-
1
-
-
41449086790
-
Cardiac plasticity
-
Hill J.A., Olson E.N. Cardiac plasticity. N Engl J Med 2008, 358(13):1370-1380.
-
(2008)
N Engl J Med
, vol.358
, Issue.13
, pp. 1370-1380
-
-
Hill, J.A.1
Olson, E.N.2
-
2
-
-
39749168495
-
Tackling heart failure in the twenty-first century
-
Mudd J.O., Kass D.A. Tackling heart failure in the twenty-first century. Nature 2008, 451(7181):919-928.
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 919-928
-
-
Mudd, J.O.1
Kass, D.A.2
-
3
-
-
84862850069
-
Reverse remodeling in heart failure-mechanisms and therapeutic opportunities
-
Koitabashi N., Kass D.A. Reverse remodeling in heart failure-mechanisms and therapeutic opportunities. Nat Rev Cardiol 2011, 1-11.
-
(2011)
Nat Rev Cardiol
, pp. 1-11
-
-
Koitabashi, N.1
Kass, D.A.2
-
4
-
-
20044363270
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
-
Takimoto E., Champion H.C., Li M., Belardi D., Ren S., Rodriguez E.R., et al. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med 2005, 11(2):214-222.
-
(2005)
Nat Med
, vol.11
, Issue.2
, pp. 214-222
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Belardi, D.4
Ren, S.5
Rodriguez, E.R.6
-
5
-
-
33845474465
-
Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors
-
Xu D., Li N., He Y., Timofeyev V., Lu L., Tsai H.-J., et al. Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proc Natl Acad Sci U S A 2006, 103(49):18733-18738.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.49
, pp. 18733-18738
-
-
Xu, D.1
Li, N.2
He, Y.3
Timofeyev, V.4
Lu, L.5
Tsai, H.-J.6
-
6
-
-
47649122637
-
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy
-
Moens A.L., Takimoto E., Tocchetti C.G., Chakir K., Bedja D., Cormaci G., et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 2008, 117(20):2626-2636.
-
(2008)
Circulation
, vol.117
, Issue.20
, pp. 2626-2636
-
-
Moens, A.L.1
Takimoto, E.2
Tocchetti, C.G.3
Chakir, K.4
Bedja, D.5
Cormaci, G.6
-
7
-
-
0032544226
-
Regression of cellular hypertrophy after left ventricular assist device support
-
Zafeiridis A., Jeevanandam V., Houser S.R., Margulies K.B. Regression of cellular hypertrophy after left ventricular assist device support. Circulation 1998, 98(7):656-662.
-
(1998)
Circulation
, vol.98
, Issue.7
, pp. 656-662
-
-
Zafeiridis, A.1
Jeevanandam, V.2
Houser, S.R.3
Margulies, K.B.4
-
8
-
-
5444222884
-
Left ventricular assist device support reverses altered cardiac expression and function of natriuretic peptides and receptors in end-stage heart failure
-
Kuhn M., Voss M., Mitko D., Stypmann J., Schmid C., Kawaguchi N., et al. Left ventricular assist device support reverses altered cardiac expression and function of natriuretic peptides and receptors in end-stage heart failure. Cardiovasc Res 2004, 64(2):308-314.
-
(2004)
Cardiovasc Res
, vol.64
, Issue.2
, pp. 308-314
-
-
Kuhn, M.1
Voss, M.2
Mitko, D.3
Stypmann, J.4
Schmid, C.5
Kawaguchi, N.6
-
9
-
-
79751533489
-
Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study
-
Birks E.J., George R.S., Hedger M., Bahrami T., Wilton P., Bowles C.T., et al. Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study. Circulation 2011, 123(4):381-390.
-
(2011)
Circulation
, vol.123
, Issue.4
, pp. 381-390
-
-
Birks, E.J.1
George, R.S.2
Hedger, M.3
Bahrami, T.4
Wilton, P.5
Bowles, C.T.6
-
10
-
-
74549202707
-
Cardiovascular networks: systems-based approaches to cardiovascular disease
-
Lusis A.J., Weiss J.N. Cardiovascular networks: systems-based approaches to cardiovascular disease. Circulation 2010, 121(1):157-170.
