-
1
-
-
0016750056
-
Pathologic findings and laboratory data in a new strain of obese hypertensive rats
-
1171627 1:STN:280:DyaE2M3it1Ohug%3D%3D
-
Koletsky S (1975) Pathologic findings and laboratory data in a new strain of obese hypertensive rats. Am J Pathol 80:129-142
-
(1975)
Am J Pathol
, vol.80
, pp. 129-142
-
-
Koletsky, S.1
-
2
-
-
0011910306
-
Development of a strain of spontaneously hypertensive rats
-
13939773 10.1253/jcj.27.282 1:STN:280:DyaF387jtFCmsw%3D%3D
-
Okamoto K, Aoki K (1963) Development of a strain of spontaneously hypertensive rats. Jpn Circ J 27:282-293
-
(1963)
Jpn Circ J
, vol.27
, pp. 282-293
-
-
Okamoto, K.1
Aoki, K.2
-
3
-
-
0015891045
-
Obese spontaneously hypertensive rats-a model for study of atherosclerosis
-
4721724 10.1016/0014-4800(73)90040-3 1:STN:280:DyaE3s3islCjsQ%3D%3D
-
Koletsky S (1973) Obese spontaneously hypertensive rats-a model for study of atherosclerosis. Exp Mol Pathol 19:53-60
-
(1973)
Exp Mol Pathol
, vol.19
, pp. 53-60
-
-
Koletsky, S.1
-
4
-
-
0021278994
-
Effect of dietary sucrose on the SHR/N-corpulent rat: A new model for insulin-independent diabetes
-
6369957 1:CAS:528:DyaL2cXktlOmsLY%3D
-
Michaelis OE 4th, Ellwood KC, Judge JM, Schoene NW, Hansen CT (1984) Effect of dietary sucrose on the SHR/N-corpulent rat: a new model for insulin-independent diabetes. Am J Clin Nutr 39:612-618
-
(1984)
Am J Clin Nutr
, vol.39
, pp. 612-618
-
-
Michaelis IV, O.E.1
Ellwood, K.C.2
Judge, J.M.3
Schoene, N.W.4
Hansen, C.T.5
-
5
-
-
0030267744
-
Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat
-
8841178 10.1038/ng1096-130 1:CAS:528:DyaK28XmtVKnt7w%3D
-
Takaya K, Ogawa Y, Hiraoka J, Hosoda K, Yamori Y, Nakao K, Koletsky RJ (1996) Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat. Nat Genet 14:130-131
-
(1996)
Nat Genet
, vol.14
, pp. 130-131
-
-
Takaya, K.1
Ogawa, Y.2
Hiraoka, J.3
Hosoda, K.4
Yamori, Y.5
Nakao, K.6
Koletsky, R.J.7
-
6
-
-
84859427707
-
Diet modification and its influence on metabolic and related pathological alterations in the SHR/NDmcr-cp rat, an animal model of the metabolic syndrome
-
20965707 10.1016/j.etp.2010.09.006 1:CAS:528:DC%2BC38XlsVSjsL4%3D
-
Kawai K, Sakairi T, Harada S, Shinozuka J, Ide M, Sato H, Tanaka M, Toriumi W, Kume E (2012) Diet modification and its influence on metabolic and related pathological alterations in the SHR/NDmcr-cp rat, an animal model of the metabolic syndrome. Exp Toxicol Pathol 64:333-338
-
(2012)
Exp Toxicol Pathol
, vol.64
, pp. 333-338
-
-
Kawai, K.1
Sakairi, T.2
Harada, S.3
Shinozuka, J.4
Ide, M.5
Sato, H.6
Tanaka, M.7
Toriumi, W.8
Kume, E.9
-
7
-
-
33845939627
-
Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp
-
17074368 10.1016/j.lfs.2006.09.041 1:CAS:528:DC%2BD2sXisVOjsg%3D%3D
-
Hussein G, Nakagawa T, Goto H, Shimada Y, Matsumoto K, Sankawa U, Watanabe H (2007) Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp. Life Sci 80:522-529
-
(2007)
Life Sci
, vol.80
, pp. 522-529
-
-
Hussein, G.1
Nakagawa, T.2
Goto, H.3
Shimada, Y.4
Matsumoto, K.5
Sankawa, U.6
Watanabe, H.7
-
8
-
-
0035431018
-
Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
-
11473047 10.2337/diabetes.50.8.1844 1:CAS:528:DC%2BD3MXlslKmsr4%3D
-
Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, McCullough AJ, Natale S, Forlani G, Melchionda N (2001) Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 50:1844-1850
-
(2001)
Diabetes
, vol.50
, pp. 1844-1850
