Cardiotoxic and cardioprotective features of chronic β-Adrenergic signaling

Circulation Research

Volumn 112, Issue 3, 2013, Pages 498-509

  Zhang, Xiaoying ^a   Szeto, Christopher ^a   Gao, Erhe ^b   Tang, Mingxin ^a   Jin, Jianguo ^a   Fu, Qin ^d   Makarewich, Catherine ^a   Ai, Xiaojie ^a,b   Li, Ying ^a,c   Tang, Allen ^a   Wang, Jenny ^a   Gao, Hui ^a   Wang, Fang ^a   Ge, Xinyi Joy ^a   Kunapuli, Satya P ^b   Zhou, Lin ^c   Zeng, Chunyu ^a,c   Xiang, Kevin Yang ^d,e   Chen, Xiongwen ^a  

^a Center for Translational Medicine   (China)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

apoptosis; Ca2+ calmodulin dependent protein kinase II; cAMP; exchange protein directly activated by cAMP; extracellular signal regulated kinases 1 2; protein kinase A inhibition

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE; RAC PROTEIN; RAP1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CELL DEATH; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITION; HEART FUNCTION; HEART HYPERTROPHY; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART PROTECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOMEGALY; CATS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; GREEN FLUORESCENT PROTEINS; HEART FAILURE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MYOCYTES, CARDIAC; RAC GTP-BINDING PROTEINS; RAP1 GTP-BINDING PROTEINS; RECEPTORS, ADRENERGIC, BETA; RECOMBINANT FUSION PROTEINS; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; STROKE VOLUME; TIME FACTORS; TRANSFECTION;

EID: 84873374748     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.273896     Document Type: Article

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