메뉴 건너뛰기




Volumn 51, Issue 2, 2010, Pages 309-317

Characterization of desnutrin functional domains: Critical residues for triacylglycerol hydrolysis in cultured cells

Author keywords

Adipose triglyceride lipase; C terminal region; Hydrolase; Lipid substrate binding domain; Mutant; N terminal region; Neutral lipid storage disease with myopathy; Patatin like phospholipase A domain containing

Indexed keywords

DESNUTRIN; FAT DROPLET; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; CARBOXYLESTERASE; DESNUTRIN PROTEIN, MOUSE;

EID: 77949492902     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M000729     Document Type: Article
Times cited : (41)

References (26)
  • 4
    • 10344262633 scopus 로고    scopus 로고
    • Identifi cation, cloning, expression, and purifi cation of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
    • Jenkins, C. M., D. J. Mancuso, W. Yan, H. F. Sims, B. Gibson, and R. W. Gross. 2004. Identifi cation, cloning, expression, and purifi cation of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J. Biol. Chem. 279: 48968-48975.
    • (2004) J. Biol. Chem. , vol.279 , pp. 48968-48975
    • Jenkins, C.M.1    Mancuso, D.J.2    Yan, W.3    Sims, H.F.4    Gibson, B.5    Gross., R.W.6
  • 5
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: Ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena, J. A., S. Roy, E. Sarkadi-Nagy, K. H. Kim, and H. S. Sul. 2004. Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J. Biol. Chem. 279: 47066-47075.
    • (2004) J. Biol. Chem. , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul., H.S.5
  • 11
    • 37049010298 scopus 로고    scopus 로고
    • Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy
    • Akiyama, M., K. Sakai, M. Ogawa, J. R. McMillan, D. Sawamura, and H. Shimizu. 2007. Novel duplication mutation in the patatin domain of adipose triglyceride lipase (PNPLA2) in neutral lipid storage disease with severe myopathy. Muscle Nerve. 36: 856-859.
    • (2007) Muscle Nerve. , vol.36 , pp. 856-859
    • Akiyama, M.1    Sakai, K.2    Ogawa, M.3    McMillan, J.R.4    Sawamura, D.5    Shimizu., H.6
  • 13
    • 47549087164 scopus 로고    scopus 로고
    • The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets
    • Kobayashi, K., T. Inoguchi, Y. Maeda, N. Nakashima, A. Kuwano, E. Eto, N. Ueno, S. Sasaki, F. Sawada, M. Fujii, et al. 2008. The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets. J. Clin. Endocrinol. Metab. 93: 2877-2884.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 2877-2884
    • Kobayashi, K.1    Inoguchi, T.2    Maeda, Y.3    Nakashima, N.4    Kuwano, A.5    Eto, E.6    Ueno, N.7    Sasaki, S.8    Sawada, F.9    Fujii, M.10
  • 15
    • 33845461566 scopus 로고    scopus 로고
    • A clean, more effi cient method for in-solution digestion of protein mixtures without detergent or urea
    • Kim, S. C., Y. Chen, S. Mirza, Y. Xu, J. Lee, P. Liu, and Y. Zhao. 2006. A clean, more effi cient method for in-solution digestion of protein mixtures without detergent or urea. J. Proteome Res. 5: 3446-3452.
    • (2006) J. Proteome Res. , vol.5 , pp. 3446-3452
    • Kim, S.C.1    Chen, Y.2    Mirza, S.3    Xu, Y.4    Lee, J.5    Liu, P.6    Zhao., Y.7
  • 16
    • 0026575834 scopus 로고
    • Synthesis and secretion of wild-type and mutant human plasma cholesteryl ester transfer protein in baculovirus-transfected insect cells: The carboxyl-terminal region is required for both lipoprotein binding and catalysis of transfer
    • Au-Young, J., and C. J. Fielding. 1992. Synthesis and secretion of wild-type and mutant human plasma cholesteryl ester transfer protein in baculovirus-transfected insect cells: The carboxyl-terminal region is required for both lipoprotein binding and catalysis of transfer. Proc. Natl. Acad. Sci. USA. 89: 4094-4098.