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Bugianesi, E.5
Lenzi, M.6
McCullough, A.J.7
Natale, S.8
Forlani, G.9
Melchionda, N.10
-
9
-
-
33745828301
-
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
-
16492686 10.1152/ajpendo.00644.2005 1:CAS:528:DC%2BD28XovVWgtrc%3D
-
Wei Y, Wang D, Topczewski F, Pagliassotti MJ (2006) Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am J Physiol Endocrinol Metab 291:E275-E281
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Wei, Y.1
Wang, D.2
Topczewski, F.3
Pagliassotti, M.J.4
-
10
-
-
77949655879
-
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis
-
20206402 10.1016/j.jhep.2010.01.003 1:CAS:528:DC%2BC3cXjvFKmsbk%3D
-
Akazawa Y, Cazanave S, Mott JL, Elmi N, Bronk SF, Kohno S, Charlton MR, Gores GJ (2010) Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. J Hepatol 52:586-593
-
(2010)
J Hepatol
, vol.52
, pp. 586-593
-
-
Akazawa, Y.1
Cazanave, S.2
Mott, J.L.3
Elmi, N.4
Bronk, S.F.5
Kohno, S.6
Charlton, M.R.7
Gores, G.J.8
-
11
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: Role of stearoyl-CoA desaturase
-
19119140 10.1074/jbc.M807616200 1:CAS:528:DC%2BD1MXitFSnu78%3D
-
Li ZZ, Berk M, McIntyre TM, Feldstein AE (2009) Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase. J Biol Chem 284:5637-5644
-
(2009)
J Biol Chem
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
Feldstein, A.E.4
-
12
-
-
84856577321
-
Characterization of fatty acid profile in the liver of SHR/NDmcr-cp (cp/cp) rats, a model of the metabolic syndrome
-
22293348 10.1248/bpb.35.184 1:CAS:528:DC%2BC38XlvFOqurk%3D
-
Tanaka S, Yagi Y, Yamazaki T, Mitsumoto A, Kobayashi D, Kudo N, Kawashima Y (2012) Characterization of fatty acid profile in the liver of SHR/NDmcr-cp (cp/cp) rats, a model of the metabolic syndrome. Biol Pharm Bull 35:184-191
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 184-191
-
-
Tanaka, S.1
Yagi, Y.2
Yamazaki, T.3
Mitsumoto, A.4
Kobayashi, D.5
Kudo, N.6
Kawashima, Y.7
-
13
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
13671378 10.1139/o59-099 1:CAS:528:DyaG1MXhtVSgt70%3D
-
Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
14
-
-
0032779170
-
Increase in hepatic content of oleic acid induced by dehydroepiandrosterone in the rat
-
10509745 10.1016/S0006-2952(99)00159-8 1:CAS:528:DyaK1MXltlKlt74%3D
-
Imai K, Koyama M, Kudo N, Shirahata A, Kawashima Y (1999) Increase in hepatic content of oleic acid induced by dehydroepiandrosterone in the rat. Biochem Pharmacol 58:925-933
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 925-933
-
-
Imai, K.1
Koyama, M.2
Kudo, N.3
Shirahata, A.4
Kawashima, Y.5
-
15
-
-
84866019894
-
Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats
-
22975502 10.1248/bpb.35.116 1:CAS:528:DC%2BC38XhslSmsL3P
-
Yamazaki T, Wakabayashi M, Ikeda E, Tanaka S, Sakamoto T, Mitsumoto A, Kudo N, Kawashima Y (2012) Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats. Biol Pharm Bull 35:1509-1515
-
(2012)
Biol Pharm Bull
, vol.35
, pp. 1509-1515
-
-
Yamazaki, T.1
Wakabayashi, M.2
Ikeda, E.3
Tanaka, S.4
Sakamoto, T.5
Mitsumoto, A.6
Kudo, N.7
Kawashima, Y.8
-
16
-
-
0001194552
-
A rapid method for cholesterol determination with a single reagent
-
14185804 1:CAS:528:DyaF2cXkt1Kku7o%3D
-
Zurkowski P (1964) A rapid method for cholesterol determination with a single reagent. Clin Chem 10:451-453
-
(1964)
Clin Chem
, vol.10
, pp. 451-453
-
-
Zurkowski, P.1
-
17
-
-
51649179265
-
Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots
