Br. J. Med. 11, 1461-1466.
12. O'Dell, B. L., R. T. Jessen, L. E. Becker, R. T. Jackson and E. B. Smith (1980) Diminished immune response in sun-damaged skin. Arch. Dermatol. 116, 559-561.
13. Boyle, J., R. M. MacKie, J. Briggs, B. J. R. Junor and T. C. Aitchison (1984) Cancer, warts and sunshine in renal transplant patients: a case-control study. Lancet 1, 702-705.
14. Yoshikawa, T., V. Rae, W. Bruins-Slot, J. W. Van den Berg, J. R. Taylor and J. W. Streilein (1990) Susceptibility to effects of UV radiation on induction of contact hypersensitivity as a risk factor for skin cancer. J. Invest. Dermatol. 95, 530-536.
15. Norval, M., T. J. Simpson and J. A. Ross (1989) Urocanic acid and immunosuppression. Photochem. Photobiol. 50, 267-271.
16. Noonan, F. P. and E. C. De Fabo (1992) Immunosuppression by ultraviolet radiation: initiation by urocanic acid. Immunol. Today 13, 250-254.
17. Norval, M., N. K. Gibbs and J. Gilmour (1995) The role of urocanic acid in UV-induced immunosuppression: recent advances (1992-1994). Photochem. Photobiol. 62, 209-217.
18. Norval, M., J. W. Gilmour and T. J. Simpson (1990) The effect of histamine receptor antagonists on immunosuppression induced by the cis-isomer of urocanic acid. Photodermatol. Photoimmunol. Photomed. 7, 243-248.
19. 2 production by human keratinocytes: link to indomethacin-inhibitable UVB-induced immunosuppression. Photochem. Photobiol. 61, 303-309.
20. Reeve, V. E., M. Bosnic and E. Rozinova (1993) Carnosine (β-alanylhistidine) protects from the suppression of contact hypersensitivity by ultraviolet B (280-320 nm) radiation or by cis-urocanic acid. Immunology 78, 99-104.
21. Reeve, V. E., M. Bosnic, E. Rozinova and C. Boehm-Wilcox (1993) A garlic extract protects from ultraviolet B (280-320 nm) radiation-induced suppression of contact hypersensitivity. Photochem. Photobiol. 58, 813-817.
22. Katiyar, S. K., C. A. Elmets, R. Agarwal and H. Mukhtar (1995) Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. Photochem. Photobiol. 62, 855-861.
23. Nakamura, T., S. R. Pinnell, D. Darr, I. Kurimoto, S. Itami, K. Yoshikawa and J. W. Streilein (1997) Vitamin C abrogates the deleterious effects of UVB radiation on cutaneous immunity by a mechanism that does not depend on TNF-α. J. Invest. Dermatol. 109, 20-24.
24. Yuen, K. S. and G. M. Halliday (1997) Alpha-tocopherol, an inhibitor of epidermal lipid peroxidation, prevents ultraviolet radiation from suppressing the skin immune system. Photochem. Photobiol. 65, 587-592.
25. Reeve, V. E. and R. M. Tyrrell (1999) Heme oxygenase induction mediates the photoimmunoprotective effect of UVA radiation in the mouse. Proc. Natl. Acad. Sci. USA 96, 9317-9321.
26. Wei, H., L. Wei, R. Bowen, K. Frenkel and S. Barnes (1993) Inhibition of tumor promotion-induced hydrogen peroxide production in vitro and in vivo by genistein. Nutr. Cancer 20, 1-12.
27. Wei, H., R. Bowen, Q. Cai, S. Barnes and Y. Wang (1995) Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc. Soc. Exp. Biol. Med. 208, 124-130.
28. Wei, H. C., Q. Y. Cai and R. O. Rahn (1996) Inhibition of UV light- and Fenton reaction-induced oxidative DNA damage by the soybean isoflavone genistein. Carcinogenesis 17, 73-77.
29. Cai, Q. Y. and H. C. Wei (1996) Effect of dietary genistein on antioxidant enzyme activities in Sencar mice. Nutr. Cancer 25, 1-7.
