PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling

Journal of Molecular and Cellular Cardiology

Volumn 66, Issue , 2014, Pages 83-93

  Yang, Jason H ^a   Polanowska Grabowska, Renata K ^a   Smith, Jeffrey S ^a   Shields, Charles W ^a   Saucerman, Jeffrey J ^a  

^a University of Virginia   (United States)

Author keywords

Compartmentation; Hypertrophy; Modeling; Nuclear; PKA; Adrenergic

Indexed keywords

CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPRENALINE;

ADRENERGIC TRANSMISSION; ANIMAL CELL; ARTICLE; BETA ADRENERGIC SIGNALING; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM;

3-ISOBYTL-1-METHYLXANTHINE; A-KINASE ANCHORING PROTEIN; AKAP; CAMP RESPONSE ELEMENT BINDING PROTEIN; COMPARTMENTATION; CREB; FORSKOLIN; FSK; HYPERTROPHY; IBMX; ISO; ISOPROTERENOL; MODELING; NES; NLS; NUCLEAR; NUCLEAR EXPORT SEQUENCE; NUCLEAR LOCALIZATION SEQUENCE; PDE; PHOSPHODIESTERASE; PKA; PKI; PP2A; PROTEIN KINASE A; PROTEIN KINASE INHIBITOR; PROTEIN PHOSPHATASE 2A; WGA; WHEAT GERM AGGLUTININ; Β-ADRENERGIC; Β-ADRENERGIC RECEPTOR; Β-AR;

ADRENERGIC BETA-AGONISTS; ANIMALS; ANIMALS, NEWBORN; CALCIUM; CALCIUM SIGNALING; CARDIOMEGALY; CATALYTIC DOMAIN; CELL NUCLEUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; GENE EXPRESSION REGULATION; ISOPROTERENOL; MODELS, STATISTICAL; MUSCLE CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84889065876     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.11.001     Document Type: Article

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