-
1
-
-
64649096897
-
Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity
-
M. Ahmadian, R.E. Duncan, K.A. Varady, D. Frasson, M.K. Hellerstein, A.L. Birkenfeld, V.T. Samuel, G.I. Shulman, Y. Wang, C. Kang, and H.S. Sul Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity Diabetes 58 2009 855 866
-
(2009)
Diabetes
, vol.58
, pp. 855-866
-
-
Ahmadian, M.1
Duncan, R.E.2
Varady, K.A.3
Frasson, D.4
Hellerstein, M.K.5
Birkenfeld, A.L.6
Samuel, V.T.7
Shulman, G.I.8
Wang, Y.9
Kang, C.10
Sul, H.S.11
-
2
-
-
79958047295
-
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
-
M. Ahmadian, M.J. Abbott, T. Tang, C.S. Hudak, Y. Kim, M. Bruss, M.K. Hellerstein, H.Y. Lee, V.T. Samuel, and G.I. Shulman Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype Cell Metab. 13 2011 739 748
-
(2011)
Cell Metab.
, vol.13
, pp. 739-748
-
-
Ahmadian, M.1
Abbott, M.J.2
Tang, T.3
Hudak, C.S.4
Kim, Y.5
Bruss, M.6
Hellerstein, M.K.7
Lee, H.Y.8
Samuel, V.T.9
Shulman, G.I.10
-
3
-
-
80055076208
-
Positional cloning of a type 2 diabetes quantitative trait locus; Tomosyn-2, a negative regulator of insulin secretion
-
S. Bhatnagar, A.T. Oler, M.E. Rabaglia, D.S. Stapleton, K.L. Schueler, N.A. Truchan, S.L. Worzella, J.P. Stoehr, S.M. Clee, and B.S. Yandell Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion PLoS Genet. 7 2011 e1002323
-
(2011)
PLoS Genet.
, vol.7
, pp. 1002323
-
-
Bhatnagar, S.1
Oler, A.T.2
Rabaglia, M.E.3
Stapleton, D.S.4
Schueler, K.L.5
Truchan, N.A.6
Worzella, S.L.7
Stoehr, J.P.8
Clee, S.M.9
Yandell, B.S.10
-
4
-
-
9144262378
-
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
-
L. Cheng, G. Ding, Q. Qin, Y. Huang, W. Lewis, N. He, R.M. Evans, M.D. Schneider, F.A. Brako, and Y. Xiao Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy Nat. Med. 10 2004 1245 1250
-
(2004)
Nat. Med.
, vol.10
, pp. 1245-1250
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Huang, Y.4
Lewis, W.5
He, N.6
Evans, R.M.7
Schneider, M.D.8
Brako, F.A.9
Xiao, Y.10
-
5
-
-
84860567700
-
Fuel-stimulated insulin secretion depends upon mitochondria activation and the integration of mitochondrial and cytosolic substrate cycles
-
G.W. Cline Fuel-stimulated insulin secretion depends upon mitochondria activation and the integration of mitochondrial and cytosolic substrate cycles Diabetes Metab. J. 35 2011 458 465
-
(2011)
Diabetes Metab. J.
, vol.35
, pp. 458-465
-
-
Cline, G.W.1
-
6
-
-
0032545293
-
The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets
-
P. Detimary, S. Dejonghe, Z. Ling, D. Pipeleers, F. Schuit, and J.C. Henquin The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets J. Biol. Chem. 273 1998 33905 33908
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33905-33908
-
-
Detimary, P.1
Dejonghe, S.2
Ling, Z.3
Pipeleers, D.4
Schuit, F.5
Henquin, J.C.6
-
7
-
-
35748954800
-
Regulation of lipolysis in adipocytes
-
R.E. Duncan, M. Ahmadian, K. Jaworski, E. Sarkadi-Nagy, and H.S. Sul Regulation of lipolysis in adipocytes Annu. Rev. Nutr. 27 2007 79 101
-
(2007)
Annu. Rev. Nutr.
