Dynamic protein kinase a activities induced by β-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction

Circulation Research

Volumn 104, Issue 6, 2009, Pages 770-779

  Soto, Dagoberto ^a   De Arcangelis, Vania ^a   Zhang, Jin ^b   Xiang, Yang ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adrenergic receptor; Contraction; Phospholamban; Protein kinase A phosphorylation

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLAMBAN; ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 1 ADRENERGIC RECEPTOR; CALCIUM BINDING PROTEIN; PHOSPHODIESTERASE IV;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEART MUSCLE CELL; MOUSE; MUSCLE FIBER CONTRACTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; HEART CONTRACTION; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ADRENERGIC ANTAGONISTS; ANIMALS; ANIMALS, NEWBORN; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; MALE; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION;

EID: 64249083698     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.187880     Document Type: Article

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