Fatty acid receptor GPR40 mediates neuromicrovascular degeneration induced by transarachidonic acids in rodents

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 5, 2013, Pages 954-961

  Honoré, Jean Claude ^a,c   Kooli, Amna ^a,b   Hamel, David ^a,c   Alquier, Thierry ^c,d   Rivera, José Carlos ^a,c   Quiniou, Christiane ^a   Hou, Xin ^a   Kermorvant Duchemin, Elsa ^a,e   Hardy, Pierre ^a   Poitout, Vincent ^c,d   Chemtob, Sylvain ^a,c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^e CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

endothelial cell death; fatty acids; GPR40; neonatal hypoxia ischemia; transarachidonic acids

Indexed keywords

3 NITROTYROSINE; ARACHIDONIC ACID DERIVATIVE; G PROTEIN COUPLED RECEPTOR 40; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE SYNTHASE INHIBITOR; THROMBOSPONDIN 1; TRANSARACHIDONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DEGENERATION; BRAIN INFARCTION; BRAIN MICROCIRCULATION; CELL DEATH; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DENSITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOREACTIVITY; MICROANGIOPATHY; MICROVASCULATURE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT;

ANIMALS; ARACHIDONIC ACID; CEREBRAL INFARCTION; ENDOTHELIAL CELLS; FEMALE; HEK293 CELLS; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; MICE; MICE, INBRED C57BL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84876282899     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300943     Document Type: Article

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