, vol.27
, pp. 79-101
-
-
Duncan, R.E.1
Ahmadian, M.2
Jaworski, K.3
Sarkadi-Nagy, E.4
Sul, H.S.5
-
8
-
-
77949492902
-
Characterization of desnutrin functional domains: Critical residues for triacylglycerol hydrolysis in cultured cells
-
R.E. Duncan, Y. Wang, M. Ahmadian, J. Lu, E. Sarkadi-Nagy, and H.S. Sul Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells J. Lipid Res. 51 2010 309 317
-
(2010)
J. Lipid Res.
, vol.51
, pp. 309-317
-
-
Duncan, R.E.1
Wang, Y.2
Ahmadian, M.3
Lu, J.4
Sarkadi-Nagy, E.5
Sul, H.S.6
-
9
-
-
77955492173
-
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
-
J.A. Ehses, D.T. Meier, S. Wueest, J. Rytka, S. Boller, P.Y. Wielinga, A. Schraenen, K. Lemaire, S. Debray, and L. Van Lommel Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet Diabetologia 53 2010 1795 1806
-
(2010)
Diabetologia
, vol.53
, pp. 1795-1806
-
-
Ehses, J.A.1
Meier, D.T.2
Wueest, S.3
Rytka, J.4
Boller, S.5
Wielinga, P.Y.6
Schraenen, A.7
Lemaire, K.8
Debray, S.9
Van Lommel, L.10
-
10
-
-
64649092274
-
Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure
-
C. Evans-Molina, R.D. Robbins, T. Kono, S.A. Tersey, G.L. Vestermark, C.S. Nunemaker, J.C. Garmey, T.G. Deering, S.R. Keller, B. Maier, and R.G. Mirmira Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure Mol. Cell. Biol. 29 2009 2053 2067
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2053-2067
-
-
Evans-Molina, C.1
Robbins, R.D.2
Kono, T.3
Tersey, S.A.4
Vestermark, G.L.5
Nunemaker, C.S.6
Garmey, J.C.7
Deering, T.G.8
Keller, S.R.9
Maier, B.10
Mirmira, R.G.11
-
11
-
-
34748883744
-
Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance
-
M. Fex, N. Wierup, M.D. Nitert, M. Ristow, and H. Mulder Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance J. Endocrinol. 194 2007 551 555
-
(2007)
J. Endocrinol.
, vol.194
, pp. 551-555
-
-
Fex, M.1
Wierup, N.2
Nitert, M.D.3
Ristow, M.4
Mulder, H.5
-
12
-
-
58149473940
-
A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis
-
M. Fex, G. Haemmerle, N. Wierup, M. Dekker-Nitert, M. Rehn, M. Ristow, R. Zechner, F. Sundler, C. Holm, L. Eliasson, and H. Mulder A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis Diabetologia 52 2009 271 280
-
(2009)
Diabetologia
, vol.52
, pp. 271-280
-
-
Fex, M.1
Haemmerle, G.2
Wierup, N.3
Dekker-Nitert, M.4
Rehn, M.5
Ristow, M.6
Zechner, R.7
Sundler, F.8
Holm, C.9
Eliasson, L.10
Mulder, H.11
-
13
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
G. Haemmerle, A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, J. Rozman, G. Heldmaier, R. Maier, C. Theussl, and S. Eder Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase Science 312 2006 734 737
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
Gorkiewicz, G.4
Meyer, C.5
Rozman, J.6
Heldmaier, G.7
Maier, R.8
Theussl, C.9
Eder, S.10
-
14
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
-
G. Haemmerle, T. Moustafa, G. Woelkart, S. Büttner, A. Schmidt, T. van de Weijer, M. Hesselink, D. Jaeger, P.C. Kienesberger, and K. Zierler ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 Nat. Med. 17 2011 1076 1085
-
(2011)
Nat. Med.
, vol.17
, pp. 1076-1085
-
-
Haemmerle, G.1
Moustafa, T.2
Woelkart, G.3
Büttner, S.4
Schmidt, A.5
Van De Weijer, T.6
Hesselink, M.7
Jaeger, D.8
Kienesberger, P.C.9
Zierler, K.10
-
15
-
-
61349111509
-
Insulin granule biogenesis, trafficking and exocytosis
-
J.C. Hou, L. Min, and J.E. Pessin Insulin granule biogenesis, trafficking and exocytosis Vitam. Horm. 80 2009 473 506
-
(2009)
Vitam. Horm.