-
(2010)
Circulation
, vol.121
, Issue.1
, pp. 157-170
-
-
Lusis, A.J.1
Weiss, J.N.2
-
11
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke J., Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006, 7(8):589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.8
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
12
-
-
36749021484
-
Linking microscopy and high content screening in large-scale biomedical research
-
Evans J.G., Matsudaira P. Linking microscopy and high content screening in large-scale biomedical research. Methods Mol Biol 2007, 356:33-38.
-
(2007)
Methods Mol Biol
, vol.356
, pp. 33-38
-
-
Evans, J.G.1
Matsudaira, P.2
-
13
-
-
84859628361
-
Automated image analysis identifies signaling pathways regulating distinct signatures of cardiac myocyte hypertrophy
-
Bass G.T., Ryall K.A., Katikapalli A., Taylor B.E., Dang S.T., Acton S.T., et al. Automated image analysis identifies signaling pathways regulating distinct signatures of cardiac myocyte hypertrophy. J Mol Cell Cardiol 2012, 10.1016/j.yjmcc.2011.11.009.
-
(2012)
J Mol Cell Cardiol
-
-
Bass, G.T.1
Ryall, K.A.2
Katikapalli, A.3
Taylor, B.E.4
Dang, S.T.5
Acton, S.T.6
-
14
-
-
84155186597
-
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes
-
Jentzsch C., Leierseder S., Loyer X., Flohrschütz I., Sassi Y., Hartmann D., et al. A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. J Mol Cell Cardiol 2012, 52(1):13-20.
-
(2012)
J Mol Cell Cardiol
, vol.52
, Issue.1
, pp. 13-20
-
-
Jentzsch, C.1
Leierseder, S.2
Loyer, X.3
Flohrschütz, I.4
Sassi, Y.5
Hartmann, D.6
-
15
-
-
78650979325
-
Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution
-
Prasad K.-M.R., Xu Y., Yang Z., Acton S.T., French B.A. Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution. Gene Ther 2011, 18:43-52.
-
(2011)
Gene Ther
, vol.18
, pp. 43-52
-
-
Prasad, K.-M.R.1
Xu, Y.2
Yang, Z.3
Acton, S.T.4
French, B.A.5
-
16
-
-
0018306059
-
A threshold selection method from gray-level histograms
-
Otsu N. A threshold selection method from gray-level histograms. IEEE Trans Syst Man Cybern 1979, 9(1):62-66.
-
(1979)
IEEE Trans Syst Man Cybern
, vol.9
, Issue.1
, pp. 62-66
-
-
Otsu, N.1
-
17
-
-
0026172104
-
Watersheds in digital spaces: an efficient algorithm based on immersion simulations
-
Vincent L., Soille P. Watersheds in digital spaces: an efficient algorithm based on immersion simulations. IEEE Trans Pattern Anal Mach Intell 1991, 13(6):583-597.
-
(1991)
IEEE Trans Pattern Anal Mach Intell
, vol.13
, Issue.6
, pp. 583-597
-
-
Vincent, L.1
Soille, P.2
-
18
-
-
33845792555
-
Cell Profiler: image analysis software for identifying and quantifying cell phenotypes
-
Carpenter A.E., Jones T.R., Lamprecht M.R., Clarke C., Kang I.H., Friman O., et al. Cell Profiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006, 7(10):R100.
-
(2006)
Genome Biol
, vol.7
, Issue.10
-
-
Carpenter, A.E.1
Jones, T.R.2
Lamprecht, M.R.3
Clarke, C.4
Kang, I.H.5
Friman, O.6
-
20
-
-
0037394610
-
Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes
-
Barron A.J., Finn S.G., Fuller S.J. Chronic activation of extracellular-signal-regulated protein kinases by phenylephrine is required to elicit a hypertrophic response in cardiac myocytes. Biochem J 2003, 371:71-79.
