Decreased insulin secretion and accumulation of triglyceride in β cells overexpressing a dominant-negative form of AMP-activated protein kinase

Endocrine Journal

Volumn 57, Issue 2, 2010, Pages 141-152

  Okazaki, Yukiko ^a   Kazuhiro, Eto ^b   Yamashita, Tokuyuki ^c   Okamoto, Masayuki ^c   Ohsugi, Mitsuru ^a   Noda, Mitsuhiko ^d   Terauchi, Yasuo ^e   Ueki, Kohjiro ^a   Kadowaki, Takashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^d NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^e YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

oxidation; AMPK; Insulin secretion; Triglyceride

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOVIRUS VECTOR; ANTIBODY; BETA GALACTOSIDASE; EPITOPE; GLIBENCLAMIDE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MESSENGER RNA; MYC PROTEIN; PALMITIC ACID; POTASSIUM CHLORIDE; THREONINE; TRIACYLGLYCEROL;

ADENOVIRUS INFECTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; INSULIN RELEASE; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VIRUS TITRATION; WESTERN BLOTTING;

ACETYL-COA CARBOXYLASE; AMP-ACTIVATED PROTEIN KINASES; GLYBURIDE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; PALMITATES; POTASSIUM CHLORIDE; TRIGLYCERIDES; TUMOR CELLS, CULTURED;

EID: 77649198252     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K09E-284     Document Type: Article

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