, vol.80
, pp. 473-506
-
-
Hou, J.C.1
Min, L.2
Pessin, J.E.3
-
16
-
-
78650851786
-
Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation
-
A.J. Hoy, C.R. Bruce, S.M. Turpin, A.J. Morris, M.A. Febbraio, and M.J. Watt Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation Endocrinology 152 2011 48 58
-
(2011)
Endocrinology
, vol.152
, pp. 48-58
-
-
Hoy, A.J.1
Bruce, C.R.2
Turpin, S.M.3
Morris, A.J.4
Febbraio, M.A.5
Watt, M.J.6
-
17
-
-
10344262633
-
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
-
C.M. Jenkins, D.J. Mancuso, W. Yan, H.F. Sims, B. Gibson, and R.W. Gross Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities J. Biol. Chem. 279 2004 48968 48975
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48968-48975
-
-
Jenkins, C.M.1
Mancuso, D.J.2
Yan, W.3
Sims, H.F.4
Gibson, B.5
Gross, R.W.6
-
19
-
-
0032586671
-
Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: Free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose
-
M. Komatsu, H. Yajima, S. Yamada, T. Kaneko, Y. Sato, K. Yamauchi, K. Hashizume, and T. Aizawa Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose Diabetes 48 1999 1543 1549
-
(1999)
Diabetes
, vol.48
, pp. 1543-1549
-
-
Komatsu, M.1
Yajima, H.2
Yamada, S.3
Kaneko, T.4
Sato, Y.5
Yamauchi, K.6
Hashizume, K.7
Aizawa, T.8
-
20
-
-
9644260562
-
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus
-
N. Kubota, Y. Terauchi, K. Tobe, W. Yano, R. Suzuki, K. Ueki, I. Takamoto, H. Satoh, T. Maki, and T. Kubota Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus J. Clin. Invest. 114 2004 917 927
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 917-927
-
-
Kubota, N.1
Terauchi, Y.2
Tobe, K.3
Yano, W.4
Suzuki, R.5
Ueki, K.6
Takamoto, I.7
Satoh, H.8
Maki, T.9
Kubota, T.10
-
21
-
-
33646384957
-
RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function
-
J.Y. Lee, M. Ristow, X. Lin, M.F. White, M.A. Magnuson, and L. Hennighausen RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function J. Biol. Chem. 281 2006 2649 2653
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2649-2653
-
-
Lee, J.Y.1
Ristow, M.2
Lin, X.3
White, M.F.4
Magnuson, M.A.5
Hennighausen, L.6
-
22
-
-
0942265525
-
A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells
-
H. Lindvall, P. Nevsten, K. Ström, R. Wallenberg, F. Sundler, D. Langin, M.S. Winzell, and C. Holm A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells J. Biol. Chem. 279 2004 3828 3836
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3828-3836
-
-
Lindvall, H.1
Nevsten, P.2
Ström, K.3
Wallenberg, R.4
Sundler, F.5
Langin, D.6
Winzell, M.S.7
Holm, C.8
-
23
-
-
78149424683
-
Tamoxifen-independent recombination in the RIP-CreER mouse
-
Y. Liu, J. Suckale, J. Masjkur, M.G. Magro, A. Steffen, K. Anastassiadis, and M. Solimena Tamoxifen-independent recombination in the RIP-CreER mouse PLoS ONE 5 2010 e13533
-
(2010)
PLoS ONE
, vol.5
, pp. 13533
-
-
Liu, Y.1
Suckale, J.2
Masjkur, J.3
Magro, M.G.4
Steffen, A.5
Anastassiadis, K.6
Solimena, M.7
-
24
-
-
77449154126
-
Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes
-
H. Lu, V. Koshkin, E.M. Allister, A.V. Gyulkhandanyan, and M.B. Wheeler Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes Diabetes 59 2010 448 459
-
(2010)
Diabetes
, vol.59
, pp. 448-459
-
-
Lu, H.1
Koshkin, V.2
Allister, E.M.3
Gyulkhandanyan, A.V.4
Wheeler, M.B.5
-
25
-
-
7044260753
-
Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet
-
J. Matsui, Y. Terauchi, N. Kubota, I. Takamoto, K. Eto, T. Yamashita, K. Komeda, T. Yamauchi, J. Kamon, and S. Kita Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet Diabetes 53 2004 2844 2854
-
(2004)
Diabetes
, vol.53
, pp. 2844-2854
-
-
Matsui, J.1
Terauchi, Y.2
Kubota, N.3
Takamoto, I.4
Eto, K.5
Yamashita, T.6
Komeda, K.7
Yamauchi, T.8
Kamon, J.9
Kita, S.10
-
26
-
-
48449094498
-
AMPK and PPARdelta agonists are exercise mimetics
-
V.A. Narkar, M. Downes, R.T. Yu, E. Embler, Y.X. Wang, E. Banayo, M.M. Mihaylova, M.C. Nelson, Y. Zou, and H. Juguilon AMPK and PPARdelta agonists are exercise mimetics Cell 134 2008 405 415
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
Banayo, E.6
Mihaylova, M.M.7
Nelson, M.C.8
Zou, Y.9
Juguilon, H.10
-
27
-
-
52249114681
-
The islet beta-cell: Fuel responsive and vulnerable
-
C.J. Nolan, and M. Prentki The islet beta-cell: fuel responsive and vulnerable Trends Endocrinol. Metab. 19 2008 285 291
-
(2008)
Trends Endocrinol. Metab.
