G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2682-2692

  Ferdaoussi, M ^a,b   Bergeron, V ^a,b   Zarrouki, B ^a,b   Kolic, J ^c   Cantley, J ^d   Fielitz, J ^e,f   Olson, E N ^g   Prentki, M ^a,b   Biden, T ^d   MacDonald, P E ^c   Poitout, V ^a,b  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

^d ST VINCENT S HOSPITAL   (Australia)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Diacylglycerol; Filamentous actin; G protein coupled receptor; GPR40; Insulin secretion; Islet; Protein kinase D; Type 2 diabetes

Indexed keywords

DIACYLGLYCEROL; F ACTIN; G PROTEIN COUPLED RECEPTOR 40; GLUCOSE; INSULIN; LONG CHAIN FATTY ACID; OLEIC ACID; PROTEIN KINASE; PROTEIN KINASE C DELTA; SERINE;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; DEPOLYMERIZATION; INCUBATION TIME; INSULIN RELEASE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WILD TYPE;

ACTINS; ANIMALS; CELLS, CULTURED; DIGLYCERIDES; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; OLEIC ACID; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84866129127     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2650-x     Document Type: Article

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