-
17805690 10.1007/BF02668129 1:CAS:528:DyaF28XksFynu7o%3D
-
Rouser G, Siakotos AN, Fleischer S (1966) Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots. Lipids 1:85-86
-
(1966)
Lipids
, vol.1
, pp. 85-86
-
-
Rouser, G.1
Siakotos, A.N.2
Fleischer, S.3
-
18
-
-
33845590381
-
Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet
-
17005996 10.1194/jlr.M600203-JLR200 1:CAS:528:DC%2BD28XhtlSit7fO
-
Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD (2006) Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. J Lipid Res 47:2668-2680
-
(2006)
J Lipid Res
, vol.47
, pp. 2668-2680
-
-
Flowers, M.T.1
Groen, A.K.2
Oler, A.T.3
Keller, M.P.4
Choi, Y.5
Schueler, K.L.6
Richards, O.C.7
Lan, H.8
Miyazaki, M.9
Kuipers, F.10
Kendziorski, C.M.11
Ntambi, J.M.12
Attie, A.D.13
-
19
-
-
0002971810
-
Glycogen: Determination with amyloglucosidase
-
Bergmeyer HU (ed) Academic Press, New York
-
Keppler D, Decker K (1974) Glycogen: determination with amyloglucosidase. In: Bergmeyer HU (ed) Methods of enzymatic analysis, Academic Press, New York
-
(1974)
Methods of Enzymatic Analysis
-
-
Keppler, D.1
Decker, K.2
-
20
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
16931765 10.1126/science.1128294
-
Özcan U, Yilmaz E, Özcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Özcan, U.1
Yilmaz, E.2
Özcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Görgün, C.Z.7
Hotamisligil, G.S.8
-
21
-
-
71849104860
-
Protein measurement with the folin phenol reagent
-
14907713 1:CAS:528:DyaG38XhsVyrsw%3D%3D
-
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275
-
(1951)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
23
-
-
84880570761
-
Up-regulation of stearoyl-CoA desaturase 1 increases liver MUFA content in obese Zucker but not Goto-Kakizaki rats
-
23539346 10.1007/s11745-013-3786-2 1:CAS:528:DC%2BC3sXkslamtbg%3D
-
Karahashi M, Ishii F, Yamazaki T, Imai K, Mitsumoto A, Kawashima Y, Kudo N (2013) Up-regulation of stearoyl-CoA desaturase 1 increases liver MUFA content in obese Zucker but not Goto-Kakizaki rats. Lipids 48:457-467
-
(2013)
Lipids
, vol.48
, pp. 457-467
-
-
Karahashi, M.1
Ishii, F.2
Yamazaki, T.3
Imai, K.4
Mitsumoto, A.5
Kawashima, Y.6
Kudo, N.7
-
24
-
-
0018498892
-
Purification and properties of long-chain acyl-coenzyme-A synthetase from rat liver
-
467438 10.1111/j.1432-1033.1979.tb13173.x 1:CAS:528:DyaE1MXltVCgsrc%3D
-
Tanaka T, Hosaka K, Hoshimaru M, Numa S (1979) Purification and properties of long-chain acyl-coenzyme-A synthetase from rat liver. Eur J Biochem 98:165-172
-
(1979)
Eur J Biochem
, vol.98
, pp. 165-172
-
-
Tanaka, T.1
Hosaka, K.2
Hoshimaru, M.3
Numa, S.4
-
25
-
-
0018136818
-
Selectivity of diacylglycerophosphate synthesis in subcellular fractions of rat liver
-
718160 10.1016/0003-9861(78)90294-1 1:CAS:528:DyaE1MXhslOj
-
Yamada K, Okuyama H (1978) Selectivity of diacylglycerophosphate synthesis in subcellular fractions of rat liver. Arch Biochem Biophys 190:409-420
-
(1978)
Arch Biochem Biophys
, vol.190
, pp. 409-420
-
-
Yamada, K.1
Okuyama, H.2
-
26
-
-
0017065365
-
A highly sensitive assay for microsomal diacylglycerol acyltransferase activity from isolated fat cells
-
5914 10.1016/S0003-2697(76)80009-7 1:CAS:528:DyaE28Xhs1SqtLc%3D
-
Bell RM, Miller Y (1976) A highly sensitive assay for microsomal diacylglycerol acyltransferase activity from isolated fat cells. Anal Biochem 71:436-443
-
(1976)
Anal Biochem
, vol.71
