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Volumn 18, Issue 1, 2011, Pages 43-52

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: In vivo gene delivery follows a Poisson distribution

Author keywords

AAV; cardiac troponin T promoter; cardiomyocyte specific; Poisson distribution

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; LUCIFERASE; PARVOVIRUS VECTOR; TROPONIN T;

EID: 78650979325     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2010.105     Document Type: Article
Times cited : (178)

References (42)
  • 1
    • 0034610388 scopus 로고    scopus 로고
    • Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart
    • Su H, Lu R, Kan YW. Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart. Proc Natl Acad Sci USA 2000; 97: 13801-13806.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13801-13806
    • Su, H.1    Lu, R.2    Kan, Y.W.3
  • 2
    • 0032902054 scopus 로고    scopus 로고
    • Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors
    • Svensson EC, Marshall DJ, Woodard K, Lin H, Jiang F, Chu L, et al. Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors. Circulation 1999; 99: 201-205.
    • (1999) Circulation , vol.99 , pp. 201-205
    • Svensson, E.C.1    Marshall, D.J.2    Woodard, K.3    Lin, H.4    Jiang, F.5    Chu, L.6
  • 3
    • 0345133487 scopus 로고    scopus 로고
    • Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine heart: Application to study of phospholamban physiology
    • Champion HC, Georgakopoulos D, Haldar S, Wang L, Wang Y, Kass DA. Robust adenoviral and adeno-associated viral gene transfer to the in vivo murine heart: application to study of phospholamban physiology. Circulation 2003; 108: 2790-2797.
    • (2003) Circulation , vol.108 , pp. 2790-2797
    • Champion, H.C.1    Georgakopoulos, D.2    Haldar, S.3    Wang, L.4    Wang, Y.5    Kass, D.A.6
  • 4
    • 0141502335 scopus 로고    scopus 로고
    • In vivo high-efficiency transcoronary gene delivery and Cre-LoxP gene switching in the adult mouse heart
    • Iwatate M, Gu Y, Dieterle T, Iwanaga Y, Peterson KL, Hoshijima M, et al. In vivo high-efficiency transcoronary gene delivery and Cre-LoxP gene switching in the adult mouse heart. Gene Therapy 2003; 10: 1814-1820.
    • (2003) Gene Therapy , vol.10 , pp. 1814-1820
    • Iwatate, M.1    Gu, Y.2    Dieterle, T.3    Iwanaga, Y.4    Peterson, K.L.5    Hoshijima, M.6
  • 5
    • 0032907636 scopus 로고    scopus 로고
    • Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector
    • Greelish JP, Su LT, Lankford EB, Burkman JM, Chen H, Konig SK, et al. Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector. Nat Med 1999; 5: 439-443.
    • (1999) Nat Med , vol.5 , pp. 439-443
    • Greelish, J.P.1    Su, L.T.2    Lankford, E.B.3    Burkman, J.M.4    Chen, H.5    Konig, S.K.6
  • 6
    • 0037166322 scopus 로고    scopus 로고
    • Cardiomyocyte-specific gene expression following recombinant adeno-associated viral vector transduction
    • Aikawa R, Huggins GS, Snyder RO. Cardiomyocyte-specific gene expression following recombinant adeno-associated viral vector transduction. J Biol Chem 2002; 277: 18979-18985.
    • (2002) J Biol Chem , vol.277 , pp. 18979-18985
    • Aikawa, R.1    Huggins, G.S.2    Snyder, R.O.3
  • 7
    • 33947288478 scopus 로고    scopus 로고
    • Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart
    • Prasad K-MR, Xu Y, Yang Z, Toufektsian M-C, Berr SS, French BA. Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart. Mol Ther: J Am Soc Gene Therapy 2007; 15: 764-771.
    • (2007) Mol Ther: J Am Soc Gene Therapy , vol.15 , pp. 764-771
    • K-Mr, P.1    Xu, Y.2    Yang, Z.3    Toufektsian, M.-C.4    Berr, S.S.5    French, B.A.6
  • 8
    • 33746874152 scopus 로고    scopus 로고
    • Adeno-associated virus serotypes: Vector toolkit for human gene therapy
    • Wu Z, Asokan A, Samulski RJ. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol Ther: J Am Soc Gene Therapy 2006; 14: 316-327.