    • (1992) Proc. Natl. Acad. Sci. USA. , vol.89 , pp. 4094-4098
    • Au-Young, J.1    Fielding., C.J.2
  • 17
    • 0022539982 scopus 로고
    • 2+ and lipid-binding proteins
    • 2+ and lipid-binding proteins. FEBS Lett. 203: 99-103.
    • (1986) FEBS Lett. , vol.203 , pp. 99-103
    • Geisow, M.J.1
  • 18
    • 0034967147 scopus 로고    scopus 로고
    • Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells
    • Orlicky, D. J., J. DeGregori, and J. Schaack. 2001. Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells. J. Lipid Res. 42: 910-915.
    • (2001) J. Lipid Res. , vol.42 , pp. 910-915
    • Orlicky, D.J.1    Degregori, J.2    Schaack., J.3
  • 19
    • 54449092296 scopus 로고    scopus 로고
    • Identifi cation and functional characterization of Adipose-specifi c Phospholipase A2 (AdPLA)
    • Duncan, R. E., E. Sarkadi-Nagy, K. Jaworski, M. Ahmadian, and H. S. Sul. 2008. Identifi cation and functional characterization of Adipose-specifi c Phospholipase A2 (AdPLA). J. Biol. Chem. 283: 25428-25436.
    • (2008) J. Biol. Chem. , vol.283 , pp. 25428-25436
    • Duncan, R.E.1    Sarkadi-Nagy, E.2    Jaworski, K.3    Ahmadian, M.4    Sul., H.S.5
  • 20
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purifi cation
    • Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purifi cation. Can. J. Biochem. Physiol. 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer., W.J.2
  • 21
    • 59149100574 scopus 로고    scopus 로고
    • Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
    • Krintel, C., P. Osmark, M. R. Larsen, S. Resjo, D. T. Logan, and C. Holm. 2008. Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates. PLoS One. 3: e3756.
    • (2008) PLoS One. , vol.3
    • Krintel, C.1    Osmark, P.2    Larsen, M.R.3    Resjo, S.4    Logan, D.T.5    Holm., C.6
  • 23
    • 34548150017 scopus 로고    scopus 로고
    • Dynamic activity of lipid droplets: Protein phosphor-ylation and GTP-mediated protein translocation
    • Bartz, R., J. K. Zehmer, M. Zhu, Y. Chen, G. Serrero, Y. Zhao, and P. Liu. 2007. Dynamic activity of lipid droplets: protein phosphor-ylation and GTP-mediated protein translocation. J. Proteome Res. 6: 3256-3265.
    • (2007) J. Proteome Res. , vol.6 , pp. 3256-3265
    • Bartz, R.1    Zehmer, J.K.2    Zhu, M.3    Chen, Y.4    Serrero, G.5    Zhao, Y.6    Liu., P.7
  • 24
    • 0029845902 scopus 로고    scopus 로고
    • The nicotinamide dinucleotide binding motif: A comparison of nucleotide binding proteins
    • Bellamacina, C. R. 1996. The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins. FASEB J. 10: 1257-1269.
    • (1996) FASEB J. , vol.10 , pp. 1257-1269
    • Bellamacina, C.R.1
  • 25
    • 0033617291 scopus 로고    scopus 로고
    • Crystal structure of human cytosolic phospho-lipase A2 reveals a novel topology and catalytic mechanism
    • Dessen, A., J. Tang, H. Schmidt, M. Stahl, J. D. Clark, J. Seehra, and W. S. Somers. 1999. Crystal structure of human cytosolic phospho-lipase A2 reveals a novel topology and catalytic mechanism. Cell. 97: 349-360.
    • (1999) Cell. , vol.97 , pp. 349-360
    • Dessen, A.1    Tang, J.2    Schmidt, H.3    Stahl, M.4    Clark, J.D.5    Seehra, J.6    Somers., W.S.7
  • 26
    • 33244496395 scopus 로고    scopus 로고
    • Mutation of F417 but not L418 or L420 in the lipid binding domain decreases the activity of triacylglycerol hydrolase
    • Alam, M., D. Gilham, D. E. Vance, and R. Lehner. 2006. Mutation of F417 but not L418 or L420 in the lipid binding domain decreases the activity of triacylglycerol hydrolase. J. Lipid Res. 47: 375-383.
    • (2006) J. Lipid Res. , vol.47 , pp. 375-383
    • Alam, M.1    Gilham, D.2    Vance, D.E.3    Lehner., R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.