, pp. 436-443
-
-
Bell, R.M.1
Miller, Y.2
-
27
-
-
0028839010
-
Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver
-
7862668 10.1073/pnas.92.4.935 1:CAS:528:DyaK2MXjslehtbY%3D
-
Sheng Z, Otani H, Brown MS, Goldstein JL (1995) Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. Proc Natl Acad Sci USA 92:935-938
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 935-938
-
-
Sheng, Z.1
Otani, H.2
Brown, M.S.3
Goldstein, J.L.4
-
28
-
-
0019313649
-
A new instrument for the rapid preparation of tissue slices
-
6770714 10.1016/0003-2697(80)90284-5 1:STN:280:DyaL3c3hvVWktA%3D%3D
-
Krumdieck CL, dos Santos JE, Ho KJ (1980) A new instrument for the rapid preparation of tissue slices. Anal Biochem 104:118-123
-
(1980)
Anal Biochem
, vol.104
, pp. 118-123
-
-
Krumdieck, C.L.1
Dos Santos, J.E.2
Ho, K.J.3
-
29
-
-
0017172855
-
Dietary control of triglyceride and phospholipid synthesis in rat liver slices
-
1002667 1:CAS:528:DyaE28XlsVWktL0%3D
-
Iritani N, Yamashita S, Numa S (1976) Dietary control of triglyceride and phospholipid synthesis in rat liver slices. J Biochem 80:217-222
-
(1976)
J Biochem
, vol.80
, pp. 217-222
-
-
Iritani, N.1
Yamashita, S.2
Numa, S.3
-
30
-
-
0032962915
-
Fatty acid oxidation affects food intake by altering hepatic energy status
-
10198384 1:STN:280:DyaK1M3hs1ansA%3D%3D
-
Friedman MI, Harris RB, Ji H, Ramirez I, Tordoff MG (1999) Fatty acid oxidation affects food intake by altering hepatic energy status. Am J Physiol 276:R1046-R1053
-
(1999)
Am J Physiol
, vol.276
-
-
Friedman, M.I.1
Harris, R.B.2
Ji, H.3
Ramirez, I.4
Tordoff, M.G.5
-
31
-
-
33846264060
-
Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: The plot thickens
-
17227317 10.1111/j.1464-5491.2007.02025.x 1:STN:280: DC%2BD2s%2FmsVWgsw%3D%3D
-
Targher G (2007) Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: the plot thickens. Diabet Med 24:1-6
-
(2007)
Diabet Med
, vol.24
, pp. 1-6
-
-
Targher, G.1
-
32
-
-
33745107554
-
Mechanisms of disease: Hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance
-
16932311 10.1038/ncpendmet0190 1:CAS:528:DC%2BD28XmtlWlsL0%3D
-
Roden M (2006) Mechanisms of disease: hepatic steatosis in type 2 diabetes-pathogenesis and clinical relevance. Nat Clin Pract Endocrinol Metab 2:335-348
-
(2006)
Nat Clin Pract Endocrinol Metab
, vol.2
, pp. 335-348
-
-
Roden, M.1
-
33
-
-
79952036479
-
Fatty acid regulation of hepatic lipid metabolism
-
21178610 10.1097/MCO.0b013e328342991c 1:CAS:528:DC%2BC3MXhvV2ltrs%3D
-
Jump DB (2011) Fatty acid regulation of hepatic lipid metabolism. Curr Opin Clin Nutr Metab Care 14:115-120
-
(2011)
Curr Opin Clin Nutr Metab Care
, vol.14
, pp. 115-120
-
-
Jump, D.B.1
-
34
-
-
33748744535
-
Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity
-
16790840 10.1194/jlr.M600177-JLR200 1:CAS:528:DC%2BD28Xpt1Gjs7g%3D
-
Wang Y, Botolin D, Xu J, Christian B, Mitchell E, Jayaprakasam B, Nair M, Peters JM, Busik J, Olson LK, Jump DB (2006) Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity. J Lipid Res 47:2028-2041
-
(2006)
J Lipid Res
, vol.47
, pp. 2028-2041
-
-
Wang, Y.1
Botolin, D.2
Xu, J.3
Christian, B.4
Mitchell, E.5
Jayaprakasam, B.6
Nair, M.7
Peters, J.M.8
Busik, J.9
Olson, L.K.10
Jump, D.B.11
-
35
-
-
0033570119
-
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
-
10514488 10.1074/jbc.274.42.30028 1:CAS:528:DyaK1MXmvVajt70%3D
-
Shimomura I, Bashmakov Y, Horton JD (1999) Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. J Biol Chem 274:30028-30032