    • (2006) Mol Ther: J Am Soc Gene Therapy , vol.14 , pp. 316-327
    • Wu, Z.1    Asokan, A.2    Samulski, R.J.3
  • 9
    • 33745143956 scopus 로고    scopus 로고
    • Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8
    • Inagaki K, Fuess S, Storm TA, Gibson GA, McTiernan CF, Kay MA, et al. Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol Ther: J Am Soc Gene Therapy 2006; 14: 45-53.
    • (2006) Mol Ther: J Am Soc Gene Therapy , vol.14 , pp. 45-53
    • Inagaki, K.1    Fuess, S.2    Storm, T.A.3    Gibson, G.A.4    McTiernan, C.F.5    Ma, K.6
  • 10
    • 33747518710 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduc-tion in vivo
    • Pacak CA, Mah CS, Thattaliyath BD, Conlon TJ, Lewis MA, Cloutier DE, et al. Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduc-tion in vivo. Circ Res 2006; 99: e3-e9.
    • (2006) Circ Res , vol.99
    • Pacak, C.A.1    Mah, C.S.2    Thattaliyath, B.D.3    Conlon, T.J.4    Lewis, M.A.5    Cloutier, D.E.6
  • 11
    • 35848961457 scopus 로고    scopus 로고
    • Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration
    • Bostick B, Ghosh A, Yue Y, Long C, Duan D. Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration. Gene Therapy 2007; 14: 1605-1609.
    • (2007) Gene Therapy , vol.14 , pp. 1605-1609
    • Bostick, B.1    Ghosh, A.2    Yue, Y.3    Long, C.4    Duan, D.5
  • 13
    • 19644378907 scopus 로고    scopus 로고
    • Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart
    • Wang Z, Zhu T, Qiao C, Zhou L, Wang B, Zhang J, et al. Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart. Nat Biotechnol 2005; 23: 321-328.
    • (2005) Nat Biotechnol , vol.23 , pp. 321-328
    • Wang, Z.1    Zhu, T.2    Qiao, C.3    Zhou, L.4    Wang, B.5    Zhang, J.6
  • 14
    • 1542347741 scopus 로고    scopus 로고
    • Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors
    • Thomas CE, Storm TA, Huang Z, Kay MA. Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors. J Virol 2004; 78: 3110-3122.
    • (2004) J Virol , vol.78 , pp. 3110-3122
    • Thomas, C.E.1    Storm, T.A.2    Huang, Z.3    Kay, M.A.4
  • 15
    • 34748831166 scopus 로고    scopus 로고
    • Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo
    • [erratum appears in Gene Ther 2007 Jul;14(13):1055]
    • Palomeque J, Chemaly ER, Colosi P, Wellman JA, Zhou S, Del Monte F, et al. Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo.[erratum appears in Gene Ther 2007 Jul;14(13):1055]. Gene Therapy 2007; 14: 989-997.
    • (2007) Gene Therapy , vol.14 , pp. 989-997
    • Palomeque, J.1    Chemaly, E.R.2    Colosi, P.3    Wellman, J.A.4    Zhou, S.5    Del Monte, F.6
  • 16
    • 56749104321 scopus 로고    scopus 로고
    • A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs
    • Yue Y, Ghosh A, Long C, Bostick B, Smith BF, Kornegay JN, et al. A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs. Mol Ther: J Am Soc Gene Therapy 2008; 16: 1944-1952.
    • (2008) Mol Ther: J Am Soc Gene Therapy , vol.16 , pp. 1944-1952
    • Yue, Y.1    Ghosh, A.2    Long, C.3    Bostick, B.4    Smith, B.F.5    Kornegay, J.N.6
  • 17
    • 33744900338 scopus 로고    scopus 로고
    • High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes
    • Gao G-P, Lu Y, Sun X, Johnston J, Calcedo R, Grant R, et al. High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes. J. Virol 2006; 80: 6192-6194.
    • (2006) J. Virol , vol.80 , pp. 6192-6194
    • Gao, G.-P.1    Lu, Y.2    Sun, X.3    Johnston, J.4    Calcedo, R.5    Grant, R.6
  • 18
    • 0034976642 scopus 로고    scopus 로고
    • The molecular genetic basis for hypertrophic cardiomyopathy
    • Marian AJ, Roberts R. The molecular genetic basis for hypertrophic cardiomyopathy. J Mol Cell Cardiol 2001; 33: 655-670.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 655-670
    • Marian, A.J.1    Roberts, R.2
  • 19
    • 1442325374 scopus 로고    scopus 로고
