The mitochondrial Atp8 mutation induces mitochondrial ROS generation, secretory dysfunction, and β-cell mass adaptation in conplastic B6-mt FVB mice

Endocrinology

Volumn 153, Issue 10, 2012, Pages 4666-4676

  Weiss, Heike ^a   Wester Rosenloef, Lena ^a   Koch, Christiane ^a   Koch, Franziska ^a   Baltrusch, Simone ^a   Tiedge, Markus ^a   Ibrahim, Saleh ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; MITOCHONDRIAL DNA; PALMITIC ACID; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE PROTEIN 8; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE MUTATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; POINT MUTATION; PRIORITY JOURNAL; WEIGHT GAIN;

ADENOSINE TRIPHOSPHATE; ANIMALS; BODY WEIGHT; DNA, MITOCHONDRIAL; GLUCOSE; GLUCOSE INTOLERANCE; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MUTATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84866767154     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1296     Document Type: Article

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