-
(1999)
J Biol Chem
, vol.274
, pp. 30028-30032
-
-
Shimomura, I.1
Bashmakov, Y.2
Horton, J.D.3
-
36
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
22546860 10.1172/JCI41636 1:CAS:528:DC%2BC38XosFaqsr4%3D
-
Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C (2012) The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans. J Clin Invest 122:2176-2194
-
(2012)
J Clin Invest
, vol.122
, pp. 2176-2194
-
-
Benhamed, F.1
Denechaud, P.D.2
Lemoine, M.3
Robichon, C.4
Moldes, M.5
Bertrand-Michel, J.6
Ratziu, V.7
Serfaty, L.8
Housset, C.9
Capeau, J.10
Girard, J.11
Guillou, H.12
Postic, C.13
-
37
-
-
0035658343
-
Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:lA-cp rat
-
11734577 1:CAS:528:DC%2BD38XhvVSlug%3D%3D
-
Elam MB, Wilcox HG, Cagen LM, Deng X, Raghow R, Kumar P, Heimberg M, Russell JC (2001) Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:lA-cp rat. J Lipid Res 42:2039-2048
-
(2001)
J Lipid Res
, vol.42
, pp. 2039-2048
-
-
Elam, M.B.1
Wilcox, H.G.2
Cagen, L.M.3
Deng, X.4
Raghow, R.5
Kumar, P.6
Heimberg, M.7
Russell, J.C.8
-
38
-
-
0033636780
-
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
-
10949029 1:CAS:528:DC%2BD3cXls1Kls7s%3D
-
Shimomura I, Matsuda M, Hammer RE, Bashmakov Y, Brown MS, Goldstein JL (2000) Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 6:77-86
-
(2000)
Mol Cell
, vol.6
, pp. 77-86
-
-
Shimomura, I.1
Matsuda, M.2
Hammer, R.E.3
Bashmakov, Y.4
Brown, M.S.5
Goldstein, J.L.6
-
39
-
-
74949084316
-
Membrane fatty acid transporters as regulators of lipid metabolism: Implications for metabolic disease
-
20086080 10.1152/physrev.00003.2009 1:CAS:528:DC%2BC3cXitFGgsLY%3D
-
Glatz JF, Luiken JJ, Bonen A (2010) Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol Rev 90:367-417
-
(2010)
Physiol Rev
, vol.90
, pp. 367-417
-
-
Glatz, J.F.1
Luiken, J.J.2
Bonen, A.3
-
40
-
-
0030798890
-
Fatty acid regulation of very low density lipoprotein production
-
9211062 10.1097/00041433-199706000-00004 1:CAS:528:DyaK2sXktlWlsb8%3D
-
Lewis GF (1997) Fatty acid regulation of very low density lipoprotein production. Curr Opin Lipidol 8:146-153
-
(1997)
Curr Opin Lipidol
, vol.8
, pp. 146-153
-
-
Lewis, G.F.1
-
41
-
-
64949105862
-
Sources of hepatic triglyceride accumulation during high-fat feeding in the healthy rat
-
19012281 10.1002/nbm.1327 1:CAS:528:DC%2BD1MXksF2lt7c%3D
-
Delgado TC, Pinheiro D, Caldeira M, Castro MM, Geraldes CF, López-Larrubia P, Cerdán S, Jones JG (2009) Sources of hepatic triglyceride accumulation during high-fat feeding in the healthy rat. NMR Biomed 22:310-317
-
(2009)
NMR Biomed
, vol.22
, pp. 310-317
-
-
Delgado, T.C.1
Pinheiro, D.2
Caldeira, M.3
Castro, M.M.4
Geraldes, C.F.5
López-Larrubia, P.6
Cerdán, S.7
Jones, J.G.8
-
42
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
15864352 1:CAS:528:DC%2BD2MXktFSktLk%3D
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ (2005) Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
43
-
-
0028954296
-
Triacylglycerol biosynthetic enzymes in lean and obese Zucker rats
-
7734438 10.1016/0005-2760(94)00217-M
-
Jamdar SC, Cao WF (1995) Triacylglycerol biosynthetic enzymes in lean and obese Zucker rats. Biochim Biophys Acta 1255:237-243
-
(1995)
Biochim Biophys Acta
, vol.1255
, pp. 237-243
-
-
Jamdar, S.C.1
Cao, W.F.2
-
44
-
-
67349112100
-
Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis
-
19038363 10.1016/j.bbalip.2008.10.010 1:CAS:528:DC%2BD1MXntVKls7c%3D