    • Cell-specific expression of SERCA, the exogenous Ca2+ transport ATPase, in cardiac myocytes
    • Ma H, Sumbilla CM, Farrance IKG, Klein MG, Inesi G. Cell-specific expression of SERCA, the exogenous Ca2+ transport ATPase, in cardiac myocytes. Am J Physiol - Cell Physiol 2004; 286: C556-C564.
    • (2004) Am J Physiol - Cell Physiol , vol.286
    • Ma, H.1    Sumbilla, C.M.2    Ikg, F.3    Klein, M.G.4    Inesi, G.5
  • 20
    • 10644289281 scopus 로고    scopus 로고
    • Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice
    • Nakai H, Fuess S, Storm TA, Muramatsu S-i, Nara Y, Kay MA. Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice. J Virol 2005; 79: 214-224.
    • (2005) J Virol , vol.79 , pp. 214-224
    • Nakai, H.1    Fuess, S.2    Storm, T.A.3    S-I, M.4    Nara, Y.5    Kay, M.A.6
  • 21
    • 0034654128 scopus 로고    scopus 로고
    • Electromagnetic guidance for catheter-based transendocardial injection: A platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models
    • Kornowski R, Leon MB, Fuchs S, Vodovotz Y, Flynn MA, Gordon DA, et al. Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models. J Am Coll Cardiol 2000; 35: 1031-1039.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1031-1039
    • Kornowski, R.1    Leon, M.B.2    Fuchs, S.3    Vodovotz, Y.4    Flynn, M.A.5    Gordon, D.A.6
  • 22
    • 34447251502 scopus 로고    scopus 로고
    • Adeno-associated viral vector-delivered hypoxia-inducible gene expression in ischemic hearts
    • Su H, Kan YW. Adeno-associated viral vector-delivered hypoxia-inducible gene expression in ischemic hearts. Methods Mol Biol 2007; 366: 331-342.
    • (2007) Methods Mol Biol , vol.366 , pp. 331-342
    • Su, H.1    Kan, Y.W.2
  • 23
    • 33645064807 scopus 로고    scopus 로고
    • Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors
    • Muller OJ, Leuchs B, Pleger ST, Grimm D, Franz W-M, Katus HA, et al. Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors. Cardiovasc Res 2006; 70: 70-78.
    • (2006) Cardiovasc Res , vol.70 , pp. 70-78
    • Muller, O.J.1    Leuchs, B.2    Pleger, S.T.3    Grimm, D.4    Franz, W.-M.5    Katus, H.A.6
  • 24
    • 37349108621 scopus 로고    scopus 로고
    • Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors
    • Raake PW, Hinkel R, Muller S, Delker S, Kreuzpointner R, Kupatt C, et al. Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors. Gene Therapy 2008; 15: 12-17.
    • (2008) Gene Therapy , vol.15 , pp. 12-17
    • Raake, P.W.1    Hinkel, R.2    Muller, S.3    Delker, S.4    Kreuzpointner, R.5    Kupatt, C.6
  • 25
    • 57749169283 scopus 로고    scopus 로고
    • AAV9 Provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat
    • Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, et al. AAV9 Provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Hum Gene Therapy 2008; 19: 1359-1368.
    • (2008) Hum Gene Therapy , vol.19 , pp. 1359-1368
    • Bish, L.T.1    Morine, K.2    Sleeper, M.M.3    Sanmiguel, J.4    Wu, D.5    Gao, G.6
  • 27
    • 0031691257 scopus 로고    scopus 로고
    • Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
    • (Erratum appears in J Virol 1999 Jan; 73(1):861)
    • Duan D, Sharma P, Yang J, Yue Y, Dudus L, Zhang Y, et al. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. (Erratum appears in J Virol 1999 Jan; 73(1):861). J Virol 1998; 72: 8568-8577.
    • (1998) J Virol , vol.72 , pp. 8568-8577
    • Duan, D.1    Sharma, P.2    Yang, J.3    Yue, Y.4    Dudus, L.5    Zhang, Y.6
  • 28
    • 0037333815 scopus 로고    scopus 로고
    • Genetic fate of recombinant adeno-associated virus vector genomes in muscle
    • Schnepp BC, Clark KR, Klemanski DL, Pacak CA, Johnson PR. Genetic fate of recombinant adeno-associated virus vector genomes in muscle. J Virol 2003; 77: 3495-3504.
    • (2003) J Virol , vol.77 , pp. 3495-3504
    • Schnepp, B.C.1    Clark, K.R.2    Klemanski, D.L.3    Pacak, C.A.4    Johnson, P.R.5
  • 30