30. Isoherranen, K., K. Punnonen, C. Jansen and P. Uotila (1999) Ultraviolet irradiation induced cyclo-oxygenase-2 expression in keratinocytes. Br. J. Dermatol. 140, 1017-1022.
31. Wolf, P., C. K. Donawho and M. L. Kripke (1993) Analysis of the protective effect of different sunscreens on ultraviolet radiation-induced local and systemic suppression of contact hypersensitivity and inflammatory responses in mice. J. Invest. Dermatol. 100, 254-259.
32. Geyer, D., M. G. F. Gerrits, A. Renoux and W. Uhl (1999) Pharmacokinetics of Fem7 (R), a once-weekly, transdermal oestrogen replacement system in healthy, postmenopausal women. Gynecol. Obstetr. Invest. 48, 1-6.
33. Franke, A. A., L. J. Custer, C. M. Cerna and K. Narala (1995) Rapid HPLC analysis of dietary phytoestrogens from legumes and from human urine. Proc. Soc. Exp. Biol. Med. 208, 18-26.
34. Ruiz-Larrea, M. B., A. R. Mohan, G. Paganga, N. J. Miller, G. P. Bolwell and C. A. Rice-Evans (1997) Antioxidant activity of phytoestrogenic isoflavones. Free Radic. Res. 26, 63-70.
35. Miller, C. C., P. Hale and A. P. Pentland (1994) Ultraviolet-B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway - evidence for UVB-induced epidermal growth factor receptor activation. J. Biol. Chem. 269, 3529-3533.
36. Palaszynski, E. W., F. P. Noonan and E. C. De Fabo (1992) cis-urocanic acid down-regulates the induction of adenosine 3′5′-cyclic monophosphate by either trans-urocanic acid or histamine in human dermal fibroblasts in vitro. Photochem. Photobiol. 55, 165-171.
37. Koizumi, H., T. Shimizu, H. Nishino and A. Ohkawara (1998) cis-urocanic acid attenuates histamine receptor-mediated activation of adenylate cyclase and increase in intracellular Ca2+. Arch. Dermatol. Res. 290, 264-269.
38. Ruiz-Larrea, M. B., C. Martin, R. Martinez, R. Navarro, M. Lacort and N. J. Miller (2000) Antioxidant activities of estrogens against aqueous and lipophilic radicals; differences between phenol and catechol estrogens. Chem. Phys. Lipids 105, 179-188.
39. Konukoglu, D., O. Serin and H. K. Yelke (2000) Effects of hormone replacement therapy on plasma nitric oxide and total thiol levels in postmenopausal woman. J. Toxicol. Env. Health (Part A) 60, 81-87.
40. Blumel, J. E., C. Castelo-Branco, P. Gonzalez, C. Moyano, M. Iturriaga, L. Videla, A. Sajuan and A. Cano (2000) Transdermal estrogens do not appear to modify the extent of lesional areas of aortic atherosclerosis in ophorectomized rabbits on a cholesterol-rich diet. Atherosclerosis 148, 303-308.
41. Culmsee, C., H. Vedder, A. Ravati, V. Junker, D. Otto, B. Ahlemeyer, J. C. Krieg and J. Krieglstein (1999) Neuroprotection by estrogens in a mouse model of focal cerebral ischemia and in cultured neurons: evidence for a receptor-independent antioxidative mechanism. J. Cerebr. Blood Flow Metab. 19, 1263-1269.
42. Jenkins, D. J., C. W. C. Kendall, M. Garsetti, R. S. Rosenberg-Zand, C. J. Jackson, S. Agarawal, A. V. Rao, E. P. Diamandis, T. Parker, D. Faulkner, V. Vuksan and E. Vidgen (2000) Effect of soy protein foods on low-density lipoprotein oxidation and ex vivo sex hormone receptor activity - a controlled crossover trial. Metab. Clin. Exp. 49, 537-543.
43. Ahmed, N. U., M. Ueda, O. Nikaido, T. Osawa and M. Ichihashi (1999) High levels of 8-hydroxy-2′-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation. Br. J. Dermatol. 140, 226-231.