-
Wendel AA, Lewin TM, Coleman RA (2009) Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis. Biochim Biophys Acta 1791:501-506
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 501-506
-
-
Wendel, A.A.1
Lewin, T.M.2
Coleman, R.A.3
-
45
-
-
21844451391
-
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
-
15878874 10.1074/jbc.M503181200 1:CAS:528:DC%2BD2MXlslylu7c%3D
-
Hammond LE, Neschen S, Romanelli AJ, Cline GW, Ilkayeva OR, Shulman GI, Muoio DM, Coleman RA (2005) Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. J Biol Chem 280:25629-25636
-
(2005)
J Biol Chem
, vol.280
, pp. 25629-25636
-
-
Hammond, L.E.1
Neschen, S.2
Romanelli, A.J.3
Cline, G.W.4
Ilkayeva, O.R.5
Shulman, G.I.6
Muoio, D.M.7
Coleman, R.A.8
-
46
-
-
33847006599
-
The liver X receptor (LXR) and hepatic lipogenes. I: The carbohydrate-response element-binding protein is a target gene of LXR
-
17107947 10.1074/jbc.M605023200 1:CAS:528:DC%2BD2sXkslCi
-
Cha JY, Repa JJ (2007) The liver X receptor (LXR) and hepatic lipogenes. i: the carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem 282:743-751
-
(2007)
J Biol Chem
, vol.282
, pp. 743-751
-
-
Cha, J.Y.1
Repa, J.J.2
-
47
-
-
84863700580
-
Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology
-
22705711 10.1016/j.plipres.2012.06.001 1:CAS:528:DC%2BC38XhtlamtrvN
-
Liu Q, Siloto RM, Lehner R, Stone SJ, Weselake RJ (2012) Acyl-CoA:diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology. Prog Lipid Res 51:350-377
-
(2012)
Prog Lipid Res
, vol.51
, pp. 350-377
-
-
Liu, Q.1
Siloto, R.M.2
Lehner, R.3
Stone, S.J.4
Weselake, R.J.5
-
48
-
-
33748757743
-
Colocalization of SCD1 and DGAT2: Implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis
-
16751624 10.1194/jlr.M600172-JLR200 1:CAS:528:DC%2BD28Xpt1Gjsrs%3D
-
Man WC, Miyazaki M, Chu K, Ntambi J (2006) Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. J Lipid Res 47:1928-1939
-
(2006)
J Lipid Res
, vol.47
, pp. 1928-1939
-
-
Man, W.C.1
Miyazaki, M.2
Chu, K.3
Ntambi, J.4
-
49
-
-
0034958783
-
A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis
-
11441127 1:CAS:528:DC%2BD3MXlt1Kru7Y%3D
-
Miyazaki M, Kim YC, Ntambi JM (2001) A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. J Lipid Res 42:1018-1024
-
(2001)
J Lipid Res
, vol.42
, pp. 1018-1024
-
-
Miyazaki, M.1
Kim, Y.C.2
Ntambi, J.M.3
-
50
-
-
36448991861
-
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
-
18054317 10.1016/j.cmet.2007.10.014 1:CAS:528:DC%2BD2sXhsVektb%2FL
-
Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, Ntambi JM (2007) Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab 6:484-496
-
(2007)
Cell Metab
, vol.6
, pp. 484-496
-
-
Miyazaki, M.1
Flowers, M.T.2
Sampath, H.3
Chu, K.4
Otzelberger, C.5
Liu, X.6
Ntambi, J.M.7
-
51
-
-
79551593270
-
Liver mitochondria and insulin resistance
-
21079817 1:CAS:528:DC%2BC3MXpt1Wltg%3D%3D
-
Vial G, Dubouchaud H, Leverve XM (2010) Liver mitochondria and insulin resistance. Acta Biochim Pol 57:389-392
-
(2010)
Acta Biochim Pol
, vol.57
, pp. 389-392
-
-
Vial, G.1
Dubouchaud, H.2
Leverve, X.M.3
-
52
-
-
45549089456
-
A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels
-
18349115 10.1152/ajpendo.00497.2007 1:CAS:528:DC%2BD1cXlvFCisrw%3D
-
Stefanovic-Racic M, Perdomo G, Mantell BS, Sipula IJ, Brown NF, O'Doherty RM (2008) A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels. Am J Physiol Endocrinol Metab 294:E969-E977