-
(2003)
Biochem J
, vol.371
, pp. 71-79
-
-
Barron, A.J.1
Finn, S.G.2
Fuller, S.J.3
-
21
-
-
15744393837
-
β-arrestin-dependent spontaneous α1a-adrenoceptor endocytosis causes intracellular transportation of α-blockers via recycling compartments
-
Pediani J.D., Colston J.F., Caldwell D., Milligan G., Daly C.J., Mcgrath J.C. β-arrestin-dependent spontaneous α1a-adrenoceptor endocytosis causes intracellular transportation of α-blockers via recycling compartments. Mol Pharmacol 2005, 67(4):992-1004.
-
(2005)
Mol Pharmacol
, vol.67
, Issue.4
, pp. 992-1004
-
-
Pediani, J.D.1
Colston, J.F.2
Caldwell, D.3
Milligan, G.4
Daly, C.J.5
Mcgrath, J.C.6
-
22
-
-
55449108079
-
Nuclear α1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes
-
Wright C.D., Chen Q., Baye N.L., Huang Y., Healy C.L., Kasinathan S., et al. Nuclear α1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. Circ Res 2008, 103(9):992-1000.
-
(2008)
Circ Res
, vol.103
, Issue.9
, pp. 992-1000
-
-
Wright, C.D.1
Chen, Q.2
Baye, N.L.3
Huang, Y.4
Healy, C.L.5
Kasinathan, S.6
-
23
-
-
0037163005
-
The myocardium-protective Gly-49 variant of the β1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation
-
Levin M.C., Marullo S., Muntaner O., Andersson B., Magnusson Y. The myocardium-protective Gly-49 variant of the β1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation. J Biol Chem 2002, 277(34):30429-30435.
-
(2002)
J Biol Chem
, vol.277
, Issue.34
, pp. 30429-30435
-
-
Levin, M.C.1
Marullo, S.2
Muntaner, O.3
Andersson, B.4
Magnusson, Y.5
-
24
-
-
0020523811
-
CGP 12177: a hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells
-
Staehelin M., Simons P., Jaeggi K., Wigger N. CGP 12177: a hydrophilic β-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells. J Biol Chem 1983, 258(6):3496-3502.
-
(1983)
J Biol Chem
, vol.258
, Issue.6
, pp. 3496-3502
-
-
Staehelin, M.1
Simons, P.2
Jaeggi, K.3
Wigger, N.4
-
25
-
-
3242752600
-
α1-Adrenoceptor antagonist properties of CGP 12177A and other β-adrenoceptor ligands: evidence against β3- or atypical β-adrenoceptors in rat aorta
-
Brahmadevara N., Shaw A.M., MacDonald A. α1-Adrenoceptor antagonist properties of CGP 12177A and other β-adrenoceptor ligands: evidence against β3- or atypical β-adrenoceptors in rat aorta. Br J Pharmacol 2004, 142(4):781-787.
-
(2004)
Br J Pharmacol
, vol.142
, Issue.4
, pp. 781-787
-
-
Brahmadevara, N.1
Shaw, A.M.2
MacDonald, A.3
-
26
-
-
0037275384
-
Evidence against β3-adrenoceptors or low affinity state of β1-adrenoceptors mediating relaxation in rat isolated aorta
-
Brahmadevara N., Shaw A.M., MacDonald A. Evidence against β3-adrenoceptors or low affinity state of β1-adrenoceptors mediating relaxation in rat isolated aorta. Br J Pharmacol 2003, 138(1):99-106.
-
(2003)
Br J Pharmacol
, vol.138
, Issue.1
, pp. 99-106
-
-
Brahmadevara, N.1
Shaw, A.M.2
MacDonald, A.3
-
27
-
-
0030969371
-
The cellular and molecular response of cardiac myocytes to mechanical stress
-
Sadoshima J., Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol 1997, 59(56):551-571.
-
(1997)
Annu Rev Physiol
, vol.59
, Issue.56
, pp. 551-571
-
-
Sadoshima, J.1
Izumo, S.2
-
28
-
-
0022558606
-
Binding of [3H]Prazosin to porcine aortic membranes: interaction of calcium antagonists with alpha-1 adrenoceptors
-
Nishimura J., Kanaide H., Nakamura M. Binding of [3H]Prazosin to porcine aortic membranes: interaction of calcium antagonists with alpha-1 adrenoceptors. J Pharmacol Exp Ther 1986, 236(3):789-793.