, vol.19
, pp. 285-291
-
-
Nolan, C.J.1
Prentki, M.2
-
28
-
-
77649198252
-
Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase
-
Y. Okazaki, K. Eto, T. Yamashita, M. Okamoto, M. Ohsugi, M. Noda, Y. Terauchi, K. Ueki, and T. Kadowaki Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase Endocr. J. 57 2010 141 152
-
(2010)
Endocr. J.
, vol.57
, pp. 141-152
-
-
Okazaki, Y.1
Eto, K.2
Yamashita, T.3
Okamoto, M.4
Ohsugi, M.5
Noda, M.6
Terauchi, Y.7
Ueki, K.8
Kadowaki, T.9
-
29
-
-
3042781392
-
Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1
-
M.L. Peyot, C.J. Nolan, K. Soni, E. Joly, R. Lussier, B.E. Corkey, S.P. Wang, G.A. Mitchell, and M. Prentki Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1 Diabetes 53 2004 1733 1742
-
(2004)
Diabetes
, vol.53
, pp. 1733-1742
-
-
Peyot, M.L.1
Nolan, C.J.2
Soni, K.3
Joly, E.4
Lussier, R.5
Corkey, B.E.6
Wang, S.P.7
Mitchell, G.A.8
Prentki, M.9
-
30
-
-
67650529854
-
Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion
-
M.L. Peyot, C. Guay, M.G. Latour, J. Lamontagne, R. Lussier, M. Pineda, N.B. Ruderman, G. Haemmerle, R. Zechner, and E. Joly Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion J. Biol. Chem. 284 2009 16848 16859
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16848-16859
-
-
Peyot, M.L.1
Guay, C.2
Latour, M.G.3
Lamontagne, J.4
Lussier, R.5
Pineda, M.6
Ruderman, N.B.7
Haemmerle, G.8
Zechner, R.9
Joly, E.10
-
31
-
-
77952683867
-
PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction
-
K. Ravnskjaer, F. Frigerio, M. Boergesen, T. Nielsen, P. Maechler, and S. Mandrup PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction J. Lipid Res. 51 2010 1370 1379
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1370-1379
-
-
Ravnskjaer, K.1
Frigerio, F.2
Boergesen, M.3
Nielsen, T.4
Maechler, P.5
Mandrup, S.6
-
32
-
-
80051600918
-
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
-
L.D. Roberts, A.J. Murray, D. Menassa, T. Ashmore, A.W. Nicholls, and J.L. Griffin The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue Genome Biol. 12 2011 R75
-
(2011)
Genome Biol.
, vol.12
, pp. 75
-
-
Roberts, L.D.1
Murray, A.J.2
Menassa, D.3
Ashmore, T.4
Nicholls, A.W.5
Griffin, J.L.6
-
33
-
-
0035461405
-
A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: A study in hormone-sensitive lipase-deficient mice
-
R. Roduit, P. Masiello, S.P. Wang, H. Li, G.A. Mitchell, and M. Prentki A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice Diabetes 50 2001 1970 1975
-
(2001)
Diabetes
, vol.50
, pp. 1970-1975
-
-
Roduit, R.1
Masiello, P.2
Wang, S.P.3
Li, H.4
Mitchell, G.A.5
Prentki, M.6
-
34
-
-
68149156892
-
Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells
-
H.A. Russ, P. Ravassard, J. Kerr-Conte, F. Pattou, and S. Efrat Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells PLoS ONE 4 2009 e6417
-
(2009)
PLoS ONE
, vol.4
, pp. 6417
-
-
Russ, H.A.1
Ravassard, P.2
Kerr-Conte, J.3
Pattou, F.4
Efrat, S.5
-
35
-
-
0036182137
-
Lipotoxic diseases
-
R.H. Unger Lipotoxic diseases Annu. Rev. Med. 53 2002 319 336
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
36
-
-
8744297386
-
Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
-
J.A. Villena, S. Roy, E. Sarkadi-Nagy, K.H. Kim, and H.S. Sul Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis J. Biol. Chem. 279 2004 47066 47075
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47066-47075
-
-
Villena, J.A.1
Roy, S.2
Sarkadi-Nagy, E.3
Kim, K.H.4
Sul, H.S.5
-
37
-
-
73949116134
-
Activation of PPARdelta up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic beta-cells
-
J. Wan, L. Jiang, Q. Lü, L. Ke, X. Li, and N. Tong Activation of PPARdelta up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic beta-cells Biochem. Biophys. Res. Commun. 391 2010 1567 1572
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 1567-1572
-
-
Wan, J.1
Jiang, L.2
Lü, Q.3
Ke, L.4
Li, X.5
Tong, N.6
-
38
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by PPARdelta
-
Y.X. Wang, C.L. Zhang, R.T. Yu, H.K. Cho, M.C. Nelson, C.R. Bayuga-Ocampo, J. Ham, H. Kang, and R.M. Evans Regulation of muscle fiber type and running endurance by PPARdelta PLoS Biol. 2 2004 e294
-
(2004)
PLoS Biol.