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Stefanovic-Racic, M.1
Perdomo, G.2
Mantell, B.S.3
Sipula, I.J.4
Brown, N.F.5
O'Doherty, R.M.6
-
53
-
-
79959550724
-
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
-
21465509 10.1002/hep.24338 1:CAS:528:DC%2BC3MXnvF2nuro%3D
-
Wu JW, Wang SP, Alvarez F, Casavant S, Gauthier N, Abed L, Soni KG, Yang G, Mitchell GA (2011) Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. Hepatology 54:122-132
-
(2011)
Hepatology
, vol.54
, pp. 122-132
-
-
Wu, J.W.1
Wang, S.P.2
Alvarez, F.3
Casavant, S.4
Gauthier, N.5
Abed, L.6
Soni, K.G.7
Yang, G.8
Mitchell, G.A.9
-
54
-
-
57349116780
-
Causes and metabolic consequences of fatty liver
-
18723451 10.1210/er.2008-0009 1:CAS:528:DC%2BD1MXmt1yjug%3D%3D
-
Stefan N, Kantartzis K, Häring HU (2008) Causes and metabolic consequences of fatty liver. Endocr Rev 29:939-960
-
(2008)
Endocr Rev
, vol.29
, pp. 939-960
-
-
Stefan, N.1
Kantartzis, K.2
Häring, H.U.3
-
55
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
21532591 10.1038/nature09968 1:CAS:528:DC%2BC3MXlsVGlsLc%3D
-
Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS (2011) Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 473:528-531
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
Hide, W.6
Lin, X.7
Watkins, S.M.8
Ivanov, A.R.9
Hotamisligil, G.S.10
-
56
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
15486293 10.1126/science.1103160
-
Özcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Özdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Özcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Özdelen, E.6
Tuncman, G.7
Görgün, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
57
-
-
34347406521
-
SREBP-1c transcription factor and lipid homeostasis: Clinical perspective
-
17344645 10.1159/000100426
-
Ferré P, Foufelle F (2007) SREBP-1c transcription factor and lipid homeostasis: clinical perspective. Horm Res 68:72-82
-
(2007)
Horm Res
, vol.68
, pp. 72-82
-
-
Ferré, P.1
Foufelle, F.2
-
58
-
-
69249213918
-
Pharmacological inhibition of stearoyl-CoA desaturase 1 improves insulin sensitivity in insulin-resistant rat models
-
19616540 10.1016/j.ejphar.2009.07.004 1:CAS:528:DC%2BD1MXhtVKkt7fM
-
Issandou M, Bouillot A, Brusq JM, Forest MC, Grillot D, Guillard R, Martin S, Michiels C, Sulpice T, Daugan A (2009) Pharmacological inhibition of stearoyl-CoA desaturase 1 improves insulin sensitivity in insulin-resistant rat models. Eur J Pharmacol 618:28-36
-
(2009)
Eur J Pharmacol
, vol.618
, pp. 28-36
-
-
Issandou, M.1
Bouillot, A.2
Brusq, J.M.3
Forest, M.C.4
Grillot, D.5
Guillard, R.6
Martin, S.7
Michiels, C.8
Sulpice, T.9
Daugan, A.10
-
59
-
-
34948904815
-
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
-
17906635 10.1038/nm1662 1:CAS:528:DC%2BD2sXhtFagsbzL
-
Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, Sekiya M, Ohashi K, Hasty AH, Nakagawa Y, Takahashi A, Suzuki H, Yatoh S, Sone H, Toyoshima H, Osuga J, Yamada N (2007) Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Nat Med 13:1193-1202
-
(2007)
Nat Med
, vol.13
, pp. 1193-1202
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Kato, T.4
Atsumi, A.5
Yamamoto, T.6
Inoue, N.7
Ishikawa, M.8
Okada, S.9
Ishigaki, N.10
Iwasaki, H.11
Iwasaki, Y.12
Karasawa, T.13
Kumadaki, S.14
Matsui, T.15
Sekiya, M.16
Ohashi, K.17
Hasty, A.H.18
Nakagawa, Y.19
Takahashi, A.20
Suzuki, H.21
Yatoh, S.22
Sone, H.23
Toyoshima, H.24
Osuga, J.25
Yamada, N.26
more..
