Modulating GPR40: Therapeutic promise and potential in diabetes

Drug Discovery Today

Volumn 18, Issue 23-24, 2013, Pages 1301-1308

  Poitout, Vincent ^a   Lin, Daniel C H ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMG 837; FASIGLIFAM; G PROTEIN COUPLED RECEPTOR 40; G PROTEIN COUPLED RECEPTOR 40 AGONIST; INSULIN; JTT 851; LY 2881835; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; FATTY ACID; FFAR1 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; GLUCOSE BLOOD LEVEL;

ALLOSTERISM; DRUG EFFECT; DRUG INDICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PHASE 2 CLINICAL TRIAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; AGONISTS; ANIMAL; DIABETES MELLITUS, TYPE 2; DRUG DESIGN; GLUCOSE BLOOD LEVEL; METABOLISM; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DRUG DESIGN; FATTY ACIDS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84889083042     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2013.09.003     Document Type: Review

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