, vol.2
, pp. 294
-
-
Wang, Y.X.1
Zhang, C.L.2
Yu, R.T.3
Cho, H.K.4
Nelson, M.C.5
Bayuga-Ocampo, C.R.6
Ham, J.7
Kang, H.8
Evans, R.M.9
-
39
-
-
84866767154
-
The mitochondrial Atp8 mutation induces mitochondrial ROS generation, secretory dysfunction, and β-cell mass adaptation in conplastic B6-mtFVB mice
-
H. Weiss, L. Wester-Rosenloef, C. Koch, F. Koch, S. Baltrusch, M. Tiedge, and S. Ibrahim The mitochondrial Atp8 mutation induces mitochondrial ROS generation, secretory dysfunction, and β-cell mass adaptation in conplastic B6-mtFVB mice Endocrinology 153 2012 4666 4676
-
(2012)
Endocrinology
, vol.153
, pp. 4666-4676
-
-
Weiss, H.1
Wester-Rosenloef, L.2
Koch, C.3
Koch, F.4
Baltrusch, S.5
Tiedge, M.6
Ibrahim, S.7
-
40
-
-
84860992488
-
A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets
-
J.D. Wikstrom, S.B. Sereda, L. Stiles, A. Elorza, E.M. Allister, A. Neilson, D.A. Ferrick, M.B. Wheeler, and O.S. Shirihai A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets PLoS ONE 7 2012 e33023
-
(2012)
PLoS ONE
, vol.7
, pp. 33023
-
-
Wikstrom, J.D.1
Sereda, S.B.2
Stiles, L.3
Elorza, A.4
Allister, E.M.5
Neilson, A.6
Ferrick, D.A.7
Wheeler, M.B.8
Shirihai, O.S.9
-
41
-
-
0035489034
-
The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose
-
M.S. Winzell, H. Svensson, P. Arner, B. Ahrén, and C. Holm The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose Diabetes 50 2001 2225 2230
-
(2001)
Diabetes
, vol.50
, pp. 2225-2230
-
-
Winzell, M.S.1
Svensson, H.2
Arner, P.3
Ahrén, B.4
Holm, C.5
-
42
-
-
0037414442
-
Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding
-
M.S. Winzell, C. Holm, and B. Ahrén Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding Biochem. Biophys. Res. Commun. 304 2003 273 278
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 273-278
-
-
Winzell, M.S.1
Holm, C.2
Ahrén, B.3
-
43
-
-
70649114413
-
Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice
-
M.S. Winzell, E.M. Wulff, G.S. Olsen, P. Sauerberg, C.F. Gotfredsen, and B. Ahrén Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice Eur. J. Pharmacol. 626 2010 297 305
-
(2010)
Eur. J. Pharmacol.
, vol.626
, pp. 297-305
-
-
Winzell, M.S.1
Wulff, E.M.2
Olsen, G.S.3
Sauerberg, P.4
Gotfredsen, C.F.5
Ahrén, B.6
-
44
-
-
84856008795
-
Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels
-
A. Yessoufou, and W. Wahli Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels Swiss Med. Wkly. 140 2010 w13071
-
(2010)
Swiss Med. Wkly.
, vol.140
, pp. 13071
-
-
Yessoufou, A.1
Wahli, W.2
-
45
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
R. Zimmermann, J.G. Strauss, G. Haemmerle, G. Schoiswohl, R. Birner-Gruenberger, M. Riederer, A. Lass, G. Neuberger, F. Eisenhaber, A. Hermetter, and R. Zechner Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase Science 306 2004 1383 1386
-
(2004)
Science
, vol.306
, pp. 1383-1386
-
-
Zimmermann, R.1
Strauss, J.G.2
Haemmerle, G.3
Schoiswohl, G.4
Birner-Gruenberger, R.5
Riederer, M.6
Lass, A.7
Neuberger, G.8
Eisenhaber, F.9
Hermetter, A.10
Zechner, R.11
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