-
60
-
-
66449137379
-
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
-
19363290 10.1172/JCI37007 1:CAS:528:DC%2BD1MXlsFyrsbg%3D
-
Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F (2009) GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. J Clin Invest 119:1201-1215
-
(2009)
J Clin Invest
, vol.119
, pp. 1201-1215
-
-
Kammoun, H.L.1
Chabanon, H.2
Hainault, I.3
Luquet, S.4
Magnan, C.5
Koike, T.6
Ferré, P.7
Foufelle, F.8
-
61
-
-
0037453056
-
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
-
12629214 10.1073/pnas.0630588100 1:CAS:528:DC%2BD3sXisVCnsLs%3D
-
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV Jr, Ory DS, Schaffer JE (2003) Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA 100:3077-3082
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3077-3082
-
-
Listenberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese, Jr.R.V.5
Ory, D.S.6
Schaffer, J.E.7
-
63
-
-
44649111219
-
SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease
-
18360697 1:CAS:528:DC%2BD1cXkslKqtrs%3D
-
Kohjima M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, Fujino T, Yada M, Yada R, Harada N, Enjoji M, Takayanagi R, Nakamuta M (2008) SREBP-1c, regulated by the insulin and AMPK signaling pathways, plays a role in nonalcoholic fatty liver disease. Int J Mol Med 21:507-511
-
(2008)
Int J Mol Med
, vol.21
, pp. 507-511
-
-
Kohjima, M.1
Higuchi, N.2
Kato, M.3
Kotoh, K.4
Yoshimoto, T.5
Fujino, T.6
Yada, M.7
Yada, R.8
Harada, N.9
Enjoji, M.10
Takayanagi, R.11
Nakamuta, M.12
-
64
-
-
0036079637
-
Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity
-
11739082 1:CAS:528:DC%2BD38XlsVKlsQ%3D%3D
-
Diraison F, Dusserre E, Vidal H, Sothier M, Beylot M (2002) Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity. Am J Physiol Endocrinol Metab 282:E46-E51
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Diraison, F.1
Dusserre, E.2
Vidal, H.3
Sothier, M.4
Beylot, M.5
-
65
-
-
26244436986
-
Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men
-
16132958 10.1007/s00125-005-1897-x
-
Warensjö E, Risérus U, Vessby B (2005) Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia 48:1999-2005
-
(2005)
Diabetologia
, vol.48
, pp. 1999-2005
-
-
Warensjö, E.1
Risérus, U.2
Vessby, B.3
-
66
-
-
78149284997
-
Role of hepatic desaturases in obesity-related metabolic disorders
-
20823776 10.1097/MCO.0b013e32833ec41b 1:CAS:528:DC%2BC3cXhtlGmtbzL
-
Bjermo H, Risérus U (2010) Role of hepatic desaturases in obesity-related metabolic disorders. Curr Opin Clin Nutr Metab Care 13:703-708
-
(2010)
Curr Opin Clin Nutr Metab Care
, vol.13
, pp. 703-708
-
-
Bjermo, H.1
Risérus, U.2
-
67
-
-
77954143472
-
Decreased liver fatty acid delta-6 and delta-5 desaturase activity in obese patients
-
19875987 10.1038/oby.2009.379 1:CAS:528:DC%2BC3cXnvFymtLo%3D
-
Araya J, Rodrigo R, Pettinelli P, Araya AV, Poniachik J, Videla LA (2010) Decreased liver fatty acid delta-6 and delta-5 desaturase activity in obese patients. Obesity 18:1460-1463
-
(2010)
Obesity
, vol.18
, pp. 1460-1463
-
-
Araya, J.1
Rodrigo, R.2
Pettinelli, P.3
Araya, A.V.4
Poniachik, J.5
Videla, L.A.6
-
68
-
-
33846868166
-
Polyunsaturated fatty acid pattern in liver and erythrocyte phospholipids from obese patients
-
17228028 10.1038/oby.2007.518 1:CAS:528:DC%2BD2sXosVeisr8%3D
-
Elizondo A, Araya J, Rodrigo R, Poniachik J, Csendes A, Maluenda F, Díaz JC, Signorini C, Sgherri C, Comporti M, Videla LA (2007) Polyunsaturated fatty acid pattern in liver and erythrocyte phospholipids from obese patients. Obesity 15:24-31
-
(2007)
Obesity
, vol.15
, pp. 24-31
-
-
Elizondo, A.1
Araya, J.2
Rodrigo, R.3
Poniachik, J.4
Csendes, A.5
Maluenda, F.6
Díaz, J.C.7
Signorini, C.8
Sgherri, C.9
Comporti, M.10
Videla, L.A.11
|