    • 0042885512 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: A comparative study with adenovirus vectors
    • Vassalli G, Büeler H, Dudler J, Von Segesser LK, Kappenberger L. Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors. Inter J Cardiol 2003; 90: 229-238.
    • (2003) Inter J Cardiol , vol.90 , pp. 229-238
    • Vassalli, G.1    Büeler, H.2    Dudler, J.3    Von Segesser, L.K.4    Kappenberger, L.5
  • 31
    • 4444346479 scopus 로고    scopus 로고
    • Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors
    • Du L, Kido M, Lee DV, Rabinowitz JE, Samulski RJ, Jamieson SW, et al. Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors. Mol Ther 2004; 10: 604-608.
    • (2004) Mol Ther , vol.10 , pp. 604-608
    • Du, L.1    Kido, M.2    Lee, D.V.3    Rabinowitz, J.E.4    Samulski, R.J.5    Jamieson, S.W.6
  • 32
    • 0041308272 scopus 로고    scopus 로고
    • Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma
    • Barker SD, Dmitriev IP, Nettelbeck DM, Liu B, Rivera AA, Alvarez RD, et al. Combined transcriptional and transductional targeting improves the specificity and efficacy of adenoviral gene delivery to ovarian carcinoma. Gene Therapy 2003; 10: 1198-1204.
    • (2003) Gene Therapy , vol.10 , pp. 1198-1204
    • Barker, S.D.1    Dmitriev, I.P.2    Nettelbeck, D.M.3    Liu, B.4    Rivera, A.A.5    Alvarez, R.D.6
  • 33
    • 0033780918 scopus 로고    scopus 로고
    • Adeno-associated virus vector mediated gene transfer to pancreatic beta cells
    • Prasad KM, Yang Z, Bleich D, Nadler JL. Adeno-associated virus vector mediated gene transfer to pancreatic beta cells. Gene Therapy 2000; 7: 1553-1561.
    • (2000) Gene Therapy , vol.7 , pp. 1553-1561
    • Prasad, K.M.1    Yang, Z.2    Bleich, D.3    Nadler, J.L.4
  • 34
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 1998; 72: 2224-2232.
    • (1998) J Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 35
    • 0032857412 scopus 로고    scopus 로고
    • A helper virus-free packaging system for recombinant adeno-associated virus vectors
    • Collaco RF, Cao X, Trempe JP. A helper virus-free packaging system for recombinant adeno-associated virus vectors. Gene 1999; 238: 397-405.
    • (1999) Gene , vol.238 , pp. 397-405
    • Collaco, R.F.1    Cao, X.2    Trempe, J.P.3
  • 36
    • 0038150506 scopus 로고    scopus 로고
    • Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
    • Grimm D, Kay MA, Kleinschmidt JA. Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6. Mol Ther: J Am Soc Gene Therapy 2003; 7: 839-850.
    • (2003) Mol Ther: J Am Soc Gene Therapy , vol.7 , pp. 839-850
    • Grimm, D.1    Kay, M.A.2    Kleinschmidt, J.A.3
  • 37
    • 2642512201 scopus 로고    scopus 로고
    • Clades of Adeno-associated viruses are widely disseminated in human tissues
    • Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, et al. Clades of Adeno-associated viruses are widely disseminated in human tissues. J Virol 2004; 78: 6381-6388.
    • (2004) J Virol , vol.78 , pp. 6381-6388
    • Gao, G.1    Vandenberghe, L.H.2    Alvira, M.R.3    Lu, Y.4    Calcedo, R.5    Zhou, X.6
  • 39
    • 0029991350 scopus 로고    scopus 로고
    • Transfecting mammalian cells: Optimization of critical parameters affecting calcium-phosphate precipitate formation
    • Jordan M, Schallhorn A, Wurm FM. Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation. Nucleic Acids Res 1996; 24: 596-601.
    • (1996) Nucleic Acids Res , vol.24 , pp. 596-601
    • Jordan, M.1    Schallhorn, A.2    Wurm, F.M.3
  • 40
    • 0036229828 scopus 로고    scopus 로고
    • Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors
    • Ried MU, Girod A, Leike K, Buning H, Hallek M. Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors. J Virol 2002; 76: 4559-4566.
    • (2002) J Virol , vol.76 , pp. 4559-4566
    • Ried, M.U.1    Girod, A.2    Leike, K.3    Buning, H.4    Hallek, M.5


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