-
(1986)
J Pharmacol Exp Ther
, vol.236
, Issue.3
, pp. 789-793
-
-
Nishimura, J.1
Kanaide, H.2
Nakamura, M.3
-
29
-
-
0032442115
-
Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors
-
Daly C.J., Milligan C.M., Milligan G., Mackenzie J.F., Mcgrath J.C. Cellular localization and pharmacological characterization of functioning alpha-1 adrenoceptors by fluorescent ligand binding and image analysis reveals identical binding properties of clustered and diffuse populations of receptors. J Pharmacol Exp Ther 1998, 286(2):984-990.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, Issue.2
, pp. 984-990
-
-
Daly, C.J.1
Milligan, C.M.2
Milligan, G.3
Mackenzie, J.F.4
Mcgrath, J.C.5
-
30
-
-
0033913768
-
Quantitative imaging in live human cells reveals intracellular α1-adrenoceptor ligand-binding sites
-
Mackenzie J.F., Daly C.J., Pediani J.D., McGrath J.C. Quantitative imaging in live human cells reveals intracellular α1-adrenoceptor ligand-binding sites. J Pharmacol Exp Ther 2000, 294(2):434-443.
-
(2000)
J Pharmacol Exp Ther
, vol.294
, Issue.2
, pp. 434-443
-
-
Mackenzie, J.F.1
Daly, C.J.2
Pediani, J.D.3
McGrath, J.C.4
-
31
-
-
77954619980
-
Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression
-
Tadevosyan A., Maguy A., Villeneuve L.R., Babin J., Bonnefoy A., Allen B.G., et al. Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression. J Biol Chem 2010, 285(29):22338-22349.
-
(2010)
J Biol Chem
, vol.285
, Issue.29
, pp. 22338-22349
-
-
Tadevosyan, A.1
Maguy, A.2
Villeneuve, L.R.3
Babin, J.4
Bonnefoy, A.5
Allen, B.G.6
-
32
-
-
0041706091
-
Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes
-
Boivin B., Chevalier D., Villeneuve L.R., Rousseau E., Allen B.G. Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes. J Biol Chem 2003, 278(31):29153-29163.
-
(2003)
J Biol Chem
, vol.278
, Issue.31
, pp. 29153-29163
-
-
Boivin, B.1
Chevalier, D.2
Villeneuve, L.R.3
Rousseau, E.4
Allen, B.G.5
-
33
-
-
33744909351
-
Functional β-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes
-
Boivin B., Lavoie C., Vaniotis G., Baragli A., Villeneuve L.R., Ethier N., et al. Functional β-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes. Cardiovasc Res 2006, 71(1):69-78.
-
(2006)
Cardiovasc Res
, vol.71
, Issue.1
, pp. 69-78
-
-
Boivin, B.1
Lavoie, C.2
Vaniotis, G.3
Baragli, A.4
Villeneuve, L.R.5
Ethier, N.6
-
34
-
-
80051793072
-
Reversibility of adverse, calcineurin-dependent cardiac remodeling
-
Berry J.M., Le V., Rotter D., Battiprolu P.K., Grinsfelder B., Tannous P., et al. Reversibility of adverse, calcineurin-dependent cardiac remodeling. Circ Res 2011, 109:407-417.
-
(2011)
Circ Res
, vol.109
, pp. 407-417
-
-
Berry, J.M.1
Le, V.2
Rotter, D.3
Battiprolu, P.K.4
Grinsfelder, B.5
Tannous, P.6
-
35
-
-
77957729169
-
Patient-specific induced pluripotent stem-cell models for long-QT syndrome
-
Moretti A., Bellin M., Welling A., Jung C.B., Lam J.T., Bott-Flügel L., et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med 2010, 363(15):1397-1409.
-
(2010)
N Engl J Med
, vol.363
, Issue.15
, pp. 1397-1409
-
-
Moretti, A.1
Bellin, M.2
Welling, A.3
Jung, C.B.4
Lam, J.T.5
Bott-Flügel, L.6
|